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Zugl.: Berlin, Humboldt-Universiẗat, Diss., 2006.

Using psychoanalysis as a theoretical framework, this essay examines the subject of escapism in The Picture of Dorian Gray by Oscar Wilde. Defense mechanisms of the ego, first thought of by Sigmund Freud, allow for a clearer understanding of what takes place during the plot. By taking the author’s background into account, along with clues in the plot of the novel, a more realistic reading of the novel is made possible instead of a supernatural take. A psychoanalytic perspective allows the essay to explore why and how the protagonist chooses to escape in the novel. The main focus of the analysis is how the protagonist of the novel carries the theme of escapism with increased intensity as the plot progresses. The essay considers why and how Dorian chooses to escape reality and utilizes the theoretical framework for two defense mechanisms used as an aid during escapist activities. Dorian progressively uses the defense mechanisms known as repression and rationalization to support his escapist behavior and protect his ego from anxiety derived from internal and external conflicts.

This thesis focuses on whether protest affects the levels of repression in electoral democracies and, if so, in what manner. After an overview of the literature, Chapter 2 contains an empirical analysis of the relationship between protest and repression at a global level, using a dataset of 71 democracies over 10 years. The results point to a positive association between protest and repression that is driven primarily by post-1974 democracies. The chapter then develops a theoretical model of the costs and benefits accruing to a democratic leader when deciding whether to repress a protest. The model yields a number of testable hypotheses about which factors will affect the likelihood that repression will be chosen, which are then tested for using cross-national and sub-national data. The impact of constitutional constraints is examined first using the cross-national dataset, which reveals that executives in new democracies centralise power in response to protest. Chapter 4 is a quantitative study of the 27 Brazilian states over a 9-year period using data on the repression of land protesters and political variables. The results indicate that governors with precarious political positions are less likely to promote repressive policing strategies. Chapter 5 uses data drawn from five Brazilian national newspapers to identify whether under-reporting of land protest events might contribute to the level of state repression. Chapter 6 is a qualitative comparison of two states – São Paulo and Pará – and suggests that while tight political control over the police explains repression in the former, the unaccountability of the police and the ideology of the main opposition parties in the state assembly may explain why the latter has a much higher level of repression than would be predicted by political factors alone. Chapter 7 revisits the cross-national dataset of 71 democracies to test whether additional determinants of repression identified in Chapter 6 have an effect at the global level.

Thesis (MSc)--University of Stellenbosch, 2000. / ENGLISH ABSTRACT: The wine yeast Saccharomyces cerevisiae has the ability to utilize several different nitrogenous compounds to fulfill its metabolic requirements. Based upon different growth rates of the yeast in a particular nitrogen source, nitrogen compounds have been classified as either good or poor nitrogen sources. In an environment which contains different quality nitrogen sources, such as grape must, the yeast first utilizes good and then the poor nitrogen sources. This discrimination between good and poor nitrogen sources is referred to as nitrogen catabolite repression (NCR). Examples of good nitrogen sources are ammonia, glutamine and asparagine. Nitrogen sources such as allantoin, y-aminobutyrate (GABA), arginine and proline are poor quality nitrogen sources. Several regulatory proteins, Ure2p, Gln3p, Da180p,Gat1pand Deh1p, mediate NCR in S. cerevisiae. These trans-acting factors regulate transcription of NCR sensitive genes. All these proteins, except Ure2p, bind cis-acting elements in the promoters of genes that are responsible for degradation of poor nitrogen sources. Gln3p is an activator of NCR sensitive genes in the absence of good nitrogen sources. The predominant mechanism by which NCR functions is by using Ure2p to inactivate the activator Gln3p in the presence of a good nitrogen source. Several research groups have studied the Ure2p, mainly due to its prion-like characteristics. The Ure2p has two domains: a prion inducing domain located in the N-terminal region and a NCR regulatory domain located in the C-terminal domain. The aims of this study were (i) to determine the part of the C-terminal domain which is responsible for NCR, (ii) to establish if ure2 deletion mutants produce less ethyl carbamate during wine fermentations and (iii) if NCR functions in industrial yeast strains. Nested deletions of the URE2 gene revealed that the NCR regulatory domain resides in the last ten amino acids of the Ure2p. This was established by Northern blot analysis on the NCR sensitive genes DAL5, CAN1, and GAP1 genes. Ethyl carbamate in wine is produced by spontaneous chemical reaction between urea and ethanol in wine. Urea is produced by S. cerevisiae during the metabolism of arginine. Arginine is degraded to ornithine and urea by arginase, the product of the CAR1 gene. Degradation of urea by S. cerevisiae is accomplished by urea amidolyase, a bi-functional enzyme and product of the DUR1,2 gene which is subject to NCR. This study investigated if a ure2 mutant strain produced less ethyl carbamate during wine fermentations. Wine fermentations were conducted with diploid laboratory strains: a ure2 mutant strain and its isogenic wild type strain. GC/MS analysis of the wine revealed that the ure2 mutant produced less ethyl carbamate but more ethanol than the wild type strain when arginine, di-ammoniumphosphate, asparagine or glutamine were added as nitrogen sources, in combinations and separately. There was no significant difference between the wild type fermentation and the ure2 mutant fermentation when no nitrogen was added. It was found that a combination between the deletion of URE2 and the addition of a good nitrogen source resulted in lower levels of ethyl carbamate. High density micro array analysis done on an industrial strain wine yeast in Chardonnay grape must revealed that the GAP1, CAN1, CAR1 and DUR1,2 genes, responsible for transport and metabolism of arginine and degradation of urea, are NCR sensitive. These data strongly suggest that NCR functions in industrial yeast strains. / AFRIKAANSE OPSOMMING: Die wyngis Saccharomyces cerevisiae kan verskillende stikstofbronne gebruik om in sy stikstofbehoeftes te voldoen. Stikstofbronne word as goeie of swak stikstofbronne geklassifiseer op grond van die groeitempo van die gis op die betrokke stikstofbron. 'n Goeie stikstofbron laat die gis vinniger groei as wat dit op 'n swak stikstofbron sou groei. In omgewings soos druiwemos waar daar 'n verskeidenheid van stikstofbronne teenwoordig is, sal die gis eers die goeie bronne en daarna die swak bronne benut. Stikstofbronne soos ammonium, asparagien en glutamien word geklassifiseer as goeie bronne. Allantoïen, y-amino-butaraat (GABA), prolien en arginien word as swak stikstofbronne geklassifiseer. Die meganisme waarmee S. cerevisiae tussen die stikstofbronne onderskei, staan as stikstof kataboliet onderdrukking (NCR) bekend. Die proteïene wat vir verantwoordelik is NCR naamlik Ure2p, Gln3p, Gat1 p, Dal80p en Deh1 p, bind met die uitsondering van Ure2p, almal aan cis-werkende elemente in die promoters van NCR-sensitiewe gene. Die trans-werkende faktore reguleer die transkripsie van NCR-sensitiewe gene. NCR werk hoofsaaklik deur die inhibering van Gln3p deur Ure2p in die teenwoordigheid van 'n goeie stikstofbron. Die oorgrote meerderheid NCR-sensitiewe gene word deur Gln3p in die afwesigheid van 'n goeie stikstofbron geaktiveer. Heelwat navorsing is op die prionvormings vermoë van Ure2p gedoen. Ure2p het twee domeine: 'n N-terminale domein wat vir prionvorming verantwoordelik is en die C-terminale domein waar die NCR funksie van Ure2p gesetel is. Die doel van die studie was (i) om te bepaal waar in die C-terminale domein van Ure2p die NCR regulering geleë is, (ii) of ure2 delesie mutante minder etielkarbamaat tydens wynfermentasies produseer en (iii) of NCR in industriële gisrasse funksioneel is. Delesie analises van URE2 het getoon dat die NCR regulerings domein in die laaste tien aminosure gesetel is. Dit is vas gestel m.b.v. noordlike klad tegniek analises op die OALS, CAN1 en GAP1 gene.Etielkarbamaat in wyn word deur die spontane chemiese reaksie tussen ureum en alkohol geproduseer. Ureum word gedurende die metabolisme van arginien in S. cerevisiae geproduseer. Arginien word deur arginase, produk van die CAR1 geen, na ornitien en ureum afgebreek. Die bi-funksionele ureum amidoliase, gekodeer deur die DUR1,2 geen, breek ureum na CO2 en NH/ af. As gevolg van die NCRsensitiwiteit van dié gene is ondersoek ingestel na In ure2 mutant se vermoë om minder etielkarbamaat tydens wynfermentasies te produseer. Chardonnay druiwemos is met In diploiede laboratorium ras en die isogeniese ure2 mutant gefermenteer. GC/MS analise op die wyn het getoon dat die ure2 mutant minder etielkarbamaat, maar meer alkohol in vergelyking met die wilde tipe gis produseer, as arginien, di-ammoniumfosfaat, asparagien en glutamien, afsonderlik of gesamentlik byvoeg is. Daar was egter nie In merkwaardige verskil tussen die fermentasies waar geen stikstof bygevoeg is nie. Dit dui daarop dat In kombinasie van In URE2 delesie en die byvoeging van stikstof etielkarbamaat vlakke verlaag. Mikro-skyfie analise van In industriële gis in Chardonnay mos het getoon dat die GAP1, CAN1, CAR1 en DUR1,2 gene wat verantwoordelik is vir die transport en metabolisme van arginien en degradasie van ureum, wel NCR-sensitief is. Dit dui daarop dat NCRwel in industriële gisrasse funksioneel is.

<p>This thesis deals with the question of how Swedish society responds when juveniles commit crimes. The focus is social work co-operating with the legal system and the interaction between these two. The aim of this study is to make visible/analyse factors that affect the choice between treatment and correction of juveniles in an emergency situation, when there is a necessity to choose between immediate preventative custody on the one hand, and detention on the other. This study analyses the selection through outcome patterns. Theoretically the base is six concepts; system/practice, and treatment/correction. Together they form a model where the actors (the social services/the police/the attorney/county administrative courts/district courts) on this juvenile field can be situated. The strategies of the actors’ decision-making are implied by either norm-rational decision-making or goal-rational decision-making. Empirical data is studied through records of immediate custody and detention of juveniles aged 15-18 years old. The immediate denial of freedom represents, in the Swedish legislation, a process whereby social services and law enforcers meet and decide whether to treat or correct the juvenile. This selection is the focus of the empirical study of this thesis. In 1992, 1998 and 2003 a national overall survey was made of all juveniles aged 15-18 years that have been either in immediate custody or in detention or both. Documentation was obtained from the courts. The results show that the general denial of freedom of juveniles have increased greatly during the years 1992, 1998 and 2003, and especially from 1998 to 2003. Almost all of the acts concern boys, even though girls are making at break-through in 2003. There are differences between the groups that either have been in detention or in immediate custody in ways of “survey-year”, “ethnic background”, “age” and “categorising of crime”. This study shows a large discrepancy between legislation and the legal practice.</p>

In a study using 73 females and 30 male undergraduates, information on the basic dimensions of Millon's eight personality styles was obtained from correlations of the Millon Behavioral Health Inventory with Rotter's I-E scale and Byrne's R-S scale. Hypotheses predicting a significant relationship between the active-passive and repression-sensitization were generally supported. Predictions of a significant relationship between the dependent-indepenent dimension and generalized expectancy of locus of control were not supported. Implications of these findings for the efficacy of Millon's system are discussed, along with future research possibilities.

The Purpose of this study was to investigate the relationship of the repression-sensitization dimension and leisure preferences, specifically threatening versus nonthreatening physical activity and television program preferences. The hypotheses were that sensitizers would prefer threatening (violent) television programs and threatening (competitive) physical activities to a significantly greater degree than repressors. Sixty college undergraduates were designated repressors, sensitizers, or middle group by their scores on Byrne's Repression-Sensitization Scale. Preference sheets determined subjects' preferences for threatening and nonthreatening television programs and physical activities. Simple analyses of variance revealed no significant differences in repressors', sensitizers', or middle group's preferences for threatening television programs or physical activities, and thus the hypotheses were rejected. Non-significant tendencies in the data, in hypothesized directions, suggest further research.

From 1919 to 1920 the United States carried out a massive campaign against radicals, arresting and deporting thousands of radical immigrants in a matter of months, raiding and shutting down anarchist printing shops, and preventing anarchists from sending both periodicals and personal communications through the mail. This period is widely known as the First Red Scare, and is framed as a reaction to recent anarchist terrorism, syndicalist unionizing, and the Bolshevik Revolution. Though the 1919-20 First Red Scare was certainly unprecedented in its scope, it was made possible through a longer campaign against radicals, throughout which the US government constructed legal, ideological, and institutional apparatuses to combat radicalism and terrorism. This project explores the longer conflict between the US government and anarchists, focusing on the period between 1900 and 1920. It argues that the government sought to suppress radicalism not just due to anarchist terrorism or class antagonism, but also due to a broader ideology of antiradicalism that framed anarchist counterculture and connected ideas like free love and internationalism as a threat to the nation-state and to traditional American values. In trying to suppress radical counterculture years before the First Red Scare, the US government built its capacity for federal policing. And, by tying the battle against anarchist terrorism to a broader project of suppressing any idea considered to be radical or nontraditional, the US government controlled the kinds of ideas and people allowed within American borders through force, demarcating political limits to American nationality and citizenship.

Mast cells are potent effectors of the inflammatory response, playing an important role in atopy, bacterial immunity, and animal models of arthritis, multiple sclerosis, and heart disease. Hence controlling mast cell numbers and responsiveness is essential for preventing inflammatory disease. This work demonstrated that the cytokine TGF-β1 is a potent inducer of mast cell apoptosis, a finding that was consistent for cultured mouse bone marrow-derived mast cells, peritoneal mast cells, and human mast cells. Cell death appeared to be the result of TGF-mediated repression of IL-3 receptor expression and function, leading to mitochondria1 damage and activation of an apoptotic cascade acting via p53 and caspases. While IL-3 receptor expression was reduced within one day of TGF-βl stimulation, apoptosis required at least 3 days to occur. This delay in onset is postulated to allow for protective mast cell effector functions, protecting the host from infection while preventing the establishment of chronic inflammation. These studies support the theory that TGF- β1 is an inhibitor of mast cell survival. Because of the widespread expression of TGF-β1, this cytokine may be an ideal candidate for control of mast cell homeostasis.