Thesis (M.S.)--Virginia Polytechnic Institute and State University, 1993. / Vita. Abstract. Includes bibliographical references (leaves 72-74). Also available via the Internet.

Thesis (M. Sc.)--Carleton University, 2008. / Includes bibliographical references (p. 71-81). Also available in electronic format on the Internet.

Thesis (MSc Consumer Sc)--Stellenbosch University, 2002. / ENGLISH ABSTRACT: Food allergies in children are a growing problem and have various effects on these children, their households, the community and the economy. No medication or cure is currently available to consumers suffering from food-allergies. Medical teams are aware of the patients' need for support, but information is lacking and understanding of their basic needs and problems neglected. Two qualitative research methods, namely the focus group technique and case studies were used to investigate the emotional and physical environment of children allergic to wheat, soy, cow's milk and egg respectively. Five focus group meetings were conducted with the caregivers of food-allergic children. Two during the pilot study and three in the main study. A total of twenty three participants attended the three meetings of the main study. A meeting schedule was developed and the meetings carefully moderated. After the data had been obtained from the focus group meetings, there was a need for more in-depth information and understanding. Seven of the participants of the focus groups were identified, through developed criteria, to be further investigated as case studies. Five units of investigation were identified for the case studies. It was the (i) caregiver, (ii) allergic child, (iii) other children, (iv) "non-caregiver parent" and (v) household. Some of the matters that were investigated in both the focus groups and case studies were health consciousness, menu planning, recipe needs and use, reading of food labels, hidden allergens and the social and emotional effects of having and being a food-allergic child. A great need for better support and educational programs to assist these households were identified. Very few of the households were health conscious, while they all experienced problems with menu planning, identifying hidden allergens and suffered from social and or emotional problems. Very few participants made use of recipes or identified a need for allergen-free recipes. After having gained insight in the daily lives of these households, four - virtually identical, two-week menu cycles were developed to suit the life style requirements and restrictions of these children. The same recipes were used, but allergens omitted, replacements made and the recipes adapted as necessary. Product scouting was done for hidden allergens in selected popular convenience foods, especially those from the lowest level of the USDA Food Guide Pyramid. Hidden allergens appeared to be a problem when food is prepared and bought for the food allergic child. It should be taken into account that despite the information stated on the food label undeclared allergens might still be present in food. The two-week menu cycle for the child allergic to cow's milk was then quantitatively evaluated for nutritional adequacy by FoodFinder ™ 2 - a software program, for children aged between seven and ten years. All the macronutrients and micronutrients identified by the National Survey in 1999 as insufficient «67% of the RDA) among South African children aged between one and nine years, were evaluated as well as those mentioned in the WHO Dietary and Health Goals. All the nutrients were sufficient, except for calcium and Vitamin D. Supplementation is advised. The sensory acceptability of the menu-items in the two-week menu cycles were not evaluated. A vast number of issues pertaining to the food-allergic child require further research. A great need exists for the development of educational programs to support the households with food-allergic children. The identification of hidden allergens and the development of reliable sensory testing models for food-allergic children are all areas that should urgently be researched further. / AFRIKAANSE OPSOMMING: Voedsel-allergieë by kinders is 'n groeiende probleem met 'n verskeidenheid effekte op dié kinders, hulle huishoudings, die gemeenskap en die ekonomie. Tans is geen medikasie of kuur teen voedsel-allergieë beskikbaar nie. Mediese spanne is bewus van die behoefte aan sorg en leiding wat deur dié spesifieke groep verbruikers benodig word, maar inligting oor hulle behoeftes en probleme is ontoereikend. Twee kwalitatiewe navorsingsmetodes, naamlik die fokusgroeptegniek en gevallestudies, is gebruik om die emosionele en fisiese omgewing van kinders allergies vir onderskeidelik grane, soja, melk en eiers te ondersoek. Tydens 'n voorloperstudie is twee fokusgroepvergaderings gehou. Vir die hoofstudie is drie fokusgroepvergaderings met versorgers van kinders met 'n voedsel-allergie gehou met 'n totaal van drie en twintig deelnemers. 'n Vergaderingskedule is ontwikkel en die vergaderings is sorgvuldig gemodereer. Nadat die data van die fokusgroepe ingesamel is, was daar behoefte aan meer in diepte inligting en begrip. Aan die hand van ontwikkelde kriteria is sewe van die deelnemers aan die fokus groepe as gevallestudies geselekteer. Vyf eenhede van ondersoek is geïdentifiseer vir die gevallestudies. Dit is: (i) die allergiese kind, (ii) versorger, (iii) ander kinders, (iv) die "nie-versorgende" ouer en (v) die huishouding. Sommige van die aspekte wat in beide die fokusgroepe en gevallestudies ondersoek is, was gesondheidsbewustheid, spyskaartbeplanning, die gebruik en behoefte aan resepte, lees van voedseletikette, verskuilde allergene en die sosiale en emosionele effek van 'n voedsel-allergie op die kind sowel as die ouers. 'n Groot behoefte aan beter ondersteuning en opvoedkundige programme, om hierdie huishoudings te help, is geïdentifiseer. Baie min van die huishoudings was werkilk gesondheidsbewus, terwyl hulle almal probleme met spyskaartbeplanning, identifisering van verborge allergene en sosioemosionele probleme ondervind het. Weinig van die deelnemers het gebruik gemaak van resepte of het 'n behoefte aan allergeen-vrye resepte ondervind. Nadat insig in die daaglikse lewenstyl van hierdie huishouding verkry is, is vier amper-identiese twee-weekse siklusspyskaarte ontwikkel wat die lewenstyl en behoeftes van hierdie huishoudings aanspreek. Dieselfde resepte was gebruik vir al vier twee-weeksiklusspyskaarte, met die verskil dat verskillende allergene vervang is, na gelang van die allergie verskillende behoefte. Marknavorsing is gedoen op alledaagse produkte en is hoofsaaklik gefokus op die produkte wat die basis van die voedselpiramide uitmaak. Daar is bevind dat verskeulde allergene voorkom in produkte waar dit nie verwag word nie, en soms selfs nie op die voedseletikette verklaar word nie. Die twee-weeksiklusspyskaart van die melk-allergiese kind is kwantitatief ge-evalueer vir toereikendheid van die dieet vir kinders tussen die ouderdomme sewe tot tien jaar op die Foodfinder TM 2 - sagteware program. Die makro- en mikronutriente wat volgens 'n nasionale opname in 1999 as problematiese «67% van die RDA) vir kinders in die ouderdomsgroep een tot nege, uitgewys is, is geneem en die voedingstowwe is ook teen die Werêld Gesondheidsorganisasie (WHO) se dieetdoelwitte getoets. AI die nutriënte was voldoende volgens die analise, behalwe kalsium en Vitamen D. Supplementasie word aanbeveel vir dié twee nutriënte. Die sensoriese aanvaarbaarheid van die spyskaartitems in die siklusspyskaart is nie getoets nie. Verskeie aspekte wat vorendag gekom het, benodig verdere navorsing. 'n Groot behoefte aan die ontwikkeling van opvoedkundige programme, wat die huishoudings met voedsel-allergiese kinders ondersteun, bestaan. Die identifikasie van verskuilde allergene en die ontwikkeling van 'n beproefte sensoriese toetsmodel vir voedsel-allergiese kinders is potensiële gebiede wat dringend verder nagevors behoort te word.

Thesis (MNutr)--Stellenbosch University, 2014. / ENGLISH ABSTRACT: Objective: The objective of the study was to assess and compare the level of knowledge of South African health professionals) treating patients with Type 1 and Type 2 Diabetes Mellitus (T1 and T2 DM) with regard to nutrition and Diabetes Self-management (DSM). To achieve this objective, two questionnaires (one for T1 DM and one for T2 DM) was developed and validated. In addition the study identifies the areas in need for further education as well as to assess if socio-demographic factors influence the level of knowledge. Methods: The questionnaires were developed by: i) planning and developing constructs on nutrition and DSM by experts (n = 2) in the field of nutrition and diabetes care, ii) compilation and evaluation of a pool of 60 questions for face and content validity by an expert panel comprising six Registered Nurses / Diabetes Educators (RN / DE) and registered dieticians (RD) and iii) testing the questionnaires for criterion validity and reliability by a pilot group (n = 34 RN / DE and RD). Chronbach’s alpha values were calculated to determine validity and questions were disregarded or changed depending on this outcome. These questionnaires were then sent via electronic and hard mail to a randomised sample of RD (n = 1200) and RN / DE (n = 498). Data of 70 questionnaires on T1 DM and 105 on T2 DM was coded and analysed. The cut off value of 70% was considered as adequate knowledge. Results: With regard to questionnaire development, constructs were eliminated by the expert panel and this resulted in the acceptance of 60 constructs for the final questionnaires. Five constructs were replaced to improve content validity and an additional three constructs were adjusted to improve face validity. Recommended amendments were made to improve the criterion validity of the questionnaires. Internal consistency was shown with an overall Cronbach’s alpha value of 0.73 for the T1 DM questionnaire and 0.71 for the T2 DM questionnaire. In terms of the assessment of knowledge for T1 DM, the RD (75.4%) but not the RN/DE (67.2%) had adequate knowledge of nutrition. This was not statistically significant different from the RN / DE (p = 0.07). Both groups scored equally with regard to their knowledge of DSM with scores indicating inadequate knowledge (64.7% and 64.9% respectively) (p = 0.27). For T2 DM, the RD (74.6%) but not the RN / DE (61.6%) showed their knowledge of nutrition to be adequate, and statistically significantly better than the RN / DE (p = 0.0005). Both groups showed inadequate knowledge of DSM (56.0% and 61.9% respectively) (p = 0.31). The main areas of knowledge for diabetes mellitus (DM) identified in need for further education were the glycaemic index (GI) values of food, carbohydrate counting, the use of sugars / sweeteners, timing of meals and snacks with regard to activity, medication used, treatment of hypo- and hyperglycaemia and the use of alcohol. Age affected knowledge (for both nutrition and DSM) with regard to T1 DM, as the age group 30 - 49 years scored significantly better than the rest (nutrition p = 0.005, DSM p = 0.006 respectively). Health professionals in the private sector achieved higher scores compared to those working in the public sector (nutrition p = 0.011, DSM p = 0.016 respectively). Conclusion: Two valid and reliable quantitative questionnaires comprising 4 sections and 30 questions were developed to assess the level of knowledge of health professionals (RN / DE and RD) on nutrition and DSM treating patients with T1 and T2 DM in South Africa. RN / DE required further education towards key nutrition concepts and RN / DE and RD required further education on key concepts regarding DSM for both T1 and T2 DM. / AFRIKAANSE OPSOMMING: Doel: Die doel van die studie was om die hoeveelheid van kennis van verpleeg en dieetkunde personeel wat persone met Tipe 1 en Tipe 2 Diabetes Mellitus (T1DM en T2DM) in Suid – Afrika behandel, te bepaal en te vergelyk. Die studie het gefokus op kennis t.o.v. voeding en diabetiese self-sorg. Om die doel te bereik was twee vrae lyste, een vir T1 DM en een vir T 2 DM ontwikkel. Die verskillende aspekte van kennis wat verdere opleiding benodig is geidentifiseer asook of enige demografiese faktore wat kennis kon beinvloed. Metode: Die volgende stappe was geneem om voldoende geldigheid en betroubaarhied te bereik: 1. Twee kenners het verskeie belangrike aspekte van voeding en diabetiese self-sorg geidentifiseer en ontwikkel. 2. ‘n Paneel van 34 geregistreerde dieetkundiges en verpleeg personeel wat in Diabetes Mellitus spesialiseer , het die inhoud van ‘n totaal van 60 vrae ge- evalueer vir geldigheid en toepaslikheid. 3. Die paneel het die vraelyste verder ge- evalueer vir ‘n aanvaarbare standard van betroubaarheid. Chronbach-alfa waardes was gebruik vir die aanvaarbaarheid van alle vrae. 4. Die finale weergawe van 30 aanvaarbare vrae in elke vraelys was gestuur via elektroniese en normale pos na 1200 RD en 489 verpleegpersoneel wat spesialiseer in T1 en T2 DM. 5. Inligting van onderskeidelik 70 T1DM en 105 T2 DM vraelyste was gekodeer en ge-analiseer. Resultate: Tydens die ontwikkeling van die vraelyste, was sekere aspekte van kennis deur die twee kenners ge-elimineer. Die evaluering van die groep van dieetkundiges en verpleeg personeel het verder bygedra tot die vervanging en aanpassing van sekere aspekte van kennis. Dit het bygedra tot die vlak van voldoende geldigheid en toepaslikheid. Vir voldoende betroubaarheid was die Chronbach- alfa waardes van 0.73 vir T1DM and 0.71 vir T2 DM onderskeidelik aanvaar. Die studie het getoon dat die dieetkundiges voldoende kennis besit t.o.v. voeding vir T1 DM (75.4%). Dit was egter nie statisties betekenisvol meer in vergelyking met die kennis soos behaal deur die verpleegpersoneel (62.2%) (p = 0.07). Beide groepe se kennis t.o.v diabetiese self sorg was bepaal as onvoldoende met onderskeidelik 64.7% en 64.9%. In terme van T2 DM, het die dieetkundiges statisties betekenisvol beter kennis getoon vir voeding (74.6%) in vergelyking met die vlak van kennis soos behaal deur die verpleeg personeel (61.6%) (p = 0.0005). Soos in die geval van T1 DM het beide groepe onvoldoede kennis getoon vir diabetiese self sorg met onderskeidelike waardes van 56.0% en 61.9%. (p = 0.31). Die areas van kennis wat geidentifiseer was vir verdere opleidig, was die glisemiese indeks van voedsel, bepaling van die hoeveelheid koolhidrate in voedsel, die gebruik van suiker en versoeters, die neem van maaltye en versnapperinge, oefening, medikasie, voorkoming van lae en hoe blood glukose vlakke asook die gebruik vam alkoholiese drankies. Die ouderdoms groep tussen 30-49 jaar het statisties ‘n hoer vlak van kennis getoon vir beide voeding (p = 0.005) en diabetiese self sorg (p = 0.006) vir T 1 DM in vergelyking met die ander ouderdoms groepe. Personeel wat in die private sektor werk het ‘n beter vlak van kennis getoon in vergelyking met personeel wat in die openbare sektor werk (p = 0.011 en p = 0.016 vir voeding en diabetiese self sorg onderskeidelik. Samevatting: Twee geldige en betroubare vrae lyste met 30 vrae in totaal was ontwikkel om die vlak van kennis van dieetkundiges en verpleeg personeel te bepaal in terme van voeding en diabetiese self sorg vir beide T1 en T2 DM. Die verpleegpersoneel benodig verder opleiding t.o.v sekere aspekte van voeding en diabetiese self -sorg en die dieetkundiges t.o.v. diabetiese self -sorg vir beide T1 en T2 DM.

The diploma thesis deals with the diet during the diabetes mellitus type 2 disease and with possibilities of enriching the diabetic?s diet. The theoretical part of the thesis is focused on the description of this disease and the topic of the diet therapy ? what diets can be followed by diabetes patients and whether the diet is appropriate. The practical part of the thesis is dealing with the enrichment of the diabetic diets. Results of the questionnaire shown which meals are missed by the diabetics and for some of them were designed the recipes. According to the recipes were cooked diabetic dishes which were after that given to tasting and rating. Based on the statistic test and results of the rating dishes were evaluated to decide which are preferred to put in diabetic diet and which are not. I also prepared one exemplary menu including mentioned dishes.

O estudo avaliou o consumo de magnésio na dieta de praticantes de musculação (n = 15) de acordo com as novas Ingestões Dietéticas de Referência (lDRs). Também foram identificados os alimentos fonte de magnésio na dieta do grupo estudado e em maratonistas da mesma faixa etária, para serem reproduzidos e analisados em seu conteúdo de magnésio total. Desta forma, podem-se comparar os resultados obtidos em laboratório com os encontrados em tabelas de composição de alimentos. Realizando-se ainda a validação de metodologia de determinação de magnésio total. O consumo dietético de Mg (média±desvio padrão) foi 323±115 mgMg/d e 115±26 mgMg/1000kcal na faixa dos 19-30 anos e 345±110 mgMg/d e 110±18 mgMg/1000kcal na faixa dos 31 a 50 anos, sem diferenças significantes entre os grupos estudados. Neste quadro, 5 praticantes de musculação tinham a probabilidade mínima de 70% de estarem com a ingestão usual de Mg adequada, enquanto 6 mostraram a probabilidade mínima de 70% de ingestão usual de Mg inadequada. Deve-se ainda ressaltar um melhor aporte dietético do mineral em questão, enfatizando um maior consumo de alimentos com maior conteúdo de magnésio. As principais fontes alimentares de Mg para o grupo da musculação foram banana, bife, batata cozida, espinafre cozido, feijão, leite semi-desnatado e aveia em flocos. Já para os maratonistas estas foram representadas por banana, farinha de milho, farelo de aveia, feijão, bife, peixe cozido, quiabo, achocolatado em pó, pão integral e mandioca . A curva de calibração de magnésio encontrado foi linear (r = 0,9999), apresentando LO e LQ (Média±desvio padrão) 0,15±0,17 e 0,48±0,55 &#181;gMg/mL. Para determinação de magnésio total os padrões de referência certificado (NIST) e secundário (AIN93G) apresentaram coeficiente de variação (c.v.) 4,4 e 3,2 %, respectivamente. Porém, a concentração obtida no padrão NIST foi significativamente menor (p<0,05) que o valor esperado. Os alimentos analisados tiveram c.v. dentro do limite estabelecido (10%). No padrão AIN93G e no farelo de aveia não foi observada interferência da matriz .O conteúdo de magnésio total encontrado nas marcas de água mineral analisadas variou de 0,5 a 1,2 mgMg/100g. Apesar dos valores estarem acima do encontrado, mesmo assim a água não contribui com o consumo dietético de magnésio acima de 7% da EAR, considerando a ingestão de 2 litro/d de água. Dentre os alimentos submetidos à cocção, o quiabo, o espinafre, a mandioca e o feijão tiveram diferenças significativas (p<0,05) entre as formas cruas e processadas. As marcas de farinha de milho, farelo de aveia, pão integral e achocolatado em pó analisadas estão diferentes dos valores esperados, provavelmente devido à diferente origem dos alimentos encontrados nas tabelas de composição utilizadas. / The study evaluated the magnesium comsuption in body building\'s diet (n = 15) according to the new Dietary Reference Intakes (IDRs). Magnesium\'s food sources also were identified of the studied group and in marathon runners\' diet of the same age, so they could be reproduced and analyzed in its total magnesium content. This way, the obtained results in laboratory could becompared with the ones found in food composition tables, also conducting the validity of total magnesium\'s determination methodology . The magnesium dietary consumption (average±standard deviation) was 323±115 mgMg/d and 115±26 mgMg/1000kcal in the the 19-30 year-old group and 345±110 mgMg/d and 110±18 mgMg/1000kcal in the 31 to 50 year-old group, without significant differences among the studied groups. In this scenario, 5 body building athletes had the minimum probability of 70% of adequate magnesium\'s usual ingestion, while 6 showed at least 70% of minimum probability of inadequate magnesium\'s usual ingestion. Should be done a better dietary contribution of the mineral in question, emphasizing a larger food consumption with higher magnesium content. The main boby builders\' Mg food sources were banana, steak, cooked potato, cooked spinach, bean, semi-skimmed milk and oat flakes. Also, for the marathon runners these were represented by banana, com flour, oat bran, bean, steak, cooked fish, okra, chocolate powder, whole-meal bread and cassava. The calibration curve found for magnesium was linear (r = 0,9999), presenting DL and QL O, 15±0, 17 and 0,48±0,55 mgMg/mL In total magnesium determination the certified reference material (NIST) and secundary reference material (AIN93G) presented a variation coefficient (c.v.) of 4,4 and 3,2%, respectively. Even so, the obtained concentration in the NIST reference material was significantly smaller (p <0,05) than the expected value. The analyzed foods had c.v. below the established limit (10%). In the AIN93G reference material and in the oat bran no matrix\'s interference were observed . The total magnesium content found in the analyzed brands of mineral water ranged from 0,5 to 1,2 mgMg/100g. In spite the values above the expected ones, the water doesn\'t contribute with the dietary consumption of magnesium above 7% of EAR, considering the ingestion of 2 liter/d of water. Among the foods submitted to cooking process, okra, spinach, cassava and bean had significant differences (p <0,05) among raw and processed forms. The corn flour, oat bran, whole-meal bread and chocolate powder\'s brands analyzed are different from the expected values, probably due to the different origin of the foods found in the used composition tables.

No description available.

Type 2 diabetes mellitus (DM) is a progressive disease characterised by hyperglycaemia caused by defects in insulin secretion and insulin action. In early stages of type 2 DM, dietary and lifestyle changes are often sufficient to control blood glucose levels. However, over time, many patients experience β cell dysfunction and require insulin therapy, either alone or in combination with oral agents. There are guidelines available to structure the management of this disease state, including both the use of oral hypoglycaemic agents and or insulin. Besides health complications, there are economic burdens associated with the management of type 2 diabetes mellitus. The aim of this study was to determine the management of type 2 DM in a South African sample group of patients drawn from a large medical aid database. The objectives of the study were: to establish the prevalence of type 2 DM relative to age, examine the nature of chronic comorbid disease states, establish trends in the prescribing of insulin relative to other oral hypoglycaemic agents, investigate cost implications, and determine trends in the use of blood and urine monitoring materials by patients. The study was quantitative and retrospective and descriptive statistics were used in the analysis. DM was found to be most prevalent amongst patients between 50 and 59 years old. Results also demonstrated that 83% of DM patients also suffered from other chronic comorbid diseases, with cardiovascular diseases, especially hypertension and hypercholesterolaemia being the most prominent. This study also revealed that DM is predominantly managed with oral hypoglycaemic agents. Changes in drug prescribing, for chronic disease states such as DM may have medical, social and economic implications both for individual patients and for society and it is envisaged that the results of this study can be used to influence future management of DM. Keywords: Pharmacoepidemiology, management, type 2 diabetes mellitus

M.Sc. (Biochemistry) / A rich diversity of medicinal plants is found in Southern Africa and approximately 80% of the population still relies on medicinal plants to fulfil its primary health care needs. Many of these medicinal plants are used to treat ailments such as burns, sores, urinary tract infections, colds, flu, rheumatism, gout, cancer, hypertension, diabetes, human immunodeficiency virus infections and acquired immunodeficiency syndrome. An example of such a plant is Hypoxis hemerocallidea (Fisch & CA Mey), formerly known as Hypoxis rooperi and popularly known as the African potato, from the Hypoxidaceae family. This plant is found across five of the South African provinces and corm extracts are reported to contain bioactive compounds that account for the plant’s medicinal and therapeutic properties. This study was conducted to investigate the anti-oesophageal cancer and antimicrobial potential of H. hemerocallidea. In cancer patients, the currently used cancer treatments such as radiotherapy and chemotherapy are ineffective in decreasing disease progression, prolonging survival, providing cure and are associated with side-effects such as cytotoxicity to normal body cells and tumour non-specificity. Therefore, current cancer research is aiming at searching for novel plant-based anticancer compounds that can be used for the development and manufacturing of cancer treatment drugs that will have less side-effects and less toxicity towards the normal human body cells, and ultimately provide cure for cancer. In addition to cancer, infectious diseases still contribute to most premature deaths worldwide and are now becoming more difficult to treat due to multidrug resistance developed by pathogens against many of the currently used antibiotics. This multidrug resistance of human pathogens to antibiotics has led to a search for new antimicrobial compounds from plants sources, for use in the production of new affordable antibiotic drugs to effectively treat infections without posing any unwanted toxicity and harm towards the human body. An oesophageal SNO cancer cell line was treated with H. hemerocallidea extracts and the effect of the extracts on the cancer cells were investigated with cell viability assays (trypan blue dye exclusion and AlamarBlue® viability assays), light microscopy and flow cytometrical analysis (forward and side scatter analysis). The plant extracts were also tested for antimicrobial activities against various microorganisms - Gram-positive and Gram-negative bacteria, yeast and fungi cultures by means of thin layer chromatographic bioautography (TLC-DB), microdilution assays and the BacTiter-GloTM assay. Antimicrobial compounds were then putatively identified and characterised using gas chromatography-mass spectrometry (GC-MS). No morphological changes were observed in the SNO cells and significant cell death did not occur following treatment with either water or ethanolic H. hemerocallidea extracts from fresh or dried corms or leaves. The ethanolic leaf extracts did not show any significant inhibition against any of the microorganisms tested in contrast to the ethanolic extracts from the corms, which showed microbial growth inhibition against Gram-positive bacteria and fungi and partial inhibition of the Gram-negative bacteria. The bioactive compounds responsible for the antibacterial and antifungal activities were identified as levoglucosan (as the major antimicrobial compound), pyrocatechol and hexahydro-3-(2-methylpropyl)-pyrrolo[1,2-α]pyrazine-1,4-dione. These results show that H. hemerocallidea plant extracts possessed no anticancer effects towards the SNO cell line. In addition, the corm extracts of H. hemerocallidea contain a levoglucosan compound, which may work synergistically with other antimicrobial compounds to exert antimicrobial properties. With more research, the antimicrobial compounds in H. hemerocallidea may hold promise for possible candidates for use in the development of antibiotic or antiseptic products (for example, topical creams and lozenges) to be used in the treatment of skin and soft tissue infections caused by bacterial and fungal infections.

No description available.