Thesis (Ph. D.)--University of Wisconsin--Madison, 1930. / Typescript. eContent provider-neutral record in process. Description based on print version record. Annotated bibliography: leaves 44-55.

Thesis (M.S.)--University of North Carolina at Greensboro, 2006. / Title from PDF title page screen. Advisor: Gregory Raner; submitted to the Dept. of Chemistry. Includes bibliographical references (p. 109-116).

Thesis (M.S.)--University of North Carolina at Greensboro, 2007. / Title from PDF title page screen. Advisor: Jason Reddick; submitted to the Dept. of Chemistry. Includes bibliographical references (p. 41-46).

Thesis(M.S.)--Auburn University, 2006. / Abstract. Vita. Includes bibliographic references.

Thesis (Ph. D.)--University of Missouri-Columbia, 2000. / Typescript. Vita. Includes bibliographical references (leaves 230-254). Also available on the Internet.

Thesis (Ph. D.)--University of Missouri-Columbia, 2000. / Typescript. Vita. Includes bibliographical references (leaves 230-254). Also available on the Internet.

Made available in DSpace on 2014-06-11T19:31:03Z (GMT). No. of bitstreams: 0 Previous issue date: 2013-09-27Bitstream added on 2014-06-13T18:41:30Z : No. of bitstreams: 1 monteiro_ba_dr_arafcf_parcial.pdf: 206336 bytes, checksum: 50ba616712e67ae80c50a03beaa72edf (MD5) Bitstreams deleted on 2015-06-22T12:53:48Z: monteiro_ba_dr_arafcf_parcial.pdf,. Added 1 bitstream(s) on 2015-06-22T12:54:45Z : No. of bitstreams: 1 000726261_20151010.pdf: 119982 bytes, checksum: 44d8f0a3e6734ccdc79da6e02de2412f (MD5) Bitstreams deleted on 2015-10-13T15:52:26Z: 000726261_20151010.pdf,. Added 1 bitstream(s) on 2015-10-13T15:53:12Z : No. of bitstreams: 1 000726261.pdf: 639151 bytes, checksum: 797e7a318d2a8baa4da1def0af8187f6 (MD5) / A população de idosos vem aumentando no Brasil e no mundo, indicando a necessidade de rever os cuidados com a saúde em busca de melhor qualidade de vida. Alterações da imunidade relacionadas à idade podem ser particularmente prevenidas ou retardadas por intervenção dietética. Este trabalho teve como objetivo avaliar o estilo de vida, os hábitos alimentares, o estado nutricional e de saúde, e o efeito do consumo de bebida de frutas contendo Echinacea na saúde de idosos. 60 idosos participantes da Universidade Aberta da Terceira Idade (UNATI) de Franca, SP, responderam questionários sobre características sócio-econômicas, cuidados de saúde, hábitos alimentares e estilo de vida, e passaram por avaliação antropométrica e exames laboratoriais. O grupo avaliado apresentou maioria de mulheres (85%), indivíduos com idade entre 60-69 anos (60%), com estudo até ensino médio (60%), aposentados (65%), com renda de até 5 salários mínimos (73,4%). A maioria dos idosos fazia acompanhamento médico (65%) e uso contínuo de medicamento (78,3%), tendo relatado estar com a pressão arterial controlada (80%) e não fumar (100%). 71,7% acreditavam que sua alimentação era saudável, 97% faziam as refeições em casa, 85% escolhiam e preparavam seus alimentos, 65% faziam 5-6 refeições por dia, 63% bebiam menos de 1L água/dia. 90% relataram ter bom funcionamento do intestino e 43,3% realizavam atividade física regularmente. Apenas 13,3% faziam reposição hormonal, 18,3% consumiam suplemento alimentar e 21,7% ingeriam bebida alcoólica. Os participantes apresentaram índice de massa corpórea (IMC) 27,5±4,5Kg/m², com prevalência em excesso de peso e eutróficos, cujos valores reduziram com a idade. Os valores de circunferência da panturrilha (CP) (36,3±3,8cm), circunferência do braço (CB) (31,4±4,1cm) e dobra cutêna triciptal (DCT) (20,6±7,5mm)... / The elderly population is increasing in Brazil and all over the world, highlighting the need to review health care practices in order to achieve a better quality of life. Immunity alterations that are age-related may be particularly prevented or delayed through dietary intervention. This study aimed at evaluating the lifestyle, eating habits, nutritional status and health and the effect of consumption of fruit drink containing Echinacea on elderly health. Sixty elderly, participants of the group of the Open University for Senior Citizens (UNATI), from UNESP at Franca, São Paulo, answered questions about socio-economic issues, health care, food consumption habits and lifestyle, and after, they were submitted to anthropometric and laboratory tests. Within the group that was evaluated had most women (85%), aged between 60-69 years old (60%), up to high school (60%), retired (65%), income up to 5 minimum wages (73.4%). Most seniors were under medical care (65%) and on medication (78.3%). The majority also reported having blood pressure under control (80%) and being non smokers (100%). About 71.7% of the participants believed their diet to be healthy, 97% had their meals at home, 85% chose and prepared their own food, 65% had 5-6 meals/day, 63% drank 1L of water/day. 90% reported having normal bowel function and 43.3% practice regular physical activity. Only 13.3% were doing hormone replacement therapy, 18.3% took dietary supplements and 21.7% drank alcoholic drinks. The participants presented BMI of 27.49±4.5kg/m², with prevalence of overweight and eutrophy, and these values decreased with age. Calf circumference (CC) (36.27±3.84cm), arm circumference (AC) (31.39±4.08cm) and triceps skinfolds (TS) (20.58±7.54mm) values were adequate in most cases... (Complete abstract click electronic access below)

Orientador: Magali Monteiro da Silva / Banca: Flávia Queiroga Aranha de Almeida / Banca: Anderson Marliére Navarro / Banca: Renata Maria Galvão de Campos Cintra / Banca: Cléria Maria Lobo Bittar / Resumo: A população de idosos vem aumentando no Brasil e no mundo, indicando a necessidade de rever os cuidados com a saúde em busca de melhor qualidade de vida. Alterações da imunidade relacionadas à idade podem ser particularmente prevenidas ou retardadas por intervenção dietética. Este trabalho teve como objetivo avaliar o estilo de vida, os hábitos alimentares, o estado nutricional e de saúde, e o efeito do consumo de bebida de frutas contendo Echinacea na saúde de idosos. 60 idosos participantes da Universidade Aberta da Terceira Idade (UNATI) de Franca, SP, responderam questionários sobre características sócio-econômicas, cuidados de saúde, hábitos alimentares e estilo de vida, e passaram por avaliação antropométrica e exames laboratoriais. O grupo avaliado apresentou maioria de mulheres (85%), indivíduos com idade entre 60-69 anos (60%), com estudo até ensino médio (60%), aposentados (65%), com renda de até 5 salários mínimos (73,4%). A maioria dos idosos fazia acompanhamento médico (65%) e uso contínuo de medicamento (78,3%), tendo relatado estar com a pressão arterial controlada (80%) e não fumar (100%). 71,7% acreditavam que sua alimentação era saudável, 97% faziam as refeições em casa, 85% escolhiam e preparavam seus alimentos, 65% faziam 5-6 refeições por dia, 63% bebiam menos de 1L água/dia. 90% relataram ter bom funcionamento do intestino e 43,3% realizavam atividade física regularmente. Apenas 13,3% faziam reposição hormonal, 18,3% consumiam suplemento alimentar e 21,7% ingeriam bebida alcoólica. Os participantes apresentaram índice de massa corpórea (IMC) 27,5±4,5Kg/m², com prevalência em excesso de peso e eutróficos, cujos valores reduziram com a idade. Os valores de circunferência da panturrilha (CP) (36,3±3,8cm), circunferência do braço (CB) (31,4±4,1cm) e dobra cutêna triciptal (DCT) (20,6±7,5mm)... (Resumo completo, clicar acesso eletrônico abaixo) / Abstract: The elderly population is increasing in Brazil and all over the world, highlighting the need to review health care practices in order to achieve a better quality of life. Immunity alterations that are age-related may be particularly prevented or delayed through dietary intervention. This study aimed at evaluating the lifestyle, eating habits, nutritional status and health and the effect of consumption of fruit drink containing Echinacea on elderly health. Sixty elderly, participants of the group of the Open University for Senior Citizens (UNATI), from UNESP at Franca, São Paulo, answered questions about socio-economic issues, health care, food consumption habits and lifestyle, and after, they were submitted to anthropometric and laboratory tests. Within the group that was evaluated had most women (85%), aged between 60-69 years old (60%), up to high school (60%), retired (65%), income up to 5 minimum wages (73.4%). Most seniors were under medical care (65%) and on medication (78.3%). The majority also reported having blood pressure under control (80%) and being non smokers (100%). About 71.7% of the participants believed their diet to be healthy, 97% had their meals at home, 85% chose and prepared their own food, 65% had 5-6 meals/day, 63% drank 1L of water/day. 90% reported having normal bowel function and 43.3% practice regular physical activity. Only 13.3% were doing hormone replacement therapy, 18.3% took dietary supplements and 21.7% drank alcoholic drinks. The participants presented BMI of 27.49±4.5kg/m², with prevalence of overweight and eutrophy, and these values decreased with age. Calf circumference (CC) (36.27±3.84cm), arm circumference (AC) (31.39±4.08cm) and triceps skinfolds (TS) (20.58±7.54mm) values were adequate in most cases... (Complete abstract click electronic access below) / Doutor

No description available.

Indiana University-Purdue University Indianapolis (IUPUI) / Polyacetylenic natural products, compounds containing multiple carbon-carbon triple bonds, have been found in a large collection of organisms. Radiochemical tracer studies have indicated that these bioactive metabolites are synthesized from fatty acid precursors through a series of uncharacterized desaturation and acetylenation steps. To date, there are three main pathways believed to be involved in acetylenic natural product biosynthesis. However, it is apparent that the crepenynic acid pathway is the origin of a vast majority of the known plant and fungal acetylenic products. This investigation provides concrete evidence that the polyacetylenic natural products found in the fungus Fistulina hepatica and the medicinal plant species Echinacea purpurea are biosynthesized from crepenynic acid. Through heterologous expression in Yarrowia lipolytica, two acetylenases capable of producing crepenynic acid were identified from E. purpurea. Furthermore, heterologous expression of two diverged desaturases isolated from F. hepatica, uncovered a ∆12-acetylenase and the first multifunctional enzyme capable of ∆14-/∆16- desaturation and ∆14-acetylenation.