Diss. (sammanfattning) Stockholm : Karol. inst., 2003. / Härtill 5 uppsatser.

Diss. (sammanfattning) Linköping : Linköpings universitet, 2004. / Härtill 4 uppsatser.

Thesis (M.P.H.)--University of Texas Health Science Center at Houston, School of Public Health, 2008. / Source: Masters Abstracts International, Volume: 46-04, page: 2059. Adviser: George L. Delclos. Includes bibliographical references.

Thesis--University of Oklahoma. / Bibliography: leaves 36-37.

Pašáková, N. Convergence of US GAAP and IFRS in the reporting of operating lease on the side of lessor. Diploma thesis. Brno: Mendel university in Brno, 2014. The diploma thesis is focused on the evaluation of potential impacts of the proposed change in the operating lease in accordance with international ac-counting standards compared with the currently applicable standard from the point of view of the lessor. The thesis is divided into two sections: theoretical and practical. The theoretical section deals with the analysis of the current ap-plicable standard IAS 17 and proposed procedures exposure draft ED/2010/9 and re-exposure draft ED/2013/6. The practical section shows the impact on the statements of the lessor and the indicators of financial analysis.

Conselho Nacional de Desenvolvimento Científico e Tecnológico / Paints occupational exposure is an important health problem due to the wide variety of chemicals and xenobiotics present in their constitution. Organic solvents and heavy metals are among the main chemical constituents of paints. In the view of the variety of substances found in paints, can be noted that painters are simultaneously exposed to various xenobiotics, suggesting a case of co-exposure or exposure mixed. Biological monitoring is an essential tool for assessing the risk to health and occupational health practices. Moreover, it is known that there is a close relationship between the xenobiotics constituents of paints and oxidative stress, such as toxicological mechanism. In this study was evaluated oxidative damage by quantification of blood biomarkers of oxidative stress such as malondialdehyde (MDA), reduced glutathione (GSH), δ-aminolevulinate dehydratase enzyme (ALA-D), superoxide dismutase (SOD) and catalase (CAT ), in individuals occupationally exposed to paints (n = 48) and non-exposed subjects (n = 30). Biological monitoring of toluene was performed by quantification of different biomarkers of exposure, urinary hippuric acid and ortho-cresol, and blood toluene. For xylene, styrene, ethylbenzene and lead were quantified urinary levels of methylhippuric acid, mandelic acid, phenylglyoxylic acid and blood lead, respectively. Despite all IBEs were below the biological limit exposure (BEL), significant changes in oxidative stress biomarkers were found in exposed group. Plasma levels of MDA and blood antioxidant enzymes (SOD and CAT) had shown increased in the group of painters when compared with non-exposed group; this increase was accompanied by GSH levels depletion and enzyme ALA-D inhibition. It was also observed several correlations between the oxidative stress biomarkers and biomarkers of exposure to xenobiotics present in paints. By statistical tests were evaluated which of the paints constituents played the greatest influence on changes in oxidative stress biomarkers, in this case of co-exposure. Among the exposure biomarkers tested, blood toluene was suggested as the main responsible for increased lipid peroxidation; in addition, it was appointed as a new and important inhibitor of the enzyme ALA-D. Thus, it is suggested that a joint evaluation of biomarkers of exposure and oxidative stress biomarkers might be useful to ensure, in longterm, the worker s health. / A exposição ocupacional a tintas representa um importante problema de saúde devido à ampla variedade de substâncias químicas e xenobióticos presentes na sua constituição. Solventes orgânicos e metais pesados encontram-se entre os principais compostos químicos constituintes das tintas. Tendo em vista a variedade de substâncias presentes na composição das tintas, pode-se constatar que pintores encontram-se simultaneamente expostos a diferentes xenobióticos, caracterizando um processo de coexposição ou exposição mista. A monitorização biológica é uma ferramenta essencial para a avaliação do risco à saúde e práticas de saúde ocupacional. Por outro lado, sabe-se que existe uma estreita relação entre os xenobióticos constituintes de tintas e o estresse oxidativo, como mecanismo toxicológico. Neste estudo foi avaliado o dano oxidativo, através da quantificação de biomarcadores sanguíneos do estresse oxidativo, como alondialdeído (MDA), glutationa reduzida (GSH), enzima δ-aminolevulinato desidratase (ALA-D), superóxido dismutase (SOD) e catalase (CAT); em indivíduos expostos (n=48) e não expostos (n=30) ocupacionalmente a tintas. A monitorização biológica do tolueno foi realizada através da quantificação dos diferentes biomarcadores de exposição, ácido hipúrico e orto-cresol urinários, e tolueno sanguíneo. Para xileno, estireno, etilbenzeno e chumbo foram quantificados os níveis urinários dos ácidos metil-hipúrico, mandélico, fenilglioxílico, e chumbo sanguíneo, respectivamente. Apesar de todos os IBEs se encontrarem abaixo dos índices biológicos máximos permitidos (IBMP), alterações significativas nos biomarcadores do estresse oxidativo foram encontradas no grupo de expostos. Os níveis plasmáticos de MDA e das enzimas sangüíneas antioxidantes (SOD e CAT) se mostraram aumentados no grupo de pintores quando comparados com o grupo não exposto; esse aumento foi acompanhado pela depleção nos níveis de GSH e inibição da enzima ALA-D. Foram observadas ainda várias correlações entre os biomarcadores do estresse oxidativo e biomarcadores de exposição aos xenobióticos presentes nas tintas. Através de testes estatísticos foram avaliados quais dos constituintes das tintas desempenhavam maior influência sobre as alterações nos biomarcadores de estresse oxidativo, nesse caso de co-exposição. Dentre os biomarcadores de exposição analisados, o tolueno sanguíneo foi sugerido como o principal responsável pelo aumento da peroxidação lipídica; além de ser apontado como um novo e importante inibidor da enzima ALA-D. Dessa forma, sugere-se que a avaliação conjunta de biomarcadores de exposição e biomarcadores do estresse oxidativo possa ser útil para assegurar, em longo, prazo a saúde do trabalhador.

Hintergrund: In der Kognitiven Verhaltenstherapie (KVT) der Panikstörung mit Agoraphobie (PD/AG) werden häufig Körperübungen zur Symptomprovokation (interozeptive Exposition) eingesetzt, jedoch liegen kaum systematische, empirische Untersuchungen zu Wirkung und Wirkweise dieser Übungen vor. Ziel der vorliegenden Studie war die Charakterisierung individueller Reaktionen auf interozeptive Übungen sowie die mit der Wiederholung der Übungen verbundenen Veränderungen dieser Reaktionen. Patienten und Methoden: Selbstberichtdaten zu ausgelösten Körpersymptomen sowie Symptom- und Angststärken von 301 Patienten mit PD/AG, die verschiedene interozeptive Übungen durchführten, wurden ausgewertet. Die Durchführung der interozeptiven Exposition erfolgte im Rahmen einer manualisierten KVT des Psychotherapieverbundes «Panik-Netz». Ergebnisse: Interozeptive Exposition löste Körpersymptome und damit verbunden Angst aus. Am häufigsten wurden vestibuläre, respiratorische und kardiovaskuläre Symptome ausgelöst. Die stärkste Symptomausprägung verbunden mit der stärksten Angst erzeugten die Übungen «Drehen», «Hyperventilieren» und «Strohhalmatmung». Übungswiederholung bewirkte eine Reduktion der Symptom- und Angststärken, insbesondere die Übungen «Drehen», «Strohhalmatmung» und «Hyperventilieren». Diskussion und Schlussfolgerungen: Interozeptive Exposition ist gut geeignet zur Auslösung von Körpersymptomen und zur Reduktion der damit verbundenen Symptom- und Angststärke, insbesondere über die Übungen «Drehen», «Hyperventilieren» und «Strohhalmatmung». Zur größeren Angst- und Symptomstärkenreduktion empfiehlt sich eine hohe Wiederholungsrate. Die Relevanz respiratorischer, vestibulärer und kardiovaskulärer Symptome für den Behandlungserfolg sollte weiterführend untersucht werden. / Background: Although interoceptive exposure is a frequent component of cognitive-behavioral therapies (CBT) in panic disorder with agoraphobia, there is a lack of evidence investigating the effect of this treatment component and its underlying mechanisms of change. The present study aimed at characterizing individual responses to interoceptive exposure and response changes after repeated exposure. Patients and Methods: Under the national research initiative ‘Panic Net’, self-report data were analyzed including bodily symptoms, symptom intensity and experienced anxiety during interoceptive exposure of 301 PD/AG patients who participated in a manualized CBT trial. Results: Interoceptive exposure induced bodily symptoms and anxiety. Respiratory, vestibular and cardiovascular symptoms were most frequently reported. Spinning, breathing through a straw and hyperventilation produced most intense symptom reports and anxiety ratings. Repeating the interoceptive exposure reliably reduced reported symptom intensity and anxiety ratings particularly after spinning, breathing through a straw and hyperventilation. Discussion and Conclusions: In PD/AG patients, interoceptive exposure induces bodily symptoms and reduces reported symptom intensity and anxiety, particularly through spinning, hyperventilation and breathing through a straw. Repeated rehearsal is encouraged given that larger reduction of anxiety and symptom reports were associated with more training. Further research is needed to assess the relevance of respiratory, vestibular and cardiovascular symptoms for CBT treatment.

Eine häufigere bloße Darbietung eines Objekts führt bis zu einem bestimmten Punkt zu einer Einstellungsverbesserung. Dieser Zusammenhang wird im Mere-Exposure-Effekt postuliert. Obwohl sich eine Verknüpfung von Häufigkeit und Dauer vermuten lässt, konnte ein ähnlicher Effekt für die Präsentationsdauer nicht gefunden werden. Bisherige Ergebnisse deuteten auf einen negativen Effekt bei steigender Dauer hin. Asymmetrische Wirkungen von Häufigkeit und Dauer zeigten sich ebenfalls bei gedächtnisbasierten Urteilen. Es stellte sich heraus, dass Aufmerksamkeit eine wichtige Rolle bei Dauereffekten spielt. Die vorliegende Studie untersucht darauf aufbauend den Einfluss der Dauer im Mere-Exposure-Effekt unter aufrechterhaltender Aufmerksamkeit. Mit einem Online-Experiment wurden Bewertungen zu Bildern erfasst, welche zuvor in variierenden Häufigkeiten und Zeiten präsentiert wurden. Es konnten N=97 Personen (Anteil weiblich=83,5%, Alter M=25 Jahre) in die finale Stichprobe, aufgeteilt in vier Untersuchungsgruppen, einbezogen werden. Die Gruppen unterschieden sich zum einen hinsichtlich des präsentierten Materials (bunt oder schwarz-weiß) und zum anderen hinsichtlich ihrer körperlichen Aktivität während der Darbietung. Die Ergebnisse zeigen, dass auch längere Präsentationszeiten in Interaktion mit hoher Aufmerksamkeit Einstellungsverbesserungen bewirken können. Somit kann geschlussfolgert werden, dass die Gesamtpräsentationsdauer eines Objektes ebenfalls relevant im Mere-Exposure-Effekt sein kann, sofern die Aufmerksamkeit aufrechterhalten wird.

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Cirka 3 % av kvinnor som fött barn uppfyller DSM-5 diagnostiska kriterier för PTSD, och minst en tredjedel uppger att de upplevt förlossningen som traumatisk. Prolonged exposure (PE) är en evidensbaserad traumafokuserad kognitiv beteendeterapi och en effektiv behandling för att reducera PTSD-symptom över en varierad traumatiserad population. Terapeutperspektivet gällande behandling av patienter med förlossningstrauma (PTSD-FC) är sällsynt i forskningen. Övergripande syfte var att belysa KBT-terapeuters perspektiv av att arbeta med behandlingsmetoden PE vid PTSD-FC med frågeställningar som; Vad kan vara utmärkande med att behandla patienter med PTSD-FC? Vilka kliniska erfarenheter har terapeuterna av att tillämpa PE-manualen med aktuell patientgrupp? Studien har en kvalitativ ansats. Semistrukturerade intervjuer har genomförts med åtta terapeuter. Bearbetning av data utgick från reflexiv tematisk analys. I resultatet genererades tre teman med subteman utifrån terapeuternas erfarenheter. ”Ett förlossningstrauma har vissa utmärkande drag”, ”Betydelsen av traumat”  samt ”PE-manualens möjligheter”. Terapeuterna ansåg att PE är en flexibel, hjälpsam och effektiv traumabehandling som fungerar väl med patientgruppen. Patienterna var vanligtvis motiverade och fullföljer terapin i hög grad. Tillgången till adekvat vård var god inom terapeuternas egna verksamheter medan en problematisk bild kom fram avseende andra vårdgivare. Utmaningar och möjligheter diskuteras angående det terapeutiska arbetet med patientgruppen. Kliniska implikationer som tas upp är till exempel behovet av ökade terapeutiska resurser inom kvinnosjukvården för adekvat bedömning och behandling vid PTSD-FC, där fördelen är samverkan mellan olika professioner. / Approximately 3% of women who have given birth, meet the DSM-5 diagnostic criteria for PTSD, and at least a third say they experienced childbirth as traumatic. Prolonged exposure (PE) is an evidence-based trauma-focused cognitive behavioral therapy and an effective treatment for reducing PTSD symptoms across a diverse traumatized population. The therapists’ perspective regarding the treatment of patients’ with postpartum trauma (PTSD-FC) is rare in research. The overall aim was to highlight CBT therapists' perspectives of working with the treatment method PE at PTSD-FC with questions such as; What may be distinctive about treating patients’ with PTSD-FC? What clinical experience do therapists’ have of applying the PE manual with the current patient group? The study has a qualitative approach. Semi-structured interviews have been conducted with eight therapists’. Processing of the data was based on reflexive thematic analysis. In the results, based on the therapists' experiences, three themes with subthemes were generated. “A postpartum trauma has some distinguishing features”, “The meaning of the trauma” and “The possibilities of the PE manual”. The therapists’ considered PE to be a flexible, helpful, and effective trauma treatment that works well with the patient group. The patients’ were usually motivated and completed the therapy to a high degree. Access to adequate care was good within the therapists' own settings, while a problematic picture emerged regarding other caregivers. Challenges and opportunities are discussed regarding the therapeutic work with the patient group. Clinical implications addressed are for example the need for increased therapeutic resources in women's healthcare for adequate assessment and treatment for PTSD-FC, where the advantage is collaboration between different professions. / <p>Linköpings universitet | Institutionen för beteendevetenskap och lärande Psykoterapeutexamensuppsats/magisteruppsats/uppsats på avancerad nivå, 15 hp | Psykoterapeutprogrammet (KBT) Höstterminen 2022 </p>