Diss. -- Helsingin yliopisto. / Includes bibliographical references. Myös verkkojulkaisuna. Also available on the World Wide Web.

Thesis (Ph.D.)--Victoria University (Melbourne, Vic.), 2009.

Thesis (M.S.) University of Missouri-Columbia, 2006. / The entire dissertation/thesis text is included in the research.pdf file; the official abstract appears in the short.pdf file (which also appears in the research.pdf); a non-technical general description, or public abstract, appears in the public.pdf file. Title from title screen of research.pdf file (viewed on August 21, 2007) Includes bibliographical references.

Thesis (Ph.D.)--University of Delaware, 2006. / Principal faculty advisor: Arwen P. Mohun, Dept. of History. Includes bibliographical references.

Thesis (M.S.)--West Virginia University, 2007. / Title from document title page. Document formatted into pages; contains xi, 87 p. : ill. Vita. Includes abstract. Includes bibliographical references.

Thesis (Ph. D.)--University of Missouri-Columbia, 1999. / Typescript. Vita. Includes bibliographical references (leaves 99-102). Also available on the Internet.

Submitted by Luciana Cristina Leite (luciana.leite@etec.sp.gov.br) on 2018-06-06T19:15:04Z No. of bitstreams: 1 Leite_LC_Specialty Foods_PGAD_Unesp.pdf: 2399189 bytes, checksum: 7231363a289cebcb70c13992708dee26 (MD5) / Approved for entry into archive by Eliana Katia Pupim (katiapupim@tupa.unesp.br) on 2018-06-11T14:29:15Z (GMT) No. of bitstreams: 1 leite_lc_me_tupa.pdf: 2209116 bytes, checksum: c93aeabee3cd99bbb84447d9f03ae85f (MD5) / Made available in DSpace on 2018-06-11T14:29:15Z (GMT). No. of bitstreams: 1 leite_lc_me_tupa.pdf: 2209116 bytes, checksum: c93aeabee3cd99bbb84447d9f03ae85f (MD5) Previous issue date: 2018-02-23 / O segmento de produtos Specialty Foods vem ganhando reconhecimento nos mercados globais, por apresentar atributos cada vez mais demandados pelos consumidores. Nessa perspectiva, esse segmento vem se caracterizando como uma oportunidade de atuação de organizações produtoras brasileiras que desejam acessar mercados internacionais, tendo em vista o potencial do Brasil na produção e exportação de alimentos, e as ações da Agência Brasileira de Promoção de Exportações e Investimentos (Apex-Brasil), no desenvolvimento dos projetos setoriais para promoção internacional de empresas exportadoras. Nesse aspecto, e levando-se em conta as peculiaridades de se acessar os mercados internacionais, o presente trabalho teve por objetivo analisar o processo de internacionalização das organizações e instituições vinculadas aos projetos setoriais da Apex-Brasil na categoria de produtos Specialty Foods. Para tanto, foi utilizada uma pesquisa qualitativa, cujos objetivos foram descritivos. Os procedimentos metodológicos envolveram o desenvolvimento teórico abordando questões ligadas à internacionalização de empresas, do marketing internacional e do papel da esfera pública nesse processo; a pesquisa de campo, com profissionais da instituição Apex-Brasil e uma Associação, e estudos de casos com cinco empresas do estado de São Paulo. Os resultados indicaram que a estratégia utilizada pelas empresas tem sido o modelo de exportação direta, justificada pela vantagem de controle sobre as atividades de exportação. Identificou-se que o ambiente de marketing tem forte impacto no planejamento estratégico das empresas, desafiando-as na adaptação e inovação de estratégias para serem mais competitivas nos mercados, tendo como impulsionador a força cultural. Em relação a barreiras de acesso, as empresas estão sujeitas às barreiras sanitárias e fitossanitárias, devido à categoria de produtos alimentícios e também às barreiras técnicas e ambientais. Em relação às ações da Apex-Brasil e da Associação Setorial ABBA, constatou-se as ações de promoção comercial implicaram em aperfeiçoamentos relevantes para as empresas em seu processo internacionalização, assim como ampliaram as oportunidades de atuação no mercado dos Estados Unidos, em termos de Specialty Foods. Limitações da pesquisa, bem como as contribuições e sugestões de direcionamento de novas pesquisas, com o intuito de progredir nos estudos sobre agências de promoção comercial, no âmbito das empresas e das ações da Agência em diferentes mercados são apresentados nas considerações finais. / The Specialty Foods product segment has been gaining recognition in global markets because of the increasingly demanding attributes of consumers. In this perspective, this segment has been characterized as an opportunity for Brazilian producer organizations wishing to access international markets, in reason of Brazil's potential in the production and export of food, and the actions of the Brazilian Agency for the Promotion of Exports and Investments (Apex-Brasil), in the development of sectoral projects for the international promotion of export companies. In this regard, and taking into account the peculiarities of accessing international markets, the objective of this work was to analyze the internationalization organizations process and institutions linked to Apex-Brasil's sectorial projects in the category of Specialty Foods products. For that, a qualitative research was used, whose objectives were descriptive. The methodological procedures involved the theoretical development addressing issues related to the internationalization of companies, international marketing and the role of the public sphere in this process; the field research, with professionals from the Apex-Brazil institution and an Association, and case studies with five companies from the state of São Paulo. The results indicated that the strategy used by the companies has been the direct export model, justified by the advantage of control of the export activities. It was identified that the marketing environment has a strong impact on the strategic planning of the companies, challenging them in the adaptation and innovation of strategies to be more competitive in the markets, having as booster the cultural force. In relation to the access barriers, companies are subject to sanitary and phytosanitary barriers due to the category of food products as well as technical and environmental barriers. In relation to the actions of Apex-Brasil and the ABBA Sectorial Association, it was found that the commercial promotion actions implied in relevant improvements for the companies in their internationalization process, as well as expanded opportunities in the United States market in terms of Specialty Foods. Limitations of the research, as well as the contributions and suggestions for the direction of new research, in order to progress in the studies on commercial promotion agencies, within the scope of the companies and the actions of the Agency in different markets are presented in the final considerations.

Orientador: Ricardo Luiz Sapia de Campos / Banca: Auro Aparecido Mendes / Banca: Rafael Alves Orsi / Resumo: A pesquisa teve por objetivo entender e debater os espaços de comercialização dos produtos orgânicos como as feiras, as lojas especializadas, as cooperativas de consumo e os supermercados e as múltiplas influências de seus consumidores nas estratégias produtivas e de desenvolvimento de pequenos e médios produtores orgânicos do interior paulista. Em canais longos de comercialização como os supermercados as relações são distantes, individualizadas e mediadas pela obrigatoriedade do selo de certificação, por outra parte, em canais curtos como as feiras e as cooperativas de consumo o diálogo e as relações democráticas permitem compartilhar e difundir os valores de uma alimentação saudável e de qualidade, estabelecendo confiança por meio da proximidade. Em sua gênese a agricultura orgânica defende uma produção não somente livre do uso de agrotóxicos, mas um conjunto de práticas voltadas a preservação dos recursos naturais, ao respeito às demandas sociais e econômicas das comunidades locais, e ao cultivo de uma alimentação saudável e de qualidade que cumpra com a necessidade da segurança alimentar. A valorização desses produtos é projetada, portanto, por seus atributos subjetivos, trazendo à tona um processo em que as qualidades imateriais integram o valor econômico. Idealizada inicialmente para pequenas e médias propriedades, a agricultura orgânica começa a ser apropriada por impérios alimentares que se aproveitam desse mix de subjetividades na geração de mercadorias destinadas a ... (Resumo completo, clicar acesso eletrônico abaixo) / Resumen: La investigación tuve como objetivo entender y debatir los espacios de comercialización de los productos ecológicos como las ferias, las tiendas especializadas, las cooperativas de consumo y los supermercados y las diversas influencias de sus consumidores en las estrategias productivas y de desarrollo de pequeños y medianos productores ecológicos del interior paulista. En los canales largos de comercialización como los supermercados las relaciones son distantes, individualizadas y mediadas por la obligatoriedad del sello de certificación, por otra parte, en los canales cortos como las ferias y las cooperativas de consumo el dialogo y las relaciones democráticas permiten compartir y difundir los valores de una alimentación sana y de calidad, estableciendo confianza mediante la proximidad. En su génesis la agricultura ecológica defiende una producción no solo libre de los pesticidas, pero envuelta por un conjunto de prácticas volteadas a la preservación de los recursos naturales, al respeto a las demandas sociales y económicas de las comunidades locales, y al cultivo de una alimentación sana y de calidad que cumpla con la necesidad de la seguridad alimentaria. La valorización de esos productos es proyectada, por lo tanto, por sus atributos subjetivos, aportando un proceso en que las calidades inmateriales forman parte del valor económico. Inicialmente idealizada para pequeñas y mediadas fincas, la agricultura ecológica empieza a ser apropiada por imperios alimentarios que se ap... (Resumen completo clicar acceso eletrônico abajo) / Mestre

Orientador: Manoel Lima de Menezes / Banca: Valdecir Farias Ximenes / Banca: Eliane Maria Ravasi Stéfano Simionato / Banca: Juliana Cristina Bassan / Banca: Luiz Carlos da Silva Filho / O Programa de Pós Graduação em "Ciência e Tecnologia de Materiais" tem caráter institucional e integra as atividades de pesquisa em materiais de diversos campi / Resumo: As hortaliças não-convencionais como ora-pro-nóbis (Pereskia aculeata Mill.) e moringa (Moringa oleifera Lam.) são uma alternativa alimentar com excelente valor nutricional, de fácil cultivo e baixo custo. Têm sido descritas como importantes fontes de proteínas de composição equilibrada de aminoácidos, alto teor de fibras e de lipídios, principalmente ácidos graxos insaturados. Assim, este trabalho teve como objetivo a elaboração e caracterização das farinhas das folhas de Pereskia aculeata Mill. e Moringa oleifera Lam., além da avaliação sobre ratos Wistar de parâmetros bioquímicos e motilidade intestinal dos efeitos da administração destas farinhas. A caracterização química das farinhas foi feita por meio da determinação de umidade, cinzas, lipídios, composição de ácidos graxos, proteínas, aminograma, carboidratos, fibras, sódio, cálcio, e potássio. Os dados obtidos foram submetidos à análise de variância (ANOVA) complementada com o teste de Tukey. As farinhas estudadas apresentaram valores de umidade considerados seguros pela legislação brasileira. O alto teor de carboidratos das farinhas é indicativo de uma planta potencialmente energética. Verificou-se ainda que as farinhas apresentaram altos teores de proteína, fibras, cálcio e na composição de ácidos graxos, destacou-se o α-linolênico. Com relação aos estudos bioquímicos e antropométricos, observou-se que a utilização das farinhas melhorou o perfil lipídico, evitou ganho de peso e não apresentou efeitos adversos signif... (Resumo completo, clicar acesso eletrônico abaixo) / Abstract: Unconventional vegetables like ora-pro-nobis (Pereskia aculeata Mill.) and moringa (Moringa oleifera Lam.) are an alternative food with excellent nutritional value, easy to grow and low cost. They have been described as important sources of protein balanced amino acid composition, high fiber content and lipids, especially unsaturated fatty acids. Thus, this study aimed to the preparation and characterization of flour leaves of Pereskia aculeata Mill. Moringa oleifera Lam, apart from review of biochemical parameters of Wistar rats and intestinal motility effects of administration of these flour. The chemical characterization of flour was made by the moisture determination, ash, lipids, fatty acid composition, protein, aminogram, carbohydrates, fiber, sodium, calcium, and potassium. The data were submitted to analysis of variance (ANOVA) complemented by the Tukey test. Flours studied showed humidity values considered safe by Brazilian law. The high carbohydrate content of the flours is indicative of a potentially energy plant. It was also found that the meal had high levels of protein, fiber, calcium and fatty acid composition, the highlight was the α-linolenic. With regard to the anthropometric and biochemical studies it was observed that the use of flour has improved lipid profile avoided weight gain and has no significant adverse effects. The use of flours also positively influenced the intestinal motility. The results obtained in the analysis, one can explore the use of the... (Complete abstract click electronic access below) / Doutor

Dietary restriction (DR) is the only known nutritional manipulation that can increase both lifespan and healthspan in a variety of species. Underlying these increases are improvements in metabolic health and reductions in cancer incidence. Despite these physiological improvements, the regulation of skeletal muscle mass is extremely sensitive to alterations in nutrients [reviewed in (Sharples et al., 2015)] and as such has been reported to reduce regenerative potential and increase atrophy in skeletal muscle cells and myotubes. Interestingly, the activation of Sirtuin1 (SIRT1) has been reported during DR and its reduction abrogates lifespan extension. Importantly, SIRT1 activation via resveratrol treatment has been indicated to be important in the presence of inflammatory stress (TNF-α) (Saini et al., 2012). Resveratrol supplementation has also improved survival and regeneration of skeletal muscle cells as well in muscle cell remodelling following oxidative stress (Bosutti and Degens, 2015). We therefore sought to create an in-vitro physiological model of DR by mimicking levels of glucose in the circulation and interstitium in-vivo in response to DR (Chapter 3) as well as optimising the activation and inhibition of SIRT1 using resveratrol and SIRT1 inhibitor, EX-527 respectively (Chapter 4). With our ultimate aim to investigate the potential role and mechanisms of the activation/inhibition of SIRT1 in ameliorating the degenerative/atrophic effect of DR in both differentiating myoblasts (Chapter 5) and mature myotubes (Chapter 6). Indeed, in Chapter 3 we present two models of reduced glucose; one reduced (medium/ MED) and the other blocked (LOW) differentiation and myotube hypertrophy. The former represented circulatory glucose blood levels (MED 1.13 g/L or 6.25 mM) and the latter interstitial represented glucose levels (LOW 0.56 g/L or 3.12 mM) of rodents under DR. In Chapter 4 we also suggest that within the in vitro muscle cell model, activation/inhibition of SIRT1 phosphorylation (western blot analysis) was thought to be most effective at 10 μM of resveratrol and 100 nM of EX-527 respectively. In chapter 5, we observed that resveratrol treatment did not improve fusion when administered to differentiating myoblasts. Resveratrol did however evoke increases in myotube hypertrophy under normal glucose conditions. Importantly resveratrol enabled improved myotube hypertrophy over an acute 24 h period when administered to existing mature myotubes in low glucose environments. If this finding translates to whole organisms and human populations it could provide healthspan improvements via reductions in fragility associated with loss of muscle mass in individuals undergoing dietary restriction. After this 24 h period resveratrol was unable to reduce myotube atrophy and the myotubes continued to atrophy, suggestive of a need for repeated resveratrol treatment to enable continued protection against muscle atrophy under low glucose conditions. SIRT1 activation increased Myogenic regulatory factor 4 (MRF4) gene expression under LOW glucose conditions which was associated with the observed improvements in myotube size at 24 h. Whereas, SIRT1 activation via resveratrol treatment in normal glucose conditions modulated increased gene expression of Myosin heavy chain 7 (MYHC7) coding for the slow isoform while inhibition of SIRT1 (EX-527) lead to reductions in gene expression of MYHC 1, 2 and 4, coding for faster IIx, IIa, IIb isoforms respectively. Perhaps suggesting that elevated SIRT1 was important in the activation of genes coding for slower myosin heavy chain isoforms. Furthermore, while SIRT activation via resveratrol did modulate increases in IGF-I gene expression, it did not appear to modulate energy sensing AMP activated protein kinase (AMPK) vs. growth related Protein 70 S6 Kinase (p70S6K) signalling pathways. However, SIRT1 inhibition increased AMPK activity in both low and normal glucose with corresponding mean reductions in p70S6K in normal glucose conditions. This indicates that perhaps normal SIRT1 activity was required for appropriate AMPK activation, which may therefore prevent the suppression of p70S6K and the corresponding reductions in myotube size observed in SIRT1 inhibitor conditions. Furthermore, during low glucose induced myotube atrophy resveratrol reduced gene expression of the negative regulator of muscle mass, myostatin and protein degradative ubiquitin ligase enzyme, MUSA1. Overall, SIRT1 activation via a single dose of resveratrol appears to have a role in acutely negating the effect of low glucose induced myotube atrophy and promoting myotube hypertrophy when glucose is readily available.