Aujourd’hui, l’un des principaux défis dans l’industrie pétrolière, et particulièrement dans le domaine de l’exploration, est l’exploitation des nouvelles ressources dans des zones structuralement complexes.Nous savons que la géométrie et le glissement le long des failles actives modifie la distribution locale des contraintes. La connaissance du champ de contrainte perturbé actuel est importante pour l’étude des tremblements de Terre, pour la planification de forages ainsi que pour la prédiction de la fracturation induite par l’hydro-fracturation et la prédiction de la réactivation des fractures. Les contraintes perturbées passées, quant à elles sont responsables du développement des fractures naturelles (préexistantes). La détection et la modélisation de celles-ci sont essentielles tant dans le domaine pétrolier (migration et piégeage des fluides) pour une exploitation efficace et à moindre coût des réserves naturelles.Comprendre et quantifier le développement spatial et temporel de ces contraintes a un impact économique non négligeable. L'analyse des paléo-contraintes a été introduite dans un premier temps par Anderson (1905 & 1942) de manière intuitive, puis dans le milieu du siècle dernier, Wallace (1951) et Bott ( 1959) proposèrent les simples postulats que le champ de contrainte est homogène et que la direction du rejet est parallèle à la traction projetée sur le plan de faille. Beaucoup de méthodes d’inversion de contraintes reposent aujourd’hui sur ce principe.Afin d’étudier la validité de l’hypothèse Wallace et Bott, une comparaison avec les vecteurs de glissement générés à partir de modèles numériques (BEM) est effectuée. En testant l’influence de multiples paramètres (géométrie, contraintes au limites du modèle, friction, coefficient de poisson, demi-espace, pression de fluide dans la faille), il est montré que les failles à géométries complexes soumises à certaines contraintes aux limites peuvent engendrer des vecteurs glissements présentant des écarts important avec les la plus grande contraintes cisaillantes résolue sur le plan de faille. A l’inverse, la présence d’une forte friction de glissement permet, dans certaines conditions, de valider l’hypothèse de Wallace et Bott. On s’attache ensuite à comparer les résultats des inversions de contraintes basées sur l’hypothèse de Wallace et Bott (appelé méthode d’inversion classique de contraintes) avec une méthode géomécanique. Pour cela, une faille à géométrie complexe est utilisée dans une étude de sensibilité (contraintes aux limites, friction, échantillonnage) permettant d’analyser l’incertitude des résultats des deux méthodes d’inversion. Cette analyse est ensuite confrontée à l’étude d’un cas de terrain, montrant les avantages et inconvénients des méthodes d’inversions classiques de contraintes.Un des principaux défis de l’industrie pétrolière est l’exploitation des ressources des zones structuralement complexes telles que les réservoirs naturellement fracturés. Connaitre l’état de contraintes hétérogène passé permet d’optimiser la modélisation de ces fractures naturelles. Etant donné que les glissements sur les failles sont difficiles à observer dans les réservoirs pétroliers, les données de d’orientation de fractures (joints, failles, stylolites) sont naturellement prises en compte lors de l’inversion des contraintes. On montre, en utilisant divers exemples de terrain et d’industrie, que dans de tels cas, l’utilisation d’inversions basée sur la mécanique est beaucoup plus appropriée. Cependant, il est parfois difficile de déterminer le type cinématique de fracture observée le long des puits, et très souvent, les zones étudiées ont subi une tectonique polyphasée. La dernière partie vise donc à résoudre le problème des données de types cinématiques non identifiables (joints, failles, stylolites…) et étend parallèlement l’inversion mécanique des contraintes à la séparation de phases tectoniques. / Today, one of the main challenges in the oil industry, especially during the exploration phase, is the exploitation of new resources in structurally complex areas such as naturally fractured reservoirs, salt diapirs, mountain ranges, and unconventional reservoirs.We know that the geometry and sliding along active faults modifies the local stress distribution. Knowing the present day perturbed stress field is important for the study of earthquakes, for the planning of the borehole drilling and stability as well as for the prediction of fractures induced by hydro-fracturing and reactivation of natural fractures. In the other side, perturbed paleostress are responsible for the development of (pre-existing) natural fractures. The detection and modeling of the latter, are essential both in the oil industry (migration and trapping of fluids) for a cost efficient recovery of natural reserves.Understanding and quantifying the spatial and temporal development of the stress distribution has a significant economic and environmental impact. The analysis of paleo-constraints was intuitively introduced first by Anderson (1905 & 1942), then in the middle of the last century, Wallace (1951) and Bott (1959) proposed the simple hypothesis that (i) The stress field is homogeneous in space and constant in time, and that (ii) the slip direction is parallel to the traction projected on the fault plane which gives the direction of the shear stress. Many stress inversion methods are based on this hypothesis while recent studies raise doubts as to their compatibility with rock mechanics.In order to investigate the validity of the Wallace and Bott hypothesis, a comparison with vectors of slip generated with numerical models (BEM) is performed. By testing the influence of multiple parameters (geometry, boundary conditions, friction, Poisson’s coefficient , half-space, fault fluid pressure), it is shown that the complex geometry faults subject to specific boundary conditions can yield slip vectors with significant discrepancies with the maximum shear stress resolved on the fault plane. Conversely, the presence of a high sliding friction, allows under certain conditions, to validate the hypothesis of Wallace and Bott.We then focus on the task to compare the results of stress inversions based on the assumption of Wallace and Bott (called classical stress inversion methods) to a geomechanical method. For this, a complex fault geometry is used in a sensitivity analysis (boundary conditions, friction, sampling) to evaluate the uncertainty of the results of the two inversion methods. This analysis is then compared to a case study, Chimney Rock (Utah, USA), showing the advantages and disadvantages of the classical stress inversion methods.One of the main challenges of the oil industry is the exploitation of resource in structurally complex oil fields such as naturally fractured reservoirs. Knowing the heterogeneous paleostress allows to optimize the modeling of these natural fractures. Since slip on faults is hardly observed in petroleum reservoirs, fracture orientation data (joints, faults, stylolites) are naturally taken into account during the inversion of stresses. It is shown, using various field and industry examples, that in such cases the use of mechanical stress inversions is much more appropriate.However, it is sometimes difficult to determine the fracture kinematics observed along wellbores, and very often the studied regions underwent multiple tectonic phases. The final section aims to address the problem of data with unknown kinematic (joints, faults, stylolites ...) and expends the mechanical stress inversion to the separation of tectonic phases.

Made available in DSpace on 2014-12-17T15:43:48Z (GMT). No. of bitstreams: 1 KerlisonPO_DISSERT.pdf: 1641521 bytes, checksum: 5f1078757c465e02ee64ce8aff96f794 (MD5) Previous issue date: 2012-12-18 / The aim of this study was to comparatively evaluate the mechanical strength of squared and rectangular 2.0 mm system miniplates comparing them to the standard configuration with 2 straight miniplates in stabilizing fractures in the anterior mandible. Ninety synthetic polyurethane mandible replicas were used in mechanical test. The samples were divided into six groups of three different methods for fixation. Groups 1, 2 and 3 showed complete fractures in symphysis, characterized by a linear separation between the medial incisor, and groups 4, 5 and 6 showed complete fractures in parasymphysis with oblique design. Groups 1 and 4 were represented by the standard technique with two straight miniplates parallel to each other. Groups 2 and 5 were stabilized by squared miniplates and groups 3 and 6 were fixed by rectangular design. Each group was subjected to a mechanical test at a displacement speed of 10 mm/min on a universal testing machine, receiving linear vertical load on the region of the left first molar. The values of the maximum load and when displacements reached 5 mm were obtained and statistically analyzed by calculating the confidence interval of 95%. Fixation systems using squared (G2) and rectangular (G3) miniplates obtained similar results. No statistically significant differences with respect to the maximum load and the load at 5 mm displacement were found when compared to standard method in symphyseal fractures (G1). In parasymphysis the fixation method using squared miniplates (G5) obtained results without significant differences regarding the maximum load and the load at 5 mm when compared to the standard configuration (G4). The fixation method using rectangular miniplates (G6) showed inferior results which were statistically significant when compared to the standard configuration (G4) for parasymphysis fractures. The mechanical behavior of the fixation methods was similar, except when rectangular miniplates were used. The fixation methods showed better results with statistical significance in symphyseal fractures / O prop?sito deste estudo foi avaliar comparativamente a resist?ncia mec?nica de miniplacas quadradas e retangulares do sistema 2.0 mm, comparando-as ? configura??o padr?o, com 2 miniplacas retas, na estabiliza??o de fraturas na regi?o anterior de mand?bula. Noventa r?plicas de mand?bulas de poliuretano foram utilizadas no ensaio mec?nico. As amostras foram divididas em 6 grupos com 3 m?todos de fixa??o do sistema 2.0 mm. Os grupos 1, 2 e 3 apresentavam fraturas sinfis?rias completas, caracterizadas pela separa??o linear entre os incisivos mediais, e os grupos 4, 5 e 6 apresentavam fraturas parassinfis?rias completas com desenho obl?quo. Os grupos 1 e 4 foram representados pelo m?todo padr?o, com 2 miniplacas retas, dispostas paralelamente entre si. Os grupos 2 e 5 tiveram as mand?bulas estabilizadas por meio de miniplacas quadradas e os grupos 3 e 6, pelas retangulares. Cada grupo foi submetido a um teste mec?nico realizado por meio de uma m?quina de ensaio universal, na velocidade de 10mm/minuto, recebendo carga vertical linear na regi?o de primeiro molar esquerdo. Os valores da carga m?xima e da carga com deslocamento pr?-estabelecido em 5 mm foram obtidos e submetidos ? an?lise estat?stica a partir do c?lculo do intervalo de confian?a de 95%. Os sistemas de fixa??o utilizando miniplacas quadradas (G2) e retangulares (G3) obtiveram resultados similares, sem diferen?as estatisticamente significativas em rela??o ? carga m?xima e ? carga no deslocamento de 5 mm, quando comparada ? configura??o padr?o (G1), nas fraturas sinfis?rias da mand?bula. Nas fraturas parassinfis?rias, o m?todo de fixa??o utilizando miniplacas quadradas (G5) obteve resultados sem diferen?as estatisticamente significativas no que se refere ? carga m?xima e ? carga no deslocamento de 5 mm, quando comparadas ? configura??o padr?o (G4). O m?todo de fixa??o utilizando as miniplacas retangulares (G6) obteve resultados inferiores, estatisticamente significantes, quando comparado ? configura??o padr?o (G4) nas fraturas parassinfis?rias. O comportamento mec?nico dos m?todos de fixa??o estudados foi similar, exceto nas fraturas parassinfis?rias, quando se utilizaram as miniplacas com a configura??o retangular. Os m?todos de fixa??o utilizados apresentaram melhores resultados, com signific?ncia, nas fraturas sinfis?rias

O entendimento sobre os processos de fraturas em materiais à de grande importÃncia para a fÃsica e indÃstrias da construÃÃo civil. AtravÃs dos processos de fraturas podemos compreender melhor as propriedades elÃsticas dos materiais, como seu mÃdulo de Young macroscÃpico, tensÃo de ruptura e mÃdulo de rigidez. Podemos definir os processos de fraturas como sendo aqueles que dividem um sistema em duas ou mais partes, destruindo a conexÃo global dos elementos que o constituem. Nesse contexto, no primeiro capÃtulo à feito uma descriÃÃo matemÃtica das equaÃÃes da mecÃnica do contÃnuo, no segundo capÃtulo aborda-se o modelo de elementos discretos (DEM) que à um mÃtodo numÃrico capaz de descrever o comportamento mecÃnico de materiais granulados. No terceiro capÃtulo, construÃmos o modelo computacional para estudar, as propriedades mecÃnicas de 3 tipos de amostras, cristalina, amorfa e multifÃsica. O modelo computacional utilizado se mostrou bastante interessante e apresentou resultados que podemos considerar como sendo satisfatÃrios. / O entendimento sobre os processos de fraturas em materiais à de grande importÃncia para a fÃsica e indÃstrias da construÃÃo civil. AtravÃs dos processos de fraturas podemos compreender melhor as propriedades elÃsticas dos materiais, como seu mÃdulo de Young macroscÃpico, tensÃo de ruptura e mÃdulo de rigidez. Podemos definir os processos de fraturas como sendo aqueles que dividem um sistema em duas ou mais partes, destruindo a conexÃo global dos elementos que o constituem. Nesse contexto, no primeiro capÃtulo à feito uma descriÃÃo matemÃtica das equaÃÃes da mecÃnica do contÃnuo, no segundo capÃtulo aborda-se o modelo de elementos discretos (DEM) que à um mÃtodo numÃrico capaz de descrever o comportamento mecÃnico de materiais granulados. No terceiro capÃtulo, construÃmos o modelo computacional para estudar, as propriedades mecÃnicas de 3 tipos de amostras, cristalina, amorfa e multifÃsica. O modelo computacional utilizado se mostrou bastante interessante e apresentou resultados que podemos considerar como sendo satisfatÃrios. / The understanding about the fractures processes in materials has a big importance for physics and civil construction industries. Through the fractures processes, we can better understand the materialsâ elastics properties as its macroscopic Young module, rupture tension and rigidity module. We can define the fractures processes as those which divide a system into two or more parts, destroying the global connection of the elements that constitute it. In this context, in the first chapter, we can find a mathematical description of continuum mechanics equations. The second chapter discusses the model of Discrete Element(DEM), which is a numerical method capable of describing the mechanical behavior of granular materials. In the third chapter, we built the computational model for studying the mechanicals properties of three types of samples, crystalline, amorphous and multiphase. The computational model showed itself quite interesting and presented results which we can consider satisfactory. / The understanding about the fractures processes in materials has a big importance for physics and civil construction industries. Through the fractures processes, we can better understand the materialsâ elastics properties as its macroscopic Young module, rupture tension and rigidity module. We can define the fractures processes as those which divide a system into two or more parts, destroying the global connection of the elements that constitute it. In this context, in the first chapter, we can find a mathematical description of continuum mechanics equations. The second chapter discusses the model of Discrete Element(DEM), which is a numerical method capable of describing the mechanical behavior of granular materials. In the third chapter, we built the computational model for studying the mechanicals properties of three types of samples, crystalline, amorphous and multiphase. The computational model showed itself quite interesting and presented results which we can consider satisfactory.

Chan Cheung Shing. / Thesis (M.Phil.)--Chinese University of Hong Kong, 2007. / Includes bibliographical references (leaves 88-90). / Abstracts in English and Chinese. / Abstract --- p.ii / Acknowledgements --- p.iv / Table of Contents --- p.v / List of Figures --- p.viii / List of Tables --- p.xii / Abbreviations and Notations --- p.xiii / Chapter Chapter 1 --- Introduction --- p.1 / Chapter 1.1 --- Background and Objective --- p.1 / Chapter 1.2 --- Contribution --- p.4 / Chapter 1.3 --- Thesis Outline --- p.5 / Chapter Chapter 2 --- System Architecture --- p.6 / Chapter 2.1 --- Conceptual Design --- p.6 / Chapter 2.2 --- Sensing Device and Fall-Detection Algorithm --- p.7 / Chapter 2.3 --- Mechanical Part --- p.10 / Chapter Chapter 3 --- Mechanical Design --- p.11 / Chapter 3.1 --- Similar Products --- p.11 / Chapter 3.1.1 --- Airbag Restraining Systems in Automobiles --- p.11 / Chapter 3.1.2 --- Airbag Jackets for Motorcycle and House Riders --- p.12 / Chapter 3.2 --- Mechanism adopted --- p.12 / Chapter 3.2.1 --- Time Requirement of Inflator --- p.12 / Chapter 3.2.2 --- Mechanism and Design --- p.13 / Chapter 3.2.3 --- Actuator --- p.14 / Chapter 3.2.4 --- Punch --- p.15 / Chapter 3.2.5 --- Airbags --- p.18 / Chapter 3.2.6 --- Other Mechanisms Tried --- p.19 / Chapter 3.3 --- Prototype --- p.21 / Chapter 3.3.1 --- Implementation --- p.21 / Chapter 3.3.2 --- Demonstration --- p.23 / Chapter Chapter 4 --- Inflation Estimation --- p.25 / Chapter 4.1 --- Theory and Model --- p.25 / Chapter 4.2 --- Validation of Model --- p.28 / Chapter 4.2.1 --- Testing Equipment --- p.28 / Chapter 4.2.2 --- Preprocessing of Pressure Sensor Outputs --- p.28 / Chapter 4.2.3 --- Validation for Basic Equations --- p.29 / Chapter 4.2.4 --- Adjustment of Discharge Coefficients --- p.36 / Chapter 4.2.5 --- Validation for Discharging to a Fixed Volume --- p.40 / Chapter 4.2.6 --- Estimation of the Size of Airbag's Leakage Hole --- p.45 / Chapter 4.2.7 --- Validation for Discharging to an Airbag --- p.47 / Chapter 4.2.8 --- Time Delay due to Addition of a Pipe --- p.52 / Chapter 4.3 --- Summary of Experiments --- p.53 / Chapter 4.4 --- Limitation of Model --- p.54 / Chapter 4.5 --- Prediction of Inflation Time and Airbag Pressure --- p.55 / Chapter 4.5.1 --- Effects of Orifice Size and Vent Size on Airbag Pressure and Volume --- p.55 / Chapter Chapter 5 --- Force Attenuation Estimation --- p.58 / Chapter 5.1 --- Theory and Model --- p.58 / Chapter 5.1.1 --- Kelvin-Voigt Model --- p.59 / Chapter 5.1.2 --- Standard Linear Solid Support Model --- p.59 / Chapter 5.2 --- Simple Testing for Validation --- p.61 / Chapter 5.3 --- Summary of Experiment --- p.64 / Chapter 5.4 --- Estimation --- p.64 / Chapter 5.4.1 --- Force Attenuation Ability of Prototype --- p.64 / Chapter 5.4.2 --- Minimum Airbag Volume and Pressure Required to Reduce the Force --- p.65 / Chapter Chapter 6 --- Future Work --- p.66 / Chapter 6.1 --- Impact Test for Airbag System --- p.66 / Chapter 6.2 --- The Effective Mass of the Target User --- p.67 / Chapter 6.3 --- The Motion Data Collection --- p.68 / Chapter 6.4 --- Modification in the Inflator --- p.69 / Chapter Chapter 7 --- Conclusion --- p.70 / Appendix A Review of Basic Thermodynamics and Fluid Dynamics --- p.72 / Chapter A.1 --- Thermodynamics --- p.72 / Chapter A.2 --- Fluid Mechanics: Incompressible and Compressible Flow --- p.75 / Appendix B Derivation of Equations --- p.77 / Chapter B.1 --- Mass Flow Rate Equations --- p.77 / Chapter B.2 --- Relationship between Rate of Changes of Airbag Pressure and Volume --- p.80 / Chapter B.3 --- Pressure Change of Compressed Gas Cylinder --- p.82 / Chapter B.4 --- Dominating Factors in the Mass Flow Rate Equation --- p.83 / Appendix C Dimensions of Inflator --- p.85 / Appendix D Experimental Data --- p.86

L'intérêt porté aux milieux fracturés s'est développé dans le cadre de l'exploitation des nappes phréatiques et pétrolifères et la recherche de sites de stockage souterrains pour les déchets nucléaires de longue durée de vie. Les fractures peuvent en effet offrir des voies préférentielles d'écoulement beaucoup plus perméables que le milieu non fracturé environnant (matrice). Les fractures sont caractérisées par des distributions de longueurs et de perméabilités très larges. Lorsque elles sont interconnectées, elles forment des réseaux complexes de perméabilité variable dans lesquels les flux sont très chenalisés. <br />Le but de ce travail de thèse a été de rechercher les modèles de réseaux cohérents avec les observations locales (distributions de longueurs et d'ouvertures) et globales (à l'échelle du réseau). Ce travail s'inscrit dans le cadre d'une approche pluridisciplinaire destinée à utiliser des données obtenues à des échelles différentes (par exemple essais de puits et données de carottage). Des modèles de réseaux bidimensionnels prenant en compte les larges distributions de longueurs et d'ouvertures ont été étudiés numériquement et théoriquement. Les résultats montrent une grande diversité de structures d'écoulement allant de la fracture unique concentrant l'intégralité du flux au modèle homogène. Le type de structure d'écoulement dépend non seulement de la densité et des distributions de longueurs et de perméabilité de fractures mais aussi de l'échelle d'observation. Dans la plupart des modèles, une échelle de transition marque le passage de structures complexes extrêmement chenalisées à des milieux dans lesquels le flux se répartit dans différentes structures indépendantes. L'évolution des structures d'écoulement s'accompagne d'une dépendance d'échelle des propriétés hydrauliques telles que la perméabilité. La perméabilité croît jusqu'à la longueur de transition avant de se stabiliser aux échelles supérieures. Cette démarche de modélisation, fondée sur des observations effectuées à des échelles locales (caractéristique de la fracturation) et validée à des échelles globales (échelles du réservoir), fournit une large gamme de modèles d'écoulement admissibles et théoriquement spécifiables à partir de données de terrain. La modélisation a été étendue à la détermination de la connectivité de réseaux d'ellipses tridimensionnels.<br />Les modèles d'écoulement les plus pertinents mis au point en régime permanent ont été étudiés en régime transitoire. Les évolutions spatiales et temporelles du rabattement dépendent des propriétés topologiques et métriques du réseau de fractures. Une analyse en fonction de la distance des essais de puits effectués sur le site de Ploemeur (Morbihan) a permis d'obtenir des résultats similaires sur un site naturel. Cependant aucune correspondance totale n'a pu être dégagée, peut être à cause de la nature éventuellement tridimensionnelle du réseau naturel. Au-delà de la prédiction des tendances moyennes, les modèles étudiés sont destinés à fournir une évaluation de la précision de la prédiction en fonction de la quantité de données disponibles. Du point de vue décisionnel, il s'agit de pouvoir estimer le risque associé à la nature incomplète des données de terrain.

Various models featuring horizontal wells with multiple induced fractures have been proposed to characterize flow behavior over time in tight gas and shale gas systems. Currently, there is little consensus regarding the effects of non-ideal fracture geometries and coupled primary-secondary fracture interactions on reservoir performance in these unconventional gas reservoirs. This thesis provides a grid construction tool to generate high-resolution unstructured meshes using Voronoi grids, which provides the flexibility required to accurately represent complex geologic domains and fractures in three dimensions. Using these Voronoi grids, the interaction between propped hydraulic fractures and secondary "stress-release" fractures were evaluated. Additionally, various primary fracture configurations were examined, where the fractures may be non-planar or non-orthogonal. For this study, a numerical model was developed to assess the potential performance of tight gas and shale gas reservoirs. These simulations utilized up to a half-million grid-blocks and consider a period of up to 3,000 years in some cases. The aim is to provide very high-definition reference numerical solutions that will exhibit virtually all flow regimes we can expect in these unconventional gas reservoirs. The simulation results are analyzed to identify production signatures and flow regimes using diagnostic plots, and these interpretations are confirmed using pressure maps where useful. The coupled primary-secondary fracture systems with the largest fracture surface areas are shown to give the highest production in the traditional "linear flow" regime (which occurs for very high conductivity vertical fracture cases). The non-ideal hydraulic fracture geometries are shown to yield progressively lower production as the angularity of these fractures increases. Hence, to design optimum fracture completions, we should endeavor to keep the fractures as orthogonal to the horizontal well as possible. This work expands the current understanding of flow behavior in fractured tight-gas and shale-gas systems and may be used to optimize fracture and completion design, to validate analytical models and to facilitate more accurate reserves estimation.

One indication of increasing fragility of bone is the accumulation of microscopic cracks, or microdamage, within the bone matrix. Microdamage accumulates in bone of the elderly, when changes in bone material properties and matrix architecture coupled with a decrease in bone repair mechanisms compromise bone integrity. To preserve bone mass and reduce fracture risk, therapeutics such as alendronate are prescribed which increase bone volume fraction by decreasing the rate of bone turnover. However, concerns over adverse effects of prolonged turnover suppression have been reinforced by findings of increased microdamage density with alendronate use. Microdamage formation is not always pathologic, but extensive accumulation of damage can be an indicator of reduced bone quality. The work in this thesis explores the hypothesis that microdamage in bone of lower quality will form more easily and progress more extensively than in bone of higher quality. Microdamage initiation stresses and strains were obtained for trabecular bone from older females, older males, and younger females to determine whether thresholds for damage initiation were lower in older females. Results suggest that the stress threshold for damage initiation in older females may indeed be lower compared with younger females, and that normalized strain thresholds for severe damage formation in older males may be decreased compared with older females. Damage propagation was evaluated as a function of age and sex to determine whether damage in older women progressed more extensively than in younger women or men. Results suggest that bone from older individuals had decreased resistance to crack propagation evidenced by an increased number of severely damaged trabeculae which expanded in area under cyclic loading; however no sex differences were uncovered. Finally, the stress/strain thresholds for damage initiation were investigated in alendronate-treated bone, and results indicate that a decreased stress threshold was needed to initiate damage formation of a linear and severe morphology after one year of treatment. After three years of treatment, however, micromechanical properties recovered, perhaps due to increased matrix mineralization which increased tissue level stiffness.

We connect the Mimetic Finite Difference method (MFD) with the finite-volume two-point flux scheme (TPFA) for Voronoi meshes. The main effect is reducing the saddle-point system to a much smaller symmetric-positive definite matrix. In addition, the generalization allows MFD to seamlessly integrate with existing porous media modeling technology. The generalization also imparts the monotonicity property of the TPFA method on MFD. The connection is achieved by altering the consistency condition of the velocity bilinear operator. First-order convergence theory is presented as well as numerical results that support the claims. We demonstrate a methodology for using MFD in modeling fluid flow in fractures coupled with a reservoir. The method can be used for nonplanar fractures. We use the method to demonstrate the effects of fracture curvature on single-phase and multi-phase flows. Standard benchmarks are used to demonstrate the accuracy of the method. The approach is coupled with existing reservoir simulation technology. / text

No description available.

The purpose of this paper is the development of a model to investigate possible causal relationships among some of the commonly reported risk factors for the development of osteoporosis and consequential hip fracture. Comparison of hip fracture incidence between women of primarily European descent, referred to in the literature as Caucasians, and Japanese women is made. Studies report the incidence of hip fractures among Japanese women is lower than among Caucasian women. Numerous factors related to the development of osteoporosis are significantly different between Japan and the United States. The model helps explain the interrelationships among the variables involved in this observed geographical variation in hip fracture incidence. / Department of Anthropology