Cette thèse porte sur la navigation d'agents dans un environnement manufacturier. Le cadre général du travail relève de la navigation d'AGVs (véhicules autoguidés), transportant librement et intelligemment leur produit. L'objectif est de proposer des outils permettant la navigation autonome et coopérative d’une flotte d’AGVs dans des systèmes de production manufacturiers où les contraintes temporelles sont importantes. Après la présentation d'un état de l'art sur chaque domaine (systèmes manufacturiers et navigation d'agents), les impacts de la mutualisation entre ceux-ci sont présentés. Ensuite, deux problématiques, liées à la navigation d'agents mobiles dans des environnements manufacturiers, sont étudiées. La première problématique est centrée sur la planification de trajectoire décentralisée où une fonction d'ordonnancement est combinée au planificateur pour chaque agent. Cette fonction permet de choisir une ressource lors de la navigation afin d'achever l'opération du produit transporté le plus tôt possible. La première solution consiste en une architecture hétérarchique où les AGVs doivent planifier (ou mettre à jour) leur trajectoire, ordonnancer leur produit pour l'opération en cours et résoudre leurs propres conflits avec les agents à portée de communication. Pour la seconde approche, une architecture hybride à l'aide d'un superviseur, permettant d'assister les agents durant leur navigation, est proposée. L'algorithme de planification de trajectoire se fait en deux étapes. La première étape utilise des informations globales fournies par le superviseur pour anticiper les collisions. La seconde étape, plus locale, utilise les données par rapport aux AGVs à portée de communication afin d'assurer l'évitement de collisions. Afin de réduire les temps de calcul des trajectoires, une optimisation par essaims particulaires est introduite. La seconde problématique se focalise sur la commande coopérative permettant un rendez-vous d'agents non holonomes à une configuration spécifique. Ce rendez-vous doit être atteint en un temps donné par un cahier des charges, fourni par le haut-niveau de contrôle. Pour résoudre ce problème de rendez-vous, nous proposons une loi de commande à temps fixe (i.e. indépendant des conditions initiales) par commutation permettant de faire converger l’état des AGVs vers une resource. Des résultats numériques et expérimentaux sont fournis afin de montrer la faisabilité des solutions proposées. / This thesis is focused on agent navigation in a manufacturing environment. The proposed framework deals with the navigation of AGVs (Automated Guided Vehicles), which freely and smartly transport their product. The objective is to propose some tools allowing the autonomous and cooperative navigation of AGV fleets in manufacturing systems for which temporal constraints are important. After presenting the state of the art of each field (manufacturing systems and agent navigation), the impacts of the cross-fertilization between these two fields are presented. Then, two issues, related to the navigation of mobile agents in manufacturing systems, are studied. The first issue focuses on decentralized motion planning where a scheduling function is combined with the planner for each agent. This function allows choosing a resource during the navigation to complete the ongoing operation of the transported product at the soonest date. The first proposed approach consists in a heterarchical architecture where the AGVs have to plan (or update) their trajectory, schedule their product and solve their own conflict with communicating agents. For the second approach, hybrid architecture with a supervisor, which assists agents during the navigation, is proposed. The motion planning scheme is divided into two steps. The first step uses global information provided by the supervisor to anticipate the future collisions. The second step is local and uses information from communicating agents to ensure the collision avoidance. In order to reduce the computational times, a particle swarm optimization is introduced. The second issue is focused on the cooperative control, allowing a rendezvous of nonholomic agents at a specific configuration. This rendezvous must be achieved in a prescribed time, provided by the higher level of control. To solve this rendezvous, a fixed time (i.e. independent of initial conditions) switching control law is proposed, allowing the convergence of agent states towards a resource configuration. Some numerical and experimental results are provided to show the feasibility of the proposed methods.

<div>Glutamate is the principal excitatory neurotransmitter in the central nervous system. As one of the most abundant neurotransmitters, glutamate plays an essential role in many processes of the central nervous system and beyond. As a result, any disruption that causes an abnormal glutamate level can significantly impact the central nervous system's neurological functions. Glutamate excitotoxicity is a neuropathology that persists in many neurodegenerative disorders such as Parkinson's and Alzheimer's disease as well as in the traumatic brain and spinal cord injuries. Thus, the ability to obtain precise information about the extracellular glutamate level in the living brain and spinal cord tissue may provide new insights into the fundamental understanding of glutamate in neurological disorders and neurophysiological phenomena.</div><div><br></div><div>Conventional bioanalytical techniques that characterize glutamate levels <i>in vivo</i> have a low spatiotemporal resolution that has impeded our understanding of this dynamic event. The electrochemical sensor has emerged as a promising solution that can satisfy the requirement for highly reliable and continuous monitoring methods with an excellent spatiotemporal resolution for the characterization of extracellular glutamate concentration. In this thesis, I present various amperometric biosensors fabricated using a simple direct ink writing technique for<i> ex vivo </i>and <i>in vivo</i> glutamate monitoring.</div><div><br></div><div>The amperometric biosensor is fabricated by immobilizing glutamate oxidase on nanocomposite electrodes made of platinum nanoparticles, multiwalled carbon nanotubes, and a conductive polymer. The biosensors demonstrate good sensitivity and selectivity that can be inserted into a spinal cord and measure extracellular glutamate concentration. Additionally, another type of glutamate biosensor is fabricated from commercially available activated carbon with platinum microparticles. We utilize astrocyte cell culture to demonstrate our biosensor's ability to monitor the glutamate uptake process. We also present a direct measurement of glutamate release from optogenetic stimulation in mouse primary visual cortex brain slides. </div><div><br></div><div>Moreover, we explore a new type of material, perovskite nickelate-Nafion heterostructure, to fabricate biosensors and measure glutamate inside the mouse brain. Finally, by utilizing the nanocomposite ink and direct ink writing technique, we also fabricate the gold-ruthenium non-enzymatic glucose biosensor. We apply a modified Butler-Volmer non-linear model to evaluate the impact of geometrical and chemical design parameters of non-enzymatic biosensor performance. </div><div><br></div>

<div>The manufacturing industry has begun its transition into a digital age, where data-driven decisions aim to improve product quality, output, and efficiency. Decisions made based on manufacturing data can help identify key problem areas in an assembly line and mitigate any defects from progressing through to the next step in the assembly process. But what if the products’ as manufactured data was inaccurate or didn’t exist at all? Decisions based on incorrect data can lead to defective parts being passed as good parts, costing manufacturers millions of dollars in rework or recalls. When specifically referring to mechanically fastened assemblies, products that experience rotation, like an aircraft propeller, or compress to create a seal, like an oil pipe flange, all require specific torque pattern sequences to be followed during assembly. When incorrectly torqued, the parts can have catastrophic failures resulting in consumer injury or ecological contamination. This paper outlines the development and feasibility of a system and its components for tracking and error-proofing the assembly of bolted joints in an industrial environment.</div><div>Using a machine vision system, the system traces the tool location relative to the mechanical fastener and records which order the fasteners were torqued in, if an error is detected, the system does not allow the user to progress through the assembly process, notifying if an error is detected. The system leverages open source machine learning algorithms from TensorFlow2 and OpenCv, that allow efficient object detection model training. The proposed system was tested using a series of tests and evaluated using the STEP method. The data collected aims to understand the system's feasibility and effectiveness in an industrial setting. </div><div>The tests aim to understand the effectiveness of the system under standard and variable industrial work conditions. Using the STEP method and other statistical analysis, an evaluation matrix was completed, ranking the system's ability to successfully meet all predetermined benchmarks and successfully record the torque pattern used to assemble apart</div>

The research in this report seeks to develop a highly flexible geometry station for joining futureBody-in-White (BiW) assemblies. The goal is to eliminate the need for a complete reconstructionof a production line during integration of new car bodies in a contemporary production.Today's BiW production is performed in sequential lines, where joining equipment is arranged ina specific order for each model geometry. An increasing model portfolio forces manufacturers todevelop production systems that allow an integration of new models. Electrified alternatives ofexisting models are now developed and put into production. These models have similarappearance as conventional models, but with a completely different principle of driveline due tothe propulsion. This means that new interfaces and platforms have to be developed and mustnow be integrated into a current production. Today's production lines are not prepared forcoming changes, and current stations can only handle a limited number of variants. Integration ofnew geometries into a contemporary production line is not sufficiently efficient from aproduction perspective. The goal of the future is to make such an integration possible.Initially, current and future production scenarios were studied. Based on this, four types ofproduction scenarios, which a highly flexible geometry station can be integrated into, were set up.An integration can take place in different ways depending on how a highly flexible geometrystation is compounded, therefore, different cases were created and compared in a case study.Internal and external benchmarking of production systems were made to compare the availablesolutions for increasing stations flexibility in a BiW production.As reference for the project, a concept for a highly flexible geometry station has been developedand is therefore described initially before an additional depth has been realized. The furtherconceptualization of a highly flexible geometry in this report is presented in the form of amorphological composition of technologies that can increase a station's flexibility, as well asvisualization of a station principles through layouts and cycle time charts. The result of theanalysis generated several concepts that hold different degrees of capacity, footprint andflexibility. The focus was to achieve a high level of flexibility for integration of new models, withnew geometries, in a current production. The conclusion was that the highly flexible geometrystation can, in a contemporary production, produce independently in low volumes. Alternatively,produce higher volumes when it is integrated as a complement in a novel, not yet implemented,production concept. / Forskningen i denna rapport syftar till att utveckla en högflexibel geometristation för fogning avkommande Body-in-White-karosser (BiW). Målet är att eliminera behovet av en fullständigrekonstruktion av en produktionslinje under integrering av nya bilar i en samtida produktion.Dagens BiW-produktion sker i sekventiella liner, där fogningsutrustning är arrangerad i enspecifik ordning för respektive modellgeometri. Ett ökande antal modellalternativ drivertillverkare till att utveckla produktionskoncept som möjliggör integration av nya modeller.Elektrificerande alternativ till befintliga modeller utvecklas kontinuerligt. Dessa modeller ärutseendemässigt lika de konventionella modellerna, men med en helt annan princip för drivlina.Det innebär att nya gränssnitt och plattformar har tagits fram och måste nu integreras i ennuvarande produktion. Dagens produktionslinjer är inte förberedda för kommande förändringaroch nuvarande geometristationer kan endast hantera ett begränsat antal karosstyper. Integrationav nya karosstyper i en befintlig produktionslinje är inte är tillräckligt effektivt ur ettproduktionsperspektiv. Framtidens mål är att göra en sådan integration möjlig.Inledningsvis studerades nuvarande- och kommande produktionsscenarion. Utifrån det beskrevsfyra produktionstyper, vilket en högflexibel geometristation kan komma att integreras i. Enintegration kan ske på olika vis beroende på hur en högflexibel geometristation tillämpas, därförjämfördes olika fall av det i en Case-studie. En intern och extern benchmarking avproduktionssystem gjordes för att jämföra de lösningar som finns för att öka flexibiliteten i enBiW-produktion.Som referensunderlag till projektet har ett koncept för en högflexibel geometristation tagits framoch är beskrivet inledningsvis innan en ytterligare fördjupning har realiserats.Konceptualiseringen av en högflexibel geometristation i denna rapport är presenterad i form aven morfologisk sammansättning av teknologier som kan öka en stations flexibilitet, samtvisualisering av en principiell station genom layouter och cykeltidsdiagram. Resultatet av analysengenererade flera koncept som innehar olika grad av kapacitet, fabriksyta och flexibilitet. Fokus varatt uppnå en hög flexibilitetsnivå för integration av nya modeller, med nya geometrier, i ennuvarande produktion. Slutsatsen var att den högflexibla geometristationen kan, i en nutidaproduktion, producera självständigt i låga volymer. Alternativt producera högre volymer då denintegreras som ett komplement till ett ännu inte implementerat nytt produktionskoncept. / Die Forschung in diesem Bericht zielt darauf ab, eine hochflexible Geometrie-Station für das Fügen zukünftiger Rohbau-Baugruppen zu entwickeln. Das Ziel ist es, die Notwendigkeit einer vollständigen Rekonstruktion einer Produktionslinie während der Integration neuer Karosserien in einer modernen Produktion zu beseitigen. Die heutige Rohbau Produktion wird in sequenziellen Linien durchgeführt, wobei die einzelnen Fügeverfahren in einer bestimmten Reihenfolge, angepasst an die jeweilige Modellgeometrie, angeordnet sind. Ein zunehmendes Modellportfolio zwingt die Automobilhersteller zur Entwicklung von Produktionssystemen, die eine Integration neuer Modelle ermöglichen. Elektrifizierte Varianten bestehender Fahrzeugmodelle werden nun entwickelt und in Produktion gebracht. Diese Modelle haben ein ähnliches Erscheinungsbild wie herkömmliche Modelle, jedoch mit einem stark veränderten Antriebskonzept. Dies bedeutet, dass neue Schnittstellen und Plattformen entwickelt wurden und nun in eine aktuelle Produktion integriert werden müssen. Heutige Produktionslinien sind nicht auf kommende Änderungen vorbereitet und können nur eine begrenzte Anzahl von Varianten handhaben. Die Integration neuer Geometrien in eine moderne Produktionslinie ist aus Produktionssicht nicht effizient, aber soll in Zukunft das Ziel sein. Zunächst wurden aktuelle und zukünftige Produktionsszenarien untersucht. Darauf aufbauend wurden vier Arten von Produktionsszenarien erarbeitet, in die eine hochflexible Geometriestation integriert werden kann. Je nach Aufbau der Geostation kann eine Integration auf unterschiedliche Art und Weise erfolgen. Daher wurden in einer Fallstudie unterschiedliche Fälle erstellt und verglichen. Ein Benchmarking mit internen und externen Produktionssystemen wurde durchgeführt, um eine größtmöglichste Flexibilität der Stationen in einer Rohbau Produktion zu erzielen. Als Referenz für das Projekt wurde ein Konzept für eine hochflexible Geometriestation entwickelt und im Rahmen der Thesis dokumentiert, bevor eine zusätzliche Tiefe realisiert wurde. Die weitere Konzeptionierung einer hochflexiblen Geometrie-Station wird in Form einer morphologischen Zusammensetzung von Technologien präsentiert. Dieser kann die Flexibilität einer Station erhöhen und zudem die Visualisierung von Stationsprinzipien, beispielsweise durch Layouts oder Zykluszeitdiagramme, fördern. Das Ergebnis der Analyse erzeugte mehrere vi Konzepte, die unterschiedliche Grade an Kapazität, Grundfläche und Flexibilität beinhalteten. Der Fokus lag auf einer hohen Flexibilität bei der Integration neuer Modelle mit neuen Geometrien in einer aktuellen Produktion. Die Schlussfolgerung war, dass die hochflexible Geometriestation in einer zeitgemäßen Produktion in kleinen Stückzahlen produzieren kann. Alternativ ist die Geo-Station auch als Bestandteil eines noch umzusetzenden Produktionskonzepts integrierbar.

Este trabalho utiliza a Programação Linear Inteira Mista (MILP) para investigar as diferenças de produtividade encontradas em uma Linha de Montagem de Modelo Misto. A abordagem de solução foi através da construção e resolução de modelos matemáticos do problema de balanceamento de linhas de montagem de modelo misto (MALBP – Mixed-Model Assembly Line Balancing Problem), seguido do problema de sequenciamento de carros (PSC – Car Sequencing Problem). Uma simulação discreta foi utilizada para verificar os resultados dos modelos matemáticos. O estudo relata o caso real de uma linha de montagem da indústria automotiva das partes móveis das carrocerias de três diferentes veículos compartilhando a mesma linha de produção. A linha de produção é caracterizada como baixa cadência (de até 15 veículos/hora) e totalmente manual. A linha é constituída por mesas de rolos em série onde o acionamento é do tipo de passo não sincronizado. O objetivo é investigar como manter o melhor nível de produtividade da linha de produção e, ao mesmo tempo, manter a característica de flexibilidade para atender a uma demanda variável em volume e diversidade de produto. São apresentados resultados desse trabalho que indicam que é possível a obtenção de alguns balanceamentos flexíveis para alguns mixes de produtos, o que permite manter a diferença nos tempos de produção no limite de 6%, para esta correta combinação de balanceamento-sequenciamento. No entanto, verificando as demais combinações possíveis para os seis mixes de produtos avaliados, o tempo de produção apresentou diferenças de até 19%, dependendo da sequência de entrada dos produtos para um certo mix. Outro fator que também ocasionou diferenças dos tempos produtivos, de 20% em média, foi em relação a alocação/ausência de postos pulmões (buffers). O horizonte da análise, a priori, foi de um lote de produção de uma hora para o modelo matemático e de uma semana de produção para o modelo de simulação discreta. Os resultados obtidos no estudo indicam que é possível operar uma linha de montagem flexível com uma produtividade equiparável a linhas de montagem de único modelo, se cuidados relativos ao balanceamento e sequenciamento produtivos forem observados. Por outro lado, se as condições operacionais de balanceamento e sequenciamento para as linhas de montagem de modelos/produtos mistos não forem consideradas, as perdas acumuladas na taxa de produção podem ser significativas (por exemplo, tempos de produção para algumas condições de teste ultrapassaram em 30% o valor teórico estimado). / This work uses Mixed Integer Linear Programming (MILP) to investigate productivity differences found in a Mixed-Model Assembly Line. The solution approach was based on construction and resolution of mathematical models for the Mixed-Model Assembly Line Balancing Problem (MALBP), followed by the Car Sequencing Problem (CSP). A discrete simulation was used to check the results obtained by the mathematical models. The study reports the real case of an automotive metal line that assemblies the closures of three different vehicles, sharing the same production line. The production line is characterized as low cadence (e.g., up to 15 vehicles/hour) and fully manual. The line is formed by roller tables in series with unpaced devices. The main objective is to investigate how to maintain productivity, while maintaining the flexibility characteristic to meet a variable demand in volume and product diversity. Results of this study are presented and indicate that some flexible balancing mixes are viable. Production time differences of no more than 6% were observed in such flexible choices. However, the checking of some possible combinations for the six mixes of evaluated products showed a production time difference up to 19%, depending on the sequence of products for a certain mix. Another factor that also influenced production time differences, 20% on average, was the allocation of buffers. The horizon of analysis encompasses a lot of production of one hour, to the mathematical model, and a week for discrete simulation. The obtained results indicate that it is possible to operate a flexible assembly line with a level of productivity similar to a single product line, in case of careful choices in balancing/sequencing. On the other hand, if the operating conditions of balancing and sequencing were not taken into account the cumulative loss in throughput may be significant (e.g., for some studied cases, production time exceed 30% the theoretical value).

<p>The miniaturization and thinning of wearable, soft robotics and medical devices are soon to require higher performance modeling as the physical flexibility causes direct impacts on the electrical characteristics of the circuit – changing its behavior. As a representative flexible electronic component, the organic field effect transistor (OFET) has attracted much attention in its manufacturing as well as applications. However, as the strain and stress effects are integrated into multiphysics modelers with deeper interactions, the computational complexity and accuracy of OFET modeling is resurfacing as a limiting bottleneck.</p><p>The dissertation was organized into three interrelated studies. In the first study, the Mass-Spring-Damper (MSD) model for an inverted staggered thin film transistor (TFT) was proposed to investigate the TFT’s internal stress/strain fields, and the strain effects on the overall characteristics of the TFT. A comparison study with the finite element analysis (FEA) model shows that the MSD model can reduce memory usage and raises the computational convergence speed for rendering the same results as the FEA. The second study developed the generalized solid-state model by incorporating the density of trap states in the band structure of organic semiconductors (OSCs). The introduction of trap states allows the generalized solid-state model to describe the electrical characteristics of both inorganic TFTs and organic field-effect transistors (OFETs). It is revealed through experimental verification that the generalized solid-state model can accurately characterize the bending induced electrical properties of an OFET in the linear and saturation regimes. The third study aims to model the transient and steady-state dynamics of an arbitrary organic semiconductor device under mechanical strain. In this study, the fractional drift-diffusion (Fr-DD) model and its computational scheme with high accuracy and high convergence rate were proposed. Based on simulation and experimental validation, the transconductance and output characteristics of a bendable OFET were found to be well determined by the Fr-DD model not only in the linear and saturation regimes, but also in the subthreshold regime.</p>

<p>The purpose of this research experiment was to explore and implement a cost-effective automation solution into a low volume production line for loading parts onto a coordinate measuring machine (CMM) for dimensional inspection. Quality control practices have historically been separated from production process by inspection routines being performed in a controlled lab. The system demonstrated the possibilities of an in-process automation of the quality control process that was feasible to be implemented for small and mid-sized manufacturing companies. The process involved an APSX horizontal injection mold machine dispensing parts onto the conveyor belt. The conveyor belt was controlled by a Phoenix Contact PLC and two line sensors that provided two stopping point for cooldown before inspection. A MyCobot 320-M5 robotic arm was used to select the part off the line and places it into a fixture on a Hexagon coordinate measuring machine (CMM).</p>

<p>  </p> <p>Printed electronics (PE) is one of the fastest growing technologies in the 21^st century. Recent reports have shown that PE market will reach 4.9 billion by 2032. PE refers to additive deposition of materials to fabricate electrical circuits, interconnects, and devices. </p> <p>The quest for developing nondestructive processes that enables additive manufacturing of low-cost PEs on heat-sensitive substrates with novel functionalities has resulted in several recent developments in the field which includes investigation of selective and optical sintering processes such as photonic sintering and laser sintering, to name a few. Broadly, this dissertation is an effort to study these sintering technologies for additive manufacturing of bimodal (metal/metal, metal/inorganic, and metal/organic) printed material compositions.  </p> <p>In the first section, nondestructive sintering technologies is combined with chemical sintering to develop bimodal metallic conductive pastes for the fabrication of biodegradable and non-biodegradable printed devices for applications in food packaging and wireless smart drug delivery.</p> <p>Next, a process is developed via near-infrared (NIR) technology to enable soldering and mounting electrical components onto printed materials using low-temperature bimodal metal/organic solder pastes. The developed optimized process is used to fabricate a flexible printed hybrid device for remote assessment of the wound exudate absorption in dressings.</p> <p>Lastly, laser processing is used to fabricate an antibacterial bimodal silver containing glass ceramics coating directly on temperature-sensitive polymeric surgical meshes. The integrated bioceramic coating on the mesh exhibits long-lasting antibacterial properties against Gram-positive and Gram-negative strains of bacteria. </p> <p>The results of this dissertation will open a new route of research to fabricate low-cost devices with bimodal materials with applications in medical device, healthcare, and packaging industries. </p> <p><br></p>

<p>Micro- and nanoparticles (MNP) attract much attention owing to their unique properties, structural tunability, and wide range of practical applications. To deposit these important materials on surfaces for generating functional coatings, a variety of special delivery systems and coating/printing techniques have been explored. Herein, spray coating technique is a promising candidate to advance the field of nanotechnology due to its low-cost, high-deposition rate, manufacturing flexibility, and compatibility with roll-to-roll processing. Despite great advances, direct scalable spray writing of functional materials at high-spatial resolution through fine patterning without a need of vacuum and mask equipment still remains challenging. Addressing these limitations requires the development of efficient spray deposition techniques and novel manufacturing approaches to effectively fabricate functional coatings. To this end, this dissertation employs three different spray coating methods of (1) cold spray; (2) atomization-assisted supersonic spray, and (3) dual velocity regime spray to address the aforementioned limitations. A comprehensive set of coating materials, design principles, and operational settings for each spray system are tailored for rapid, direct, and sustainable deposition of MNP on various substrates. Besides, through the two-phase flow modeling, droplets dispersion and deposition characteristics were investigated under both subsonic and supersonic flow conditions to uncover the process-structure-property relationships of the established spray systems. Moreover, novel spray-based manufacturing approaches are developed to fabricate functional coatings in various applications, including (i) functional polymer metallization, (ii) printed flexible electronics, (iii) advanced thin-film nanocoating, (iv) laser direct writing, and (v) electronic textiles.</p>

Von Beginn der flexiblen Automatisierung mit numerisch gesteuerten Werkzeugmaschinen und der zugehörigen Programmier-Software bis zum gegenwärtigen Entwicklungsstand (Industrie 4.0) wird die historische Entwicklung von 1960 bis 2020 aus der Position eines aktiven Mitgestalters dargestellt. Interessanterweise vollzogen sich die wesentlichen Entwicklungsetappen für die ersten dreißig Jahre parallel in beiden deutschen Staaten. Aus den Lehren des Zweiten Weltkrieges wurden im Rahmen der UNESCO zum friedlichen Informationsaustausch geeignete wissenschaftliche Organisationen gegründet: • IFIP (Internationale Föderation für Informationsprozesse, speziell Arbeitsgrupp CAM • CIRP (Internationale Akademie der Fertigungstechniker) Mit der Berufung und aktiven Mitarbeit in diesen Organisationen war eine Plattform für die deutsch-deutsche und darüber hinaus internationale Kooperation gegeben. Ein besonderer Schwerpunkt für den geordneten Informationsaustausch im Rahmen der gesamten dynamischen Entwicklung im Gebiet der Produktionsautomatisierung war dabei die im 3-Jahres-Rhythmus durchgeführte Konferenzserie PROLAMAT (Programming Languages for Machine Tools), gestartet 1969 in Rom. Im weiteren Verlauf wurde dieser Begriff viel breiter für das gesamte Gebiet der automatisierten Informationsverarbeitung und Fertigung erweitert. Ein besonderer Höhepunkt war dabei die erfolgreichste PROLAMAT-Konferenz 1988 in Dresden. Parallel dazu erfolgten an der TU Dresden Entwicklungen in Richtung CAD/CAM-Labor und später CIM-TT (CIM-Technologietransferzentrum). Damit war an der TU Dresden 1989/90 ein Entwicklungsstand gegeben, der unmittelbar zu gemeinsamen deutsch-deutschen und internationalen EU-Projekten genutzt werden konnte. Dieses hohe Entwicklungsniveau wurde zur offiziellen Eröffnung des CIM-TT-Zentrums in den Eröffnungsreferaten durch den damaligen Wissenschaftsminister Dr. Riesenhuber und Ministerpräsident Prof. Biedenkopf gewürdigt. Durch die zum gleichen Zeitpunkt verfügte veränderte Nutzung des für das CIM-TT im Aufbau befindliche Gebäude durch die neugegründete Juristische Fakultät wurde der erfolgreich vorbereitete Weg verhindert. Unabhängig davon blieb meine fachliche Orientierung mit den gravierenden Weiterentwicklungen eng verbunden. Dazu trug das Sabbatical-Jahr in Norwegen und den USA 1992 maßgeblich bei. Mit dem Forschungsaufenthalt war die Entscheidungsvorbereitung für die vorgesehene Groß-Investition für das neueste generative Verfahren verbunden. Gleichzeitig mit dem fundierten Nachweis der bestgeeigneten sog. Rapid-Prototyping-Anlage vom deutschen Anbieter EOS München war die TU Dresden auf diesem neuen High-Tech-Gebiet 1992 in einer anerkannten Spitzenposition. Mit meiner Publikation eines der ersten Fachbücher im Gebiet Advanced Prototyping (jetzt Additiv Manufacturing) war darüber hinaus eine gute Basis für weitere innovative Aktivitäten gegeben Dazu gehört die Gründung einer High-Tech-Firma (SFM - Schnelle Fertigung von Modellen) mit bemerkenswerten beispielgebenden Ergebnissen. Hervorgehoben soll die zwanzigjährige aktive Kooperation mit der Universität Stellenbosch (RSA - Republik Südafrika), die unter anderem mit meiner Berufung zum Extraordinary Professor im Jahr 2003 verbunden ist. Mit der Eröffnung eines Technologie-Zentrums nach dem Vorbild des ursprünglichen CIM TT -Zentrums der TU Dresden konnte für Südafrika ein wertvoller Beitrag geleistet werden. Das gesamte Lebenswerk ist gekennzeichnet durch die Entwicklungsschritte von der Mathematisierung über die Algorithmierung bis hin zur Programmierung vielfältiger technologischer Sachverhalte. Die Ergebnisse sind in einer Anzahl von persönlichen Fachbüchern (z.T. übersetzt in das Russische und Ungarische) wie auch Konferenzberichten und mehr als 200 Veröffentlichungen (deutsch und englisch) dokumentiert.