Made available in DSpace on 2016-08-10T10:54:36Z (GMT). No. of bitstreams: 1 ZILENE DO SOCORRO SANTA BRIGIDA DA SILVA.pdf: 2232247 bytes, checksum: ee0c9b1410c53051a738452561c262cb (MD5) Previous issue date: 2015-03-13 / Objective: To analyze the epidemiological, clinical and behavioral characteristics of patients with AIDS accompanied by the Hospital for Tropical Diseases in Tocantins, from 2007 to 2013. Methods: A descriptive, retrospective and cross. Data were collected from 592 reporting forms and records of adult AIDS cases and child, the period under study, through adapted SINAN record, according to the inclusion and exclusion criteria. We used the chi-square test to see if there were significant differences (p <0.05) between the observed and expected frequencies and in all analyzes, adopting a significance level of 0.05. Results: excelled males (57.4%); aged 20-59 years (93.9%); the brown skin color (82.4%); Singles (65%); with occupancy type employees, self-employed or retired (75.8%); studied the elementary school (44.6%); resided in Tocantins (71.05%). Except gender (p = 0.0001), the other variables showed significant differences (p <0.0001); the cases were reported by the criteria Rio de Janeiro - Caracas: cachexia (16.8%) and asthenia (16.5%), CDC adapted: CD4 T lymphocyte count (51.3%), toxoplasmosis (11.7%) and pneumonia (11%) and 2.4% for criterion death; were alive until the end of data collection (72.5%); AIDS was reported in less than 1 year of HIV diagnosis (80.7%); the year 2013 had a higher incidence of AIDS notifications; exposure to HIV through sexual contact occurred (92.9%); were diagnosed by conventional tests (62.7%); in the notification: CD4 <350 cells - mm3 (79.9%) and viral load> 40 viral copies (77.2%); and last record: CD4> 500 cells - mm3 (49.5%) and viral load <40 copies to undetectable (57.1%); examination performed genotyping (2.4%); visceral leishmaniasis (35%) and pulmonary tuberculosis (21%) were the most prevalent and co-infections, toxoplasmosis (23%) and pneumocystosis (22%) were the major opportunistic infections; in relations: regular - irregular attendance to health services versus coinfection - IO, 56.7% of patients without regularity developed coinfection - IO (p <0.0001); regular - irregular attendance to health services versus death, 85.9% died without those regularly employed (p <0.0001); hospitalization versus coinfection - IO, 63.5% had coinfection - IO but not hospitalized (p <0.0001); coinfection - IO versus death, 71.7% of patients died with some coinfection (p <0.0001); 57.6% of patients used ART with AZT + 3TC + EFV at baseline and at the final on 42.3% used other combinations; the behavior of patients, 41.1% of men reported using or have used any legal or illegal drug (p = 0.0006); 85.7% of men reported not use or never used condoms during sexual intercourse (p = 0.4574); on the type of sexual partner, 93.3% of women and 69.1% of men reported having heterosexual relationship. Conclusion: The analysis of all variables and their results corroborate to achieve the objectives proposed in this study and to understand how it presents the profile of the AIDS epidemic at the local level, contributing to the management in control measures for the spread of AIDS in state and the region. / Objetivo: analisar as características epidemiológicas, clínicas e comportamentais dos pacientes com AIDS acompanhados pelo Hospital de Doenças Tropicais no Tocantins, no período de 2007 a 2013. Métodos: estudo descritivo, retrospectivo e transversal. Foram coletados dados de 592 fichas de notificação e prontuários de casos de AIDS adultos e criança, do período em estudo, através de ficha adaptada do SINAN, obedecendo aos critérios de inclusão e de exclusão. Foi aplicado o teste do Quiquadrado para verificar se havia diferenças significativas (p < 0,05) entre as frequências observadas e esperadas e em todas as análises, sendo adotado um nível de significância igual a 0,05. Resultados: sobressaiu o gênero masculino (57,4%); faixa etária entre 20 a 59 anos (93,9%); a cor parda da pele (82,4%); solteiros (65%); com ocupação tipo empregados, autônomos ou aposentados (75,8%); estudaram o ensino fundamental incompleto (44,6%); residiam no Tocantins (71,05%). Com exceção ao gênero (p = 0,0001), as demais variáveis apresentaram diferenças significativas (p < 0,0001); os casos foram notificados pelos critérios Rio de Janeiro-Caracas: caquexia (16,8%) e astenia (16,5%), CDC adaptado: contagem de linfócitos T CD4 (51,3%), neurotoxoplasmose (11,7%) e pneumonia (11%) e 2,4% por critério óbito; encontravam-se vivos até o final da coleta de dados (72,5%); foi notificado AIDS com menos de 1 ano do diagnóstico de HIV (80,7%); o ano de 2013 teve maior ocorrência de notificações de Aids; a exposição ao HIV ocorreu por via sexual (92,9%); foram diagnosticados por exames convencionais (62,7%); na notificação: CD4 < 350 cels-mm3 (79,9%) e carga viral > 40 cópias virais (77,2%); e último registro: CD4 > 500 cels-mm3 (49,5%) e carga viral < 40 cópias à indetectável (57,1%); realizaram exame de genotipagem (2,4%); a leishmaniose visceral (35%) e a tuberculose pulmonar (21%) foram as coinfecções mais prevalentes e, a toxoplasmose (23%) e a pneumocistose (22%) foram as principais infecções oportunistas; nas relações: comparecimento regular-irregular ao serviço de saúde versus coinfecção-IO, 56,7% dos pacientes sem regularidade desenvolveram coinfecção-IO (p < 0,0001); comparecimento regular-irregular ao serviço de saúde versus óbito, 85,9% faleceram aqueles sem regularidade ao serviço (p < 0,0001); hospitalização versus coinfecção-IO, 63,5% tiveram coinfecção-IO mas não hospitalizaram (p < 0,0001); coinfecção-IO versus óbito, 71,7% dos pacientes faleceram com alguma coinfecção (p < 0,0001); 57,6% dos pacientes utilizaram a TARV com EFZ + AZT + 3TC no início do tratamento e, na última consulta 42,3% utilizou outras combinações; quanto ao comportamento dos pacientes, 41,1% dos homens referiu usar ou já ter usado alguma droga lícita ou ilícita (p = 0,0006); 85,7% dos homens referiu não usar ou nunca ter usado preservativo nas relações sexuais (p = 0,4574); sobre o tipo de parceria sexual, 93,3% das mulheres e 69,1% dos homens informaram ter relacionamento heterossexual. Conclusão: A análise do conjunto de variáveis e seus resultados corroboraram para o alcance dos objetivos propostos neste estudo e para compreender como se apresenta o perfil da epidemia de Aids em âmbito local, contribuindo com a gestão nas medidas de controle para o avanço da Aids no estado e na região.

Background AIDS remains one of the world’s most serious health challenges affecting more females than men. The differences in the spread of Human Immunodeficiency Virus (HIV) among gender groups stem from biology, sexual behaviour and socially constructed gender differences between women and men in roles and responsibilities, access to resources and decision-making power. It could also be due to the females’ status in society which could be justified by lower economic and decision making ability. Purpose The purpose of this study was to explore and describe the role of gender in the spread of HIV among women of reproductive age in Ethiopia; with the view of developing gender sensitive HIV and AIDS prevention strategies. Methods The study used sequential mixed method with quantitative and qualitative paradigm. During first phase of the study, health facility based descriptive cross-sectional study design was used. Data was collected from 422 respondents using a structured questionnaire. Forty participants were recruited by purposive sampling from representatives working in reproductive health or related fields. Results About 83.2% of respondents reported that sexual intercourse discussion should be initiated by male partners. This showed that majority of respondents were dependent on their male partners in decision-making regarding sexual matters in their relationship. Multiple sexual partners were common among the respondents. One third of the respondents reported to have had intercourse with more than one partner during the past twelve months of the study period. Higher proportion of respondents (61.4%, n=259) had never used condom during sexual intercourse with their partner/s. As a result these risky sexual practices are a potential threat for spread of HIV and AIDS among women. Thus developed guidelines would alleviate the existing problems through implementation of strategies of HIV and AIDS prevention to enhance women’s status at household and different administrative structure level. Conclusion Gender disparities in relation to negotiating sexual relations among the study respondents were found to be still relevant. The culture that has placed men at the helm of leadership in sexual matters is strongly upheld and that includes who recommends use of preventive measures and who regulates when and how to enter into a sexual relationship. Guidelines for gender sensitive prevention strategies if applied appropriately would educate women and men to make decision about what directly affects their health / Health Studies / D. Litt. et Phil. (Health Studies)

Background AIDS remains one of the world’s most serious health challenges affecting more females than men. The differences in the spread of Human Immunodeficiency Virus (HIV) among gender groups stem from biology, sexual behaviour and socially constructed gender differences between women and men in roles and responsibilities, access to resources and decision-making power. It could also be due to the females’ status in society which could be justified by lower economic and decision making ability. Purpose The purpose of this study was to explore and describe the role of gender in the spread of HIV among women of reproductive age in Ethiopia; with the view of developing gender sensitive HIV and AIDS prevention strategies. Methods The study used sequential mixed method with quantitative and qualitative paradigm. During first phase of the study, health facility based descriptive cross-sectional study design was used. Data was collected from 422 respondents using a structured questionnaire. Forty participants were recruited by purposive sampling from representatives working in reproductive health or related fields. Results About 83.2% of respondents reported that sexual intercourse discussion should be initiated by male partners. This showed that majority of respondents were dependent on their male partners in decision-making regarding sexual matters in their relationship. Multiple sexual partners were common among the respondents. One third of the respondents reported to have had intercourse with more than one partner during the past twelve months of the study period. Higher proportion of respondents (61.4%, n=259) had never used condom during sexual intercourse with their partner/s. As a result these risky sexual practices are a potential threat for spread of HIV and AIDS among women. Thus developed guidelines would alleviate the existing problems through implementation of strategies of HIV and AIDS prevention to enhance women’s status at household and different administrative structure level. Conclusion Gender disparities in relation to negotiating sexual relations among the study respondents were found to be still relevant. The culture that has placed men at the helm of leadership in sexual matters is strongly upheld and that includes who recommends use of preventive measures and who regulates when and how to enter into a sexual relationship. Guidelines for gender sensitive prevention strategies if applied appropriately would educate women and men to make decision about what directly affects their health / Health Studies / D. Litt. et Phil. (Health Studies)