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  • About
  • The Global ETD Search service is a free service for researchers to find electronic theses and dissertations. This service is provided by the Networked Digital Library of Theses and Dissertations.
    Our metadata is collected from universities around the world. If you manage a university/consortium/country archive and want to be added, details can be found on the NDLTD website.
601

T cell function in patients with dilated cardiomyopathy /

Lindberg, Erika, January 2008 (has links)
Diss. (sammanfattning) Göteborg : Göteborgs universitet, 2008. / Härtill 3 uppsatser.
602

Effect of the cardiac glycoside, digoxin, on neuronal viability, serotonin production and brain development in the embryo

Van Tonder, Jacob John January 2007 (has links)
Thesis (MSc.(Anatomy)--Faculty of Health Sciences)-University of Pretoria, 2007. / Includes bibliographical references.
603

Leptin protects rat cardiomyocytes from H2O2-and hypoxia/reoxygenation-induced Apoptosis /

Shin, Eyun-Jung. January 2008 (has links)
Thesis (M.Sc.)--York University, 2008. Graduate Programme in Biology. / Typescript. Includes bibliographical references (leaves 77-94). Also available on the Internet. MODE OF ACCESS via web browser by entering the following URL: http://gateway.proquest.com/openurl?url_ver=Z39.88-2004&res_dat=xri:pqdiss&rft_val_fmt=info:ofi/fmt:kev:mtx:dissertation&rft_dat=xri:pqdiss:MR51626
604

Predicting survival probability for major congestive heart failure events in patients attaining a low peak respiratory exchange ratio during cardiopulmonary exercise testing

Kenjale, Aarti. January 1900 (has links)
Thesis (M.S.)--The University of North Carolina at Greensboro, 2008. / Directed by Paul Davis; submitted to the Dept. of Kinesiology. Title from PDF t.p. (viewed Jul. 20, 2010). Includes bibliographical references (p. 104-112).
605

Atrial fibrillation : on its trigger mechanisms, risks and consequenses /

Poçi, Dritan, January 2010 (has links)
Diss. (sammanfattning) Göteborg : Göteborgs universitet, 2010. / Härtill 5 uppsatser.
606

Congestive heart failure readmission rates following home visits /

Vallandingham-Stephens, Tracy. January 1900 (has links)
Thesis (M.A.)--Northern Kentucky University, 2006. / Made available through ProQuest. Publication number: AAT 1435896. ProQuest document ID: 1136092801. Includes bibliographical references (p. 28-29)
607

Έλεγχος τεχνητής καρδιάς

Παπαμιχάλης, Ευστράτιος 11 January 2010 (has links)
Το θέμα με το οποίο ασχολείται η παρούσα διπλωματική εργασία είναι ο έλεγχος τεχνητής καρδιάς. Πολλοί ερευνητές έχουν ασχοληθεί, από τη δεκαετία του 1950 ακόμα, με την μηχανική υποβοήθηση της κυκλοφορίας του αίματος. Τα τελευταία 10 χρόνια μάλιστα, η έρευνα έχει περάσει στο στάδιο της εφαρμογής σε ασθενείς που πάσχουν από σοβαρής μορφής καρδιοπάθεια. Η παρούσα εργασία ασχολείται, αρχικά, με την παρουσίαση της τεχνολογίας της μηχανικής υποβοήθησης της κυκλοφορίας που έχει αναπτυχθεί τα τελευταία 60 χρόνια. Έπειτα, παρουσιάζονται διάφορα μαθηματικά μοντέλα που έχουν προταθεί κατά καιρούς, τα οποία περιγράφουν το σύστημα της τεχνητής καρδιάς και παράλληλα παρουσιάζονται και τεχνικές ελέγχου οι οποίες καθιστούν το εκάστοτε μοντέλο λειτουργικό. Το μοντέλο που επιλέχθηκε, τελικά, στην παρούσα εργασία, περιγράφει την εξάρτηση του καρδιακού ρυθμού από την ένταση άσκησης σε κυλιόμενο διάδρομο τρεξίματος. Σκοπός της εργασίας είναι η προσαρμογή του μοντέλου στις απαιτήσεις της τεχνητής καρδιάς και ο έλεγχός του ώστε να παρουσιάζει την επιθυμητή απόκριση σε διάφορες εντάσεις άσκησης. / The subject of the present diploma thesis is control of an artificial heart. Many researchers have studied, even from the 1950’s, mechanical support of blood circulation. The last 10 years, research gave birth to applications that have been tested on patients suffering from congestive heart failure. As an introduction, we present the technology of mechanical support of blood circulation that has been developed over the last 60 years. We also present some mathematical models describing the artificial heart system with a reference to the control techniques that make each model functional. The model chosen for the present diploma thesis describes the heart rate response to exercise on a treadmill system. The target of this research is to adapt the chosen model to artificial heart specifications and to control the system so that it presents the desired response to a wide range of exercise intensities.
608

Patienters upplevelser av hur hjärtsvikt och dess symtom påverkar det dagliga livet : En litteraturbaserad studie / Patients' experiences of how heart failure and its symptoms affect daily life : A literature-based study

Karlsson, Mikaela, Kauder, Daniella January 2015 (has links)
Bakgrund: Hjärtsvikt är idag en av våra folksjukdomar och tros öka i framtiden. Det är ett kroniskt tillstånd som karaktäriseras av flera olika symtom så som dyspné och andfåddhet. Den vanligaste orsaken till hjärtsvikt är ischemisk hjärtsjukdom som utgör 50-75% av all hjärtsvikt. New York Heart Association Functional Classification är en funktionsklassificering som är baserat på patientens egna upplevelser av sjukdomen och är graderad från I-IV. Att lida av en kronisk sjukdom kan innebära flera olika former av lidande som till exempel sjukdoms-, livs- och vårdlidande. Syfte: Att beskriva patienters upplevelser av hur hjärtsvikt och dess symtom påverkar det dagliga livet. Metod: Litteraturbaserad studie som är grundad på elva vetenskapliga artiklar. Resultat: Hjärtsvikt påverkar hela människan både psykiskt och fysiskt i det dagliga livet. Livet blir begränsat på grund av de somatiska symtomen där även emotionella svårigheter blir tydliga. Att inte längre kunna utföra dagliga rutiner och delta i aktiviteter leder till en känsla av isolering och försämrad livskvalité. Slutsats: Hjärtsvikt har en tydlig påverkan i patientens dagliga liv där kroppen konstant är under förändring. Detta leder till en okänd upplevelse där framtiden för patienten är oförutsägbar. Hjärtsvikt är ett tillstånd där hela människan bör beaktas för att kunna lindra lidande. / Background: Heart failure is currently one of the major diseases and is believed to increase in the future. It is a chronic condition characterized by multiple symptoms such as dyspnea and shortness of breath. The most common cause of heart failure are ischemic heart disease, which constitutes 50-75% of all heart failure. New York Heart Association Functional Classification is a classification function which is based on the patient's own experience of the disease and are graded from I to IV. A chronic disease can cause suffering of disease, suffering of life and suffering of care. Aim: To describe patients' experiences of how heart failure and its symptoms affect daily life. Method: A literature-based study, in which the result is based on eleven scientific articles. Results: Heart failure affects the whole person, both mentally and physically in daily life. Life becomes limited because of the somatic symptoms and emotional difficulties is also known. The feeling of isolation becomes evident when the patient cannot participate in activities. Quality of life deteriorates when the daily routines can no longer be performed. Conclusion: Heart failure has a clear impact in the patient's daily life in which the body is constantly changing. This leads to an unknown experience where the future is unpredictable. Heart failure is a condition where the whole person should be considered in order to alleviate suffering.
609

Fatores associados a óbito e hospitalizações em uma clínica de insuficiência cardíaca / Factors associated with death and hospitalization in a heart failure clinic

Viviane Gomes Silva 12 March 2012 (has links)
Trata-se de um estudo descritivo, retrospectivo, com abordagem quantitativa cujo objetivo geral foi descrever e analisar o perfil epidemiológico dos pacientes com Insuficiência Cardíaca atendidos pela Clinica de IC de um Hospital Universitário. Os objetivos específicos orientam-se para:(a)Caracterizar os casos de Insuficiência Cardíaca segundo variáveis demográficas, variáveis clínicas, de diagnóstico e co morbidades;(b)Comparar as características clínicas e demográficas dos pacientes conforme grupos etiológicos identificados e fração de ejeção;(c)Determinar a taxa de mortalidade e hospitalização dos pacientes acompanhados pela clínica. Os dados analisados neste estudo são oriundos de um banco de dados onde são alocadas informações dos pacientes em atendimento ambulatorial da referida clinica.Para a análise dos dados foi utilizada a estatística descritiva, freqüências e porcentagens assim como tabelas e gráficos para a demonstração dos dados levantados.Os mesmos foram analisados através do software SPSS v.18.0, no qual se utilizou a estatística multivariada e curvas de sobrevida de Kaplan-Meyer.Os resultados apontam para uma predominância masculina de 60,1%, com idade de 63,5 anos. Na caracterização quanto à classe funcional observa-se que a predominante é a classe funcional I e II com 73,6% do total. Os pacientes assistidos apresentam uma média de 42% da fração de ejeção do ventrículo esquerdo e 61,7% possuem etiologia não isquêmica. Em nosso estudo, descrevemos 71,8% de portadores de disfunção sistólica. Os pacientes com etiologia isquêmica tinham predomínio do sexo masculino(70,7%), e a etiologia não isquêmica com uma prevalência maior do sexo feminino(45,5%vs 29,3%;p<0,001). Além disso, os pacientes isquêmicos eram mais idosos (p<0,001), com historia familiar de DAC(p<0,041), presença de diabetes (p<0,001). A disfunção sistólica(FE<50%) era predominante no grupo de pacientes isquêmicos(77%vs 69%; p=0,048).As classes funcionais mais avançadas(III e IV) foram menos predominantes nos indivíduos isquêmicos(32,5%) em relação aos não isquêmicos(41,3%;p=0,041).O paciente de etiologia isquêmica recebeu tratamento farmacológico semelhante ao não isquêmico com exceção do uso de AAS(p<0,001).Esses indivíduos cursaram com maior numero de internações por outras causas exceto IC(p<0,001) e maior numero de óbitos(p=0,007).Em relação à fração de ejeção, observou-se que indivíduos com FE>50% tinham predomínio do sexo feminino(p=0,006),mais idosos(p<0,001),de etiologia não isquêmica(p=0,048) e classes funcionais I e II(p=0,025).Indivíduos com FE<50% eram mais graves, apresentando maior número de internações por IC(37,8%vs20%;p<0,001), e internações por outras causas(27,2%vs17,5%;p=0,018) e maior número de óbitos (18%vs8,4%;p=0,005) do que os com fração de ejeção preservada. O resultado desse estudo teve como finalidade o conhecimento do perfil de uma população própria, com o objetivo de aprimorar a assistência prestada a ela. Os enfermeiros de Clínicas de IC, juntos com os profissionais da equipe multidisciplinar, desempenham papel fundamental no acompanhamento, orientação e educação desses pacientes. / It is a descriptive, retrospective, study with quantitative approach whose general objective was to describe and analyze the epidemiological profile of patients with heart failure treated in a heart failure clinic of a university hospital. The specific objectives are oriented to a) characterize the cases of heart failure according to demographic variables, clinical variables, diagnosis and comorbidities, (b) compare clinical and demographic characteristics of patients according to the main groups identified and etiologic fraction ejection, (c) Determine mortality and hospitalization rates of patients followed by the HF clinic. The data analyzed in this study come from a database which is allocated information of ambulatory patients referred to the clinic. For data analysis was used descriptive statistics with mean, median and standard deviation, frequencies and percentages ,tables and graphs to demonstrate the data collected as well multivariate statistical analysis and Kaplan-Meyers survival curves. They were analyzed using the software SPSS v.18.0. The results indicate a male predominance of 60.1% with an average age of 63.5 years. The functional class observed that was the predominant class I and II, 73.6% of the total. Patients have attended an average of 42% ejection fraction of left ventricle and 61.7% had non ischemic etiology. In our study, we describe 71.8% of patients with systolic dysfunction. Patients with ischemic etiology were predominantly male (70.7%), and non ischemic etiology with a higher prevalence of females (45.5% vs 29.3%, p<0.001). In addition, ischemic patients were older (p<0.001), family history of CAD (p<0.041), diabetes (p<0.001). Systolic dysfunction (EF<50%) was predominant in the group of ischemic patients (77% vs 69%, p=0.048).The more advanced functional class (III and IV) were less prevalent in ischemic subjects(32.5%) compared to non-ischemic (41.3%) (p=0.041). Patients with an ischemic etiology had highest number of hospitalizations for other causes than HF (p<0.001) and greater number of deaths (p=0.007). Regarding the ejection fraction was observed that individuals with EF > 50% were predominantly female (p=0.006), older (p<0.001), non-ischemic etiology (p=0.048) and functional classes I and II (p=0.025). Individuals with EF <50% were more severe, with higher number of hospitalizations for HF (37.8% vs 20%) (p<0.001), and hospitalizations due to other causes (27.2% vs 17.5%) (p=0.018) and higher number of deaths (18% vs 8.4%) (p=0.005) than those with preserved ejection fraction. The results of this study were aimed at the knowledge of the real profile of a population with distinct characteristics, in order to improve the care given to it. The nurses in HF clinics with other professionals in the multidisciplinary team, play a key role in monitoring, guidance and education of these patients.
610

Utilização de técnicas multivariadas na remodelação cardíaca em ratos com estenose aórtica induzida e submetidos a treinamento físico / Use of multivariate techniques on cardiac remodeling in rats with induced aortic stenosis and submitted to physical training

Ferreira, Francini Piccolo 23 March 2018 (has links)
Submitted by Francini Piccolo Ferreira null (francini.estatistica@gmail.com) on 2018-04-03T23:16:34Z No. of bitstreams: 1 Dissertação.pdf: 639951 bytes, checksum: 206253fce58059514913e1a69acab9bd (MD5) / Rejected by ROSANGELA APARECIDA LOBO null (rosangelalobo@btu.unesp.br), reason: Solicitamos que realize uma nova submissão seguindo as orientações abaixo: problema 1: Corrigir a informação colocada na Capra e folha de rosto De: Texto apresentado `a Universidade Estadual... Para: Dissertação apresentada à Universidade Estadual ... problema 2: Falta ficha catalográfica. A ficha deve ser inserida no arquivo PDF logo após a folha de rosto do seu trabalho. Assim que tiver efetuado essa correção submeta o arquivo, em PDF, novamente. Agradecemos a compreensão. on 2018-04-05T19:38:24Z (GMT) / Submitted by Francini Piccolo Ferreira null (francini.estatistica@gmail.com) on 2018-04-06T17:15:12Z No. of bitstreams: 1 Dissertação Francini versão final.pdf: 760805 bytes, checksum: 819324cafda873d3eebae84919c69deb (MD5) / Approved for entry into archive by ROSANGELA APARECIDA LOBO null (rosangelalobo@btu.unesp.br) on 2018-04-06T19:40:00Z (GMT) No. of bitstreams: 1 ferreira_fp_me_bot.pdf: 760805 bytes, checksum: 819324cafda873d3eebae84919c69deb (MD5) / Made available in DSpace on 2018-04-06T19:40:00Z (GMT). No. of bitstreams: 1 ferreira_fp_me_bot.pdf: 760805 bytes, checksum: 819324cafda873d3eebae84919c69deb (MD5) Previous issue date: 2018-03-23 / Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES) / Nas áreas de Ciências da Saúde e Biológicas, encontram-se vários estudos, considerando as mais variadas patologias. Contudo, os procedimentos de análise estatística utilizados nos dados não têm relevado a estrutura de variação envolvida no conjunto das variáveis biológicas, quando se procede o fracionamento para discutir cada variável isoladamente. No presente texto, será abordada a Remodelação Cardíaca em ratos com Estenose Aórtica induzida e submetidos a um determinado protocolo de Treinamento Físico, sob o aspecto de não fracionamento do conjunto de variáveis, a fim de considerar toda a estrutura de variação envolvida nas respostas biológicas. A Insuficiência Cardíaca (IC) é uma das principais causas de morte na atualidade. Em estudos experimentais, uma maneira de induzir a IC em um rato, para posteriormente estudar medidas que atenuem tal quadro clínico, é simulando uma Estenose Aórtica (EAo), por meio da implantação de um clipe milímetros acima de sua válvula aórtica. Estudos sugerem que treinamento físico suaviza os sintomas antecedentes à insuficiência cardíaca. A fim de comprovar tal hipótese, um grupo de pesquisadores da Cardiologia Experimental da Faculdade de Medicina de Botucatu - UNESP realizou alguns experimentos, em que ratos da variedade Wistar foram induzidos à Estenose Aórtica e, posteriormente, submetidos a um específico protocolo de treinamento físico. Para a avaliação da contribuição do treinamento na resposta cardíaca desses animais, outros ratos, aqui denominados Sham (sem implantação do clipe), também foram submetidos ao protocolo de treinamento. Portanto, quatro grupos foram formados: EAo (ratos induzidos à estenose aórtica); EAoTF (ratos induzidos à estenose aórtica e submetidos ao treinamento físico); Sham (sem treinamento físico); ShamTF (submetidos ao treinamento físico). Para o presente estudo, foram considerados apenas dois experimentos em que, no primeiro, foram mensuradas algumas variáveis a partir do ecocardiograma e do cardiomiócito isolado e, no segundo, do ecocardiograma e do músculo papilar. O objetivo foi utilizar técnicas multivariadas que considerem o estudo simultâneo das variáveis em cada experimento, visando concluir a respeito da inserção do treinamento físico como medida de atenuação do quadro clínico cardiológico. Os resultados das análises dos dados coletados, tanto do primeiro quanto do segundo experimento, mostraram que, de uma maneira geral, o treinamento físico ocasionou amenização das modificações cardiológicas presentes em animais induzidos à estenose aórtica, reaproximando em algumas características estes animais aos considerados saudáveis. / Heart failure (HF) is a leading cause of death nowadays. In experimental studies a way to induce the HF in a rats for subsequently studying measures that mitigate such clinical picture is simulating an aortic stenosis (EAo) through the implantation of a clip above the aortic valve. Studies suggest that physical training improves symptoms prior to heart failure. In order to prove this hypothesis, a group of researchers from the Experimental Cardiology of the Medical School of Unesp, Botucatu Campus, has made some experiments in which Wistar rats were induced to aortic stenosis and subsequently submitted to a specific protocol of physical training. For the assessment of the training contribution in cardiac response of these animals, other rats, here called Sham (without implantation of clip), also underwent the training protocol. Therefore, four groups were formed: EAo (rats induced to xv aortic stenosis); EAoTF (rats induced to aortic stenosis and submitted to physical training); Sham (without physical training); ShamTF (submitted to physical training). For this study were considered only two experiments in which at first were measured some variables from the echocardiogram and cardiomyocyte isolated and, in the second, the echocardiogram and papillary muscle. The goal of this research was to use multivariate techniques that consider the simultaneous study of the variables in each experiment aiming to conclude about the insertion of physical training as a mitigation of clinical cardiology. The results of the analyzes of both the first and the second experiments showed that, in general, physical training caused a slight alleviation of the cardiological changes present in animals induced to aortic stenosis, bringing closer in some characteristics these animals to those considered healthy

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