In the theoretical part of my thesis I define the illness, venous thromboembolic disease. The theoretical principles are used to determine the risks of the disease onset in women, primarily focused on the risk related to the hormonal contraception usage and the hormone replacement therapy. Attention is paid to the diagnosis, treatment and prevention of the DVT as well. In the following chapters the readers will be apprised with the treatment procedures, primarily from the nursing care perspective. The theoretical part of the thesis will be concluded with the casuistry of patient who suffers the thromboembolic disease and who was in my personal nursing care. The empirical part of my thesis is aimed on the qualitative and related quantitative research, which will be carry out by the help of the questionnaire. The questionnaire is based on the outcoume of the data analysis (casuistry) gained at the Clinic of Cardiology, FN Motol. The questionnaire is distributed and determined for wide group of women from non-medical environment (layman). The results of my research are giving the respons on the thesis's goals and hypotheses. The maion goal of my thesis is to define the women awareness of thromboembolic disease risks, in connection with the hormonal contraception usage and the hormone replacement...

Moral aspects of contraception from the perspective of present catholic couples Most women in productive age choose any form of conception control. Catholic Church accepts only natural contraceptive methods. Fertility awareness-based methods are cheap, ecological but for necessity of managing the method more complicated forms of contraception. It is also little promoted and by doctors mostly considered to be less reliable and that's why it is not often recommended by gynecologists in contrast to widely promoted and used hormonal contraception. The topic of this dissertation is how do present catholic couples cope with this problem. The aim of the work is to give comprehensive description of basic types of in present used contraception and after that bring the view of particular contraception methods from the perspective of the Catholic Church doctrine. By the questionnaire survey in practical part is evaluated what are the attitudes of present catholic coulpes to contraception in comparison with official Catholic Church doctrine. Keywords catholic couples, contraception, fertility awareness-based methods, symptothermal method, hormonal contraception

Objectif : Étudier l'association entre l’utilisation de contraceptifs hormonaux et le risque d'acquisition du VIH-1 chez les femmes au Malawi, en Afrique du Sud, en Zambie et au Zimbabwe. Devis : Analyses secondaires de 2887 femmes âgées de 17-55 ans ayant participé à l’étude HPTN 035, une étude de phase II/IIb sur l’efficacité de deux gels microbicides pour prévenir la transmission du VIH chez les femmes à risque. Méthodes : L'association entre l'utilisation de contraceptifs hormonaux et le risque d'acquisition du VIH-1 a été évaluée en utilisant des modèles de Cox. Des risques relatifs sont estimés où le groupe de référence est celui des femmes qui n’utilisent pas de contraceptifs hormonaux. De plus, un modèle multivarié de Cox est utilisé afin de contrôler pour les facteurs potentiellement confondants. Résultats : Les contraceptifs injectables ont été utilisés par 52,1% des femmes, alors que les contraceptifs oraux ont été utilisés par 20,7% de celles-ci. Pendant l'étude, il y a eu 192 séroconversions. L'incidence observée du VIH était de 2,28; 4,19 et 4,69 pour 100 personne-années pour les contraceptifs oraux, injectables et non hormonaux, respectivement. Lors de l’analyse multivariée, nous n'avons trouvé aucune association significative entre l’usage des contraceptifs hormonaux et l’acquisition du VIH-1. Le risque relatif ajusté (RRa) pour les contraceptifs oraux est de 0,573 (IC de 95% : [0,31-1,06]) et 0,981 (IC de 95% : [0,69 ; 1,39]) pour les contraceptifs injectables. Conclusions : Bien que cette étude ne démontre pas d’association entre l’usage des contraceptifs hormonaux et le VIH-1, nous concluons toutefois que ces méthodes de contraception ne protègent pas contre le VIH-1, et il est ainsi recommandé aux femmes utilisant des hormones contraceptives de toujours utiliser le condom pour prévenir l'infection au VIH-1. / Objective: To investigate the association between the use of hormonal contraceptive and the risk of acquiring HIV-1 infection in women from Malawi, South Africa, Zambia and Zimbabwe. Design: Secondary analyses of 2887 women aged 17-55 years who participated in the HPTN 035 trial, a Phase II/IIb trial on the efficacy of two microbicide gels to prevent HIV transmission in women at risk in Africa. Methods: The association between the use of hormonal contraceptive and the risk of acquiring HIV-1 was evaluated using Cox proportionnal models. Relative risks of exposed women were estimated using as a reference group the women who do not use hormonal contraceptives. In addition, a multivariate Cox model was used to control for potentially confounding factors. Results: Injectable contraceptives were used by 52.1 % of women, while oral contraceptives were used by 20.7% of them. During the study, there were 192 seroconversions. The observed HIV-1 incidence was 2.28, 4.19 and 4.69 per 100 woman-years for oral, injectable and non-hormonal contraceptive users, respectively. In multivariate analysis, we found no significant association between the use of hormonal contraceptives and HIV-1 acquisition. The adjusted relative risk (aRR) for oral contraceptives was 0.573 (95% CI: [0.31 to 1.06]) and 0.981 (95% CI: [0.69, 1.39]) for injectable contraceptives. Conclusions: Although this study did not demonstrate an association between hormonal contraceptive use and the risk of HIV-1 infection, we conclude, however, that these methods of contraception do not protect against HIV-1, and it is thus recommended that women using contraceptive hormones always use condoms to prevent HIV-1.