This thesis presents an engineering project measuring the effective wavelength of the CHARA Classic beam combiner on the CHARA Array. Knowing the actual effective wavelength of light observed is very important because that value is necessary for determining astrophysical parameters of stars. Currently, the value used for CHARA Classic data comes from a model of the system and is based on numbers published by the manufacturer of the filter; it is not derived from measurements done on the system directly. We use two data collection methods to observe standard stars of different spectral types and calculate the wavelength of light recorded by the instrument for each star. We find the best estimate of the effective wavelength for the CHARA Classic K′-band configuration to be 2.138±0.003μm, a 0.56% decrease from the previously adopted value of 2.150μm. Our result establishes the first estimate of the uncertainty in the effective wavelength.

An experimental technique has been presented to probe the mechanical behavior of thin film materials. The method is capable of tensile testing thin films on substrate and free-standing thin film specimens. A mechanical gripper was designed to address the current challenges in gripping thin film specimens. In order to measure the strain field across the gage section, the moire interferometry technique was used and the respective optical setup was designed. A versatile microfabrication process has been developed to fabricate free-standing dog-bone specimens. Aluminum was used as the model material; however, any other metallization material can be integrated in the process. Thin film specimens have been characterized using SEM, AFM, and TEM. A process has been developed to fabrication diffraction gratings on the specimen by FIB milling. Different grating geometries were fabricated and the diffraction efficiency of the gratings was characterized. The structural damage induced by the Ga+ ions during the FIB milling of the specimens was partially characterized using STEM and EDS. In order to extract the strain field information from the moire interferogram data, a numerical postprocessing technique was developed based on continuous wavelet transforms (CWT). The method was applied on simulated uniform and nonuniform strain fields and the wavelet parameters were tuned to achieve the best spatial localization and strain accuracy.

Optical Coherence Tomography (OCT) is a relatively new interferometric technology that allows for high-resolution and non-destructive tomographic imaging. One of its primary current uses is for in vivo and ex vivo examination of medical samples. It is used for non-destructive examination of ocular disease, dermatological examination, blood vessel imaging, and many other applications. Some primary advantages of OCT imaging include rapid imaging of biological tissue with minimal sample preparation, 3D high-resolution imaging with depth penetrations of several millimeters, and the capability to obtain results in real time, allowing for fast and minimally invasive identification of many diseases. Current commercial OCT systems rely heavily on optical fiber-based designs. They depend on the robustness of the fiber to maintain system performance in variable environmental conditions but sacrifice the performance and flexibility of free-space optical designs. We discuss the design and implementation of a free-space OCT interferometer that can automatically maintain its alignment, allowing for the use of a free-space optical design outside of tightly controlled laboratory environments. In addition, we describe how similar enhancements can be made to other optical interferometric systems. By extending these techniques, we can provide similar improvements to many related fields, such as interferometric metrology and Fourier Transform Spectroscopy. Improvements in these technologies can help bring powerful interferometric tools to a wider audience.

<p>Cancer is a disease that affects millions of people each year. While methods for the prevention and treatment of the disease continue to advance, the early detection of precancerous development remains a key factor in reducing mortality and morbidity among patients. The current gold standard for cancer detection is the systematic biopsy. While this method has been used for decades, it is not without limitations. Fortunately, optical detection of cancer techniques are particularly well suited to overcome these limitations. This dissertation chronicles the development of one such technique called Fourier domain low coherence interferometry (fLCI). </p><p>The presented work first describes a detailed analysis of temporal and spatial coherence. The study shows that temporal coherence information in time frequency distributions contains valuable structural information about experimental samples. Additionally, the study of spatial coherence demonstrates the necessity of spatial resolution in white light interferometry systems. The coherence analysis also leads to the development of a new data processing technique that generates depth resolved spectroscopic information with simultaneously high depth and spectral resolution. </p><p>The development of two new fLCI optical systems is also presented. These systems are used to complete a series of controlled experiments validating the theoretical basis and functionality of the fLCI system and processing methods. First, the imaging capabilities of the fLCI system are validated through scattering standard experiments and animal tissue imaging. Next, the new processing method is validated by a series of absorption phantom experiments. Additionally, the nuclear sizing capabilities of the fLCI technique are validated by a study measuring the nuclear morphology of in vitro cell monolayers.</p><p>The validation experiments set the stage for two animal studies: an initial, pilot study and a complete animal trial. The results of these animal studies show that fLCI can distinguish between normal and dyplastic epithelial tissue with high sensitivity and specificity. The results of the work presented in this dissertation show that fLCI has great potential to develop into an effective method for early cancer detection.</p> / Dissertation

Land subsidence and coastal erosion are worldwide problems, particularly in densely populated deltas. The Nile Delta is no exception. Currently, it is undergoing land subsidence and is simultaneously experiencing retreat of its coastline. The impacts of these long-term interrelated geomorphic problems are heightened by the economic, social and historical importance of the delta to Egypt. Unfortunately, the current measures of the rates of subsidence and coastal erosion in the delta are rough estimates at best. Sustainable development of the delta requires accurate and detailed spatial and temporal measures of subsidence and coastal retreat rates. Radar interferometry is a unique remote sensing approach that can be used to map topography with 1 m vertical accuracy and measure surface deformation with 1 mm level accuracy. Radar interferometry has been employed in this dissertation to measure urban subsidence and coastal change in the Nile Delta. Synthetic Aperture Radar (SAR) data of 5.66 cm wavelength acquired by the European Radar Satellites (ERS-1 and ERS- 2) spanning eight years (1993-2000) have been used in this investigation. The ERS data have been selected because the spatial and temporal coverage, as well as the short wavelength, are appropriate to measure the slow rate of subsidence in the delta. The ERS tandem coherence images are also appropriate for coastal change detection. The magnitude and pattern of subsidence are detected and measured using Permanent Scatterer interferometry. The measured rates of subsidence in greater Cairo, Mansura, and Mahala are 7, 9, and 5 mm yr-1, respectively. Areas of erosion and accretion in the eastern side of the delta are detected using the ERS tandem coherence and the ERS amplitude images. The average measured rates of erosion and accretion are -9.57 and +5.44 m yr-1, respectively. These measured rates pose an urgent need of regular monitoring of subsidence and coastline retreat in the delta. This study highlighted the feasibility of applying Permanent Scatterer interferometry in inappropriate environment for conventional SAR interferometry. The study addressed possibilities and limitations for successful use of SAR interferometry within the densely vegetated delta and introduced alternative strategies for further improvement of SAR interferometric measurements in the delta.

In this study a fiber optic interferometer (FOI) was designed and constructed to measure micron level clearances occurring in piston cylinder arrangements. A Cartesian model of the piston cylinder assembly is manufactured and lateral motion and vertical displacement are generated via a step motor, and micrometers, respectively. Clearance measurements are conducted in air and also in a lubricant. The range of vertical displacements is kept between 0-50 &amp / #956 / m, and the lateral motion is 13.5 mm. The effect of the step motor and lateral motion carriage on distance measurement is determined and this is used to correct displacement measurements.

Abstract ¡@¡@The motion when two parting in machine into contact can combine squeeze and sliding motion. This situation does occur for example in the meshing of gear teeth and in heavily loaded rolling elements bearing etc. In this study, the experiment is used to investigate the microscopic mechanism of the oil film under the combined squeeze and sliding motion. ¡@¡@The laser optical system is employed in the starting friction tester to measure the film thickness accurately by the principle of optical interferometry. High-speed video camera with the microscope records the dynamic characteristics of lubrication in the diminutive contact region. ¡@¡@Results show that the dimple becomes deeper with increasing squeeze velocity. When sliding velocity increases, the duration of dimple becomes shorter, but when the squeeze load increases, the dimple can keep longer. Furthermore, the dimple diameter increases with increasing the curvature radius of steel ball at the same experiment condition.

New millimeter wave interferometric, multifunctional sensors have been studied for industrial sensing applications: displacement measurement, liquid-level gauging and velocimetry. Two types of configuration were investigated to implement the sensor: homodyne and double-channel homodyne. Both sensors were integrated on planar structure using MMIC (Microwave Monolithic Integrated Circuit) and MIC (Microwave Integrated Circuit) technology for light, compact, and low-cost design. The displacement measurement results employing homodyne configuration show that sub-millimeter resolution in the order of 0.05 mm is feasible without correcting the non-linear phase response of the quadrature mixer. The double-channel homodyne configuration is proposed to suppress the nonlinearity of the quadrature mixer and to estimate the effect of frequency stability of a microwave signal source without the help of additional test equipment, at the loss of a slight increase of circuit complexity. The digital quadrature mixer is constituted by a quadrature-sampling signal processing technique and takes an important role in the elimination of conventional quadrature mixer's nonlinear phase response. Also, in the same displacement measurement, the radar sensor with the double-channel homodyne configuration provided a better resolution of 0.01mm, the best-reported resolution to date in terms of wavelength in the millimeter wave range, than the sensor employing simple homodyne configuration. Short-term stability of a microwave signal source, which is an important issue in phase sensitive measurement, is also considered through phase noise spectrum obtained by FFT spectral estimator at Intermediate Frequency (IF). The developed sensors demonstrate that displacement sensing with micron resolution and accuracy and high-resolution low-velocity measurement are feasible using millimeter-wave interferometer, which is attractive not only for displacement and velocity measurement, but also for other industrial sensing applications requiring very fine resolution and accuracy.

A novel optical calorimetry approach is proposed for the dosimetry of therapeutic radiation, based on the optical technique of Digital Holographic Interferometry (DHI). This detector determines the radiation absorbed dose to water by measurement of the refractive index variations arising from radiation induced temperature increases. The output consists of a time series of high resolution, two dimensional images of the spatial distribution of the projected dose map across the water sample. This absorbed dose to water is measured directly, independently of radiation type, dose rate and energy, and without perturbation of the beam. These are key features which make DHI a promising technique for radiation dosimetry. A prototype DHI detector was developed, with the aim of providing proof-of-principle of the approach. The detector consists of an optical laser interferometer based on a lensless Fourier transform digital holography (LFTDH) system, and the associated mathematical reconstruction of the absorbed dose. The conceptual basis was introduced, and a full framework was established for the measurement and analysis of the results. Methods were developed for mathematical correction of the distortions introduced by heat di usion within the system. Pilot studies of the dosimetry of a high dose rate Ir-192 brachytherapy source and a small eld proton beam were conducted in order to investigate the dosimetric potential of the technique. Results were validated against independent models of the expected radiation dose distributions. Initial measurements of absorbed dose demonstrated the ability of the DHI detector to resolve the minuscule temperature changes produced by radiation in water to within experimental uncertainty. Spatial resolution of approximately 0.03 mm/pixel was achieved, and the dose distribution around the brachytherapy source was accurately measured for short irradiation times, to within the experimental uncertainty. The experimental noise for the prototype detector was relatively large and combined with the occurrence of heat di usion, means that the method is predominantly suitable for high dose rate applications. The initial proof-of-principle results con rm that DHI dosimetry is a promising technique, with a range of potential bene ts. Further development of the technique is warranted, to improve on the limitations of the current prototype. A comprehensive analysis of the system was conducted to determine key requirements for future development of the DHI detector to be a useful contribution to the dosimetric toolbox of a range of current and emerging applications. The sources of measurement uncertainty are considered, and methods suggested to mitigate these. Improvement of the signal-to-noise ratio, and further development of the heat transport corrections for high dose gradient regions are key areas of focus highlighted for future development.

Two technologies, immersion and imprint lithography, represent important stepping stones for the development of the next generation of lithography tools. However, although the two approaches offer important advantages, both pose many significant technological challenges that must be overcome before they can be successfully implemented. For imprint lithography, special care must be taken when choosing an etch barrier because studies have indicated that some physical material properties may be size dependent. Additionally, regarding immersion lithography, proper image focus requires that the optical path length between the lens and substrate be maintained during the entire writing process. The work described in this document was undertaken to address the two challenges described above. A new mathematical model was developed and used in conjunction with AFM nano-indentation techniques to measure the elastic modulus of adhesive, thin polymer films as a function of the film thickness. It was found that the elastic modulus of the polymer tested did not change appreciably from the value determined using bulk measurement techniques in the thickness range probed. Additionally, a method for monitoring and controlling the optical path length within the gap of a nearly index-matching cavity based on coherent broadband interference was developed. In this method, the spectrum reflected for a cavity illuminated with a modelocked Ti:Sapphire laser was collected and analyzed using Fourier techniques. It was found that this method could determine the optical path length of the cavity, quickly and accurately enough to control a servo-based feedback system to correct deviations in the optical path length in real time when coupled with special computation techniques that minimized unnecessary operations. / text