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  • About
  • The Global ETD Search service is a free service for researchers to find electronic theses and dissertations. This service is provided by the Networked Digital Library of Theses and Dissertations.
    Our metadata is collected from universities around the world. If you manage a university/consortium/country archive and want to be added, details can be found on the NDLTD website.
121

Teleducação interativa: intercâmbio técnico-científico entre profissionais atuantes com fissura labiopalatina / Interactive teleducation: Technical-Scientific exchange between professionals who work with cleft palate

Ticiana Cristina de Freitas Zambonato 28 September 2012 (has links)
Devido a intensa relação entre a fissura labiopalatina e a deficiência auditiva, este trabalho teve como objetivo desenvolver e analisar a eficácia de um ambiente virtual de transmissão de informações sobre fissura labiopalatina e deficiência auditiva para profissionais, com a utilização da Teleducação Interativa. Como metodologia, foi desenvolvido um ambiente de aprendizagem no formato de um blog contendo informações sobre fissura labiopalatina e deficiência auditiva, englobando conteúdo específico direcionado a incidência, etiologia e tipos de fissura; deficiência auditiva; adaptação e seleção de AASI, funcionamento da tuba auditiva, otite média, etiologia da alteração de orelha média nos indivíduos com fissura labiopalatina, influência da otite no desenvolvimento da linguagem; tratamento para otite média: intervenção cirúrgica e acompanhamento sistemático e adaptação de AASI. Este blog foi disponibilizado na internet, sendo realizada a avaliação, por meio de dois questionários, o primeiro é o Emory (Emory University Rollins School of Public Health 1998), traduzido para o português (Bastos 2011), e o segundo questionário corresponde à avaliação específica do conteúdo do blog. A avaliação foi realizada por 75 profissionais do HRAC-USP, Bauru e outros, por demanda espontânea. O blog foi elaborado e disponibilizado na web pelo endereço: www.fissuraeaudicao.wordpress.com. No período analisado, de agosto de 2010 a 25 de junho de 2012, foram obtidas 13.746 visitas, sendo a página mais visitada sobre Fissura labiopalatina tipos de fissura, com 4.064 acessos. Além do Brasil diversos países acessaram o conteúdo do blog. O termo de busca mais utilizado foi tuba auditiva. A maioria dos avaliadores do blog (70,7%) era formada por profissionais Fonoaudiólogos. Destes, 89% consideraram o blog como excelente e 11% como adequado. Quanto ao conteúdo, dos 70 profissionais que responderam a este questionário como um todo, 69% consideraram excelente, 27% adequado e 4% consideraram o conteúdo pobre, sendo estes últimos fonoaudiólogos. Assim, um ambiente virtual, em formato de blog, contendo informações sobre fissura labiopalatina e deficiência auditiva para profissionais da área da saúde, foi desenvolvido e avaliado pela maioria dos juízes como excelente. / Due to the intense relationship between cleft palate and hearing loss, this work had as objective to develop and to analyze the effectiveness of a virtual environment of transmission of information on cleft palate and hearing loss for professionals, with the use of Interactive Teleducation. As methodology, an environment of learning in blog format was developed, containing information about cleft lip and palate and hearing loss, encompassing specific content directed to the incidence, etiology and types of cleft lip and palate; hearing loss; selection and adaptation of hearing aids, functioning of the auditory tube, otitis media, etiology of the alteration of the middle ear in individuals with cleft palate, influence of the otitis in the language development; treatment for otitis media: surgical intervention and systematic follow up and adaptation of hearing aids. This blog was made available on the Internet, and the evaluation was made through two questionnaires, being the first one Emory (Emory University Rollins School of Public Health 1998), translated into Portuguese (Bastos 2011), and the second questionnaire corresponds to the specific evaluation of the blog content. The evaluation was carried through by 75 professionals of the HRAC-USP-Bauru and others, through spontaneous demand. The blog was elaborated and made available on the web on the address: www.fissuraeaudicao.wordpress.com. In the analyzed period from August 2010 to June 25, 2012, there were 13.746 visits, being the most visited page about cleft lip and palate - types of cleft lip and palate, with 4.064 accesses. In addition to Brazil, several countries accessed the contents of the blog. The most used search term was auditory tube. The majority of the blog evaluators (70.7%) consisted of professional Speech and Language Pathologists. Of these, 89% considered the blog excellent and 11% adequate. In regard to the content, out of the 70 professionals who had answered this questionnaire as a whole, 69% had considered it excellent, 27% adequate and 4% considered the content poor, being these last ones Speech and Language Pathologists. Thus, a virtual environment, in blog format, containing information on cleft palate and hearing loss for health professionals was developed and evaluated by the majority of the judges as excellent.
122

Habilidade de atenção auditiva em crianças de sete anos com fissura labiopalatina: estudo comparativo / Auditory attention ability in 7 years old cleft palate and lip children: comparative study

Isabel Cristina Cavalcanti Lemos 02 March 2007 (has links)
A fissura labiopalatina é um indicador de risco para alterações de orelha média e estas podem prejudicar o desenvolvimento de habilidades auditivas como, por exemplo, a atenção, que é essencial para o aprendizado de novas habilidades, inclusive da comunicação oral e escrita. O estudo do processo atencional na população com fissura labiopalatina é algo recente e pouco explorado na literatura específica consultada, assim, este trabalho poderá contribuir com novos subsídios na área, uma vez que teve como objetivos: a) verificar o desempenho de crianças com essa anomalia craniofacial em dois testes, o THAAS e o teste dicótico de dígitos (etapa de escuta direcionada, que avaliaram processos de atenção auditiva); b) comparar o resultado com um grupo sem fissura labiopalatina e; c) verificar a associação entre os dois testes aplicados. Fizeram parte do estudo 55 crianças, de ambos os gêneros, na faixa etária de 7 anos a 7 anos e 11 meses, que foram distribuídas em dois grupos: a) grupo controle, formado por crianças sem fissura labiopalatina; b) grupo experimental, formado por crianças com fissura labiopalatina. Para ambos os grupos, o processo de avaliação constituiu-se em: aplicação de um questionário; bateria de testes auditivos convencionais; aplicação do teste da habilidade de atenção auditiva (THAAS) (FENIMAN, 2004) e do teste dicótico de dígitos etapa de escuta direcionada (SANTOS; PEREIRA, 1997). Foi possível observar que o desempenho do grupo com fissura labiopalatina foi inferior ao do grupo controle em todos os tipos de resposta do THAAS e diferença estatisticamente significativa ocorreu para o decréscimo da vigilâ (p=0,014). No teste dicótico de dígitos - etapa de escuta direcionada, o grupo com fissura labiopalatina apresentou porcentagens de acerto inferiores ao grupo controle, tanto para a orelha direita quanto para a orelha esquerda. A análise estatística mostrou interação estatisticamente significante entre grupo e gênero (p=0,026). Ao comparar o THAAS com o teste dicótico de dígitos, foi possível observar que existe associação entre os testes, mas, essa associação mostrou-se muito baixa (R²=0,27). As crianças com fissura labiopalatina apresentaram desempenho no THAAS inferior àquelas sem esta anomalia craniofacial, apenas para o decréscimo da vigilância. No teste dicótico de dígitos - etapa de escuta direcionada, somente as crianças do gênero feminino com fissura labiopalatina obtiveram índices de acerto inferiores às do grupo controle. Uma baixa associação foi verificada entre o THAAS e o teste dicótico de dígitos - etapa de escuta direcionada, permitindo supor que habilidades diferentes são responsáveis pelo desempenho nos dois testes. / Cleft lip and palate indicates risk to alterations in the middle ear. These risks may impair the development of some hearing abilities, such as attention, which is essential to learn new abilities, including oral and written communication. Studies on attention process with the population with cleft lip and palate are recent and not widely found in literature. Therefore, this study can contribute to the area. The aims of this study were to examine children with this craniofacial anomaly through two tests: The SAAAT and the Dichotic Digit test - directed hearing stage which evaluated the hearing attention processes; to compare the results with a group without cleft lip and palate; to verify the association between the two tests. 55 children, both genders, aged 7 to 7 years and 11 months old were divided in two groups to be submitted to the study. Experimental group consisted of children with cleft lip and palate and Control group consisted of children without it. Both groups were assessed through a questionnaire, conventional hearing tests battery, the Sustained Auditory Attention Ability test (SAAAT) (Feniman, 2004), and the Dichotic Digit test - directed hearing stage (Santos; Pereira, 1997). Experimental group showed lower performance than the control group in all kinds of answers of the SAAAT and, significant difference regarding decrease in vigilance (p=0,014). In the Dichotic Digit test the experimental group showed lower percentages of right answers than the control group, not only for the right ear but also for the left ear. Statistic analysis showed significant interaction between group and gender (p=0,026). When compared, the SAAAT and the Dichotic digit test had low association (R²=0,27). Experimental Group presented lower performance in the SAAAT only at the vigilance decrease. At the Dichotic Digit test female children with cleft lip and palate presented lower scores of right answers than the Control group. The SAAAT and The Dichotic Digit test - directed hearing stage - were not closely associated. Thus, it is possible to assume that different abilities are responsible for the performance in both tests.
123

Adaptação de aparelho de amplificação sonora individual em indivíduos com fissura labiopalatina / Hearing aid fitting in individuals with cleft palate

Ticiana Cristina de Freitas Zambonato 22 October 2007 (has links)
Objetivos: Caracterizar o perfil dos indivíduos com fissura labiopalatina e deficiência auditiva, adaptados com AASI, pela Divisão de Saúde Auditiva (DSA), HRAC/USP, Bauru e avaliar a efetividade e a satisfação da adaptação do AASI na amostra selecionada. Modelo: Análise dos prontuários, avaliação da efetividade do AASI pelo levantamento das características eletroacústicas, medidas com microfone sonda e teste de reconhecimento de sentenças no silêncio e no ruído e avaliação da satisfação pelo questionário QI-AASI. Local: Setor de AASI da DSA. Participantes: Para a caracterização do perfil, foram analisados os prontuários de 131 indivíduos e, destes, selecionados 8 com fissura labiopalatina, sem alterações associadas, deficiência auditiva condutiva e/ou mista e assíduos ao acompanhamento. Resultados: O perfil geral (n=131) caracterizou-se pela predominância de fissura transforame incisivo unilateral (27%), histórico de alterações de orelha média (56%) e intervenção cirúrgica (56%). Na amostra selecionada (n=8), a efetividade do AASI foi comprovada pelo melhor desempenho obtido com o aparelho, em comparação com as respostas sem ele, na avaliação proposta. A satisfação foi confirmada pelos escores elevados do questionário. Conclusões: O perfil geral dos indivíduos com fissura labiopalatina e deficiência auditiva, adaptados com AASI, caracterizou-se pela predominância do sexo masculino, fissura transforame incisivo unilateral, histórico positivo de alteração de orelha média, intervenção cirúrgica e deficiência auditiva sensorioneural bilateral de grau leve a profundo. Foi comprovada a efetividade e satisfação do AASI para os indivíduos com fissura labiopalatina e deficiência auditiva condutiva e/ou mista participantes deste estudo. É importante considerar a adaptação de AASI como alternativa para o tratamento desses indivíduos. / Aim: To characterize the profile and to assess efficacy and satisfaction of individuals with cleft palate and hearing loss that were hearing aids fitted at Divisão de Saúde Auditiva (DSA), Hospital de Reabilitação de Anomalias Craniofaciais, Universidade de São Paulo, Bauru. Model: Analysis of patients? files, assessment of the hearing aid efficacy by raising the electroacoustic characteristics, measurements with a probe tube and test of recognition of sentences in silence and noise and assessment of the satisfaction by questionnaire International Outcome Inventory for Hearing Aids. Local: Hearing aid division of the DSA. Participants: For the characterization of the profile, 131 files were analyzed from which 8 were selected with cleft palate, without associated alterations, conductive and/or mixed hearing loss, and assiduous to routine appointments. Results: The general profile (n=131) was characterized by the prevalence of the unilateral incisive transforamen cleft (27%), history of alterations of the middle ear (56%) and surgery intervention (56%). In the selected sample (n=8), the efficacy of the hearing aid was demonstrated by the better performance obtained with the hearing aid in comparison with those not using it in the proposed evaluation. The satisfaction was confirmed by the questionnaire elevated scores. Conclusions: The general profile of the individuals with cleft palate and hearing loss, adapted with hearing aid, was characterized by male predominance, unilateral incisive transforamen cleft, positive history of alteration of the middle ear, surgery intervention and moderate to profound bilateral sensorioneural hearing loss. It was possible to demonstrate the efficacy and satisfaction of the individuals with cleft palate and conductive and/or mixed hearing loss who participated in this work. It is important to consider the hearing aid fitting as an alternative to the treatment of such individuals.
124

Role of pneumococcal virulence genes in the etiology of respiratory tract infection and biofilm formation

Kurola, P. (Paula) 07 June 2011 (has links)
Abstract Streptococcus pneumoniae, pneumococcus, is a common cause of respiratory tract infections and also a common inhabitant of the upper respiratory tract of healthy people. At present, 93 different polysaccharide types have been identified and in addition to them, unencapsulated pneumococci are found especially in healthy carriers. Pneumococci are usually identified by using a bacterial culture combined with biochemical or immunochemical tests. Recently, new DNA-based methods, such as PCR, have been applied. Many PCR methods that detect pneumococci are targeted at genes which encode virulence factors such as pneumolysin, autolysin and pneumococcal surface antigen A. S. pneumoniae is a common causative agent of otitis media. In clinical trials, xylitol has been shown to decrease the occurrence of otitis media but the mechanism of action is not known. Xylitol has been shown to reduce pneumococcal growth and adherence to nasopharyngeal cells and its effect on the appearance of the pneumococcal polysaccharide structure has been shown by electron microscopy. Xylitol has also been demonstrated to inhibit biofilm formation of Staphylococcus aureus and Pseudomonas aeruginosa. Biofilms have been associated with otitis media and pneumococci have been shown to form biofilms. The purpose of this work was to study the role of capsular and other virulence genes in pneumococcal infection and biofilm formation. A new PCR method was developed to detect the pneumococcal capsule and it appeared to have potential when studying the pneumococcal etiology of pneumonia. Widely used PCR methods were used to study pneumococcal isolates, and conflicting results were obtained when the results were compared with conventional immunochemical methods. In addition, xylitol was shown to inhibit capsular gene expression and biofilm formation of pneumococci. Glucose and fructose appeared to enhance biofilm formation. The conflicting results between PCR and immunochemical methods suggest that further identification methods are needed in the diagnosis of pneumococcal infection. The observed inhibitory effect of xylitol on pneumococcal capsule gene expression and biofilm formation may partly explain the efficacy of xylitol in preventing acute otitis media in previous clinical trials. / Tiivistelmä Streptococcus pneumoniae, pneumokokki, on yleinen hengitystieinfektioiden aiheuttaja, joka esiintyy myös hengitysteiden normaalifloorassa. Pneumokokilla tunnetaan 93 kapselityyppiä ja näiden lisäksi etenkin oireettomilta nielukantajilta löytyy kapselittomia pneumokokkeja. Pneumokokin tunnistamiseen käytetään yleensä viljelyä sekä bio- ja immunokemiallisia testejä ja sittemmin tunnistuksen tukena on käytetty geeniteknologisia menetelmiä, kuten PCR. Useissa pneumokokin tunnistuksessa käytettävissä PCR-menetelmissä on käytetty kohdegeeninä virulenssitekijöitä, kuten pneumolysiiniä, autolysiinia ja pneumokokin pinta-antigeeni A:ta koodaavia geenejä. Pneumokokki on yleinen korvatulehdusten aiheuttaja. Kliinisissä tutkimuksissa ksylitolin on havaittu vähentävän korvatulehduksia, mutta vaikutusmekanismi on vielä epäselvä. Ksylitolin on osoitettu vähentävän pneumokokin kasvua ja kiinnittymistä nenänielun soluihin ja sen vaikutus polysakkaridikapselin ulkomuotoon on osoitettu elektronimikroskopialla. Ksylitolin on myös todettu vähentävän biofilminmuodostusta Staphylococcus aureus, ja Pseudomonas aeruginosa –bakteereilla. Biofilmin muodostuksen on ehdotettu liittyvän krooniseen korvatulehdukseen. Aiemmissa tutkimuksissa pneumokokin on osoitettu muodostavan biofilmejä. Työn tarkoituksena oli tutkia kapseli- ja muiden virulenssigeenien merkitystä pneumokokki-infektion diagnostiikassa ja biofilminmuodostuksessa. Työssä kehitettiin uusi PCR-menetelmä pneumokokin kapselin osoittamiseksi ja sillä todettiin olevan käyttömahdollisuuksia keuhkokuumeen pneumokokkietiologiaa tutkittaessa. Yleisesti käytettyjä PCR-menetelmiä tutkittiin pneumokokki-isolaateilla ja havaittiin vakavia ristiriitoja näiden ja perinteisten, immunokemiallisten tunnistusmenetelmien välillä. Lisäksi tutkimuksessa havaittiin ksylitolin vähentävän pneumokokin kapseligeenien ekspressiota ja biofilmin muodostusta. Sen sijaan glukoosi ja fruktoosi lisäsivät biofilmin muodostusta. Tutkimustulokset osoittivat ristiriidan perinteisten immunokemiallisten ja PCR-menetelmien välillä ja antavat aihetta uusien, tarkempien menetelmien käyttöönotolle pneumokokki-infektion diagnostiikassa. Tutkimuksen havainnot ksylitolin vaikutuksesta pneumokokin kapseligeeniekspressioon ja biofilmin muodostukseen voivat osittain selittää kliinisissä tutkimuksissa havaittua ksylitolin ehkäisevää vaikutusta korvatulehduksiin.
125

Noninvasive immunization strategies to target dendritic cells and protect against experimental otitis media due to nontypeable <i>Haemophilus influenzae</i>

Novotny, Laura Anne 21 March 2011 (has links)
No description available.
126

Predictive values of neurological examination, otoscopic examination and brainstem auditory evoked response (BAER) in calves with otisis media-interna

Finnen, Andrea 04 1900 (has links)
Présentement, le diagnostic d’otite moyenne-interne chez le veau est basé sur la présence de signes cliniques appropriés ainsi que les tests diagnostiques tels que la radiographie et la tomodensitométrie. L’objectif de cette étude prospective était d’évaluer les valeurs prédictives de l’examen neurologique, l’examen otoscopique et le test des potentiels auditifs évoqués (PAE) dans le diagnostic d’otite moyenne-interne chez le veau, en utilisant la tomodensitométrie comme test standard. Le deuxième objectif était de définir les valeurs de référence pour le PAE chez le veau normal et d’en décrire les anomalies chez des veaux atteints d’otite moyenne-interne. Dix-sept veaux de race Holstein entre 5-7 semaines d’âge ont été inclus. Tous les veaux ont eu un examen neurologique, un examen otoscopique et une évaluation des PAEs. Les veaux ont été tranquillisés avec de la xylazine intraveineuse (0,05-0,15mg/kg) pour la tomodensitométrie des bulles tympaniques afin d’évaluer pour la présence d’otite moyenne-interne. Selon les résultats de la tomodensitométrie, 11 des 17 veaux étaient atteints avec otite moyenne, 4 de façon unilatérale et 7 bilatéralement. Cinq ondes ont été identifiées de façon constante sur les tracés des PAEs des 6 veaux normaux. Les valeurs positives prédictives pour le PAE, l’examen neurologique et l’examen otoscopique étaient 94,7%, 91,7% et 66,7% respectivement. D’un point de vue clinique, le test le plus fiable dans le diagnostic d’otite moyenne-interne chez le veau est le PAE. Les anomalies ont été observées au PAE avant le développement des signes neurologiques chez certains veaux. / Currently, the antemortem diagnosis of otitis media-interna is based upon the presence of appropriate clinical signs and adjunctive diagnostic imaging including radiography and computed tomography. The purpose of this prospective study was to evaluate predictive values of neurological examination, otoscopic examination and BAER in calves for the diagnosis of otitis media-interna using computed tomography as the gold standard. The second objective was to define BAER reference values in normal calves and to describe BAER abnormalities in calves affected with otitis media-interna. Seventeen Holstein calves between 5 and 7 weeks of age were included. All calves had a neurological examination, otoscopic examination and BAER. Calves were sedated with intravenous xylazine (0.05-0.15 mg/kg [0.02-0.07 mg/lb]) for computed tomography of the tympanic bullae to evaluate for the presence of otitis media-interna. Based upon computed tomographic results, 11 of 17 calves were affected with otitis media, 4 unilaterally and 7 bilaterally. Five waveforms were consistently identified on BAER traces from 6 normal calves. The positive predictive value of BAER, neurological examination and otoscopic examination were 94.7%, 91.7% and 66.7% respectively. Clinically, the most reliable non-invasive diagnostic test to diagnose otitis media-interna in the calf is the BAER. Abnormalities were observed on BAER before the development of neurological deficits in approximately 40% of calves allowing earlier diagnosis.
127

Validation de l'échographie des bulles tympaniques pour le diagnostic d'otite moyenne chez le veau

Bernier Gosselin, Véronique 12 1900 (has links)
L'otite moyenne est une condition fréquente chez le veau et peut parfois être subclinique, rendant difficile son diagnostic à la ferme. L'objectif de cette étude est d’estimer la sensibilité et la spécificité de l'échographie des bulles tympaniques pour le diagnostic d'otite moyenne clinique et subclinique et de déterminer sa répétabilité. Quarante veaux âgés entre 19 et 50 jours ont été sélectionnés dans une ferme de veaux de grain, en fonction des résultats de l'échographie réalisée à la ferme (A). L'échographie a été réalisée une seconde fois par le même échographiste (A') et par un second échographiste (B), et le diagnostic noté pour chaque bulle tympanique comme étant négatif, suspect ou positif. Les images ont été enregistrées pour relecture et le diagnostic noté. Les veaux ont été euthanasiés, soumis en nécropsie et l'histologie a été utilisée comme méthode de référence. À l'histologie, 45 bulles tympaniques étaient atteintes d'otite moyenne et 35 bulles tympaniques étaient saines. Selon l'échographiste et la classification des bulles tympaniques suspectes, la sensibilité de l'échographie variait de 32% à 63% et la spécificité variait de 84% à 100%. La répétabilité était modérée, avec des valeurs de kappa de 0,53 entre A' et B, de 0,48 entre A et A', et de 0,58 et 0,75 pour la relecture de leurs images par A' et B respectivement. / Otitis media is a common disease in calves but can remain subclinical, making diagnosis challenging on the farm. The objective of this study is to estimate the sensitivity and specificity of the ultrasound imaging technique of tympanic bulla for the diagnosis of clinical and subclinical otitis media, and to determine its repeatability. Forty calves 19-50 days of age were selected from a veal calf farm, on the basis of results of ultrasound examination performed on the farm (A). Ultrasound examination was performed a second time by the same ultrasonographer (A') and by another ultrasonographer (B), and diagnosis was recorded for both tympanic bulla as negative, suspicious or positive. Images were recorded for further re-reading. Calves were euthanized and submitted for necropsy, and histopathologic diagnosis was used as gold standard. Based upon histology, 45 bullae were affected with otitis media and 35 bullae were unaffected. Depending on ultrasonographer and on classification of suspicious bullae, sensitivity varies from 32% to 63% and specificity varies from 84% to 100%. Repeatability is moderate, with kappa values of 0.53 for A'-B, 0.48 for A-A', and 0.58 and 0.75 for re-reading of A' and B, respectively.
128

The Chorda Tympani Nerve : Role in Taste Impairment in Middle Ear Disease and after Ear Surgery

Berling Holm, Katarina January 2017 (has links)
The chorda tympani nerve, also known as the taste nerve, runs uncovered through the middle ear cavity, a localization that exposes the nerve to pathological processes and surgical trauma in the middle ear. People operated on for otosclerosis tend to complain more about postoperative taste disturbances than those operated on for chronic otitis media. It has been suggested that this difference may be explained by gradual deterioration of chorda tympani nerve function caused by chronic otitis media infection and that further impairment caused by surgery is less noticeable in these patients. This thesis aimed to evaluate the function of the chorda tympani nerve, the effects of middle ear disease on taste and complications resulting from ear surgery for chronic otitis media or otosclerosis. This information will help to improve the ear surgeon’s ability to predict the prognosis of iatrogenic taste disturbances in patients with middle ear disease and after ear surgery. Taste was assessed using electrogustometry and the filter paper disc method before and after surgery for chronic otitis media or otosclerosis. Patients also completed questionnaires about symptoms and quality of life. The status of the chorda tympani nerve upon surgical opening of the ear and grading of the trauma to the nerve during the surgery were recorded. The ultrastructure of the chorda tympani nerve from healthy ears and from ears with chronic otitis media was examined. Electrogustometry and the filter paper disc method were evaluated. The results of electrogustometry and the filter paper disc method were highly reproducible, although their correlation was moderate. Patients with chronic otitis media, patients with a more traumatized nerve, female patients and younger patients were more likely to report postoperative taste disturbances. Most of the patients recovered their taste after 1 year. The quality of life study showed only minor changes after surgery. Electron microscopic observations of nerves from ears with chronic otitis media showed signs of structural degeneration, although signs of regeneration, such as sprouting were also observed. This results may explain the recovery of taste postoperatively and indicate that the nerve should be carefully handled during surgery.
129

Medidas de imitância acústica de banda larga em crianças com perda auditiva sensorial severa e profunda e diferentes achados timpanométricos / Wideband acoustic immittance measurements in children with severe and profound sensorineural hearing loss, and different tympanometric findings

Araujo, Eliene Silva 27 February 2015 (has links)
A avaliação da integridade do sistema tímpano-ossicular é um pré-requisito para que o processo de diagnóstico audiológico infantil possa ser concluído com precisão, assim, muito têm se discutido em relação aos procedimentos utilizados na prática clínica para definir a presença ou ausência de problema condutivo. Nesse sentido, as medidas de imitância acústica de banda larga mostram-se como uma opção para o avanço na área. Diante disso, surgiu o interesse em ampliar os conhecimentos e trazer as características das medidas de imitância acústica de banda larga nas diferentes condições de orelha média. O objetivo do estudo foi caracterizar as medidas de imitância acústica de banda larga com os estímulos tom puro e chirp em crianças com perda auditiva sensorial de grau severo e profundo e diferentes padrões timpanométricos. Foram avaliadas 187 orelhas de 98 crianças na faixa etária de seis a 60 meses de idade, subdivididas em grupos de acordo com a pressão e compliância obtidas na timpanometria com sonda de 226 Hz. As medidas de imitância acústica de banda larga foram realizadas por meio do sistema de medidas do Acoustics\' Middle-Ear Power Analyzer - MEPA, versão 5.0, utilizando os estímulos tom puro e chirp, com faixa de frequência de 211 a 6000 Hz. Os valores de compliância e pressão obtidos na timpanometria convencional foram correlacionados às medidas de imitância acústica de banda larga, adotando-se testes estatísticos apropriados, com nível de significância de 0,05. Os resultados obtidos evidenciaram o efeito das faixas de frequência (grave, média e aguda) em todas as medidas analisadas, com exceção do delay da reflectância. Foi constatada influência de pressões correspondentes a -100 daPa ou mais negativas e também para pressões positivas acima de 25 daPa, e compliâncias menores que 0,2 ml nas medidas de imitância acústica de banda larga. Além disso, houve diferença significante entre os estímulos tom puro e chirp para frequências baixas para a absorvância e magnitude da impedância, com maior reflexo da variação dos valores de compliância e pressão nos resultados obtidos com estímulo chirp. Conclui-se que as características das medidas de imitância acústica de banda larga estão relacionadas à condição de orelha média e a frequência do estímulo teste. Para o delay da reflectância observou-se uma ampla variabilidade entre frequências ao analisar os grupos subdivididos pela pressão e também na frequência de 258 Hz ao analisar os grupos subdivididos pela compliância. / The evaluation of the integrity of the tympanic-ossicular system is a prerequisite for the child audiology diagnostic process to be completed accurately, thus, much has been discussed in relation to the procedures used in clinical practice to define the presence or absence of conductive problems. Hence, the wideband acoustic immittance measurements show to be an option to the advance in the field. As a result, the interest in expanding the knowledge and bringing the characteristics of wideband acoustic immittance measurements in the different conditions of middle ear, emerged. This study aimed at characterizing the wideband acoustic immittance measurements using pure and chirp stimuli in children presented with severe and profound sensorineural hearing loss and different tympanometric standards. 187 ears of 98 children in the age range six-sixty months, subdivided into groups according to pressure and compliance achieved through tympanometry with a 226 Hz probe, were assessed. Wideband acoustic immittance measurements were performed by the measuring system of the Acoustics\' Middle-Ear Power Analyzer - MEPA, version 5.0, using pure and chirp tone stimuli, in a frequency ranging from 211 to 6000 Hz. The values of compliance and pressure obtained through conventional tympanometry were correlated with wideband acoustic immittance measures, by applying suitable statistical tests, with a 0.05 significance level. The results achieved evidenced the effect of frequency bands (low, medium and high) in all measures examined, with the exception of the reflectance delay. The Influence of pressures -100 daPa or more negative ones and also in positive pressures above 25 Pa, and compliance lower than 0.2 ml in the wideband acoustic immittance measurements, was verified. In addition, there was a significant difference between pure tone and chirp stimuli at low frequencies for impedance absorbance and magnitude, with a greater reflex of the variation of compliance and pressure values in the results obtained with the chirp stimulus. It is concluded that the characteristics of broadband acoustic immittance measures are related to the condition of middle ear condition and the frequency of the test stimulus. For Reflectance delay, a wide variability between frequencies was observed when analyzing the groups subdivided by pressure and also in the frequency of 258 Hz, when analyzing the groups subdivided by compliance.
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Habilidades auditivas verbais e temporais em crianças de 6 a 10 anos com e sem episódios comprovados de perda auditiva condutiva flutuante recorrente, nos primeiros anos de vida / Verbal and temporal auditory skills in children 6 to 10 years with and without episodes of proven floating recurrent conductive hearing loss, in the first years of life

Villa, Priscila Cruvinel 21 January 2014 (has links)
A otite média, afecção comum na infância, acarreta uma perda auditiva condutiva flutuante, pois uma vez tratada os limiares auditivos voltam aos valores normais. Preocupação ocorre quando estes episódios tornam-se recorrentes levando a criança a receber uma estimulação sonora inconsistente do sistema nervoso auditivo central, dificultando a percepção dos sons da fala. O objetivo do presente estudo foi investigar se crianças com episódios recorrentes e comprovados de otite média com efusão apresentam alterações das habilidades auditivas que compõe o processamento auditivo. Foram avaliadas 59 crianças com idade entre 6 e 10 anos, divididas em dois grupos: grupo experimental composto por 29 crianças de ambos os gêneros com histórico documentado de otite media com efusão, perda auditiva condutiva nos primeiros anos de vida e com e sem história de cirurgia para colocação de tubo de ventilação na idade pré-escolar e escolar; e grupo controle, composto por 30 crianças, pareadas em idade e gênero com o grupo experimental, mas sem história da afecção. Na avaliação das habilidades auditivas que compõe o processamento auditivo foram utilizados o teste fala com ruído (TFR), teste dicótico de dígitos (TDD) e teste Gaps-in-noise (GIN). Todas as crianças no momento da avaliação estavam livres de perda auditiva condutiva. Os resultados mostraram que: os dois grupos não apresentavam diferenças dos limiares tonais, no momento da avaliação; o grupo experimental apresentou resultados inferiores no TFR e GIN, tanto na análise quantitativa quanto na qualitativa; o TDD apenas na análise qualitativa diferenciou os dois grupos. Pode-se concluir, no presente estudo, , que crianças com história de otite média com efusão recorrente e persistente, nas fases pré-escolar e escolar, apresentaram transtorno do processamento auditivo. / Otitis media, a common affection in childhood, causes a fluctuating conductive hearing loss, because once treated the hearing thresholds back to normal values. Concern occurs when these episodes become recurring leading the child to receive an inconsistent sound stimulation auditory central nervous system, it difficult for the perception of speech sounds. The aim of this study was to investigate whether children with recurrent episodes of proven otitis media with effusion present alterations of auditory skills that composes the auditory processing. We evaluated 59 children with ages between 6 and 10 years, divided into two groups: the experimental group comprised of 29 children of both genders with documented history of otitis media with effusion, conductive hearing loss in the early years of life and with and without history of surgery for ventilation tube placement in preschool and school age; and the control group, consisting of 30 children, paired in age and gender with the experimental group, but no history of the disease. In the assessment of auditory skills that make up the auditory processing was used Speech in Noise Test (SNT), Dichotic Digits Test (DDT) and Gaps in Noise test (GIN). All children had at the time of assessment were free of conductive hearing loss. The results showed that: the two groups showed no differences in tonal thresholds, at the time of the assessment; the experimental group showed results below the SNT and GIN, both in qualitative and in quantitative analysis; DDT only in qualitative analysis differentiated the two groups. It can be concluded, with the results of the work, that children with a history of otitis media with effusion recurrent and persistent, pre-school and school phases, may have auditory processing disorder.

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