Thèse (M.A.) -- Université Laval, 1997. / Bibliogr.: f. ix-xiii. Publié aussi en version électronique.

Mestre -- Escola Nacional de Saude Publica, Rio de Janeiro, 1998.

Čechová, M. Barriers to Entry in the Pharmaceutical Industry. Diploma Thesis. Brno, 2013. This Diploma thesis aims to identify the Barriers to entry for those who have decided for entrepreneurial activity in the market for Drugs. The main aim of this work is to decide whether it is appropriate to Enter the market or not. In the Theoretical part of the work thoroughly describes the different business strategies, especially PEST analysis, analysis of the industry environment and analysis of competitive forces in the industry according to Porter. In the practical part of the thesis analyzes applied to the pharmaceutical industry and identifies the barriers to entry for new businesses that market. The thesis also includes the formation of the new pharmacy and all requirements related to it. In the final part of the thesis formulated recommendations which should serve prospective operators to decide whether to enter the industry or not.

The aim of the Diploma thesis is in strategic analysis of Agrochem joint-stock company Lanškroun. A high-quality strategy is an essential precondition for successful future of any company. It is the responsibility of any good management to create an adequate strategic analysis, which reflects on the past, takes the present into consideration and which respects the future as well. The basic starting point for a qualified company strategy proposal is a macroenvirons analysis consisting of the political, economic, social, technological and enviromental factors. The next step is a microenvirons analysis which concerns with the customers, suppliers, competition; and the Porter's Five Forces Competition Theory is applied. The last component analysis is the internal enviroment analysis comprising of factors of technical development, marketing factors, production and management production factors, factors of company and occupational resources and financial analysis. Based on the environs analysis, the SWOT analysis was established and a proper strategy for the above mentioned Agrochem joint-stock company Lanškroun suggested.

p. 1-71 / Submitted by Santiago Fabio (fabio.ssantiago@hotmail.com) on 2013-04-23T20:07:08Z No. of bitstreams: 1 11111ee.pdf: 1402726 bytes, checksum: 47dcda030901a96f687080b863e3c5a0 (MD5) / Approved for entry into archive by Maria Creuza Silva(mariakreuza@yahoo.com.br) on 2013-05-04T17:25:32Z (GMT) No. of bitstreams: 1 11111ee.pdf: 1402726 bytes, checksum: 47dcda030901a96f687080b863e3c5a0 (MD5) / Made available in DSpace on 2013-05-04T17:25:32Z (GMT). No. of bitstreams: 1 11111ee.pdf: 1402726 bytes, checksum: 47dcda030901a96f687080b863e3c5a0 (MD5) Previous issue date: 2010 / Apesar de a peste encontrar-se silente em todo o território brasileiro, seu agente etiológico, a bactéria Yersinia Pestis, permanece firmemente arraigada em seus focos naturais. Desta forma, e tendo em vista a existência de fatores condicionantes, não se pode desconsiderar que a doença, apesar de controlada, continua oferecendo riscos à população. A ocorrência de sorologia positiva para peste em carnívoros domésticos de algumas regiões pestígenas da Bahia nos últimos anos implica na necessidade de uma avaliação mais criteriosa, no intuito de verificar se ainda existe circulação do bacilo pestoso nessas áreas. Analisou-se, neste estudo, a presença de infecção por Y. pestis através do inquérito de soroprevalência em humanos, cães e roedores; e detecção da bactéria em roedores e pool de pulgas. A partir da aplicação de um questionário estruturado avaliou-se a associação existente entre fatores ambientais, sócio-econômicos e biológicos e a soroprevalência da infecção em humanos. Os 630 soros examinados (88 de humanos, 480 de cães, 62 de roedores) apresentaram-se não-reagentes para peste e as análises bacteriológicas realizadas em 14 roedores e 2 pool de pulgas não identificaram a bactéria. No entanto, tais resultados não configuram erradicação da doença no Estado. A natureza cíclica da peste indica que ela pode passar por longos períodos de silêncio e depois ressurgir acometendo um grande número de pessoas. Portanto, a manutenção de uma vigilância ativa e permanente se faz necessária para a detecção precoce da doença e desenvolvimento oportuno das medidas de controle pertinentes. / Salvador

Master thesis deals with the actual fluctuation in the birth rate in the Czech Republic focusing on the situation of kindergartens from the view-point of the government, founders, directors of kindergartens and the public (community). Three borough of the city Brno -- Bohunice, Medlánky a Žabovřesky were chosen for solving the situation. The proposed strategies are based on qualitative research, creating forecasts the number of required sites in kindergartens for the next 6 years and SWOT analysis. The strategies are designed to cope with fluctuations in the birth rate from the perspective of the founders of the kindergartens.

NĚMCOVÁ, S. Draft strategy for the future development of the company. Diploma thesis. Brno, 2014. This thesis describes the design strategy for the future development of Re-starant U Němců. The main objective is to analyze the activity of the company compared to its other competitors, considering the opportunities, threats, strengths and weaknesses and propose a strategy for the future development of the company in the ceremony, which is currently considering the best options remain on the market and increase sales. The work is focused on a more detailed examination of the potential in organizing weddings in the chosen company. The thesis is carried out a survey of potential customers, which is required to determine which factors influence the selection of place for wedding. According to the methodology used, it was found that the proposed strategy in holding festive events, especially in the organization of weddings has the potential to increase the company's competitiveness.

Made available in DSpace on 2016-03-07T19:21:00Z (GMT). No. of bitstreams: 0 Previous issue date: 2015-10-02. Added 1 bitstream(s) on 2016-03-07T19:24:55Z : No. of bitstreams: 1 000857857.pdf: 713336 bytes, checksum: ab84264d137dfc3385c359eec0183281 (MD5) / Os membros do gênero Pestivirus apresentam grande semelhança antigênica entre si. A reação sorológica cruzada entre o Vírus da Peste Suína Clássica (CSFV) e o Vírus da Diarreia Viral Bovina (BVDV) é de grande importância, e interfere em programas de erradicação da Peste Suína Clássica (PSC). Este trabalho teve como objetivos determinar a prevalência de anticorpos anti-BVDV em suínos de criações não tecnificadas, associar fatores de risco e buscar vínculos epidemiológicos entre rebanhos através do geoprocessaemento. Para tal, 360 amostras de soro de suínos provenientes de 56 propriedades rurais da região nordeste do Estado de São Paulo foram submetidas ao teste de virusneutralização (VN) utilizando os genótipos BVDV-1 estirpe Singer e BVDV-2 estirpe VS253. Foram detectados 4,72% (17) de amostras reagentes na VN, e 26,79% (15) rebanhos apresentaram pelo menos um animal reagente. Não foi possível associar fatores de risco. O estimador de intensidade de Kernel indicou áreas de alto risco de ocorrência da enfermidade e, juntamente com a análise de correspondência múltipla apontou associação com a presença de rebanhos de bovinos, quantidade mediana de leitões e rebanho suíno mediano nas propriedades da região. Ressalta-se a importância dos bovinos na ocorrência de infecções pelo BVDV em suínos, assim como a problemática no diagnóstico e levantamento epidemiológico para vigilância de PSC devido a presença de anticorpos anti-BVDV nos animais / The members of the Pestivirus gender have great antigenic similarity. The serological cross-reaction between the Classical Swine Fever Virus (CSFV) and the Bovine Viral Diarrhea Virus (BVDV) usually interferes with Classical Swine Fever (CSF) eradications programs. This study focused on establishing the prevalence of antibodies for the BVDV in pigs of non-technified rearing farms, associate risk factors and use geospatial analysis tools to correlate positive herds. A set of 360 serum samples from 56 herds located in the northeastern region of the state of São Paulo were analyzed by the virusneutralization test (VN), using the genotypes BVDV-1 strain Singer and BVDV-2 strain VS253. During the sample collection, a questionnaire was applied to the farmers in order to obtain epidemiological information of the herd. 4,72% (17) of the samples were positive in the VN and 26,79% (15) of the herds had at least one positive animal. It was not possible to associate risk factors; however, the variable use of milk serum in the feed showed a tendency to be associated with the occurence of the disease. The Kernel intensity estimator showed three high risk of occurence areas, which were associated with the presence of bovine herds, medium quantity of piglets in the herd and medium size of total swine herd. The results highlight the importance of bovines in the prevalence of swine BVDV infections and the difficulties in diagnostic tests and CSF surveillance actions due to the serological cross-reaction between BVDV and CSFV antibodies

O presente trabalho discute a construção sociotécnica da peste bubônica no Rio de Janeiro de 1897 a 1906. Tem como aporte teórico a teoria do ator-rede e como metodologia o acompanhamento de cientistas, médicos e políticos brasileiros interessados no combate à peste, analisando as polêmicas que se envolveram, e que redes sociotécnicas foram por eles mobilizadas. As fontes utilizadas foram: trabalhos científicos publicados no Brazil-Medico; debates veiculados na imprensa diária e os relatórios da Diretoria Geral de Saúde Pública (DGSP). As principais polêmicas foram em torno do tempo de incubação, letalidade e forma de transmissão da doença. A incubação implicava diretamente no tempo em que os navios ficariam submetidos à quarentena e o Governo Federal acreditava que ela durava 20 dias. Entretanto, pressões exercidas por diferentes atores, como a Associação Comercial de Santos, foram aos poucos mudando essa política e também a compreensão do período de incubação e da letalidade da doença. Em 1904, as quarentenas contra a peste foram extintas no Brasil e era consenso a doença não ser tão letal nem ficar incubada por um período superior a 10 dias. A questão da transmissão implicava diretamente na adoção de medidas sanitárias. Em 1900, o Governo Federal acreditava que a doença era transmitida pelo ar, ou por objetos, por isso a adoção de desinfecção de casas e no isolamento de pessoas contaminadas. Entretanto, em São Paulo, existia outra concepção sobre a transmissão e o extermínio de ratos era a principal medida. No Rio de Janeiro, alguns personagens, como Ismael da Rocha, defendiam a estratégia de São Paulo Com isso, foram estabelecidas duas redes, uma que concedia um papel aos ratos e outra não. A última foi vitoriosa até 1903. Naquela data, Oswaldo Cruz deu inicio a uma campanha de extermínio de ratos, que se mostrou eficaz. Quando os ratos passaram a ser considerados os culpados pela transmissão da doença mudanças ocorreram. As desinfecções passaram a se concentrar nesses animais e se planejou uma reformulação da cidade, com edifícios que vedassem a entrada de ratos e na construção de esgotos. / The present work discusses the socio-technical construction of the bubonic plague in Rio de Janeiro from 1897 to 1906. It has as theoretical support the actor-network theory and as methodology it follows Brazilian scientists, doctors and politicians in their action against the plague, analyzing the controversies in which they were involved and which socio-technical networks were mobilized by them. Sources used were: scientific papers published in Brazil-Medico, debates published in the daily press and reports from the General Direction of Public Health (Diretoria Geral de Saúde Pública DGSP). The main controversies were around the incubation time, lethality and method of transmission of the disease. Incubation affected directly the amount of days ships would be submitted to quarantine and the Federal Government believed that it lasted 20 days. However, pressure exerted by different actors, such as the Santos Commercial Association, were slowly changing this politic and also the understanding regarding the incubation period and the diseases lethality. In 1904, quarantines against the plague were extinguished from Brazil and it became a consensus that this disease wasnt very lethal and that the incubation time wasnt superior to 10 days. The matter of transmission implied different sanitary actions. In 1900, the Federal Government believed that the disease was transmitted through air or by objects, and therefore adopted actions such as house disinfection and isolation of contaminated people. However, in São Paulo, there was another conception regarding transmission, with the killing of rats being the main sanitary action. In Rio de Janeiro, some characters, such as Ismael da Rocha, were in favor of São Paulos initiative. Therefore, two networks were established, one where rats had an important part and another where they didnt. This last network was victorious until 1903. At that time, Oswaldo Cruz began a rat-killing campaign, which proved to be effective. When rats were considered as responsible for the transmission of the disease, different changes occurred. Disinfections became focused on this animals and a renovation of the city plan was done, with buildings that sealed the entrance of rats and the construction of sewers.

Orientador: Luís Guilherme de Oliveira / Coorientador: Samir Issa Samara / Banca: Hélio José Montassier / Banca: José Carlos Figueiredo Pantoja / Resumo: Os membros do gênero Pestivirus apresentam grande semelhança antigênica entre si. A reação sorológica cruzada entre o Vírus da Peste Suína Clássica (CSFV) e o Vírus da Diarreia Viral Bovina (BVDV) é de grande importância, e interfere em programas de erradicação da Peste Suína Clássica (PSC). Este trabalho teve como objetivos determinar a prevalência de anticorpos anti-BVDV em suínos de criações não tecnificadas, associar fatores de risco e buscar vínculos epidemiológicos entre rebanhos através do geoprocessaemento. Para tal, 360 amostras de soro de suínos provenientes de 56 propriedades rurais da região nordeste do Estado de São Paulo foram submetidas ao teste de virusneutralização (VN) utilizando os genótipos BVDV-1 estirpe Singer e BVDV-2 estirpe VS253. Foram detectados 4,72% (17) de amostras reagentes na VN, e 26,79% (15) rebanhos apresentaram pelo menos um animal reagente. Não foi possível associar fatores de risco. O estimador de intensidade de Kernel indicou áreas de alto risco de ocorrência da enfermidade e, juntamente com a análise de correspondência múltipla apontou associação com a presença de rebanhos de bovinos, quantidade mediana de leitões e rebanho suíno mediano nas propriedades da região. Ressalta-se a importância dos bovinos na ocorrência de infecções pelo BVDV em suínos, assim como a problemática no diagnóstico e levantamento epidemiológico para vigilância de PSC devido a presença de anticorpos anti-BVDV nos animais / Abstract: The members of the Pestivirus gender have great antigenic similarity. The serological cross-reaction between the Classical Swine Fever Virus (CSFV) and the Bovine Viral Diarrhea Virus (BVDV) usually interferes with Classical Swine Fever (CSF) eradications programs. This study focused on establishing the prevalence of antibodies for the BVDV in pigs of non-technified rearing farms, associate risk factors and use geospatial analysis tools to correlate positive herds. A set of 360 serum samples from 56 herds located in the northeastern region of the state of São Paulo were analyzed by the virusneutralization test (VN), using the genotypes BVDV-1 strain Singer and BVDV-2 strain VS253. During the sample collection, a questionnaire was applied to the farmers in order to obtain epidemiological information of the herd. 4,72% (17) of the samples were positive in the VN and 26,79% (15) of the herds had at least one positive animal. It was not possible to associate risk factors; however, the variable "use of milk serum in the feed" showed a tendency to be associated with the occurence of the disease. The Kernel intensity estimator showed three high risk of occurence areas, which were associated with the presence of bovine herds, medium quantity of piglets in the herd and medium size of total swine herd. The results highlight the importance of bovines in the prevalence of swine BVDV infections and the difficulties in diagnostic tests and CSF surveillance actions due to the serological cross-reaction between BVDV and CSFV antibodies / Mestre