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Studien har undersökt symptom samt hantering av PMS genom en enkätstudie där 72 kvinnor i åldrarna 18-49 deltagit. Syftet med studien var att beskriva symptombild och kvinnors sätt att hantera PMS. Fokus riktades mot vad kvinnorna gör för att hantera upplevda symptom och vi har tittat på olika samband. Resultaten visade att de allra flesta kvinnor upplever något PMS-symptom och förekomsten är hög (98,5%) med en spridd symptombild. Mest förekommande symptom när det gäller svåra besvär var ilska/lättretlighet, gråtmildhet och fysiska symptom. Det vanligaste sättet att hantera och förhålla sig till sin PMS i vår studie är ett medvetet och accepterande förhållningssätt. Att äta sötsaker, undvika sociala aktiviteter samt träna mindre har ett signifikant negativt samband med känslan av att kunna hantera sin PMS. Studien har även belyst att ökad medvetenhet hos kvinnor kan gynna deras förmåga att hantera PMS och föreslår fortsatt forskning inom området med fokus på behandlings metoder.

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Kyoto University (京都大学) / 0048 / 新制・課程博士 / 博士(工学) / 甲第16377号 / 工博第3458号 / 新制||工||1523(附属図書館) / 29008 / 京都大学大学院工学研究科都市社会工学専攻 / (主査)教授 小林 潔司, 教授 大津 宏康, 教授 河野 広隆 / 学位規則第4条第1項該当

abstract: United States Air Force airfield PAVER pavement management system enterprise data was reviewed for 67 networks. The distress survey extents and severity fields were joined with treatment costs estimated using RSMeans to determine the costliest distress. In asphalt surfaced pavements Longitudinal/transverse cracking, weathering, and block cracking resulted in the most pavement condition index (PCI) deducts while the costliest distresses are weathering, block cracking and longitudinal cracking. In portland cement concrete surfaced pavements linear cracking, joint seal damage, and joint spalling resulted in the most PCI deducts while the costliest distresses are joint seal damage, linear cracking, and corner spalling. The results of this data were then compared to airfield attributes: Pavement Temperature Group, Dominant American Association of State Highway and Transportation Officials (AASHTO) Soil Classification, Pavement- Transportation Computer Assisted Structural Engineering (PCASE) Climate Zone, and years since last maintenance. Maps showing the Pavement Temperature Group, Dominant AASHTO Soil Classification, and PCASE Climate Zone are included in Appendix A. Alligator cracking is most prevalent at the airfields with PTG 64-34 (Ellsworth, Fairchild, Hill, and Offutt) and 58-22 (Niagara and Vandenberg). Rutting is most prevalent at PTG 64-34 (Ellsworth, Fairchild, Hill, and Offutt). An increasing trend of joint spalling, corner spalling, and corner break with decreasing soil quality (AASHOTO A-1 to A-8 soils). The PCASE Climate Zone Cost Indices the cost index for weathering is approximately double in the moist region over the dry region. The cost index for block cracking is approximately double in the cold region over the hot region. It is recommended that the agency review its pavement performance modeling in the pavement management system to increase the recommendation of pavement preservation treatments and review the use of higher quality materials for pavement maintenance treatments. / Dissertation/Thesis / Masters Thesis Civil, Environmental and Sustainable Engineering 2020

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This thesis describes novel research using Portobello mushroom spores (PMS) as a biotemplate and reducing agent that may be used to produce nanocomposites and replicas with societal benefits. First, the use of PMS as a green eco-friendly bioreagent for the biosynthesis of Ag, Au and TiOx nanoparticles (NPs) and their hybrids is described. These have been characterised using SEM, TEM, XRD, FTIR, UV, SIMS, DLS and TGA (where a full list of acronyms is to be found on page iv). The spherical shape, location and mean diameter of the PMS-held (5-30nm) Ag and Au NPs were confirmed. PMS functional groups are comparable with those in plant sources and allow them to act as reducing/capping/stabilising agents. Second, the sequential biosynthesis of PMS-held Ca2+, CaCO3 and nanohydroxyapatite (nHAp) is described where surface nucleation and growth are facilitated by biotemplate surface hydrophilic polar groups (-OH and -COO-). XRD and HRTEM suggest that the nHAp so formed has lower crystallinity and greater directed growth in the (002) direction than commercial nHAp (e.g. Bio-Oss), making PMS-routes useful for the delivery of artificial bone (after subsequent PMS removal). Furthermore, PMS-held nHAp showed more rapid in-vitro mineralization in simulated body fluid (SBF). Third, it is shown that ascorbic acid (AA), haemoglobin (Hb) and insulin (In) can be loaded into/released by PMS through its cell walls faster than with synthetic hydrogels (PVA); the transdermal use of PMS nanocomposites is considered in the context of drug delivery nanotechnology, avoiding size-dependent toxicity. Fourth, it is shown by traditional diffusion and novel methods that the antimicrobial activity especially of Ag/PMS, but also TiOx/PMS and Ag-TiOx/PMS (but not Au/PMS) is good in the inhibition of the growth of E.coli and S.aureus bacteria. The highest activity of Ag/PMS is attributed to Agx+ release. Fifth, the synthesis of NPs/PMS and biomimetic TiOx/PMS has shown to lead to good photocatalysis for the removal of coloured organic pollutants (e.g. methyl orange) from water, with faster rates of removal in molecules/mg/s and turnover numbers (TON) (s-1) than commercial anatase-rutile TiO2 (P25) possibly as the texture of the titania replicas raises the number of multiple reflections of light.

There are few data available about the menstrual patterns of Australian teenagers and the prevalence of menstrual disorder in this age group. Aims To establish the typical experience of menstruation in a sample of 16-18 year old women attending ACT Secondary Colleges of Education. To determine the number of teenagers experiencing menstrual disorder that could require further investigation and management. Method The MDOT questionnaire was used to survey participants about their usual pattern of menstruation, signs and symptoms experienced with menses and how menstruation affected various aspects of their lives including school attendance, completion of school work, relationships, social, sexual and physical activity. Data analysis included exploration of aggregated data, as well as individual scrutiny of each questionnaire to determine menstrual disturbance requiring follow up. Those participants whose questionnaire indicated a requirement for further investigation, and who consented to being contacted, were followed up through an MDOT Clinic. Results One thousand and fifty one (1,05 1) completed questionnaires - 98% response rate. The typical experience of menstruation in the MDOT sample includes: bleeding patterns within normal parameters for this age group; menstrual pain, 94%; cramping pain, 71 %; symptoms associated with menstruation, 98.4%; PMS symptoms, 96%; mood disturbance before or during periods, 73%; school absence related to menstruation, 26%; high menstrual interference on one or more life activity, 55.8%; asymptomatic menstruation, 1 %; True response to 'My periods seem pretty normal' 7 1.4%. Statistically significant associations were found between each and all of: menstrual pain, symptoms, interference on life activities and school absence. The prevalence of significant menstrual disturbance in the sample is approximately 25% where: 2 1 % experienced severe pain; 26% reported school absence; 33% had seen a GP about periods; 26.9% think there is something wrong with periods; 23.5% require follow up based on individual scrutiny of each questionnaire; 10- 14% require further investigation to rule out endometriosis. Referral and investigation of menstrual pain, symptoms, and diagnosis of menstrual pathology in the sample was low. Conclusion The MDOT questionnaire has helped to establish a clearer picture of typical menstruation in the population sample. Where 1% of girls reported having asymptomatic menstruation, the majority of teenagers in the study reported menstrual pain and symptoms that could be experienced as part of the dysmenorrhoeic syndrome of symptoms, PMS, or underlying pathology such as endometriosis. Due to the overlap in symptoms and a propensity to be dismissive of menstrual pain and symptoms, many girls are suffering menstrual morbidities that could be well managed with NSAIDs and the oral contraceptive pill (OCP) if non-pathological, or investigated further if a menstrual pathology is suspected. Considering these results the reported school absence rate of 26% is not surprising. Whilst this study does not cost the true impact of menstrual disturbance on schooling, the results of the MDOT questionnaire reflect significant physical and emotional impact on a considerable number of teenager's lives which could also have repercussions on education, schooling performance and other areas of their lives. Future research is planned to determine the MDOT questionnaire's validity for identifying pathological menstrual disorder so it can act as a screening tool to facilitate earlier detection. Replication of the MDOT study should be done in younger teenagers (from menarche) to determine menstrual disturbance in the younger age group.