Although people meet products of the printing industry daily, they have very shallow knowledge of this sphere. In the theoretical part of this thesis, reader will be briefly acquainted with the printing and its history, focused mainly on the technology of the offset printing. The goal of this thesis is to create an interesting innovative design of offset printing machines in respect of all requirements in terms of ergonomics, safety and functionality of the device. The whole design procedure and its final result are presented in the practical part of thesis.

This diploma thesis deals with the optimized design solution and support housing proposal for a flexographic printing deck including the printing and anilox units. The support housing must be appropriately dimensioned to counteract the shock loads that occur during the printing process. At first, the thesis analyzes the impact load and the resulting size of loading forces. The support housing proposal is designed to resist these forces then.

Electrophysiological biosensors enables a novel way to measure electrical activity of biological structures both in-vitro and in-vivo and represents valuable alternative to current cellular activity measuring methods. Within this work we will be focusing on development of organic semiconductor (PEDOT:PSS) based Organic Electrochemical Transistors (OECTs) and optimization of material printing methods used in their development. These transistors are meant to be able to transfer electrochemical signals within the cell membrane to electrical signal. Such sensors should be used for cytotoxicity testing of chemicals and potential drugs on cardiomyocytes. Main benefits of OECTs are in their higher sensitivity thanks to their ability to locally amplify electric signals, better noise-signal ratio and outstanding biocompatibility. Their development is undemanding and inexpensive due material printing methods and materials processable at room temperatures.

The primary intention behind performing this thesis is to identify possibilities of implementing Metal Additive Manufacturing (MAM) in automotive industries in spare part manufacturing. This project tries to analyse the differences between conventional and contemporary manufacturing techniques. The industrial partner we worked with, Frauenthal Gnotec AB, specializes in traditional manufacturing techniques for making automobile spare parts primarily by stamping. Hence, a large building area is required to store the die and materials. Automobile spare parts are manufactured by demand. The organization has to have the die and material ready to go, forcing it to expand its inventories, workforce, and transportation, causing substantial financial liabilities.  The projects include a wide range of information from the different scientific articles, Journals, and consultations with AM services, Professors, and Technicians. The thesis studied the various available options in MAM and compared its specification with our client's requirements. The project estimates the cost, time for printing the components, thermo-mechanical properties, and structural properties of the component and its feasibility.   The project helped us put our theoretical knowledge about MAM into practice. It was very significant for us to have the opportunity to work with Frauenthal Gnotec AB, one of the leading automobile spare parts manufacturers in Sweden. Examine and evaluate their manufacturing and production strategies, which was very helpful for us in determining the efficacy of our efforts. Our scientific study, based on various simulations, optimizations, mechanical tests, and cost estimates, found MAM to be a promising future technology for the automotive industry.

Indiana University-Purdue University Indianapolis (IUPUI) / Acrylonitrile Butadiene Styrene (ABS) is the most widely used thermoplastics in 3D printing for making models, prototypes, patterns, tools and end-use parts. However, there is a lack of systematic understanding of the mechanical properties of 3D printed ABS components, including orientation-dependent tensile strength, creep, and fatigue properties. These mechanical properties are critically needed for design and application of 3D printed components. The main objective of this research is to systematically characterize key mechanical properties of 3D printed ABS components, including tensile, creep, and fatigue properties. Additionally, the eff ects of printing orientation on the mechanical prop- erties are investigated. There are two research approaches employed in the thesis: rst, experimental investigation of the tensile, creep, and fatigue properties of the 3D printed ABS components; second, laminate based finite-element modeling of tensile test to understand the stress distributions in different printing layers. The major conclusions of the thesis work are summarized as follows. The tensile test experiments show that the 0 printing orientation has the highest Young's modulus, 1.81 GPa, and ultimate strength, 224 MPa. The tensile test simulation shows a similar Young's modulus as the experiment in elastic region, indicating the robustness of laminate based finite element model. In the creep test, the 90 printing orientation has the lowest k value of 0.2 in the plastics creep model, suggesting the 90 is the most creep resistant among 0 , 45 , and 90 printing orientations. In the fatigue test, the average cycle number under load of 30 N is 3796 revolutions. The average cycle number decreases to 128 revolutions when the load is below 60N. Using the Paris Law, with the crack size of 0.75 mm long and stress intensity factor is varied from 352 to 700 MN -m^3/2 , the predicted fatigue crack growth rate is 0.0341 mm/cycle.

No description available.

No description available.

No description available.

No description available.

In the past decade, advances in tissue engineering have allowed researchers to fabricate simple tissues. However, the process of creating these native tissues is a time consuming and inefficient process. A scaffold must first be fabricated then exposed to a sea of cells in the hopes of seeding. Furthermore, even though cells may have attached, more time must be spent in order to allow the cells to migrate to their ideal locations. To deal with this problem, researchers have investigated whether rapid prototyping principals could be adapted to facilitate the cell seeding process by placing cells in their respective locations during scaffold fabrication. The goal for this thesis was to establish the foundation for a cell-compatible printer that, in the future, could fabricate pre-seeded scaffolds. This task included implementing changes to a commercial solenoid-based inkjet system that would allow cells to be loaded into the printer in a sterile fashion. In addition, protocols had to be designed with system limitations in mind. An initial test with the designed system showed a majority of cell viability percentages above 90%. If additional tests confirm this possibility, the system should be further modified to provide cells with a proper culturing environment. Furthermore, additional research would need to be performed in order to determine whether scaffolding materials can be dispensed through the system to fabricate scaffolds.