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  • About
  • The Global ETD Search service is a free service for researchers to find electronic theses and dissertations. This service is provided by the Networked Digital Library of Theses and Dissertations.
    Our metadata is collected from universities around the world. If you manage a university/consortium/country archive and want to be added, details can be found on the NDLTD website.
61

Insights into membrane binding of PROPPINs and Reconstitution of mammalian autophagic conjugation systems

Busse, Ricarda 08 January 2013 (has links)
No description available.
62

Two-phase Eulerian averaged formulation of entropy production for cavitation flow

Sun, Joseph 05 September 2014 (has links)
This research is focused on formulating a new model of entropy production for two-phase flow, including cavitating turbulent flow. In particular, it focuses on the following aspects of the fluid dynamics and the potential contribution of the model to fluid device design. It includes (i) developing a new turbulent entropy model, (ii) a new formula of entropy production rate for two-phase flow including cavitating turbulent flow based on the second law, (iii) applying the technique to study a NACA hydrofoil, and (iv) conducting associated performance analysis of a propeller using post-processing of the CFD results and demonstrating that entropy production of two-phase cavitating flow around the propeller can be correlated to the loss of power output. The first stage consists of formulating the entropy production for laminar channel flow using Gibb’s free energy. This model is validated through the analytically solved Navier-Stokes equations. Subsequently, the single-phase turbulent flow is formulated in a similar manner, but the validations are carried out by comparing the prediction of the model with DNS results. Then, the model of entropy production for two-phase turbulent flow is derived from Gibb’s equation and a version of the Reynolds averaged Navier-Stokes (RANS) equations. The k- ε model is employed to represent the turbulent properties of single phase and two phase flows. A developed inter-phase slip algorithm mixture model is applied to control over coupling of phases. The Rayleigh-Plesset equation is used to model the rate of mass generation of vapour at the inter phase. The standard k-ε turbulence equations are used to describe turbulence in the cavitation flow. The validations of CFD predictions include exploring the force and cavitation characteristics of the NACA 4412 hydrofoil section. The application of this entropy production model in engineering design is presented via the comparisons between CFD results and the experimental data for the velocity distributions behind propeller P5168.
63

A general methodology for generating representative load cycles for monohull surface vessels

Truelove, William Anthony Lawrence 19 December 2018 (has links)
In this thesis, a general methodology for generating representative load cycles for arbitrary monohull surface vessels is developed. The proposed methodology takes a hull geometry and propeller placement, vessel loading condition, vessel mission, and weather data (wind, waves, currents) and, from that, generates the propeller states (torque, speed, power) and steering gear states (torque, speed, power) necessary to accomplish the given mission. The propeller states, together with the steering gear states, thus define the load cycle corresponding to the given inputs (vessel, mission, weather). Some key aspects of the proposed methodology include the use of a surge-sway-yaw model for vessel dynamics as well as the use of surrogate geometries for both the hull and propeller(s). What results is a methodology that is lean (that is, it requires only sparse input), fast, easy to generalize, and reasonably accurate. The proposed methodology is validated by way of two separate case studies, case A and case B (both involving distinct car-deck ferries), with case A being a more ideal case, and case B being a less ideal case given the methodology proposed. In both cases, the load cycle generation process completed in greater than real time, achieving time ratios (simulated time to execution time) of 3.3:1 and 12.8:1 for cases A and B respectively. The generated propeller and steering gear states were then compared to data collected either at sea or from the vessels' documentation. For case A, the propeller speed, torque, and power values generated were all accurate to within +/- 3%, +/- 7%, and +/- 10% of the true values, respectively, while cruising, and accurate to within +/- 14%, +/- 36%, and +/- 42% of the true values, respectively, while maneuvering. In addition, the steering gear powers generated in case A were consistent with the capabilities of the equipment actually installed on board. For case B, the propeller speed, torque, and power values generated were all accurate to within +/- 2%, +/- 8%, and +/- 9% of the true values, respectively, while cruising, and accurate to within +/- 28%, +/- 45%, and +/- 66% of the true values, respectively, while maneuvering. In case B, however, the steering gear powers generated were questionable. Considering the results of the validation, together with the rapid process runtimes achieved and sparse inputs given, one may conclude that the methodology proposed in this thesis shows promise in terms of being able to generate representative load cycles for arbitrary monohull surface vessels. / Graduate
64

Design of Miniaturized Underwater Vehicle with Propulsions for Deep-sea Research Applications

January 2014 (has links)
abstract: The ocean is vital to the health of our planet but remains virtually unexplored. Many researchers seek to understand a wide range of geological and biological phenomena by developing technologies which enable exploration of the deep-sea. The task of developing a technology which can withstand extreme pressure and temperature gradients in the deep ocean is not trivial. Of these technologies, underwater vehicles were developed to study the deep ocean, but remain large and expensive to manufacture. I am proposing the development of cost efficient miniaturized underwater vehicle (mUV) with propulsion systems to carry small measurement devices and enable deep-sea exploration. These mUV's overall size is optimized based on the vehicle parameters such as energy density, desired velocity, swimming time and propulsion performance. However, there are limitations associated with the size of the mUV which leads to certain challenges. For example, 2000 m below the sea level, the pressure is as high as 3000 psi. Therefore, certain underwater vehicle modules, such as the propulsion system, will require pressure housing to ensure the functionality of the thrust generation. In the case of a mUV swimming against the deep-sea current, a thrust magnitude is required to enable the vehicle to overcome the ocean current speed and move forward. Therefore, the size of the mUV is limited by the energy density and the propeller size. An equation is derived to miniaturize underwater vehicle while performing with a certain specifications. An inrunner three-phase permanent magnet brushless DC motor is designed and fabricated with a specific size to fit inside the mUV's core. The motor is composed of stator winding in a pressure housing and an open to water ring-propeller rotor magnet. Several ring-propellers are 3D printed and tested experimentally to determine their performances and efficiencies. A planer motion optimal trajectory for the mUV is determined to minimize the energy usage. Those studies enable the design of size optimized underwater vehicle with propulsion to carry small measurement sensors and enable underwater exploration. Developing mUV's will enable ocean exploration that can lead to significant scientific discoveries and breakthroughs that will solve current world health and environmental problems. / Dissertation/Thesis / Doctoral Dissertation Mechanical Engineering 2014
65

Simulação da interação casco-propulsor de uma embarcação usando mecânica dos fluidos computacional (CFD). / Simulation of the propeller-hull interaction using computational fluid mechanics (CFD).

Carlos José Rocha de Oliveira Castro 13 February 2007 (has links)
Este trabalho discute a questão da interação entre o casco do navio e o propulsor em funcionamento conjunto, e sua simulação por ferramentas computacionais. O texto se concentra em descrever os principais efeitos dessa interação, as principais dificuldades em se estimar esses efeitos, os métodos tradicionalmente usados, e como ferramentas computacionais podem ser aplicadas de maneira vantajosa. No texto também pode ser encontrada uma análise crítica dos métodos mais comuns e dos resultados, baseada em trabalhos de diversos autores, publicados nacional e internacionalmente. É apresentado o método dos volumes finitos, usado nesta pesquisa, algumas de suas particularidades principais, vantagens e desvantagens, e os resultados das simulações realizadas, interpretados à luz dos valores experimentais usados para comparação e das limitações do método dos Volumes Finitos. A comparação é feita analisando-se grandezas integrais, como a resistência do casco ou o empuxo do propulsor; e também as características do escoamento, como o perfil de velocidade na esteira, presença de vórtices, e outras estruturas típicas. Os resultados obtidos têm a mesma ordem de precisão dos que tem sido obtidos por outros pesquisadores, internacionalmente, e são coerentes qualitativamente; mas algumas questões referentes aos modelos físico e numérico escolhidos ainda limitam a precisão dos resultados e restringem sua adoção em atividades de engenharia. Entretanto, diversas características observadas no escoamento contribuem para aumentar o conhecimento de alguns fenômenos envolvidos no problema. / This work is about the hull and propeller interaction in joint functioning, and its simulation by computational tools. The text concentrates in describing the main effects of such interaction, the main difficulties in the estimation of these effects, the methods traditionally adopted, and how computational tools can be applied in advantageous way. A critical analysis of the most common methods and results, based on paperworks of several different authors worldwide, can also be found. The Finite Volumes method, used in this research, is presented - its main issues, advantages and disadvantages, and the simulations outcomes, compared to the experimental values and explained by the knowledge of the Finite Volumes method limitations. The comparison is made by means of both integral values, such as the hull\'s resistance or the propeller thrust; as well as the characteristics of the flow, like the wake velocity profile, presence of vortex, and other typical structures. The results shows the same error band than the ones which has been obtained by other researchers, worldwide, and most of the typical characteristics of the flow were observed. But some issues concerned to the chosen physical and numerical models still limit the precision of the outcomes, and restrict the application of such models at engineering activities. But several insights about the flow, obtained at this study, can be useful to the understanding of some phenomena involved in the propeller operation.
66

A CFD Analysis of Cyclodial Propellers

Thelin, Fredrik January 2017 (has links)
The quest for more efficient machines is always ongoing in the engineering world. This project is no different. ABB are investigating a new type of propeller that seems to offer increased efficiency compared to normal screw propellers. That is a so called foil wheel propeller. The foil move in a circular pattern with the fluid stream moving in the radial direction of the propeller instead of the axial as in a screw propeller. If the propeller is placed and modeled correctly it can also be used as a thrust vectoring device. This report focuses on the fluid physics of the foil wheel propeller, or as it is called in this report radial flow propeller. First of all the movements and interactions of the blades must be understood. Both to keep the efficiency high to compete with screw propellers, but also to foresee any problems that may occur with such a new device. A scaled down version of the propeller have been commissioned by ABB and will be tested in some time after the work within this report is completed. The effects associated to this will also be analyzed. The tool to compute the flow physics of the radial flow propeller will be computational fluid dynamics. Computational fluid dynamics uses a numerical method to compute the entire fluid field in space and time. The flow around the propeller is highly complex so a detailed analysis is needed if a well functioning control system is to be constructed for instance. The differences between the downscale and the full-scale are great, even when the non dimensional coefficients are considered. The down-scale case will be less efficient, it will be difficulties predicting the performance of the full-scale since the downscale flow is much less powerful than the full-scale case. The interaction between the blades has a large effect. There is a strong relation between angle of attack and the number of blades. The forces that are large change by about 30\% so it must definitely be considered if a model is to be used for a control system.
67

Flow regimes and instabilities of propeller crashback

Pontarelli, Matthew 01 August 2017 (has links)
Crashback operation of a propeller is a common emergency slowing maneuver for ships and submarines. The reversing of the propeller while the vessel is moving forward results in large loads on the propeller blades and highly detached flow, which presents both practical concerns and fundamental fluid physics inquiries. This thesis contains a comprehensive numerical analysis of two propellers in crashback operation. Available numerical and experimental data for David Taylor Model Basin (DTMB) 4381 propeller are used for validation of the computational fluid dynamics solver used, REX. A second propeller, Maritime Research Institute Netherlands (MARIN) 7371R is used to classify the common crashback flow behavior into regimes. Four regimes were identified, each existing for a range of operating conditions. The most prominent and deciding feature of the flow regimes is the presence of a ring vortex, resulting from the opposing action of the free-stream flow and the propeller induced flow. The position, shape and strength changes between regimes, dominating the dynamics of the flow by altering the induced flow into the propeller disk. Flow conditions resulting from regime transitions are described. Changes in the ring vortex structure lead to two stable flow conditions of interest. One condition produces a reduction of thrust despite the increase in flow speed into the propeller and negligible side-forces. The other condition creates large side-forces capable of rotating a vessel, resulting from an asymmetry forming in the ring vortex. Additionally, massive flow separation occurs at high free-stream speeds that cause extreme blade loading. An extensive description of each flow regime is provided, with further investigation and discussion of the flow regimes that present more practical concerns and novel characteristics of the crashback flow.
68

Predicting cavitation-induced noise from marine propellers

McIntyre, Duncan 12 January 2021 (has links)
Noise pollution threatens marine ecosystems, where animals rely heavily on sound for navigation and communication. The largest source of underwater noise from human activity is shipping, and propeller-induced cavitation is the dominant source of noise from ships. Mitigation strategies require accurate methods for predicting cavitation-induced noise, which remains challenging. The present thesis explores prediction and modelling strategies for cavitation-induced noise from marine propellers, and provides insight into models that can be used both during propeller design and to generate intelligent vessel control strategies. I examined three distinct approaches to predicting cavitation-induced noise, each of which is discussed in one of the three main chapters of this thesis: a high-fidelity computational fluid dynamics scheme, a parametric mapping procedure, and the use of field measurements. Each of these three chapters presents different insight into the acoustic behaviour of cavitating marine propellers, as well both real and potential strategies for mitigating this critical environmental emission. A combined experimental and numerical study of noise from a cavitating propeller, focused on both the fundamental importance of experimental findings and the effectiveness of the numerical modelling strategy used, is detailed in the first main chapter of this thesis. The experimental results highlighted that loud cavitation noise is not necessarily associated with high-power or high-speed propeller operation, affirming the need for intelligent vessel operation strategies to mitigate underwater noise pollution. Comparison of the experimental measurements and simulations revealed that the simulation strategy resulted in an over-prediction of sound levels from cavitation. Analysis of the numerical results and experiments strongly suggested that the cavitation model implemented in the simulations, a model commonly used for marine propeller simulations, was responsible for the over-prediction of sound levels. Ships are powered primarily by combustion engines, for which it is possible to generate "maps" relating the emission of pollutants to the engine’s speed and torque; the second main chapter of this thesis presents the methodology I developed for generating similar "maps" relating the level of cavitation-induced noise to the speed and torque of a ship's propeller. A proof-of-concept of the method that used the model propeller from the first main chapter is presented. To generate the maps, I used a low-order simulation technique to predict the cavitation induced by the propeller at a range of different speed and torque combinations. A pair of semi-empirical models found in the literature were combined to provide the framework for predicting noise based on cavitation patterns. The proof-of-concept map shows a clear optimal operating regime for the propeller. The final main chapter of this thesis presents an analysis of field noise measurements of coastal ferries in commercial operation, the data for which were provided by an industrial partner. The key finding was the identification of cavitation regime changes with variation in vessel speed by their acoustic signatures. The results provide a basis for remotely determining which vessels produce less noise pollution when subject to speed limits, which have been implement in critical marine habitats, and which vessels produce less noise at a specific optimum speed. / Graduate
69

Transtibiální protéza pro rekreační plavání / Transtibial prosthesis for recreational swimming

Křemen, Jan January 2014 (has links)
This thesis deals with the construction of an active transtibial prosthesis for recreational swimming. Its aim is to create a working sample of such a prosthesis. The device will primarily serve the patient to move in water - it will be attached to the stump and it will be driven forward. Secondarily, the prosthesis can be used for walking, in the sense that the patient attaches the prosthesis near to a water surface (pool, lake, ocean) and comes with it to the shore. As part of the design and electronics it will be necessary to determine the characteristics of the human resistance in water depending on speed and to determine the necessary propulsion (thrust) strength of the propeller, which will serve as the driving force. Subsequently there will be formed structural variants and selected the best one. This will become default for design and construction of simplified testing device, which will be tested for static thrust. After verifying the functionality and reliability, the final functional sample will be manufactured and tested too.
70

The Role of the Cytosolic Chaperonin CCT in Folding β-Propeller Proteins

Ludlam, William Grant 14 June 2021 (has links)
Many Proteins require the aid of molecular chaperones to achieve a stable folding state and avoid misfolding pathologies. A major eukaryotic chaperone is the cytosolic chaperonin CCT. While CCT is known to fold a significant portion of all cytosolic proteins, there is no general model for the mechanism CCT uses to fold substrate proteins. One class of proteins that CCT is known to fold are β-propeller containing proteins. Here, we present structural and biochemical data on the processes that CCT uses to fold three distinct β-propeller proteins: the G-protein Beta 5 (Gβ5) subunit of the Gβ5-RGS complex, mLST8 of the mTOR complexes, and BBS2, 7, and 9 of the BBSome. We also explore the mechanisms by which these proteins are assembled into their respective signaling complexes after being folded by CCT. We found that each CCT substrate follows a unique folding trajectory and posit that the major determinants underlying each trajectory are governed by interactions between the substrate and CCT and interactions with downstream binding partners.

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