A associação entre epilepsia e transtornos psicóticos é amplamente relatada na literatura. Características clínicas e do seu impacto, tais como suicídio, tentativas de suicídio, homicídio e alterações cognitivas são evidenciados em poucos estudos que associam epilepsia e psicose. Este estudo comparou o impacto clínico e funcionamento psicossocial dos pacientes com epilepsia e transtornos psicóticos, analisando ainda as diferenças entre pacientes com psicose interictal e pós-ictal. O estudo consiste de uma revisão de prontuário de todos os pacientes atendidos no PRONEPSI com epilepsia e transtornos mentais. Foram estudados 143 indivíduos, divididos em dois grupos: 82 pacientes com diagnóstico de epilepsia e transtornos psicóticos e 61 pacientes com epilepsia e outro transtorno mental. O grupo de pacientes psicóticos foi estudado comparando dados entre pacientes com psicose interictal (53) e pós-ictal (17). O grupo de pacientes com transtornos psicóticos apresentou menor escolaridade, mais história familiar de psicose, maior número de tentativas de homicídio, mais estados de mal epiléptico, mais internações psiquiátricas, história pregressa de insulto ao SNC e retardo mental. Além disso, a epilepsia foi considerada um fator causal importante para desenvolvimento da psicose. O grupo de pacientes com transtornos psicóticos também se diferenciou, revelando maior impacto na esfera cognitiva, vocacional e pessoal. Os pacientes com psicose interictal tiveram mais história familiar para psicose e a epilepsia foi considerada um fator causal importante para seu desenvolvimento. Pacientes com epilepsia e transtornos psicóticos apresentam um maior comprometimento clínico geral o que interfere diretamente no seu comprometimento funcional e na gravidade do impacto. Os pacientes com epilepsias mais graves e algum tipo de insulto ao SNC parecem ser mais vulneráveis ao desenvolvimento de transtornos psicóticos em comparação aos pacientes com formas menos graves de epilepsia / The association between epilepsy and psychotic disorders has been well documented in literature. Although this association is well-known, few studies regarding psychosis and epilepsy investigated the clinical characteristics of these patients and its impact on psychosocial function, suicide and suicide attempts, homicide attempts and cognitive deficits. The aim of this chart review was to compare the clinical impact and the psychosocial function between patients with epilepsy and psychotic disorders and patients with epilepsy and other psychiatric disorders. We also compared the clinical characteristics and psychosocial function between patients with postictal psychosis and interictal psychosis. We reviewed 143 charts, divided in two groups: 82 charts of patients with epilepsy and psychotic disorders and 61 charts of patients with epilepsy and other psychiatric disorders. In the group of patients with epilepsy and psychosis, 53 had a diagnosis of interictal psychosis and 17 of postictal psychosis. Patients with psychotic disorders had fewer years of education, more family history of psychotic disorders and higher number of homicide attempts, status epilepticus, psychiatric admissions and history of central nervous system insults. They also presented more impact on cognitive, vocational and interpersonal scales. Epilepsy was considered a major cause to the development of psychosis. Regarding the differences between patients with interictal and postictal psychosis, the only difference found was that the patients with interictal psychosis presented more family history of psychosis. Also, in both groups epilepsy was considered a major cause to the development of psychosis. Patients with psychotic disorders had a more severe clinical impairment in comparison with patients with other psychiatric disorders, which may have interfered in psychosocial functioning and severity of impact. Patients with central nervous system\'s insults and severe epilepsy may be likely more prone to psychosis\'s development than other patients with less severe forms of epilepsy

A associação entre epilepsia e transtornos psicóticos é amplamente relatada na literatura. Características clínicas e do seu impacto, tais como suicídio, tentativas de suicídio, homicídio e alterações cognitivas são evidenciados em poucos estudos que associam epilepsia e psicose. Este estudo comparou o impacto clínico e funcionamento psicossocial dos pacientes com epilepsia e transtornos psicóticos, analisando ainda as diferenças entre pacientes com psicose interictal e pós-ictal. O estudo consiste de uma revisão de prontuário de todos os pacientes atendidos no PRONEPSI com epilepsia e transtornos mentais. Foram estudados 143 indivíduos, divididos em dois grupos: 82 pacientes com diagnóstico de epilepsia e transtornos psicóticos e 61 pacientes com epilepsia e outro transtorno mental. O grupo de pacientes psicóticos foi estudado comparando dados entre pacientes com psicose interictal (53) e pós-ictal (17). O grupo de pacientes com transtornos psicóticos apresentou menor escolaridade, mais história familiar de psicose, maior número de tentativas de homicídio, mais estados de mal epiléptico, mais internações psiquiátricas, história pregressa de insulto ao SNC e retardo mental. Além disso, a epilepsia foi considerada um fator causal importante para desenvolvimento da psicose. O grupo de pacientes com transtornos psicóticos também se diferenciou, revelando maior impacto na esfera cognitiva, vocacional e pessoal. Os pacientes com psicose interictal tiveram mais história familiar para psicose e a epilepsia foi considerada um fator causal importante para seu desenvolvimento. Pacientes com epilepsia e transtornos psicóticos apresentam um maior comprometimento clínico geral o que interfere diretamente no seu comprometimento funcional e na gravidade do impacto. Os pacientes com epilepsias mais graves e algum tipo de insulto ao SNC parecem ser mais vulneráveis ao desenvolvimento de transtornos psicóticos em comparação aos pacientes com formas menos graves de epilepsia / The association between epilepsy and psychotic disorders has been well documented in literature. Although this association is well-known, few studies regarding psychosis and epilepsy investigated the clinical characteristics of these patients and its impact on psychosocial function, suicide and suicide attempts, homicide attempts and cognitive deficits. The aim of this chart review was to compare the clinical impact and the psychosocial function between patients with epilepsy and psychotic disorders and patients with epilepsy and other psychiatric disorders. We also compared the clinical characteristics and psychosocial function between patients with postictal psychosis and interictal psychosis. We reviewed 143 charts, divided in two groups: 82 charts of patients with epilepsy and psychotic disorders and 61 charts of patients with epilepsy and other psychiatric disorders. In the group of patients with epilepsy and psychosis, 53 had a diagnosis of interictal psychosis and 17 of postictal psychosis. Patients with psychotic disorders had fewer years of education, more family history of psychotic disorders and higher number of homicide attempts, status epilepticus, psychiatric admissions and history of central nervous system insults. They also presented more impact on cognitive, vocational and interpersonal scales. Epilepsy was considered a major cause to the development of psychosis. Regarding the differences between patients with interictal and postictal psychosis, the only difference found was that the patients with interictal psychosis presented more family history of psychosis. Also, in both groups epilepsy was considered a major cause to the development of psychosis. Patients with psychotic disorders had a more severe clinical impairment in comparison with patients with other psychiatric disorders, which may have interfered in psychosocial functioning and severity of impact. Patients with central nervous system\'s insults and severe epilepsy may be likely more prone to psychosis\'s development than other patients with less severe forms of epilepsy

Lam, Yin Hung. / Thesis (M.Phil.)--Chinese University of Hong Kong, 2010. / Includes bibliographical references (p. 89-97). / Abstracts in English and Chinese. / ABSTRACT --- p.iii / 摘要(ABSTRACT IN CHINESE) --- p.iv / ACKNOWLEDGEMENTS --- p.v / TABLE OF CONTENTS --- p.vi / TlST OF TABLES --- p.viii / LIST OF FIGURES --- p.ix / LIST OF APPENDIX --- p.x / Chapter CHAPTER I: --- INTRODUCTION --- p.1 / PSYCHOTIC DISORDERS --- p.1 / EXPRESSED EMOTION & RELAPSE OF PSYCHOTIC DISORDERS --- p.2 / POSITIVE EXPRESSED EMOTION COMPONENTS --- p.3 / ASSESSMENT TOOLS OF EXPRESSED EMOTION --- p.5 / CULTURAL CONSIDERATIONS OF EXPRESSED EMOTION --- p.7 / PSYCHOSOCIAL WELL-BEING OF PPD --- p.10 / RECOVERY: EMPOWERMENT & LIFE SATISFACTION --- p.11 / EMPOWERMENT --- p.13 / LIFE SATISFACTION --- p.14 / PSYCHOSOCIAL WELL-BEING OF RELATIVES --- p.14 / AIMS OF STUDY --- p.15 / HYPOTHESES OF STUDY --- p.16 / Chapter CHAPTER II: --- METHOD --- p.17 / PARTICIPANTS --- p.17 / MEASURES --- p.21 / PROCEDURE --- p.33 / Chapter CHAPTER III: --- RESULTS --- p.33 / INTER-RATER RELIABILITY OF FMSS CATEGORIZATIONS --- p.33 / NEGATIVE AND POSITIVE EE SCORES --- p.34 / RELATIONSHIP BETWEEN OVERALL EE AND SUB-EE --- p.36 / RELATIONSHIP BETWEEN FMSS AND SELF-REPORT MEASURES --- p.38 / "RELATIONSHIP BEWTEEN DEMOGRAPHIC CHARACTERISTICS, SELF-REPORT EE AND OUTCOME VARIABLES" --- p.39 / RELATIVES' EE: BREAKDOWN BY DEMOGRAPHIC CHARACTERISTICS --- p.43 / COVARIATES RELATED TO PPD´بS LIFE SATISFACTION CONTROLLED FOR --- p.47 / RELATIONSHIP BETWEEN RELATIVES´ة EXPRESSED EMOTION AND PSYCHOSOCIAL WELL-BEING OF RELATIVES AND PPD --- p.49 / PROPOSED MODEL (MODEL 1): SELF-REPORT AND FMSS --- p.49 / REFINED MODEL (MODEL 2): SELF-REPORT AND FMSS --- p.52 / FINAL MODEL (MODEL 3 A): SELF-REPORT AND FMSS --- p.56 / ALTERNATIVE MODEL (MODEL 3B): SELF-REPORT AND FMSS --- p.61 / Chapter CHAPTER IV: --- DISCUSSION --- p.67 / EXPRESSED EMOTION --- p.68 / SCORING SCHEME FOR EE --- p.68 / FMSS EE CATEGORIZATION --- p.68 / FMSS & SELF-REPORT OVERALL & SUB-EE --- p.69 / RELATIONSHIP BETWEEN FMSS & SELF-REPORT EE --- p.71 / "RELATIONSHIP BETWEEN DEMOGRAPHICS, SELF-REPORT EE & OUTCOME VARIABLES" --- p.71 / COVARIATES RELATED TO PPD，S LIFE SATISFACTION --- p.73 / "RELATIONSHIP BETWEEN RELATIVES, EE AND PSYCHOSOCIAL WELL-BEING OF RELATIVES & PPD" --- p.74 / OVERALL COMPARISON BETWEEN FMSS & SELF-REPORT MODELS --- p.78 / IMPLICATIONS --- p.79 / LIMITATIONS OF THE STUDY AND FUTURE DIRECTION --- p.82 / REFERENCES --- p.89

<p>The aim of this thesis was to critically examine the current use of the Camberwell Assessment of Need (CAN) in outcome assessment for service evaluation. A further aim was to propose a metric for assessing the adequacy of community mental health services in meeting ongoing needs over longer stretches of time.</p><p>We made four prospective follow-up studies of CAN assessments of patients with severe mental illness in community-based mental health care.</p><p>A factor analysis (n=741) gave support for a three-factor model, comprising only 60% of the CAN items. Need assessments (n= 92) in 1997 and 2003 were compared at both the summed total and the underlying item levels of the CAN. The mean total scores did not change, yet there were significant changes in the underlying items. Changes in mean number of needs between 1997 and 1999 were measured (n=262) with both total scores, summed over all CAN items, and with sub-total scores, summed over two sets of items reflecting the social services and the psychiatric services respectively. As indicated by the sub-total scores, all significant changes occurred within the psychiatric services, a result not possible to discern from the total scores. The Met Needs Index (MNI), defined by us as the aggregate measure of beneficial outcome, indicated that needs in general were met during 71% of the intervals between the annuals assessments from 1997 through 2004. However, the variation among particular items was large.</p><p>In conclusion, the summary scores typically used as outcome measures are likely to conceal meaningful variation at the item level. Nevertheless, sub-total scores, being more transparent, might be more useful in outcome assessment. The MNI is a continuous, normally distributed metric, estimable over any number of consecutive assessments, which seems suitable for assessing the achieved benefit of services for patients with long-term ongoing needs.</p>

The aim of this thesis was to critically examine the current use of the Camberwell Assessment of Need (CAN) in outcome assessment for service evaluation. A further aim was to propose a metric for assessing the adequacy of community mental health services in meeting ongoing needs over longer stretches of time. We made four prospective follow-up studies of CAN assessments of patients with severe mental illness in community-based mental health care. A factor analysis (n=741) gave support for a three-factor model, comprising only 60% of the CAN items. Need assessments (n= 92) in 1997 and 2003 were compared at both the summed total and the underlying item levels of the CAN. The mean total scores did not change, yet there were significant changes in the underlying items. Changes in mean number of needs between 1997 and 1999 were measured (n=262) with both total scores, summed over all CAN items, and with sub-total scores, summed over two sets of items reflecting the social services and the psychiatric services respectively. As indicated by the sub-total scores, all significant changes occurred within the psychiatric services, a result not possible to discern from the total scores. The Met Needs Index (MNI), defined by us as the aggregate measure of beneficial outcome, indicated that needs in general were met during 71% of the intervals between the annuals assessments from 1997 through 2004. However, the variation among particular items was large. In conclusion, the summary scores typically used as outcome measures are likely to conceal meaningful variation at the item level. Nevertheless, sub-total scores, being more transparent, might be more useful in outcome assessment. The MNI is a continuous, normally distributed metric, estimable over any number of consecutive assessments, which seems suitable for assessing the achieved benefit of services for patients with long-term ongoing needs.

Background The base rate of transition from subthreshold psychotic experiences (the exposure) to clinical psychotic disorder (the outcome) in unselected, representative and non-help-seeking population-based samples is unknown. Method A systematic review and meta-analysis was conducted of representative, longitudinal population-based cohorts with baseline assessment of subthreshold psychotic experiences and follow-up assessment of psychotic and non-psychotic clinical outcomes. Results Six cohorts were identified with a 3–24-year follow-up of baseline subthreshold self-reported psychotic experiences. The yearly risk of conversion to a clinical psychotic outcome in exposed individuals (0.56%) was 3.5 times higher than for individuals without psychotic experiences (0.16%) and there was meta-analytic evidence of dose–response with severity/persistence of psychotic experiences. Individual studies also suggest a role for motivational impairment and social dysfunction. The evidence for conversion to non-psychotic outcome was weaker, although findings were similar in direction. Conclusions Subthreshold self-reported psychotic experiences in epidemiological non-help-seeking samples index psychometric risk for psychotic disorder, with strong modifier effects of severity/persistence. These data can serve as the population reference for selected and variable samples of help-seeking individuals at ultra-high risk, for whom much higher transition rates have been indicated.

Thesis (Ph.D.)--University of Alabama at Birmingham, 2008. / Title from first page of PDF file (viewed on June 24, 2009). Includes bibliographical references (p. 108-133).

Computational modelling has been gaining an increasing amount of support from the neuroscience community as a tool to assay cognition and computational processes in the brain. Lately, scientists have started to apply computational methods from neuroscience to the study of psychiatry to gain further insight into the mechanisms leading to mental disorders. In fact, only recently has psychiatry started to move away from categorising illnesses using behavioural symptoms in an attempt for a more biologically driven diagnosis. To date, several neurobiological anomalies have been found in schizophrenia and led to a multitude of conceptual framework attempting to link the biology to the patients’ symptoms. Computational modelling can be applied to formalise these conceptual frameworks in an effort to test the validity or likelihood of each hypothesis. Recently, a novel conceptual model has been proposed to describe how positive symptoms (delusions, hallucinations and thought disorder) and cognitive symptoms (poor decision-making, i.e. “executive functioning”) might arise in schizophrenia. This framework however, has not been tested experimentally or against computational models. The focus of this thesis was to use a combination of behavioural experiments and computational models to independently assess the validity of each component that make up this framework. The first study of this thesis focused on the computational analysis of a disrupted prediction-error signalling and its implications for decision-making performances in complex tasks. Briefly, we used a reinforcement-learning model of a gambling task in rodents and disrupted the prediction-error signal known to be critical for learning. We found that this disruption can account for poor performances in decision-making due to an incorrect acquisition of the model of the world. This study illustrates how disruptions in prediction-error signalling (known to be present in schizophrenia) can lead to the acquisition of an incorrect world model which can lead to poor executive functioning or false beliefs (delusions) as seen in patients. The second study presented in this thesis addressed spatial working memory performances in chronic schizophrenia, bipolar disorder, first episode psychosis and family relatives of DISC1 translocation carriers. We build a probabilistic inference model to solve the working memory task optimally and then implemented various alterations of this model to test commonly debated hypotheses of cognitive deficiency in schizophrenia. Our goal was to find which of these hypotheses accounts best for the poor performance observed in patients. We found that while the performance at the task was significantly different for most patients groups in comparison to controls, this effect disappeared after controlling for IQ in one group. The models were nonetheless fitted to the experimental data and suggest that working memory maintenance is most likely to account for the poor performances observed in patients. We propose that the maintenance of information in working memory might have indirect implications for measures of general cognitive performance, as these rely on a correct filtering of information against distractions and cortical noise. Finally the third study presented in this thesis assessed the performance of medicated chronic schizophrenia patients in a statistical learning task of visual stimuli and measured how the acquired statistics influenced their perception. We find that patient with chronic schizophrenia appear to be unimpaired at statistical learning of visual stimuli. The acquired statistics however appear to induce less expectation-driven ‘hallucinations’ of the stimuli in the patients group than in controls. We find that this is in line with previous literature showing that patients are less susceptible to expectation-driven illusions than controls. This study highlights however the idea that perceptual processes during sensory integration diverge from this of healthy controls. In conclusion, this thesis suggests that impairments in reinforcement learning and Bayesian inference appear to be able to account for the positive and cognitive symptoms observed in schizophrenia, but that further work is required to merge these findings. Specifically, while our studies addressed individual components such as associative learning, working memory, implicit learning & perceptual inference, we cannot conclude that deficits of reinforcement learning and Bayesian inference can collectively account for symptoms in schizophrenia. We argue however that the studies presented in this thesis provided evidence that impairments of reinforcement learning and Bayesian inference are compatible with the emergence of positive and cognitive symptoms in schizophrenia.

A maioria dos estudos sobre o papel da família na continuidade do tratamento após o primeiro episódio psicótico investigam os casos de abandono de tratamento e apontam para aspectos \"negativos da família\". Poucos estudos investigam o papel da família nos casos de pacientes que se mantém no tratamento. Objetivo: Compreender a experiência de cuidar de um familiar no PEP e evidenciar as motivações para manter-se no cuidado. Método: Trata-se de pesquisa qualitativa que utilizou a teoria sistêmica familiar como referencial teórico e a narrativa como referencial metodológico. Foram entrevistados 13 familiares cuidadores de 12 pacientes. Para a realização das entrevistas em profundidade com enfoque narrativo foi utilizada a seguinte questão norteadora: Nós sabemos que poucos familiares se mantêm no tratamento em saúde mental junto ao seu jovem familiar adoecido após o primeiro episódio psicótico. Se manter no tratamento conjuntamente ao paciente e cuidar do mesmo é chamado por nós de engajamento. São ações como levar nas consultas, administrar a medicação, modo de se relacionar, cuidar da higiene e assim por diante. Sendo assim, gostaríamos que você nos contasse sobre o que te motiva a permanecer cuidando e tudo que você e sua família fazem pelo seu familiar adoecido. Para a exploração das narrativas foi utilizada a técnica de análise de conteúdo indutiva. Resultados: A análise das narrativas definiu o engajamento familiar em três grandes categorias interdependentes. Uma é relacionada ao contexto de sentimentos envolvidos no cuidar denominada \"Motivações para o engajamento\", as outras duas referem-se às ações relacionadas ao cuidar denominadas \"As ações de engajamento\" e \"Avaliação constante do cuidar\". Conclusão: A pesquisa contribui com o conhecimento ao apresentar famílias ativamente envolvidas no cuidado com o jovem em tratamento para o primeiro episódio psicótico. O referencial teórico - metodológico possibilitou destacar e valorizar as histórias, experiências e as relações familiares envolvidos no cuidado de um ente querido. Os cuidados foram descritos e contextualizados nos valores culturais das famílias. Verificamos que os familiares percebem o cuidado como uma responsabilidade do seu papel na família / Most studies of the family\'s role in the continuity of treatment after the first epidode psychosis investigate cases of abandonment treatment and point to \"negative aspects of family\". Few studies have investigated the role of the family in cases of patients who remain in treatment. Objective: Understand the experience of caring of a familiar in PEP and highlight the motivations to remain in care. Method: This is a qualitative research that used the systemic family theory as the theoretical framework and the narrative as a methodological framework. 13 family caregivers of 12 patients were interviewed. To carry out the interviews with narrative approach was used the following question: We know that few families remain in mental health treatment of their sick young familiar after the first episode psychosis. Maintain the treating and taking care of the patient is called engagement. These are actions like take into consultations, administer medications, so as to relate, take care of hygiene and so on. Therefore, we would like you to tell us what motivates you to stay caring after everything you and your family are sickened by his family. For the exploration of the narratives was used the inductive content analysis technique. Results: The analysis of the narrative set the familiar engagement in three major interdependent categories. One is related to the context of feelings involved in the care called \"Motivations for engagement,\" the other two refer to actions related to care called \"The engagement actions\" and \"The assessment of care.\" Conclusion: The study contributes to the knowledge to present actively involved families in caring of the young in treatment of first episode psychosis. The theoretical - methodological possible highlight and enhance the stories, experiences and family relations involved in the care of a loved one. Care were described and contextualized in the cultural values of families. We found that family members perceive care as a responsibility of their role in the family

Orientador: Débora Isane Ratner Kirschbaum Nitkin / Tese (doutorado) - Universidade Estadual de Campinas, Faculdade de Enfermagem / Made available in DSpace on 2018-08-24T03:02:22Z (GMT). No. of bitstreams: 1 Kurimoto_TeresaCristinadaSilva_D.pdf: 10231955 bytes, checksum: d85d1b08e9a05717a23991b4ce59cea5 (MD5) Previous issue date: 2013 / Resumo: O cuidado de enfermagem na área da Saúde Mental no Brasil vem, nas últimas décadas, passando por transformações. A constituição de uma rede de serviços de saúde mental de base comunitária, organizada a partir de concepções próprias Ao Modo Psicossocial, favoreceu o nascimento e disseminação de práticas de enfermagem orientadas por princípios teóricos alinhados com a chamada clinica do sujeito. Algumas elaborações teóricas iniciais vem se ocupando dessas questões, mas lacunas permanecem no que diz respeito às práticas de cuidado voltadas a sujeitos psicóticos. Acredita-se assim, que a inclusão, no cuidado de enfermagem em psiquiatria/saúde mental, das concepções advindas da clínica do sujeito, pensada a partir da teoria psicanalítica, possa ter resultado em deslocamentos e ressignificações das concepções que tradicionalmente vem embasando esse cuidado, produzindo, assim, um saber e fazer (novos dispositivos). O objetivo desse estudo é identificar e analisar concepções de cuidado de enfermagem, articuladas sob a forma de princípios e dispositivos de cuidado, nas práticas exercidas por enfermeiros de saúde mental que as identificam como alinhadas à construção de uma clínica do sujeito. Trata-se de um estudo qualitativo, especificamente, uma pesquisa narrativa com interface etnográfica, tendo a teoria psicanalítica por referencial teórico. A ausência de estudos que sintetizassem as concepções de cuidado de enfermagem em saúde mental/psiquiatria a partir do início da Reforma Psiquiátrica Brasileira, ocorrida em 1980, impôs a necessidade de uma Revisão Qualitativa Sistemática da qual foram extraíram-se duas concepções de cuidado denominadas, nessa pesquisa, como: (1) 'Avesso do Cuidado' e (2) 'Inspirações Nightingaleanas', esta subdividida em: Relacionamento Interpessoal Terapêutico e Modo Psicossocial. Os sujeitos da pesquisa foram 19 enfermeiros brasileiros que produziram narrativas acerca de sua prática que explicitaram as concepções de cuidado de enfermagem que os norteia em seu trabalho. As concepções extraídas das narrativas dialogaram com o arcabouço teórico da psicanálise, a saber, a noção da Prática entre Vários e de suas consequências para o trabalho com psicóticos nas instituições a partir de Freud e Lacan. Dialogaram também com a discussão epistemológica acerca do saber de enfermagem proposta por Barbara Carper e revista por Patricia Munhall. Dessa análise resultou as seguintes discussões: (1) O 'Cuidado esvaziado'(N5): Discursos e saberes (saber e não-saber) que conformam o cuidado de enfermagem. Um cuidado é Esvaziado, quando se vale do esvaziamento da posição de saber prévio, ou seja, sem mestria. O Cuidado Esvaziado vale-se da posição de não-saber, assim como prescinde da ilusão de que, no tempo certo, poder-se-ia, com as perguntas certas ou mesmo com algum tipo de vínculo, vir a saber. (2) O cuidado de enfermagem na psicose: o anteparo da beleza ou o cuidado e suas coisas de fineza. No cotidiano do lidar com o corpo e seus odores, excreções, secreções, o cuidar revela um real junto ao qual a beleza pode funcionar como anteparo possível. Assim, um cuidado que se embasa num saber de sutilezas, de coisas de fineza, talvez possa, por convocar algo do registro imaginário e da ordem simbólica, limitar o real, que, na psicose, ganha estatuto de realidade, de concretude, de certeza. (3) "Não como todo mundo": o um que marca uma posição ética. Esse cuidado que se volta ao sujeito, ao seu modo único de lidar com seu sofrer, vale-se da responsabilização e a inclusão do sujeito como pontos nodais. Dessa forma, o enfermeiro pode conseguir fazê-lo, de uma posição ética, isentando-se de tomar o lugar de quem tem todas as soluções. (4) Um cuidar que afeta: acerca de palavras, atos e posições. Como sujeito, às voltas com seu inconsciente, é fundamental que o profissional inspire-se na posição de objeto do analista que implica não se apresentar como alguém que sabe o que é melhor para o outro e assim se propõe cuidar. Assim é o não-saber, enquanto posição discursiva, que, ao contrário de permitir ao profissional um ausentar-se, convoca-o em sua responsabilidade. A análise revelou que quanto aos dispositivos de cuidados, os narradores não se apresentaram novidades, mas referiram-se a ações de cuidado já estabelecidas que ganharam novas leituras e, nesse sentido, abriram novas perspectivas quando embasadas por conceitos advindos da teoria psicanalítica. O cuidado de enfermagem, na perspectiva da Prática entre Vários, encontra as condições para se constituir enquanto tal, embora do ponto de vista das práticas, continue incluindo um fazer sobre o corpo, seus odores e humores, sem, no entanto, prescindir das coisas de fineza. Coisas e questões essenciais ao cuidado de enfermagem que se norteia pela clínica do sujeito, não somente por introduzir novas concepções e perspectivas, mas por trazer a noção de que pode haver algum deslocamento, alguma dialética entre esse cuidado que se faz no corpo e esse cuidado que se norteia pela palavra / Abstract: Over the last decades nursing care in the field of Mental Health has been through several changes. A community mental health care network has been organized in the light of a so called Psychosocial Mode. It created favourable conditions for the birth and dissemination of nursing practices oriented by the clinic of the subject, an overarching approach strongly influenced by psychoanalytical perspectives. Some developments in that approach have been focusing issues pertinent to the articulation of nursing care from the Lacanian's clinic of the subject, but there are gaps regarding to the nuances of these practices addressed to psychotic subjects and how they are structured within this approach. The presupposition that supports this study is that the integration of the conceptualizations of the clinic of the subject grounded in psychoanalytical theory into the psychiatric or mental health nursing care may be fostered ressignifications of the traditional ways of conceptualizing such practice and displacements in the manner of practicing it. And, as a result, it may be produced the construction of a distinct knowledge and practices embodied in what has been called new dispositives. The purpose of the study is to identify and analyze the conceptualizations of nursing care, articulated as principles and dispositives of caring, which are embedded in the clinical practices developed by mental health nurses who align themselves with the construction of a clinic of the subject psychoanalytically oriented. This is a qualitative research in which the Narrative Research was combined with Etnography Research and has the Lacanian Psychoanalysis as theoretical framework. The lack of recent studies that synthesize the conceptualizations of nursing care and its nature within the psychiatric and mental health care areas since the beginning of the Brazilian Health Care Reform arose the need for a Systematic Qualitative Research. The results of this review showed that the conceptualizations of caring have been organized according two different categories here designated as (1) The other side caring and (2) 'Nightingalean Inspirations', which is subdivided in Therapeutic Interpersonal Relationship and Psychosocial Mode. The subjects of research were 19 Brazilian nurses, whose narratives detailed shows the conceptualizations of caring which guide their work. The narratives were analyzed in the light of the theoretical framework of Psychoanalysis, and specifically inspired in the notion of a Clinic Practiced among many therapists, and its implications for the work with psychotic patients in institutions departing from Freud's and Lacan's formulations. In the analyses of the narratives, a dialogue with the epistemological discussion inaugurated by Barbara Carper and reviewed by Patricia Munhall was also articulated. It produced the following arguments: (1) The 'Emptied care'(N5): Speeches and knowledge (knowing and not-knowing) that make nursing care. A care is Emptied, when comes from an empty position prior knowledge, i.e. without mastery. Emptied Care uses its position of not knowing, and rejects the illusion that, in time, it would be possible to come to know with the right questions or even with some kind of connection. (2) The nursing care in psychosis: the foresight of beauty or care and its finesse. The daily life of dealing with the body and its odors, excretions, secretions, caring reveals a reality from where beauty can work as a possible foresight. Therefore, a care that is grounded in the knowledge of the subtleties, of finesse things, might, by calling something from the imaginary memory and from the symbolic order, limit the reality which in psychosis earns, for sure, a statute of reality, of concreteness and of assurance. (3) "Not like everyone else": the one that marks an ethical position. A care that turns to the subject, its unique way of dealing with his suffering, relies on liability and the inclusion of the subject as nodal points. Thus, nurses can manage to do it from an ethical position, exempting themselves of taking the place of someone who has all the solutions. (4) A caring that affects: about words, acts and attitudes. As a subject, dealing with his unconscious, it is essential that the professional get inspire by a position of object that implies not presenting himself as someone longing, or someone who knows what is best for the other and thus offers to care. So it is the unknowing, as a discursive position, that calls for the professional responsibility rather than his absent. The analysis revealed what the narrators weren't presented novelties about dispositives of the care , but they referred to the actions of care established that won new readings and, accordingly, have opened new perspectives when backed up by deriving concepts Lacanian Psychoanalysis theory. The nursing care within the clinic practiced among many therapists finds the ideal conditions to constitute itself as such, at the same time that includes a practice concerning the body, its humours and odours, without prescinding from matters of finesse. These matters and their resulting issues are essential within a nursing care which is oriented by the clinic of the subject not only because it introduces new concepts and perspectives, but also for bringing forth the idea that in between the dialectic of care of the body and care that is directed through the words there may be some displacement, some a dialectic between this care what is done in body and that this care is guided by the word / Doutorado / Enfermagem e Trabalho / Doutora em Enfermagem