Yes / Aims: Theoretical arguments and empirical evidence have been provided in the literature for the role of fairness in wellness. In this paper we explore the role of two potential mediating variables: autonomous human choice and social capital. Methods: Using aggregated panel data across countries belonging to the Organisation for Economic Co-operation and Development (OECD) we compared the OECD Social Justice Index with data on life satisfaction to test whether fairness has direct and indirect effects on wellness. Results: Results from a series of Manifest Path Analyses with time as fixed effect, support the hypothesis that the OECD Social Justice Index is directly linked to country-level life satisfaction and also reveal that its indirect effect operates primarily through people’s autonomous choices in life and their country’s level of social capital. Conclusions: Our results contribute to two distinct bodies of knowledge. With respect to community psychology, the findings offer empirical evidence for the synergistic effect of personal, relational, and collective factors in well-being. With respect to the impact of economic inequality on wellness, we extend the literature by using social justice as a more comprehensive measure. Limitation and recommendations for future studies are discussed. / Research Development Fund Publication Prize Award winner, Jan 2022.

Yes / Random sets are used to get a continuous partition of the cardinality of the union of many overlapping sets. The formalism uses Möbius transforms and adapts Shapley's methodology in cooperative game theory, into the context of set theory. These ideas are subsequently generalized into the context of finite-dimensional Hilbert spaces. Using random projectors into the subspaces spanned by states from a total set, we construct an infinite number of continuous resolutions of the identity, that involve Hermitian positive semi-definite operators. The simplest one is the diagonal continuous resolution of the identity, and it is used to expand an arbitrary vector in terms of a continuum of components. It is also used to define the function on the 'probabilistic quadrant' , which is analogous to the Wigner function for the harmonic oscillator, on the phase-space plane. Systems with finite-dimensional Hilbert space (which are naturally described with discrete variables) are described here with continuous probabilistic variables. / Research Development Fund Publication Prize Award winner, October 2019.

Yes / Drawing from 645 microfinance institutions across 56 countries, this paper examines the deposit-borrowing dynamic of microfinance institutions’ source of capital. We find that deposits and borrowings are substitutes rather than complements. We further find that the degree of substitutability is more pronounced among microfinance institutions operating in a developed financial sector where the level of information asymmetry is lower. Our findings represent novel contribution in understanding microfinance institutions’ funding behaviour that supports its quest for further growth and long-term sustainability. / Research Development Fund Publication Prize Award winner, April 2023.

Yes / Carbon monoxide (CO) is both a substance hazardous to health and a side product of a number of industrial processes, such as methanol steam reforming and large-scale oxidation reactions. The separation of CO from nitrogen (N2) in industrial processes is considered to be difficult because of the similarities of their electronic structures, sizes, and physicochemical properties (e.g., boiling points). Carbon monoxide is also a major poison in fuel cells because of its adsorption onto the active sites of the catalysts. It is therefore of the utmost economic importance to discover new materials that enable effective CO capture and release under mild conditions. However, methods to specifically absorb and easily release CO in the presence of contaminants, such as water, nitrogen, carbon dioxide, and oxygen, at ambient temperature are not available. Here, we report the simple and versatile fabrication of a new class of hybrid materials that allows capture and release of carbon monoxide under mild conditions. We found that carborane-containing metal complexes encapsulated in networks made of poly(dimethylsiloxane) react with CO, even when immersed in water, leading to dramatic color and infrared signature changes. Furthermore, we found that the CO can be easily released from the materials by simply dipping the networks into an organic solvent for less than 1 min, at ambient temperature and pressure, which not only offers a straightforward recycling method, but also a new method for the “on-demand” release of carbon monoxide. We illustrated the utilization of the on-demand release of CO from the networks by carrying out a carbonylation reaction on an electron-deficient metal complex that led to the formation of the CO-adduct, with concomitant recycling of the gel. We anticipate that our sponge-like materials and scalable methodology will open up new avenues for the storage, transport, and controlled release of CO, the silent killer and a major industrial poison. / The Royal Society, The Romanian Ministry of Education and Research, The University of Bradford, European Regional Development Fund of the European Union / Research Development Fund Publication Prize Award winner.

Yes / Cocrystals consist of two molecules bonded together in a single crystal lattice giving rise to wide applications including improving solubility of poorly soluble pharmaceuticals. Cocrystallization reaction occurs in the oily phase of liquid–liquid phase separation (LLPS) after it is mixed with coformers. Indomethacin–saccharin cocrystal formation was monitored in situ, and the kinetics of crystallization were determined. The crystallization rates show that the process can be proposed to prevent unwanted oily phase formation during LLPS. / Research Development Fund Publication Prize Award winner, Sep 2022.

Yes / Beneficial effects have been observed following the transplant of lipoaspirates containing adipose-derived stem cells into chronic wounds caused by oncologic radiotherapy. It is not yet certain whether adipose-derived stem cells are resistant to radiation exposure. Therefore, the aims of this study were to isolate stromal vascular fraction from human breast tissue exposed to radiotherapy and determine the presence of adipose-derived stem cells. Stromal vascular fraction from irradiated donor tissue was compared to commercially sourced pre-adipocytes. Immunocytochemistry was used to determine the presence of adipose-derived stem cell markers. Conditioned media from stromal vascular fraction isolated from irradiated donors was used as a treatment in a scratch wound assay of dermal fibroblasts also isolated from irradiated donors and compared to pre-adipocyte conditioned media and serum free control. This is the first report of human stromal vascular fraction being cultured from previously irradiated breast tissue. Stromal vascular fraction conditioned media from irradiated donors had a similar effect in increasing the migration of dermal fibroblasts from irradiated skin to pre-adipocyte conditioned media from healthy donors. Therefore, the ability of adipose-derived stem cells in the stromal vascular fraction to stimulate dermal fibroblasts in wound healing appears to be preserved following radiotherapy. This study demonstrates that stromal vascular fraction from irradiated patients is viable, functional and may have potential for regenerative medicine techniques following radiotherapy. / This research was funded by a Bradford City FC Supporters Fellowship for L.V.T. administered through the Plastic Surgery and Burns Research Unit, University of Bradford. / Research Development Fund Publication Prize Award winner, Mar 2023.

Yes / Execution of lineage-specific differentiation programs requires tight coordination between many regulators including Ten-eleven translocation (TET) family enzymes, catalyzing 5-methylcytosine oxidation in DNA. Here, by using Keratin 14–Cre–driven ablation of Tet genes in skin epithelial cells, we demonstrate that ablation of Tet2/Tet3 results in marked alterations of hair shape and length followed by hair loss. We show that, through DNA demethylation, Tet2/Tet3 control chromatin accessibility and Dlx3 binding and promoter activity of the Krt25 and Krt28 genes regulating hair shape, as well as regulate interactions between the Krt28 gene promoter and distal enhancer. Moreover, Tet2/Tet3 also control three-dimensional chromatin topology in Keratin type I/II gene loci via DNA methylation–independent mechanisms. These data demonstrate the essential roles for Tet2/3 in establishment of lineage-specific gene expression program and control of Dlx3/Krt25/Krt28 axis in hair follicle epithelial cells and implicate modulation of DNA methylation as a novel approach for hair growth control. / This work was supported by the National Institutes of Health grant 5R01 AR075776 (V.A.B. and A.A.S.) and grant 5R01 AR071727 (V.A.B. and A.A.S.) and the National Science Foundation of China (G.-L.X.). / Research Development Fund Publication Prize Award winner, Dec 2022.

Магистерская диссертация посвящена исследованию феномена электронного книгоиздания с точки зрения исследования рынка. Проведен аналитический обзор темы, дана характеристика специфических особенностей электронных изданий и каналов их дистрибуции, проанализированы статистические данные по российскому книжному рынку за 2021–2022 гг. На основании проведенного анализа выявлены тенденции, проблемы и перспективы развития электронного книгоиздания в России. / Master's thesis is devoted to the study of the electronic book publishing phenomenon from the marketing point of view. An analytical review of the topic was carried out, characteristics of the specific features of electronic publications and their distribution channels were given, and statistical data on the Russian book market for 2021–2022 was analyzed. Based on the analysis, trends, problems and prospects for the development of electronic book publishing in Russia were identified.

京都大学 / 新制・課程博士 / 博士(工学) / 甲第25260号 / 工博第5219号 / 新制||工||1995(附属図書館) / 京都大学大学院工学研究科都市社会工学専攻 / (主査)教授 角 哲也, 教授 山上 路生, 教授 中谷 加奈 / 学位規則第4条第1項該当 / Doctor of Agricultural Science / Kyoto University / DGAM

京都大学 / 新制・課程博士 / 博士(地域研究) / 甲第25414号 / 地博第332号 / 新制||地||130(附属図書館) / 京都大学大学院アジア・アフリカ地域研究研究科アフリカ地域研究専攻 / (主査)准教授 金子 守恵, 教授 大山 修一, 准教授 原田 英典, 教授 高田 明 / 学位規則第4条第1項該当 / Doctor of Area Studies / Kyoto University / DGAM