"Literature" at the end of each chapter. / Special Collections copy submitted together with 5 selected reprints as the author's thesis (D.Sc.)-- University of Adelaide, 1935. / xi, 324 p. : / Title page, contents and abstract only. The complete thesis in print form is available from the University Library. / Thesis (D.Sc.)--University of Adelaide, 1935

"Literature" at the end of each chapter. / Special Collections copy submitted together with 5 selected reprints as the author's thesis (D.Sc.)-- University of Adelaide, 1935. / xi, 324 p. : / Title page, contents and abstract only. The complete thesis in print form is available from the University Library. / Thesis (D.Sc.)--University of Adelaide, 1935

The number of certified buildings in Miljöbyggnad has highly increased during the last decade and today it is the most common environmental certification system in Sweden. A new building gets a preliminary certificate in Miljöbyggnad at first that has to be verified within two years after the building is put in use. Today, only a few buildings have been verified. Therefore the ones who are involved in a project that is going to be verified have to work in a new way in compare to a standard project. This thesis examines Rudbeck Lab 4 in order to identify how to ensure that the preliminary certification rating is achieved at verification. Which indicators that are the most critical have been identified and also a risk analysis of Rudbeck Lab 4's rating in Miljöbyggnad has been done. The most important aspects to examine to ensure that the preliminary certification rating is accomplished when verified are; everybody who is involved in the project's knowledge of Miljöbyggnad, the residents understanding of Miljöbyggnad, structured environmental meetings and clear requirements. It is particularly important to have Miljöbyggnad in mind during the whole project and to create a plan for how the verification is going to be done. The most critical indicator that has been identified is Energy usage. Solar Load,Thermal climate winter, Thermal climate summer and Daylight are indicators that also may need a particularly control before verification. Rudbeck Lab 4's chance to reach Miljöbyggnad GOLD is good. If the indicator Energy usage manage to achieve GOLD, the whole project should achieve the rating of GOLD. / Det har skett en stor ökning av miljöcertifierade byggnader under det senaste decenniet. Miljöbyggnad är det vanligaste miljöcertifierings-systemet i Sverige med 736 certifierade byggnader i skrivande stund. I Miljöbyggnad får en nyproducerad byggnad först ett preliminärt betyg som måste verifieras tidigast ett år och senast två år efter att byggnaden tagits i bruk. Eftersom att enbart ett fåtal byggnader har blivit verifierade innebär det ett nytt arbetsutförande för många inblandade aktörer i och med att miljöcertifieringen måste inarbetas i den ordinarie byggprocessen. I det här examensarbetet undersöks Rudbeck Lab 4 genom studier av projektets handlingar och intervjuer med nyckelpersoner i projektet. Syftet är att identifiera hur det säkerställs på bästa sätt att det preliminära certifieringsbetyget uppnås vid verifiering. Vilka indikatorer som är de mest kritiska har identifieras och det har även utförts en riskanalys av Rudbeck Lab 4:s Miljöbyggnadsbetyg. De viktigaste aspekterna att utreda för att säkerställa att betyget från preliminärcertifieringen uppnås vid verifiering är; kunskap hos inblandade aktörer, brukarnas förståelse för miljöcertifieringen, uppförandet av strukturerade möten och tydliga kravställningar. Det är särskilt viktigt att arbeta in miljöcertifieringen i hela byggprocessen och att skapa en utförlig plan inför verifieringen. Den mest kritiska indikatorn som har identifierats är Energianvändning. Även Solvärmelast, Termiskt klimat vinter, Termiskt klimat sommar och Dagsljus är indikatorer som kan behöva särskilda kontroller inför verifieringen. Uppnår den mest kritiska indikatorn Energianvändning betyget GULD för Rudbeck Lab 4 finns det goda chanser att byggnadsbetyget blir GULD.

Submitted by Luciana Ferreira (lucgeral@gmail.com) on 2014-08-15T12:30:24Z No. of bitstreams: 2 license_rdf: 23148 bytes, checksum: 9da0b6dfac957114c6a7714714b86306 (MD5) dissertacao-lucas-1.pdf: 395719 bytes, checksum: 853c88b4092e0da7fb4784c37434ccbe (MD5) / Made available in DSpace on 2014-08-15T12:30:24Z (GMT). No. of bitstreams: 2 license_rdf: 23148 bytes, checksum: 9da0b6dfac957114c6a7714714b86306 (MD5) dissertacao-lucas-1.pdf: 395719 bytes, checksum: 853c88b4092e0da7fb4784c37434ccbe (MD5) Previous issue date: 2009-03-13 / language="eng">The present work has been based by the [16] and [17] articles, from Oscar J. Garay. In that articles he studied the conformally flat hypersurfaces in the R4 space, wich have the mean curvature vector H like an eigenvector of their Laplacian Operator, i.e., DH = lH, l 2R .We showed that these hypersurfaces are isoparametrics and, consequently, they are either a minimal hypersurface, or an around 3-sphere S3(r) , or a cylinder over a 2-sphere S2(r) R, or a cylinder over a circle S(r) R2. / Este trabalho foi baseado nos artigos [16] e [17] de Oscar J. Garay que consistem em estudar as hipersuperfícies conformemente planas em R4, cujo vetor curvatura média, H, ´e autovetor do operador Laplaciano, isto ´e, DH = lH, com l 2 R. Mostramos que estas hipersuperfícies são isoparamétricas e, consequentemente, são m´ınimas, ou uma hiperesfera S3(r), ou um cilindro cartesiano com uma 1-esfera R2 S1(r), ou um cilindro cartesiano com uma 2-esfera R S2(r).

Facial appearance has a strong effect on leadership selection. Ratings of perceived leadership ability from facial images have a pronounced influence on leadership selection in politics, from low-level municipal elections to the federal elections of the most powerful countries in the world. Furthermore, ratings of leadership ability from facial images of business leaders correlate with leadership performance as measured by profits earned. Two elements of facial appearance that have reliable effects of perceived leadership ability are perceived dominance and attractiveness. These cues have been predictive of leadership choices, both experimentally and in the real-world. Chapters 1 and 2 review research on face components that affect perceived dominance and attractiveness. Chapter 3 discusses how perceived dominance and attractiveness influence perception of leadership ability. Two characteristics that affect both perceived dominance and attractiveness are height and weight. Chapters 4-9 present empirical studies on two recently-discovered facial parameters: perceived height (how tall someone appears from their face) and facial adiposity (a reliable proxy of body mass index that influences perceived weight). Chapters 4 and 5 demonstrate that these facial parameters alter facial attractiveness. Chapters 6, 7, and 8 examine how perceived height and facial adiposity influence perceived leadership ability. Chapter 9 examines how perceived height alters leadership perception in war and peace contexts. Chapter 10 summarises the empirical research reported in the thesis and draws conclusions from the findings. Chapter 10 also lists proposals for future research that could further enhance our knowledge of how facial cues to perceived body size influence democratic leadership selection.

Transgenic manipulation of exogenous and endogenous gene expression in human embryonic stem cells (hESCs) is a powerful approach to decipher the genetic pathways dictating their developmental fate. Presently used genetic tools face limitations including leakiness in inducibility of expression, epigenetic silencing in long-term cell culture, low genomic integration efficiencies, small genetic cargo limit and lack of high-throughput cloning capabilities. To overcome these limitations, I have constructed R4-Integrase and piggyBac transposon genetic vector systems for stable transgene overexpression and knockdown in hESCs. Preliminary functional testing of the piggyBac vector system in HEK 293T and hESCs demonstrated vector inducibility as well as successful overexpression and knockdown of pluripotency factor OCT4. Concurrently, a cost-effective and high efficiency method for chemical transfection of hESCs was developed. Exogenous overexpression and knockdown of transcription factors in hESCs will aid in the elucidation of gene regulatory networks controlling pluripotency and developmental fate.

Transgenic manipulation of exogenous and endogenous gene expression in human embryonic stem cells (hESCs) is a powerful approach to decipher the genetic pathways dictating their developmental fate. Presently used genetic tools face limitations including leakiness in inducibility of expression, epigenetic silencing in long-term cell culture, low genomic integration efficiencies, small genetic cargo limit and lack of high-throughput cloning capabilities. To overcome these limitations, I have constructed R4-Integrase and piggyBac transposon genetic vector systems for stable transgene overexpression and knockdown in hESCs. Preliminary functional testing of the piggyBac vector system in HEK 293T and hESCs demonstrated vector inducibility as well as successful overexpression and knockdown of pluripotency factor OCT4. Concurrently, a cost-effective and high efficiency method for chemical transfection of hESCs was developed. Exogenous overexpression and knockdown of transcription factors in hESCs will aid in the elucidation of gene regulatory networks controlling pluripotency and developmental fate.

Nanoplasmonics has provided a way to control light with extremely high precision, into nanoscale volumes. In many circumstances, the nanoplasmonic devices which can be realised are fabricated using processing techniques which rely on planar technologies. This thesis provides a general method to make nanoplasmonic devices on a flexible membrane structure, which can be free standing, extremely thin (less than the wavelength of visible light), but retains the ability to be manipulated without loss of optical function. These devices are very pliant and conformable. Flexibility allows the integration of nanoplasmonic devices into many new applications where curved surfaces or the ability to conform to another object is required, as well as providing a route for post-fabrication tunability. Two specific applications are considered: lab-on-fibre technology and surface enhanced Raman spectroscopy. Lab-on-fibre technologies have been advancing the ability to miniaturise experiments which would normally require a whole laboratory. Fabricating a membrane and then later applying it to the fibre decouples the choice of fibre from the design of the device. Surface enhanced Raman spectroscopy is a powerful diagnostic tool which can uniquely identify an optical fingerprint of different molecules. The technique has been held back from widespread clinical adoption because of the difficulty of reproducibility of the substrates used. A repeatable and reliable rigid substrate is demonstrated, which can identify the concentration of a three component mixture of physiologically relevant biomolecules. This same design is then shown in a flexible form factor, which is applied to a non-planar landscape where it can identify the locations where a molecule of interest has been deposited. This thesis details the development of the fabrication protocol, the construction of experimental apparatus for characterisation, and the use of numerical modelling to advance the flexible nanoplasmonic membrane platform.

In the past decade, great research effort was inspired by the need to realise active optical functionalities in silicon, in order to develop the full potential of silicon as a photonic platform. In this thesis we explore the possibility of achieving tunable delay and optical gain in silicon, taking advantage of the unique dispersion capabilities of photonic crystals. To achieve tunable optical delay, we adopt a wavelength conversion and group velocity dispersion approach in a miniaturised engineered slow light photonic crystal waveguide. Our scheme is equivalent to a two-step indirect photonic transition, involving an alteration of both the frequency and momentum of an optical pulse, where the former is modified by the adiabatic tuning possibilities enabled by slow light. We apply this concept in a demonstration of continuous tunability of the delay of pulses, and exploit the ultrafast nature of the tuning process to demonstrate manipulation of a single pulse in a train of two pulses. In order to address the propagation loss intrinsic to slow light structures, with a prospect for improving the performance of the tunable delay device, we also investigate the nonlinear effect of stimulated Raman scattering as a means of introducing optical gain in silicon. We study the influence of slowdown factors and pump-induced losses on the evolution of a signal beam along the waveguide, as well as the role of linear propagation loss and mode profile changes typical of realistic photonic crystal structures. We then describe the work conducted for the experimental demonstration of such effect and its enhancement due to slow light. Finally, as the Raman nonlinearity may become useful also in photonic crystal nanocavities, which confine light in very small volumes, we discuss the design and realisation of structures which satisfy the basic requirements on the resonant modes needed for improving Raman scattering.

[pt] O principal objetivo deste trabalho é apresentar um novo método para visualização de variedades implícitas de dimensão 3 mergulhadas no R4. Esse método consiste primeiramente de um pré-processamento em CPU utilizando uma árvore 16-Tree e a Aritmética Intervalar para encontrar as regiões do domínio onde a variedade se encontra. Esses dados são posteriormente processados em GPU para efetuar a visualização, e para isso foi utilizada uma generalização da técnica Ray Casting. / [en] The main objective of this work is to present a new method for the visualization of implicit 3-manifolds in R4. This method consists primarily of a preprocessing in the CPU using a 16-tree and Interval Arithmetic to detect regions of the domain where the variety is present. These data are then processed in the GPU to perform the visualization, and for this a generalization of Ray Casting technique was adopted.