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  • About
  • The Global ETD Search service is a free service for researchers to find electronic theses and dissertations. This service is provided by the Networked Digital Library of Theses and Dissertations.
    Our metadata is collected from universities around the world. If you manage a university/consortium/country archive and want to be added, details can be found on the NDLTD website.
11

Harnessing retinal phagocytes to combat pathological neovascularization in ischemic retinopathies?

Klotzsche‑von Ameln, Anne, Sprott, David 02 February 2024 (has links)
Ischemic retinopathies (IR) are vision-threatening diseases that affect a substantial amount of people across all age groups worldwide. The current treatment options of photocoagulation and anti-VEGF therapy have side effects and are occasionally unable to prevent disease progression. It is therefore worthwhile to consider other molecular targets for the development of novel treatment strategies that could be safer and more efficient. During the manifestation of IR, the retina, normally an immune privileged tissue, encounters enhanced levels of cellular stress and inflammation that attract mononuclear phagocytes (MPs) from the blood stream and activate resident MPs (microglia). Activated MPs have a multitude of effects within the retinal tissue and have the potential to both counter and exacerbate the harmful tissue microenvironment. The present review discusses the current knowledge about the role of inflammation and activated retinal MPs in the major IRs: retinopathy of prematurity and diabetic retinopathy. We focus particularly on MPs and their secreted factors and cell–cell-based interactions between MPs and endothelial cells. We conclude that activated MPs play a major role in the manifestation and progression of IRs and could therefore become a promising new target for novel pharmacological intervention strategies in these diseases.
12

Investigation of prolactin-related vasoinhibin in sera from patients with diabetic retinopathy / Untersuchung von Prolactin-related Vasoinhibin in Sera von Patienten mit diabetischer Retinopathie

Triebel, Jakob 11 August 2010 (has links)
No description available.
13

Intraokularlinse Acri. Lyc 59 RET® mit unveränderter Brechkraft bei Silikonöltamponade / Acri. Lyc 59 RET ® IOL for unchanged refractive power with silicone oil tamponade

Baraki, Husnia 20 June 2011 (has links)
No description available.

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