京都大学 / 0048 / 新制・課程博士 / 博士(農学) / 甲第20440号 / 農博第2225号 / 新制||農||1049(附属図書館) / 学位論文||H29||N5061(農学部図書室) / 京都大学大学院農学研究科応用生命科学専攻 / (主査)教授 植田 充美, 教授 小川 順, 教授 渡邊 隆司 / 学位規則第4条第1項該当 / Doctor of Agricultural Science / Kyoto University / DFAM

The current energy crisis is exponentially growing and widening the chasm between demand and supply. Biofuels such as ethanol not only provide greener alternatives to fossil fuels but have been shown to reduce emissions from vehicles, improving air etc. Biofuel production from sources such as cellulose is believed to be more sustainable due to its low cost, vast availability in nature and sources such as industrial plant waste can be put to good use. However, due to the absence of a low-cost technology to overcome its recalcitrance, a concept called Consolidated Bioprocessing (CBP) has been put forward which proposes to integrate the production of saccharolytic enzymes, hydrolysis of the carbohydrate components to sugar molecules, and the fermentation of hexose and pentose sugars to biofuels into a single process. The present study involves development of cellulolytic E. coli strains towards cellodextrin assimilation by employing an energy-saving strategy in cellulose metabolism through the phosphorolytic cleavage of cellodextrin mixture produced as cellulosic degradation products.