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  • About
  • The Global ETD Search service is a free service for researchers to find electronic theses and dissertations. This service is provided by the Networked Digital Library of Theses and Dissertations.
    Our metadata is collected from universities around the world. If you manage a university/consortium/country archive and want to be added, details can be found on the NDLTD website.
1

A bacterial disease of the American shad (Alosa sapidissima)

Rothman, Stanley, microbiologist 23 January 1968 (has links)
For the past six years a bacterial infection has been the cause of large losses of adult, spawning, American shad (Alosa sapidissima) in the Coos, Millicoma and Smith Rivers of Oregon. There was a sizable commercial fishery for shad in these rivers and losses of fish due to this infection represented an important economic loss to the industry. This study was undertaken to determine the causative agent of the disease and describe the pathology of the disease. Fifteen strains of bacteria were isolated from diseased shad in the Coos, Millicoma, and Smith Rivers. Cultural and morphological studies, physiological reactions, animal infection, serological tests, and determination of the mole percent guanine + cytosine showed that the causative agent belonged in the genus Aeromonas. Since the shad disease isolates could cause "red leg" disease in frogs and "red mouth" disease in trout, they were named Aeromonas hydrophila. The disease was shown to be a bacterial hemorrhagic septicemia. Externally, the diseased shad had large hemorrhagic areas on their sides and reddening of the head and fins. Very little pathology could be seen internally. The causative organism was recovered from the spleen, liver, kidney, heart, blood and external lesions of the diseased animals. A review of the literature revealed that there was confusion in the nomenclature of the three motile species of bacteria included in the genus Aeromonas. Many authors felt that the three species (A. liquefaciens, A. hydrophila, A. punctata) were one distinct species. Comparative tests performed on the shad disease isolates and known cultures of Aeromonas failed to reveal major differences between these organisms. Attempts were made to separate the three species on the basis of the mole percent guanine + cytosine and thermal denaturation temperature (Tm) of the bacterial DNA. Three shad disease isolates had Tm values of 94.3, 94.6, and 94.2��C with corresponding mole percent guanine + cytosine values of 60.9, 61.7, and 60.7. An isolate of Aeromonas liquefaciens obtained from the Communicable Disease Center (CDC) in Atlanta, Georgia had a Tm of 94.1��C and a mole percent guanine + cytosine of 60.3. Aeromonas hydrophila (CDC) had a Tm of 95.4��C and a mole percent guanine + cytosine of 63.4 while A. punctata (CDC) had a Tm of 93.5��C and a mole percent guanine + cytosine value of 59.0. The mole percent guanine + cytosine results indicated that the shad disease bacterium was closely related to A. liquefaciens. The three known cultures of Aeromonas each had a distinct mole percent guanine + cytosine value. / Graduation date: 1968
2

An inaugural essay on the puerperal state of fever

Mitchell, George E. January 3705 (has links)
Thesis (M.D.)--University of Pennsylvania, 1805. / Microform version available in the Readex Early American Imprints series.
3

Introdução de um novo marcador laboratorial de atividade inflamatoria associada a infecção

Viner, Eliana Patron Chapira 14 July 1999 (has links)
Orientador: Morton Aaron Scheinberg / Dissertação (mestrado) - Universidade Estadual de Campinas, Instituto de Biologia / Made available in DSpace on 2018-07-25T06:00:57Z (GMT). No. of bitstreams: 1 Viner_ElianaPatronChapira_M.pdf: 1726639 bytes, checksum: 53821dfdf9223224697c0d187f6b37ca (MD5) Previous issue date: 1999 / Resumo: Evidencias clínicas e experimentais têm demonstrado que interleucinas proinflamatórias (TNFa, IL-1,IL-6,IL-8) são as mais importantes mediadoras na patogênese da Síndrome Séptica. Elas levam às flutuações de glóbulos brancos, elevações de proteínas de fase aguda como PCR e conseqüentemente a alteração na viscosidade das hemácias(VHS). Uma vez que estes marcadores apresentam comportamento variável em diversos estados clínicos de processos inflamatórios no homem, novos marcadores como a Procalcitonina (PCT) foram sendo descobertos. A PCT é um polipeptídeo de 116 aminoácidos e 13 kDa, é um precursor da calcitonina sem atividade hormonal. Em nosso estudo avaliamos os níveis de PCT, PCR, VHS e contagem do número de glóbulos brancos em 22 pacientes infectados, 12 portadores de infecção severa generalizada (Grupo I) e 10 portadores de patologias crônicas e infecções localizadas (Grupo 11). Os resultados destes pacientes foram comparados aos resultados obtidos em indivíduos sadios do grupo controle. A Procalcitonina mostrou-se útil em diferenciar os grupos estudados de forma significativa ao contrário dos outros elementos que se mostraram inespecíficos / Abstract: Clinical and experimental evidence have demonstrated that proinflammatory interleukines (TNF-a, IL-1,IL-6, IL-8) are the most important mediators in the pathogenesis of the Sepsis Syndrome. They lead to the fluctuation of the white blood cells, a rise in the acute phase proteins as CRP, and of consequence, the alteration in the viscosity of the blood leading to disturbance in the velocity of sedimentation (ESR). One of the new markers showing variation in several clinic conditions is Procalcitonin (PCT) The PCT is a polypeptide of 116 amino acids and 13kDa, it is a precursor of Calcitonin without hormonal activity. In our study we have evaluated the level of PCT, CRP, ESR, and enumerated the number of white blood cells in 22 infected patients, 12 with severe generalized infection (Sepsis)(Group I) and 10 with cronic pathologies and localized infections. The results obtained in healthy individuals of the control group were compared with the ill patients. The Procalcitonin (PCT) was shown to be useful to differentiate the groups studied in a statistic significant way, cO(1trary to the others markers of inflammation described so for that are non specific / Mestrado / Imunologia / Mestre em Ciências Biológicas
4

Community acquired bacteraemia : a prospective survey of 239 cases

Rayner, Brian L 06 April 2017 (has links)
The incidence and epidemiology of bacteraemia has been widely reported in the United States and Europe but little data is available from Southern Africa. In addition, most studies have concentrated on the overall incidence of bacteraemia, on individual organisms, or clinical situations, and it is difficult to interpret the data from these studies with regard to community acquired bacteraemia. From a retrospective survey of summaries from a single medical ward at Groote Schuur Hospital it was estimated that bacteraemia accounted for about 4% of the total admissions. It was therefore thought useful to provide clinicians particularly at Groote Schuur Hospital with information about community acquired bacteraemia to improve overall patient management. With this in mind it was decided to undertake a comprehensive prospective study of community acquired bacteraemia at Groote Schuur Hospital.
5

Infecções primárias de corrente sanguínea em UTI neonatal análise de três anos /

Rodrigues, Victor Hugo Bota January 2019 (has links)
Orientador: Maria Regina Bentlin / Resumo: INTRODUÇÃO: As infecções primárias de corrente sanguínea (IPCS) são responsáveis por aumento da morbimortalidade em recém-nascidos. OBJETIVOS: Determinar a incidência e a mortalidade das IPCS com confirmação laboratorial, após 72 horas de vida, em função dos agentes etiológicos, avaliar a resistência antimicrobiana dos agentes mais frequentes e rever o esquema de terapia empírica da Unidade. MÉTODOS: Estudo de coorte, retrospectivo, realizado na UTI Neonatal do Hospital das Clínicas - Faculdade de Medicina de Botucatu (UNESP), entre 2014 - 2016, após aprovação do Comitê de Ética. Critérios de inclusão: recém-nascidos com IPCS e hemocultura positiva após 72 horas de vida. Não incluídos agentes contaminantes e o crescimento de estafilococos coagulase negativa (SCoN) em apenas uma hemocultura. A amostra foi constituída por 71 recém-nascidos com 72 hemoculturas positivas. Foram estudadas variáveis maternas, gestacionais e do parto, procedimentos e resistência antimicrobiana. Desfechos: choque séptico e óbito. Os agentes foram comparados em grupos: Gram-positivos e Gram-negativos. Analise estatística: descritiva e comparação entre grupos com testes paramétricos e não paramétricos, com significância estatística de 5%. RESULTADOS: A incidência de IPCS foi de 10,2%, sendo 57% por Gram-positivos, 40% por Gram-negativos e 3% por fungos. A mortalidade foi de 21% e o óbito diretamente relacionado à IPCS ocorreu em 10% dos Gram-positivos e 14% dos Gram-negativos. Ventilação mecânica, uso ... (Resumo completo, clicar acesso eletrônico abaixo) / Mestre
6

Síndrome de respuesta inflamatoria sistemática (SRIS)/sepsis en el servicio de emergencia del Hospital Nacional Dos de Mayo

Navarro Moscoso, Hugo Mauricio January 2002 (has links)
OBJETIVO: Evidenciar la conducta clínica en el manejo de pacientes con SRIS/Sepsis. DISEÑO: Descriptivo-Observacional LUGAR Servicio de Emergencia del Hospital 2 de Mayo PACIENTES: 245 pacientes seleccionados entre el mes de Abril y Setiembre del 2000 que fueron admitidos a las diferentes salas de Emergencia (Observación, Trauma Shock, Neurocirugía, Traumatología e Intermedios-UCI), de los cuales 198 completaron criterios y 115 presentaron SRIS, de éstos ultimos 38 fueron SRIS no infeccioso y 77 Sepsis y estadios avanzados MEDIDAS Y RESULTADOS: Se evaluó la presencia de los criterios de SRIS, exámenes auxiliares, diagnósticos clínicos e intención de tratamiento. SRIS se encontró en 115 de los 198 estudiados, de los cuales 3 (8%) fueron efectivamente calificados como SRIS no infeccioso y 48 (62.3%) como Sepsis y estadios más avanzados, 37,3% de los pacientes sépticos principalmente en sepsis severa y falla multiorgánica no fueron definidos . Estos casos fueron definidos en forma temprana en 11/51 (21.6%) y tardía en 22/51 (43%). Los focos infecciosos identificados con mayor frecuencia fueron urinario (36,4%), pulmonar (20.1%) y piel y partes blandas (16.9%).El tratamiento fue catalogado como regular en 39.5% y eficaz en 21% fundamentalmente en UCI. El antibiótico de amplio espectro más usado fue Ceftriaxona (56.5%) CONCLUSIONES: No se utiliza la terminología de SRIS. La definición del estadio de Sepsis Severa y Shock séptico no siempre es registrada. El manejo clínico no es el óptimo.
7

Spring applied ammonium fertilizer with nitrification inhibitor and their effects on root and stalk rot of corn in Plainfield sand, Hancock, Wisconsin

Modjo, Hakam Sumadi, January 1978 (has links)
Thesis (M.S.)--Wisconsin. / Includes bibliographical references (leaves 79-82).
8

Experimental therapeutics for protection of liver failure from endotoxin-mediated sepsis

Wong, Kwong-fai. January 2008 (has links)
Thesis (Ph. D.)--University of Hong Kong, 2008. / Includes bibliographical references (leaf 102-116) Also available in print.
9

Experimental therapeutics for protection of liver failure from endotoxin-mediated sepsis /

Wong, Kwong-fai. January 2008 (has links)
Thesis (Ph. D.)--University of Hong Kong, 2008. / Includes bibliographical references (leaf 102-116) Also available online.
10

An inaugural essay, on the puerperal state of fever : submitted to the examination of the Rev. John Andrews ..., the Trustees and medical professors of the University of Pennsylvania, on the 5th day of June, 1805 : for the degree of Doctor of Medicine /

Mitchell, George E. Oswald, John H., M'Farlane, John Henry, January 3705 (has links)
Thesis (M.D.) -- University of Pennsylvania, 1805. / Film 633 reel 66 is part of Research Publications Early American Medical Imprints collection (RP reel 66, no. 1314). DNLM

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