The St. Lawrence Seaway and Power Project, built cooperatively between 1954 and 1959 by Canada and the United States, is the largest navigable inland waterway in the world and the largest borderlands project ever undertaken jointly by two countries. This thesis combines diplomatic, political, and environmental history to chart the course of domestic and international negotiations, particularly in the 1945-1954 period, that resulted in the bilateral 1954 agreement to build the seaway. The focus is on the Canadian federal government and to a lesser extent the U.S. federal government, as well as involved state and provincial governments and their public power utilities. These negotiations are extremely revealing in terms of the history of Canadian-American relations, and this thesis also examines issues connected to North American attitudes toward water resources, state-building, high modernism, and technology in the early Cold War period. After a number of failed attempts at a cooperative waterway, in the late 1940s the Liberal government of Louis St. Laurent began to explore the possibility of an all-Canadian seaway, and backed by widespread public support, had adopted this as policy by 1952. The drive for an all-Canadian seaway stemmed from various forms of nationalism which framed the St. Lawrence as an exclusively “Canadian” resource that was intimately tied to Canadian identity. However, the Truman administration and different American interests deemed a unilateral Canadian waterway to be an economic and national security threat to the United States, and delayed the requisite power licenses needed for Canada to undertake the transborder St. Lawrence project. Canada partly contributed to this situation by repeatedly making vague offers to leave the door open for American involvement in the hopes that this would expedite the hydro aspect of the project. The Eisenhower administration also stalled Ottawa’s efforts to “go it alone” until American participation was finally sanctioned by Congress in 1954 and the requisite licenses were granted. The St. Laurent government then reluctantly acquiesced to the American desire for a joint endeavour in order to maintain harmonious Canada-U.S. relations, although Canada did extract key concessions from Washington about the shape and placement of the project.

Since the 1960s, religious adherence in Canada has declined with ‘no religion’ slowly taking its place. Although British Columbia has been less religious than the rest of Canada since its early settler days, the currents of postwar secularization can still be assessed. In this thesis, I look at secularization on a denominational, regional, and gender specific scale. Through the oral testimonies of eleven women who were raised Catholic in Victoria, and who left Catholicism in the ‘long sixties,’ I discuss the way the Catholic Sisters of St Ann modeled autonomy for these women in how they were educated within the Catholic church and I investigate how cultural and societal discourse regarding women’s liberation, autonomy and individualism impacted their departure. In leaving the Catholic church, these women joined the ranks of the rising ‘religious nones’ in this region, however their departure from organized religion did not always mean a rejection of belief in a higher power or spirituality, with the majority retaining some form of spirituality throughout their lives. Despite this, their departure from institutional religion and lack of religious socialization for their children influenced the subsequent irreligiosity of their children and grandchildren. I argue that these women engaged with the calls for women’s autonomy in the long sixties, and in their actions influenced intergenerational secularization. / Graduate / 2022-09-10

L’activité plaquettaire joue un rôle clé dans la physiopathologie de l’infarctus du myocarde avec sus-décalage du segment ST (IDM ST+). La réactivité plaquettaire est augmentée lors d’un IDM ST+, traité par angioplastie primaire ou par fibrinolyse avec succès. La relation entre la réactivité plaquettaire résiduelle après un pré-traitement, la charge athérothrombotique et la qualité de la reperfusion myocardique reste peu décrite dans le cadre des IDM ST+. La tomographie par cohérence optique et celle plus récente par domaine de fréquence offrent une imagerie de haute résolution permettant l’identification et la quantification précise de la charge athérothrombotique intracoronaire (CAT). La CAT résiduelle intra-stent peut aider à mieux comprendre la relation entre la réactivité plaquettaire et la reperfusion. Dans un premier temps, nous avons évalué la précision des tests VerifyNow et PFA en comparaison à l’agrégométrie optique pour la détection de l’hyperréactivité plaquettaire dans le contexte particulier des IDM ST+ traités par fibrinolyse avec succès. Nous avons aussi décrit les caractéristiques de la CAT avant et après angioplastie selon la présence d’une rupture de plaque ou d’une érosion coronaire chez des patients traités par fibrinolyse avec succès. Ensuite, nous avons étudié la relation entre la réactivité plaquettaire résiduelle (en réponse au ticagrelor et à l’aspirine) mesurée par VerifyNow et la reperfusion myocardique chez des patients traités par angioplastie primaire. En parallèle, nous avons décrit la relation entre la reperfusion myocardique et la CAT résiduelle intra-stent dans la même cohorte. / Platelet activity plays a key role in the pathophysiology of ST-segment elevation myocardial infarction (STEMI). Platelet reactivity is enhanced after STEMI treated with primary percutaneous coronary intervention (PCI) or successful thrombolysis. The relationship between residual platelet reactivity after pre-treatment, the atherothrombotic burden and the quality of reperfusion remains poorly described in STEMI. Optical coherence tomography (OCT) and optical frequency domain imaging (OFDI) provide high resolution imaging allowing identification and accurate quantification of intracoronary atherothrombotic burden (ATB). Residual in-stent ATB may help to better understand the relation between platelet reactivity and reperfusion. First, we assessed the accuracy of the point-of-care tests VerifyNow and PFA in comparison to light transmittance aggregometry to detect high on-treatment platelet reactivity (HPR) in the particular setting of STEMI successfully treated with fibrinolysis. We also described the characteristics of ATB before and after PCI according to the underlying presence of rupture or erosion in patients successfully treated with fibrinolysis. Then, we assessed the relationship between residual platelet reactivity (in response to ticagrelor and aspirin) using VerifyNow and myocardial reperfusion in primary PCI patients. In parallel, we studied the relationship between myocardial reperfusion and residual in-stent ATB in the same cohort.

Background: This study aimed to evaluate the incremental prognostic value of infarct size, microvascular obstruction (MO), myocardial salvage index (MSI), and left ventricular ejection fraction (LV-EFCMR) assessed by cardiac magnetic resonance imaging (CMR) in comparison to traditional outcome markers in patients with ST-elevation myocardial infarction (STEMI) reperfused by primary percutaneous intervention (PCI). Methods: STEMI patients reperfused by primary PCI (n = 278) within 12 hours after symptom onset underwent CMR three days after the index event (interquartile range [IQR] two to four). Infarct size and MO were measured 15 minutes after gadolinium injection. T2-weighted and contrast-enhanced CMR were used to calculate MSI. In addition, traditional outcome markers such as ST-segment resolution, pre- and post-PCI Thrombolysis In Myocardial Infarction (TIMI)-flow, maximum level of creatine kinase-MB, TIMI-risk score, and left ventricular ejection fraction assessed by echocardiography were determined in all patients. Clinical follow-up was conducted after 19 months (IQR 10 to 27). The primary endpoint was defined as a composite of death, myocardial reinfarction, and congestive heart failure (MACE). Results: In multivariable Cox regression analysis, adjusting for all traditional outcome parameters significantly associated with the primary endpoint in univariable analysis, MSI was identified as an independent predictor for the occurrence of MACE (Hazard ratio 0.94, 95% CI 0.92 to 0.96, P <0.001). Further, C-statistics comparing a model including only traditional outcome markers to a model including CMR parameters on top of traditional outcome markers revealed an incremental prognostic value of CMR parameters (0.74 versus 0.94, P <0.001). Conclusions: CMR parameters such as infarct size, MO, MSI, and LV-EFCMR add incremental prognostic value above traditional outcome markers alone in acute reperfused STEMI.

Das "Rossijskij institut istorii iskusstv" (Russisches Institut für die Geschichte der Künste) in St. Petersburg ist neben dem Moskauer "Institut iskusstvoznanija" das zweite russische Forschungsinstitut im geisteswissenschaftlichen Bereich. Obwohl um einiges älter als die seit 1944 existierende Moskauer Einrichtwlg vergleichbaren Zuschnitts - es wurde 1912 vom Grafen Zubov in seinem Palais gegenüber der Isaaks-Kathedrale gegründet - ist das Petersburger Institut im Westen wenig beachtet worden. Die wechselvolle Geschichte dieser Forschungsinstitution, die als Wiege der Formalistenschule um Viktor Sklovskij in die Annalen der modernen Geisteswissenschaften eingegangen ist, bedürfte noch einer eingehenden Untersuchung, wie sie hier nicht geleistet werden kann.

In den letzten Jahren hat die russische Musikwissenschaft die internationalen Ursprünge der russischen Musikkultur erneut zum Gegenstand ihres Interesses gemacht. Das betrifft insbesondere St. Petersburg, die \"europäischste\" Stadt Rußlands, die seit ihrer Gründung 1703 ausländische Mentalitäten gleichsam in sich aufsog.

In this article I would like to attract attention to the personality of Ludwig Wilhelm Maurer. As a brilliant virtuoso violinist, known in Russia since 1817, conductor of the French theatre in St. Petersburg since 1835, inspector of all Emperor theatres since 1841 and conductor of the Philharmonic and Concert societies, Ludwig Maurer was an advocate of the classic inheritance.

The work deals with the orders of canons regular that operated or still operate in our country (Canons Regular of St. Augustine, Premonstratensians, Order of St. Anthony). Attention is paid not only to the origin and history of paticular orders in the world and in Bohemian Lands but also to their representatives, saints or regular houses as well as to the works of art we are obliged to mentioned orders for their origin.

Die Sammlung von Texten, die wir hier vorlegen, geht auf „Ansagen zur Zeit“ zurück, die in den Jahren 2001 bis 2019 von damaligen Mitarbeitern des Ägyptologischen Instituts der Universität Leipzig in den „Universitätsvespern am Paulineraltar” gehalten wurden.

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