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Införandet av robotprocessautomatisering inom ett försäkringsbolag : Konsten att genomföra RPA-införandeprocessen samt definiera framgångsfaktorer för hantering av risker under resans gång / Implementation of Robot Process Automation Within an Insurance Company : The Art of Implementing the RPA Process and Defining Success Factors for Managing Risks Along the JourneyVashina, Olesya January 2021 (has links)
Användningen av Robot Processautomatisering (RPA) hos företag blir allt vanligare och det är viktigt att lyckas med RPA-införandet för att maximera syftet med automatiseringen samt undvika störningar i verksamheten. Det uppkommer en del risker under RPA-införandet som behöver hanteras. Dessa risker resulterar samtidigt i kunskap och värdefullt information som bör uppmärksammas vid RPA-införandeprocessen. Dessutom är det viktigt att ta hänsyn till långsiktiga effekter som inträffar efter RPA-införandet och analysera vilka konsekvenserna av dessa blir. Försäkringssektorn är inget undantag och den påverkas mycket av digitaliseringen. Det finns stora möjligheter till utveckling för svenska försäkringsbolag och RPA kan hjälpa till att hantera administrativa processersom förekommer mycket inom försäkringsbolag. RPA kan ge extra stöd för att hjälpa försäkringsföretag attautomatisera hela arbetsflöden och effektivisera ett större antal av verksamhetsprocesserna. Syftet med denna kandidatuppsats i informatik som presenteras i kapitel 1 Inledning är att beskriva och analysera organisatoriska framgångsfaktorer för hantering av risker vid RPA-införandet, underliggande komponenter till införande samt effekter efter införandet som påverkar olika intressentgrupper. För att få djupareperspektiv på undersökningsområdet fokuserar studien på en process som heter ”Adressändring företag i affärssystemet ” . I kapitel 2 Teori och tidigare studier presenteras relevanta teoretiska studier och utifrån dessa bygger uppsatsförfattaren en analysmodell. Fallstudiemetod tillämpas i uppsatsen och data samlas in från fallföretaget med hjälp av semistrukturerade intervjuer med sex representanter som involveras i RPA- införandet av valda processen. I kapitel 4 Analys modifieras och anpassas analysmodellen till fallföretaget. Den modifierade analysmodellen presenteras i avsnitt 4.5 Modifiering av analysmodell. I kapitel 5 Slutsatser presenteras de viktigaste slutsatserna från studien vilka är följande: Vid val av process som ska robotiseras ska processens egenskaper kunna sammankopplas med tekniska förutsättningar. Att de intressentgrupper som påverkas av processen som ska robotiseras involveras i RPA-införandet. Att tydligt definiera rollerna för de personer som involveras i RPA-projektet. Betydelsen av en standardiserad utbildning hos intressentgrupper i Fas 1 av införandeprocessen. ”Change management”/Förändringshantering är den centrala framgångsfaktorn för hantering av risker vid RPA införandeprocessen. Vikten av att definiera samt mäta effekter vid RPA införandet.
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EXTENDED PROGRESSION-FREE SURVIVAL ON FIRST LINE TREATMENT WITH DOCETAXEL IN PATIENT WITH METASTATIC TRIPLE NEGATIVE BREAST CARCINOMASharma, Purva, Kim, James, Jaishankar, Devapiran, Singal, Sakshi 18 March 2021 (has links)
Docetaxel is a chemotherapeutic agent in the taxane group of drugs which is commonly used in the first line setting for metastatic hormone receptor negative breast cancer. We present a case of a 46 year old female who was diagnosed with de novo triple negative metastatic breast carcinoma, and has had an extended progression free survival (PFS) of almost 5 years on first line single agent treatment with Docetaxel.
46 year old female presented with a large left breast mass as well as axillary mass which revealed grade 3 invasive ductal carcinoma of breast on biopsy of both sites. Tumor was estrogen and progesterone receptor negative. Pathology showed discordance in HER2 testing between FISH and IHC, however on repeat testing, HER2 was confirmed to be negative. PET/CT scan for staging revealed large left sided pleural effusion and abnormal soft tissue in the lower anterior and posterior chest on the left concerning for pleural metastases. Patient underwent CT guided biopsy of left lower pleural space which was consistent with metastatic adenocarcinoma with breast primary.
She was started on first line single agent chemotherapy with Docetaxel 100mg/m2 every 3 weeks. Tumor markers were non-contributory to assess disease response. Repeat systemic imaging in 3 months showed excellent partial response with decrease in size of breast mass, conglomerate axillary lymph nodes as well as pleural based metastatic foci. Patient had grade 1 neuropathy secondary to Docetaxel which was tolerable. Patient also had significant fatigue with warranted dose reduction by 20% after 6 months. She also demonstrated other adverse effects of Docetaxel such as nail dystrophy and mild blepharitis which were also tolerable.
Patient showed good tolerance to chemotherapy, with intermittent treatment holidays. CT scans continued to demonstrate good response with stable size of breast and lung masses. After two years of stable disease and fair tolerance (after completing 34 cycles), chemo regimen was changed to every 4 weeks per patient’s wish. She was also started on Gabapentin for chemotherapy related neuropathy.
At the end of 4 years, patient had completed 55 cycles of agent Docetaxel, maintaining ECOG of 1, with grade 2 neuropathy controlled with gabapentin.
Patient is currently 56 months out from her initial diagnosis of metastatic triple negative breast cancer and follow-up scans continue to show stable disease. She has developed profound fatigue after several months of treatment. Patient has also faced challenges with fluid retention secondary to Docetaxel. Although her performance status remains fair, patient is contemplating changing frequency of chemotherapy to every 5 or every 6 weeks.
Triple negative breast cancer is an aggressive disease with limited options of treatment with chemotherapy agents and no role for endocrine therapy or HER2 targeted treatment options. Docetaxel has shown to have median survival ranging between 10.1 to 14.7 months depending on the dose. Our patient has so far shown extended PFS of 56 months, with single agent Docetaxel in first line setting which surpasses current national averages.
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The Double Knee Bend- Characteristics and Coaching PointsCedar, William E.S., Hornsby, W. Guy, Mizuguchi, Satoshi, Stone, Michael H. 01 September 2019 (has links)
Excerpt:The purpose of this article is to present and discuss the phases of the pull that precede the power position, as well as present some suggestions for how to coach these positions...
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The impact of additive manufacturing on sustainability of inbound transportationCarlek, Johan, de Jonge, Lennart January 2020 (has links)
Background: Emerging technologies enables manufacturing companies the opportunity to stay competitive and at the same time focus on increasing their sustainability impact. One such technology is additive manufacturing which has the potential to change the way manufacturing is performed and impact entire supply chains of manufacturing companies. Multiple studies have been done in the twenty-first century regarding additive manufacturing’s sustainability impact on logistics, although there is little research that focus on impact of additive manufacturing on transportation from a sustainable perspective. Purpose: The purpose of this study is to explore the impact additive manufacturing has on the sustainability of inbound transportation. Method: A qualitative research strategy was used to explore the field of study through a multiple case study method. Through two cases, raw material providers and manufacturers within the additive manufacturing industry, data was gathered using semi-structed interviews. Conclusion: Findings from this study shows that additive manufacturing may have a sustainable impact on inbound transportation from an environmental, societal, and economic perspective. Additive manufacturing is more environmentally sustainable than conventional manufacturing for the inbound transportation leg from the raw material supplier to the manufacturing company since the technology requires lower volume of raw material to be transported, it leads to a higher transport efficiency, less frequent transportation need, and requires no return transportation. In economic impact it leads to fuel savings, less frequent transportation with less material, and a reduced inventory holding. Access to remote areas together with easier and safer material handling is the societal impact from using additive manufacturing instead of conventional manufacturing.
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Why CSR is a win-win concept : An explanatory study of the impact of CSR (Corporate Social Responsibility) on the attractiveness towards an employerHolm, Pontus, Banfalvi, Max, Berlin, Alex January 2020 (has links)
Background: The concept of CSR has become a more discussed topic in relation to employer attractiveness in recent years. Recent research pointed in the direction of CSR to be a vital tool to be utilised in order for employers to enhance their employer attractiveness. By implementing CSR within an organisations agenda, will initially increase the number of job applicants. However, employer attractiveness in relation to CSR was still treated as a generic term, and not divided into specific values. Therefore, the authors divided the values within employer attractiveness (Interest, Social, Economic, Development and Application Value) and investigated which of the five values within employer attractiveness that were positively impacted by CSR. Purpose: The purpose of this paper was to explain how CSR impact employer attractiveness. Methodology: This thesis had a quantitative research method based on previous studies, hence, a deductive approach. The purpose was of an explanatory nature and the authors utilized a cross-sectional research design. The authors created an online survey that gathered 280 responses through the use of non-probability sampling in the form of a convenience sample. Findings: In this study, four out of the five hypotheses were accepted meaning that CSR positively impacts employer attractiveness. Furthermore, the authors cross-checked the independent and dependent variables together with control questions such as gender, age and occupation. Resulting in gender, age and occupation not having a significant impact on the result. Conclusion: The authors conclude that CSR positively impacts employer attractiveness through the measured values of Interest, Social, Development and Application Value. The authors could not conclude that CSR had a positive impact on Economic Value meaning that the hypothesis (H3) was rejected.
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Design of secondary air system and thermal models for triple spool jet enginesCaty, Fabien January 2012 (has links)
This master thesis deals with the understanding of the secondary air system of athree spool turbofan. The main purpose is the creation of secondary air systemand thermal models to evaluate the behavior of this kind of engine architectureand estimate the pros and cons in comparison with a typical two spool turbofan. Afinite element model of the secondary air system of the engine has been designedbased on the experience of typical jet engines manufactured by Snecma. Theinner thermodynamic pattern and mass flow rates of the engine were obtained.Some local improvements were then made by making analogies with the enginesmanufactured by Snecma. After having communicated the results to theperformance unit to get updates thermodynamic cycles, a quite reliable model wasobtained and can be used as a reference for further studies of this kind of engineat Snecma.
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Controlled deposition and alignment of electrospun PMMA-g-PDMS nanofibers by novel electrospinning setups / Kontrollerad beläggning och linjering av elektrospunna PMMA-g-PDMS nanofibrer genom en ny elektrospinningsmetodHaseeb, Bashar January 2011 (has links)
Electrospinning is a useful technique that can generate micro- and nano-meter sized fibers from polymer materials. Modification of the electrospinning parameters and apparatus can generate nanofibers for use in diverse applications ranging from tissue engineering to nanocomposite fabrication; however, electrospun fibers are typically collected in a random orientation and over large areas limiting their applications. Here we present several methods to control the deposition of electrospun nanofibers, such as the use of a single auxiliary electrode ring and a negatively charged collector substrate to control the deposition area and the construction of a parallel electrode collector known as the triple electrode setup to control the uniaxial alignment of nanofibers. The numerous constructed setups were advanced by the use of electric field computations to assess the distribution of the electric field and its effect on the deposition behavior and morphology of the electrospun nanofibers. The electrostatic force imposed by the auxiliary electrodes provides converged electric fields that direct the nanofibers to their desired deposition targets. Here it is shown that the use of the auxiliary electrode ring dramatically decreased the deposition area of nanofibers, the negatively charged substrate yielded more uniform nanofibers and the triple electrode setup is a viable method to achieve uniaxially aligned nanofiber mats. The electrospinning of copolymers appears as an attractive option for enhancing the overall properties of nanofibers as it offers possibility of an intrinsic control of the polymeric material itself. The poly(methyl methacrylate)-graft-poly(dimethylsiloxane) graft copolymer (PMMA-g-PDMS) is considered to be an organic-inorganic hybrid material with much potential in its use in nanocomposites, and in this work has been successfully synthesized and electrospun via the various constructed electrospinning setups. In the final elements of this work, the triple electrode setup is used in combination with a dynamic rotating collector to yield a novel collector and has been successfully used to produce PMMA-g-PDMS nanofiber sheets that were further incorporated in a PDMS matrix to yield nanocomposite sheets. A variant of the triple electrode setup with partially insulated electrodes is devised in combination with a methodology to remove the nanofibers from the collector. The nanofibers once removed and dried were incorporated in a PDMS matrix to yield nanocomposites. The preferential dissolution of the fibers from the matrix rendered the fibers to templates and a final porous material with uniaxial nanochannels could be obtained. This work is believed to be able to lead to a better understanding of the mechanisms of nanofiber deposition and alignment, and should be of help to the design of more practical collecting structures, hence promoting the applications of the electrospinning technique.
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Who will save the world if the profit is too low? : A single case study on a Swedish business school, investigating their work toward responsible management educationJohansson Cimen, Jesper, Lithagen, Lisa January 2022 (has links)
Background: Business schools are one of society’s most influential institutions as they contribute to transforming and influencing the way the business world works. Hence, business schools bear responsibility for the creation of future, socially aware, graduates. Accordingly, the business industry expects business schools to educate future managers enhancing sustainability and ethical standards. Although it is argued that graduates in business schools get taught many professional skills and abilities to gain economic success, ethical and sustainable practices are often neglected. The schools are getting criticism for providing education distant and irrelevant to industry demands. Purpose: This study aims to create a deeper understanding of the phenomenon of responsible management education (RME) in business schools. The research can hopefully provide valuable insights, both practically and academically, for both the investigated school and other business schools while also providing a richer and more holistic view of the subject. Method: This single-case study uses an exploratory and abductive research approach. Empirical data have been collected through semi-structured interviews with participants from Jönköping International Business School. Data has also been collected through document analysis. To understand and analyze the findings, thematic analysis has been used. Findings: The findings show that RME has been implemented in various ways, both because the school itself believes it is highly important, but also because of the pressures stemming from various stakeholders and other institutional forces. Progress is found to have been made, yet the effects of that progress were not acknowledged significantly by either students or document analysis which might be due to a lack of a common definition of both RME and sustainability amongst staff and faculty. For the school to remain attractive, it is found important to continue its work towards RME and put equal emphasis on teaching financial, social, and environmental responsibilities.
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Sustainable corporate responses to stakeholders' pressures in French food companiesPasselande, Audrey, Sportes, Clara January 2022 (has links)
This research leads to investigate the response of French companies through their corporate sustainability policies as a result of the different types of pressure that stakeholders can bring. The influence of stakeholders is increasingly significant towards ethical and environmental issues. Stakeholders do not hesitate to set up actions to make themselves heard. Social and environmental concerns facing this polluting industry make food companies exposed to more and more pressures that they must manage. The academic literature necessary for the understanding of this study was carefully selected from online academic libraries. The literature review defined the objective of balancing Profit, People and Planet in corporate sustainability policies and its implementation through the Triple Bottom Line model. Also, the pressure groups are defined according to the academic literature and associated with Freeman's theory on stakeholders. This literature was coupled with collected primary data. Interviews were conducted with three French companies of different sizes to guarantee a realistic representation of the market. The interest of the inductive method used is to be able to apply the observations made on a larger scale. The results obtained are grouped under five themes to facilitate their identification: Quality, Ethics, Environment, Consumer's power, and Well-Being. Under each of these themes, one or more stakeholders exert pressures to achieve the same objective. The strategies adopted by companies vary according to the type of pressure they face. Each company adapts its corporate sustainability policies to the pressures according to its size. Large companies will be better resourced than small ones. All corporate actions have two objectives: the satisfaction of their stakeholders and the improvement of the company in terms of sustainability. This thesis contributes to the Stakeholder's theory and Triple Bottom Line model. The combination of these two theories is essential to explain the two converging phenomena of this thesis: pressures and sustainable responses.
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Sustainability Assessment of Ores and MetalsFrisk, Johan, Svantesson, Jonas January 2016 (has links)
The procurement of ores and metals necessitates consideration of the sustainability of both the productand of the producer. Current trends in procurement practices move toward assuring the lowestenvironmental, social and economic impacts feasible. In order to ensure a high level of sustainability inthe raw materials acquired, the practices and methods of the producers must be evaluated. To this enddifferent assessment models may be used. This report aims to, through an investigation ofcontemporary assessment models; develop an assessment model which facilitates the sustainableprocurement of ores and metals with a reduced need for compliance from the assessed parties. Theevaluation is carried out based on the triple bottom line (TBL) definition of sustainability and considersthe practices and needs of the ores and metals industry. A number of desirable traits were found in themodels evaluated. A design for a novel assessment model is proposed for scoring ore and metalproducers. The proposed model features recommendations for weighing methods and specifications forimpact indicators, measurement methods, and grading methods. / Malm- och metallindustri arbetar allt mer med hållbar utveckling. Detta kräver metoder för attsäkerställa att potentiella underleverantörer använder sig av procedurer och strategier som anses sundaur ett hållbarhetsperspektiv. För att undersöka detta finns etablerade bedömningsmodeller. Syftet meddenna rapport är att utvärdera dessa modeller för få en grund på vilken en ny modell, anpassad förmalm- och metallindustrin, kan utformas. Denna nya modell utformas för att minska krav av storaeftergifter från de aktörer som undersöks. Utvärderingen baseras på ”triple bottom line” -definitionenav hållbar utveckling och tar hänsyn till behoven som finns i industrin, och de metoder som redananvänds. Arbetet resulterade i att ett antal egenskaper som är önskvärda för en bedömningsmodellidentifierades. Med dessa egenskaper i beaktande utformades en ny bedömningsmodell medrekommendationer för viktning av betyg och specifikationer för mätpunkter, mätmetoder, ochbetygsmodeller.
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