Spinal motoneurons (MNs) relay neural commands from the brain to the muscles to produce functional movement. However, MNs are more than passive conduits of neural commands; they also shape motor output through alterations in their intrinsic excitability. These alterations allow MNs to modify (e.g., amplify and/or prolong) motor output even in the absence of descending motor commands. How MNs respond to this modulation, under various conditions, is not fully understood. In the scope of this dissertation, we leverage high-density electromyography and motor unit decomposition algorithms to investigate how human MNs behave in (Aim 1) different muscles under similar task demands; (Aim 2) the same muscle under different task demands; and (Aim 3) in response to exogenous neuromodulation. First, in Aim 1 we demonstrate that MN excitability varies across motor pools and, thus, may be functionally tuned to the task and its muscle-specific demands. The results indicate that the MN discharge rates were significantly higher in the first dorsal interosseous, a small hand muscle used for fine motor control. Conversely, higher MN excitability was observed within the tibialis anterior, a lower leg muscle involved in balance and locomotion. Next, in Aim 2 we show that a muscle (i.e., the biceps brachii) with multiple biomechanical functions (e.g., supination and flexion) receives differential synaptic input to perform each action while the MN discharge characteristics remain the same. Finally, in Aim 3 we demonstrate that a single cup of coffee can alter fundamental motor control mechanisms by increasing discharge rate, inter-pulse variability, and excitability through caffeine-induced neuromodulation. Collectively, findings from this dissertation demonstrate the human motor system’s tremendous ability to adapt to internal and external states. / Public Health

No / The purpose of this paper is to present a critical viewpoint on the negative aspects of market, price and cost transparencies to consumers in terms of its costs. It adopts an inter-disciplinary approach from the marketing, economics and accounting literature. The paper explores market transparency in the ever-changing world and uses brand names like Starbucks and iPhone to illuminate instances where imperfect markets are supported by consumers. Recognizing the role that the Internet plays in promoting price transparency, it espouses how extant information can add costs and risks to the consumer’s value judgement. Finally, the paper advocates that arbitrary judgements existing in cost accounting make it difficult to compare unit cost. This could result in consumers paying extra money to benefit from cost transparency. This paper argues that three main issues may arise in providing unit cost to the consumers. First, transparency entails built-in costs, whether they are in taxes or product prices. Second, in accounting, unit cost information is currently not equitable between businesses. Finally, the paper argues that extra time and effort in making sense of unit cost information lead to questions about the viability of transparent costing. The arguments for transparency have been widely discussed, supported and promoted by many. While negative aspects are known to businesses, few consider the consumer’s perspective. By amalgamating evidence and arguments from different disciplines, this paper lends value, providing a critical perspective where transparent unit cost revelation can be more costly and less viable than what is assumed.

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The unit load is the form of most commercial and industrial products during storage and distribution. A simple form of a unit load, a palletized bulk bin is commonly used to transport fruit and vegetables from the point of harvest to processing facilities. These vibration sensitive products are often subjected to damaging vibrations during this period. Most damage occurs during the large accelerations associated with resonance, which occurs when the natural frequency of the unit load matches the input frequencies commonly encountered during transportation. A computer model, called RoPUL (resonance of palletized unit loads), of a palletized bulk bin loaded with fruit, was developed using finite element analysis techniques. Unit loads consisting of palletized bulk bins of apples and peaches were tested and RoPUL was found to accurately predict the resonant frequencies of these loads. Using RoPUL, the effects of product mass, container design, and pallet design on natural frequencies can be analyzed. As the input frequencies of most transportation modes is well documented, RoPUL can be used to help design a unit load to better protects vibration sensitive products during shipment. / Ph. D.

Corrugated paper boxes are the predominant packaging and shipping material and account for the majority of packaging refuse by weight. Wooden pallets are equally predominant in shipping, transportation and warehousing logistics. The interaction between these two components is complex and unexplored leaving industry to compensate with outdated component specific safety factors. Providing a focused exploration of the box and pallet interaction will open the door for holistic design practices that will reduce cost, weight, damage, and safety incidents. This study was separated into four chapters exploring different aspects of the corrugated box to pallet interaction. The first chapter evaluates the support surface provided by a pallet consists of deckboards spaced perpendicular to the length of the pallet. The resulting gaps between deckboards reduce the support to the box. Gaps were limited to 55% of box sidewall length for practical reasons. The effect of gaps was significant and produced a nonlinear reduction in box strength. Small boxes were more susceptible to gaps than larger boxes. Moving the gap closer to the corner increased its effect while increasing the number of gaps did not increase the effect. A modification to the McKee equation was produced that was capable of predicting the loss in strength due to gaps. The equation is novel in that is modifies a widely used equation and is the first such equation capable of handling multiple box sizes. This study also has practical implications for packaging designers who must contend with pallet gap. Chapter 2 explores the relationship between deckboard deflection and box compression strength. Testing found that reducing the stiffness of the deckboard decreases the compression strength of the box by 26.4%. The location of the box relative to the stringer also had varying effects on the box strength. A combination of deckboard stiffness and gaps produced mixed with results with gaps reducing the effect of stiffness. It was observed that lower stiffness deckboards not only deflect but also twist during compression. The torsion is suspected to have a significant influence on compression but further exploration is needed. The third chapter tests the effect of box flap length on box compression strength under various support conditions. Variables included four flap lengths, gaps between deckboards, low stiffness deckboards, column stacking and misaligned stacking. The results show that the box flaps can be reduced by 25% with no significant effect of box strength under any support condition tested. Furthermore, the box flap can be reduced by 50% with less than 10% loss in compression strength under all scenarios. These results have significant sustainability implication as 25% and 50% reduction in box flap reduce material usage by approximately 12% and 24%, respectively. In the fourth and final chapter, the theory of beam-on-elastic foundation is applied to deckboard bending and corrugated boxes. In this model the corrugated box acts and the foundation and the deckboard is the beam. Rotational stiffness, load bridging, and foundation stiffness changes required the development of novel testing solution and model development. The model was capable of predicting the distribution of force along the length sidewall but was not capable of predicting the ultimate strength of the box. The model developed in the study will be applicable in determining potential weakness in the unit load in addition to optimizing those that are over designed. These four chapters represent a considerable contribution of applicable research to a field that relied on outdated safety factors over thirty years. These safety factors often lead to costly over design in an industry where corrugated box and pallets volumes make event the smallest improvements highly beneficial. Furthermore, this research has opened the door for significant additional research that will undoubtedly provided even greater economic and sustainability benefits. / Ph. D.

Excessive use of fossil fuels to meet everyday energy demands has led to adverse environmental impacts like global warming and high dependence on foreign oil. Development of cellulosic feedstocks provides energy security and also reduces the burden on food crops like corn and sugarcane used for ethanol production. This thesis uses cost-benefit analysis to ascertain the profitability of producing cellulosic ethanol from Switchgrass and Sweet Sorghum Bagasse. First, breakeven price of producing Switchgrass and Sweet Sorghum is calculated to obtain a raw material (feedstock) cost for ethanol production. Next, net present value (NPV) and minimum ethanol selling price (MESP) for Switchgrass and Sweet sorghum are calculated. Lastly, risk analysis is performed and its impacts on NPV are calculated for two farmer categories. The results show that ethanol production from Switchgrass and Sweet Sorghum is commercially feasible and generates a Net Present Value (NPV) of $39.54 million for Switchgrass and $96.76 million for Sweet Sorghum at an ethanol selling price of $2.17 per gallon. At NPV zero the MESP for Switchgrass and Sweet Sorghum is estimated to be $2.10 and $1.96 per gallon respectively. The risk analysis results revealed that there is a 9.5 percent probability that the NPV for a risk-averse Switchgrass farmer will be less than zero. On the other hand, the probability of the NPV being less than zero is 67.4 percent. The overall analysis indicates that ethanol production from Switchgrass and Sweet Sorghum is a promising option. Reduction in feedstock prices, optimization of the conversion process and additional revenues from by-products can make cellulosic ethanol more competitive with current gasoline prices. / Master of Science

Synchrophasor Measurement Units (PMUs) are devices that can not only measure but also time stamp voltage, current, frequency, among others. PMUs take these synchronized measurements as fast as 60 times per second; compared with the traditional 2-4 second SCADA measurements, PMUs bring a much clear and real-time picture of what is happening in the power system. PMUs have been increasingly deployed across transmission power grids worldwide. In the USA this is primarily done by utilities through projects sponsored mainly by SIGS and Smart Grid grants. There are different applications that synchrophasors can provide, including off-line and real-time applications. However, due to budget constraints, technology development and characteristics specific to each system, not all applications are equally suitable and essential for all electric power systems. This thesis provides a method for PMU applications prioritization based on the analysis and results of wide area disturbance events. / Master of Science

The Egyptian Fractions of One problem (EFO), asks the following question: Given a positive integer n, how many ways can 1 be expressed as the sum of n non-increasing unit fractions? In this paper, we verify a result concerning the EFO problem for n=8, and show the computational complexity of the problem can be severely lessened by new theorems concerning the structure of solutions to the EFO problem. / Master of Science / Expressing numbers as fractions has been the subject of one’s education since antiquity. This paper shows how we can write the number 1 as the sum of uniquely behaved fractions called “unit fractions”, that is, fractions with 1 in the numerator and some natural counting number in the denominator. Counting the number of ways this can be done reveals certain properties about the prime numbers, and how they interact with each other, as well as pushes the boundaries of computing power.