The first chapter outlines the history of the Korean peninsula from the period of the first kingdoms until the end of Korean War. Second chapter describes the present situation of the DPRK - its political system, ideology and economy and how it was influenced by its history. Third chapter is devoted to the foreign relations of North Korea with a focus on countries that play a special role. Last chapter focuses on the key factors that could influence the future development of the DPRK.

First chapter contains geographical and political characteristics of Peru and its history. Second part of the thesis includes economic characteristics of Peru and structure of foreign trade. Next chapter focuses on future development of Peru. Last chapter contains key characteristics of role of Peru within the latinamerican region.

The thesis provides an analysis of Swedish economic development since the accession to the EU till present with emphasis on a period of boom and crisis at the beginning of the 3rd millennium. Basic macroeconomic indicators, such as GDP growth, inflation rate, public balance, general government debt, unemployment rate, foreign direct investment, current account of balance of payments are used to describe the economic development of Sweden. The first chapter focuses on the Swedish economy from the accession to the EU till the turn of the millennium. The second chapter deals with the Swedish economic development during the years 2000-2006. The third chapter describes the economic development of Sweden during the global economic crisis in 2007-2009 including selected issues related to the crisis.

The thesis is concerned with a comparison of two rapid web development frameworks for the Java platform - Tapestry 5 and Grails. The goal is to get acquainted with both of the frameworks, explain their basic principles and usage, compare their solution to common challenges and their contribution to faster development. Furthermore, the goal is to de fine a set of criteria for the comparison and match each one of them with their respective weights representing their importance in certain decision making scenarios. The frameworks are new and under dynamic development, therefore the bene ts of this thesis are an extensive research in foreign resources, summary of the acquired knowledge, practical usage examples and furthermore the assessment of the frameworks' strenghts and weaknesses. The conclusions and comparison quanti cation can then be used to strategically choose the appropriate framework if necessarry.

The content of this diploma thesis is an analysis and a comparative study of the story of Tristan and Isolde. It depicts its literary development from the poetic form to the prose, starting from the Medieval Age to the present day. It delineates mainly the Medieval versions of the story in general, introduced the authors and summarizes the plots of the stories. Also, the modern versions of the story are briefly introduced.

Charles University Faculty of Pharmacy in Hradec Králové Department of Biophysics and Physical Chemistry Candidate: Monika Dohnalová Supervisor: Ing. Vladimír Kubíček, CSc. Title of Diploma Thesis: HPLC analysis of drugs The diploma thesis deals with the development and optimization of HPLC method for simultaneous determination of selected polyphenolic compounds: apigenin, acteoside and luteolin. During the experiments, the most suitable conditions for separation were sought, various mobile phases and various types of gradient elution were tested. The Zorbax Eclipse XBD C18 column 250 x 4.6 mm; 5 µm was used for analysis. The detection was performed with diode array detector at wavelengths 249 nm and 350 nm,the column was thermostated at 30 řC. The injected volume was 10 µl. The best results were achieved using mobile phase consisting of acetonitrile and aqueous solution of formic acid (0.03 mol/l) at a flow rate 1ml/min.

EVOLUTIONARY AND DEVELOPMENTAL ASPECTS OF DENTITION OF SQUAMATE REPTILES Summary of the PhD. thesis Dentition and its evolutionary modifications played important roles during the radiation of reptiles. It is generally accepted that a plesiomorphic state for reptiles is represented by homodont, polyphyodont dentition with conical or cylindroconical teeth. However, in contrast to mammalian dentition which is the object of intensive research, reptilian dentition is studied only rarely. I therefore focused on developmental and evolutionary aspects of squamate dentition and used histological, immunohistochemical and in situ hybridization methods, computerised tomography, rentgenography and scanning electron microskopy. The goals of this work were as following: (a) to choose the model taxa representing squamate lineages relevant from a phylogenetic position as well as possessing dissimilar types of dental adaptations; (b) to evaluate using of these taxa as model species; (c) in these taxa describe basic odontogenic features. As a species with generalized dentition gecko Paroedura picta was chosen, the up coming reptilian model species with features also present in a wide spectrum of other lizards. I focused mainly on the developmental differences between teeth of the null and functional generations, development...

6 III ABSTRACT (ENGLISH) In chordates, the central nervous system (CNS) is derived from the dorsal part of gastrula. Induced dorsal part of the embryo - the neural plate - gives rise to the neural tube or primordial brain. The developing dorsal part of the embryo is shaped by BMP/Smad signaling from the ventral part. Using the basal chordate amphioxus, we show here the conserved evolutionary role BMP/Smad signaling in axial cell fate determination. Pharmalogical inhibition of BMP/Smad signaling induces dorsalization of Branchiostoma floridae (amphioxus) and Oryzias latipes (medaka) embryos and expansion of neural plate markers. We provide evidence for the presence of the positive regulatory loop within the BMP/Smad signaling network of amphioxus. Thus, our data suggest that early emergence of a positive feedback loop within the BMP/Smad signaling network may represent a crucial molecular event in the evolutionary history of the chordate cell fate determination. The dorso-ventral body axis formation is mediated by genes of the vent family, which are the direct targets of BMP/Smad signaling. The function of vent gene family in early development is relatively well known, however, its role in developing CNS is not yet clear. Therefore, we decided to manipulate vox transcription factor, a vent family member....

In my work I focused on the preventive group program Estimulación temprana, which is intended for children from 0 to 3 years old and their parents. Six case studies are presented to help analyze this program. Research has revealed that the program is working on children through coarse and fine motor, cognitive, speech and social development. The case reports indicate that the observed individuals did not deteriorate, on the contrary, there was a shift in the Brunet-Lezin scale. Activities take into account the developmental level of groups in which children are disaggregated by age, but the individual level of specific individuals reflects only to a small extent. The study also shows that Estimulación temprana leads parents to better orientation in education, targeted child care and out-of-school lessons and also helps them with effective ways of stimulating. From the subjective point of view of parents, the contribution of Estimulación Temprana lies above all in the possibility of sharing experiences, deregistering, establishing friendly relationships, and changing educational leadership. The results of this work provide a qualitative analysis in our not known program Estimulación temprana, whose specificity lies in the orientation to the whole of child development, thus being distinguished among...

Tato diplomová práce je primárně zaměřena na problematiku projeků vývoje nového výrobku (NPD). Cílem je analyzovat problematiku vývoje nového výrobku, jakožto samostatné disciplíny projektového řízení. Dále představit a podrobněji popsat, u nás méně známý, nástroj pro podporu a koordinaci projektů PD-Trak? a analyzovat podporu jeho funkcí metodikou PMBOK. Nástroj je přímo určen pro projekty NPD. Nakonec se budu věnovat vývoji nového výrobku ve společnosti Opavia-Lu a.s. a srovnání této metodiky vývoje s metodikou PMBOK.