Manufacturing today has become a matter of the effective and efficient application of information technology and knowledge engineering. Manufacturing firms success depends to a great extent on information technology, which emphasizes the integration of the information systems used by a manufacturing enterprise. This integration is also called enterprise application integration (here the term application means information systems or software systems). The methodology for enterprise application integration, in particular enterprise application integration automation, has been studied for at least a decade; however, no satisfactory solution has been found. Enterprise application integration is becoming even more difficult due to the explosive growth of various information systems as a result of ever increasing competition in the software market. This thesis aims to provide a novel solution to enterprise application integration. The semantic data model concept that evolved in database technology is revisited and applied to enterprise application integration. This has led to two novel ideas developed in this thesis. First, an ontology of an enterprise with five levels (following the data abstraction: generalization/specialization) is proposed and represented using unified modeling language. Second, both the ontology for the enterprise functions and the ontology for the enterprise applications are modeled to allow automatic processing of information back and forth between these two domains. The approach with these novel ideas is called the enterprise semantic model approach. The thesis presents a detailed description of the enterprise semantic model approach, including the fundamental rationale behind the enterprise semantic model, the ontology of enterprises with levels, and a systematic way towards the construction of a particular enterprise semantic model for a company. A case study is provided to illustrate how the approach works and to show the high potential of solving the existing problems within enterprise application integration.

Manufacturing today has become a matter of the effective and efficient application of information technology and knowledge engineering. Manufacturing firms success depends to a great extent on information technology, which emphasizes the integration of the information systems used by a manufacturing enterprise. This integration is also called enterprise application integration (here the term application means information systems or software systems). The methodology for enterprise application integration, in particular enterprise application integration automation, has been studied for at least a decade; however, no satisfactory solution has been found. Enterprise application integration is becoming even more difficult due to the explosive growth of various information systems as a result of ever increasing competition in the software market. This thesis aims to provide a novel solution to enterprise application integration. The semantic data model concept that evolved in database technology is revisited and applied to enterprise application integration. This has led to two novel ideas developed in this thesis. First, an ontology of an enterprise with five levels (following the data abstraction: generalization/specialization) is proposed and represented using unified modeling language. Second, both the ontology for the enterprise functions and the ontology for the enterprise applications are modeled to allow automatic processing of information back and forth between these two domains. The approach with these novel ideas is called the enterprise semantic model approach. The thesis presents a detailed description of the enterprise semantic model approach, including the fundamental rationale behind the enterprise semantic model, the ontology of enterprises with levels, and a systematic way towards the construction of a particular enterprise semantic model for a company. A case study is provided to illustrate how the approach works and to show the high potential of solving the existing problems within enterprise application integration.

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The proliferation of services on the web is leading to the formation of service ecosystems wherein services interact with one another in ways not foreseen during their development or deployment. This means that over its lifetime, a service is likely to be reused across multiple interactions, such that in each of them a different interface is required from it. Implementing, testing, deploying, and maintaining adapters to deal with this multiplicity of required interfaces can be costly and error-prone. The problem is compounded in the case of services that do not follow simple request-response interactions, but instead engage in conversations comprising arbitrary patterns of message exchanges. A key challenge in this setting is service mediation: the act of retrofitting existing services by intercepting, storing, transforming, and (re-)routing messages going into and out of these services so they can interact in ways not originally foreseen. This thesis addresses one aspect of service mediation, namely service interface adaptation. This problem arises when the interface that a service provides does not match the interface that it is expected to provide in a given interaction. Specifically, the thesis focuses on the reconciliation of mismatches between behavioural interfaces, that is, interfaces that capture ordering constraints between message exchanges. We develop three complementary proposals. Firstly, we propose a visual language for specifying adapters for conversational services. The language is based on a an algebra of operators that are composed to define links between provided-required interfaces. These expressions are fed into an execution engine that intercepts, buffers, transforms and forwards messages to enact the adapter specification. Secondly, we endow such adapter specifications with a formal semantics defined in terms of Petri nets. The formal semantics is used to statically check the correctness of adapter specifications. Finally, we propose an alternative approach to service interface adaptation that does not require hard-wired links between provided and required interfaces. This alternative approach is based on the definition of mapping rules between message types, and is embodied in an adaptation machine. The adaptation machine sits between pairs of services and manipulates the exchanged messages according to a repository of mapping rules. The adaptation machine is also able to detect deadlocks and information loss at runtime.

A cardiomiopatia chagásica crônica é a consequência mais grave da Doença de Chagas, quadro infeccioso humano causado pelo protozoário Trypanosoma cruzi. Uma vez que os cardiomiocitos podem ser invadidos pelo T. cruzi, é nosso interesse averiguar se esta população estrutural reconhece o parasita in vivo através dos TLRs (Toll Like receptors). Visto que a maioria dos TLRs sinaliza através da molécula adaptadora MyD88, no presente trabalho temos estudado a participação deste elemento transdutor. Para isto fomos examinar a infecção pelo T. cruzi em camundongos F2 (Mer / MyD88flox+/+), modelo animal no qual o tratamento com a droga Tamoxifeno deve eliminar a molécula MyD88 exclusivamente nos cardiomiócitos. Resultados: em um estudo prévio, constatamos que cardiomiócitos tumorais murinos HL-1, em repouso ou após infecção pelo T. cruzi, transcrevem a molécula MyD88. A seguir, validamos o modelo experimental in vivo, ao mostrar que o tratamento com tamoxifeno dos animais F2 resulta na diminuição de MyD88 no coração, mas não no baço. Ainda, constatamos que a transcrição de MyD88 é mais intensa na aurícula do que no ventrículo, sendo igualmente abolida dos animais F2 pelo tratamento com tamoxifeno. Por outro lado, verificamos que o tamoxifeno determina um aumento da parasitemia em ambos os animais F2 e controle (MerCreMer+/+), não se observando diferenças significativamente entre estes. Finalmente, estudos preliminares mostraram que a eliminação de MyD88 nos cardiomiócitos dos animais F2 não altera significativamente o quadro de patologia (parasitismo e infiltração leucocitária) aos 10 ou 28 dias de infecção pelo T. cruzi, quando comparado ao de animais controle (MerCreMer+/+) igualmente tratados com tamoxifeno e infectados. / Chronic Chagas cardiomyopathy is the most serious consequence of Chagas Disease, caused by Trypanosoma cruzi. Cardiomyocytes are invaded by T. cruzi, it is our interest to see if this structural population in vivo recognizes the parasite through TLRs. Since most TLRs signal through MyD88, we studied in vivo participation of Myd88 in cardiomyocyte response. Treatment with tamoxifen (Tam) eliminate the MyD88 molecule exclusively from cardiomyocytes in F2 mice, which we used to understand its role on T. cruzi infection. Results: HL-1 cells, a murine cardiomyocyte tumor line, in infection with T. cruzi, transcribe the MyD88 molecule. Transcription of MyD88 is more intense in the atria than in ventricle. Tam treatment of F2 mice eliminates the MyD88 at the heart completely, but not at spleen. Tam caused increased parasitaemia, no differences were observed in the parasitaemia curve of infected F2 and MerCreMer+/+ (control) mice. Finally, MyD88 elimination in cardiomyocytes of F2 mice does not alters the pathology frame at days 10 and 28 post infection.

Istället för att arbeta enligt den traditionella vattenfallsmetoden så blir det allt vanligare att projekt använder sig av agila metoder. Det agila ramverket föreskriver att det inte ska finnas någon projektledare i agila projekt och tillför istället agila roller. Trotts att det agila ramverket menar att det inte ska finnas någon projektledare i agila projekt så visar studier att det ändå ofta finns en agil projektledare. Syftet med denna studie är att undersöka den agila projektledarens roll i agila projektEn djupare undersökning av hur den agila projektledarens roll kan se ut i ett svenskt företag utfördes genom kvalitativa intervjuer med två intervjupersoner från ett företag. Kvalitativ textanalys av tre stycken blogginlägg skrivna av agila projektledare på webbsidor har genomförts för att få en mer internationell syn på den agila projektledarrollen.Resultaten från studien visar att det finns behov av en agil projektledare i vissa agila projekt.Stora komplexa projekt som behöver mycket ledning kan ha stor nytta av en agil projektledare. Även när projektet producerar en produkt till en kund så finns det anledning till att ha en agil projektledare som ansvarar för affären med kunden och ekonomin.I studien presenterats olika roller som den agila projektledaren kan ha och viktiga egenskaper som den agila projektledaren behöver för att vara framgångsrik.

Media extenders or digital media receivers are network devices that are used to retrieve digital media files (such as music, pictures, or video) from a media server and play or show them on a TV or home theater system. A technology that is often associated with these devices is the Universal Plug and Play (UPnP) technology. This technology enables network devices to be used without requiring the user to do network configuration on it. This thesis demonstrates how a device that is normally used for receiving digital television broadcasts can be enhanced to support media extender functionality. The thesis describes the design and implementation of the technologies that are needed to accomplish this functionality. The main topics are centered around on how UPnP awareness and media rendering (decoding) are incorporated into the device.

This diploma thesis is focused on conversion of Skoda Octavia RS mark I brake system. This vehicle will be used for race use. The aim of the thesis is to design adequate components of the brake system to achieve good brake deceleration and so that the design will be correspond to hard conditions on the race track. Thesis contains complete design of hydraulic system including control and brake forces, pressures, options of brake forces management and evaluate of brake stability. Followed by the design of brake caliper adapters and the static structural analysis by FEM. The thesis contains picture and assembly drawing attachment too.

Cílem této práce je navrhnout a sestavit napájecí zdroj pro notebooky různých výrobců pro použití v osobních a nákladních automobilech a na motocyklech s výstupním výkonem až 120W. Výsledný zdroj obsahuje USB-C konektor pro podporu napájení notebooků a chytrých zařízení s podporou Power Delivery, dále USB-A konektor s podporou Quick Charge 3.0 a také 12V automobilovou zásuvku pro možnost připojení dalšího automobilového příslušenství. Napájecí zdroj dále disponuje ochranou proti přepětí a přepólování vstupního napětí a také ochranou proti přetížení jednotlivých výstupů. Součástí zařízení je také LED displej, který uživateli umožňuje pomocí vstupního rozhraní jednoduše nastavit výstupní napětí pro notebook a sledovat aktuální hodnoty všech výstupů. Pro nastavování výstupu, indikaci a ochrany je použit mikrokontroler Arduino Nano.

The master’s thesis contains a plan of hinged adapter for cord header Cornpower 8-75 of the BISO Schrattenecker Company. The adapter is designed for threshing machines New Holland. The thesis includes a comparison of the mechanisms used by competitors. Further it contains design of the entirely different mechanism, its kinematics solution of the hydraulic circuit and calculating of the strength using FEM method, including calculation of contacts. The drawing documentation is done in Catia V5 and strength calculations in NX-Ideas and Marc 2010.