We first discuss some fundamental results such as equilibria, linearization, and stability of nonlinear dynamical systems arising in mathematical modeling. Next we study the dynamics in planar systems such as limit cycles, the Poincaré-Bendixson theorem, and some of its useful consequences. We then study the interaction between two and three different cell populations, and perform stability and bifurcation analysis on the systems. We also analyze the impact of immunotherapy on the tumor cell population numerically.

The purpose of this thesis was to examine a partial differential equation to model the Tacoma Narrows bridge failure. This thesis will examine the equation developed by Lazer and McKenna to model a suspension bridge in no wind.

Tato diplomová práce je zaměřena na analýzu chování magnetopiezoelastického kmitajícího nosníku. V teoretické části jsou odvozeny diskretizované parametry, které popisují reálnou soustavu jako model s jedním stupněm volnosti. Tento model je následně použit pro kvalitativní i kvantitativní analýzu chování tohoto harvesteru. Frekvenční odezva harmonicky buzeného systému je zkoumána v dvouparametrické nebo tříparametrické analýze v závislosti na amplitudě buzení, elektrické zátěži a vzdálenosti mezi magnety. Posledně zmíněný parametr je v práci tím hlavním, proto je vliv vzdálenosti magnetů zkoumán také s pomocí bifurkačních diagramů. Tyto diagramy byly navíc použity k vytvoření oscilační "mapy", která pro každé zatěžovací podmínky ukazuje, jakou vzdálenost magnetů je třeba nastavit, aby bylo generováno nejvíce energie. Práce je doplněna o ukázky několika jevů, které mohou značně ovlivnit chování systému, pokud se nejdená o čistě harmonické buzení.

Above ground steel storage tanks are used worldwide for the storage of various liquids. EN 14015:2005, which has traditionally been used to design the tanks, does not necessarily fulfil the requirements of the Swedish Building Code. This has been underlined by hand calculation models in EN 1993-1-6:2007, EN 1993-4-2:2007 and numerical analysis using Finite Element Method (FEM). Therefore, this thesis investigates the differences between these design models and, preliminarily, the use of high-strength steel in tank shells. A 10600 m3 cylindrical steel tank of diameter 26 m and height of 21 m located in Gothenburg, Sweden is studied. The study is limited to the assessment of the stress in the shell courses due to the hydrostatic pressure from the fluid action of a filled tank, and the buckling behaviour of the shell courses of an empty tank subjected to self-weight, snow and wind loads. Particularly, models of the tank shell with a yield strength of 355 MPa are investigated in detail, while the results of the 700 MPa model are considered as preliminary study, since the material is currently not used for tank shells. An analysis of the fluid action on the tank shell courses in each of the three hand calculation models, showed that the EN 14015 model utilizes thicker courses than both Eurocodes. One benefit of the Eurocode models is that they do not limit the thickness of the shell courses, but it is still necessary to have thicker courses in the upper part of the tank in order to achieve sufficient resistance against buckling. EN 14015:2005, on the other hand, limits the minimum thickness to 6 mm for the investigated tank. Furthermore, only EN 1993-1-6 is applicable to the models with a yield strength of 700 MPa as per EN 1993-1-12 and this resulted in a uniform shell thickness of 6 mm. However, an increase in yield strength has no buckling benefits whatsoever.  Buckling is the most critical aspect as observed in this study. EN 14015 has no specific buckling calculations but uses the approach of determining the number of stiffening rings which are deemed adequate against buckling. In this study, 3 secondary stiffening rings were found to be adequate. In comparison, the results of EN 1993-4-2 are very conservative and lead to a very high and uneconomical number of stiffening rings, ranging from 30 to 52 stiffening rings depending on the reliability class. EN 1993-1-6 resulted in 6-17 stiffening rings, for reliability classes 1-3 and fabrication classes A-C. Therefore, the so-called analytical models in the Eurocodes result in a much denser spacing of stiffening rings than 14015:2005.  The buckling stresses due to the design loads were found to be lower than the yield strength of the tank shells for both hand calculation and FEM models. This means that the tank shells failed in buckling before the yield strength of the material was reached. Based on the parametric study of the EN 1993-1-6 (355 MPa) model regarding reliability class 1 and fabrication class A using FEM, the spacing of the stiffening rings can be increased up to 60 % (from 3825 mm to 6120 mm) with the variable loads also increased simultaneously up to 3.8 times before the shell buckles. Therefore, the design of future tanks using numerical analysis guarantee’s more reliability than all the aforementioned standards.  The design for buckling according to EN 14015 is only valid for a design snow load and under-pressure ≤ 1.2 KN/m2. However, according to the standard itis possible to agree to use it for larger actions or use another design model for buckling.

This work focusses on analysing the stability of the MSFR – a molten salt reactor with a fast neutron spectrum. The investigations are based on a model, which was published and studied by the Politecnico di Milano using a linear approach. Since linear methods can only provide stability information to a limited extent, this work continues the conducted investigations by applying nonlinear methods. In order to examine the specified reactor model, the system equations were implemented, adjusted and verified using MATLAB code. With the help of the computational tool MatCont, a so-called fixed-point solution was tracked and its stability monitored during the variation of selected control parameters. It was found that the considered fixed point does not change its stability state and remains stable. Coexisting fixed points or periodic solutions could not be detected. Therefore, the analysed MSFR model is considered to be a stable system, in which the solutions always tend towards a steady state.:1. Introduction 2. Molten Salt Reactor Technology 2.1. Introduction 2.2. Historical Development 2.3. Working Principle of Molten Salt Reactors 2.4. Molten Salt Coolants 2.5. Advantages and Drawbacks 2.6. Classification 2.7. Molten Salt Fast Reactor Design 3. Stability Characteristics of Dynamical Systems 3.1. Introduction 3.2. Dynamical Systems 3.3. Stability Concepts 3.3.1. Introduction 3.3.2. Lagrange Stability (Bounded Stability) 3.3.3. Lyapunov Stability 3.3.4. Poincaré Stability (Orbital Stability) 3.4. Fixed-Point Solutions 3.4.1. Stability Analysis of Fixed-Point Solutions 3.4.2. Bifurcations of Fixed-Point Solutions 3.5. Periodic Solutions 3.5.1. Stability Analysis of Periodic Solutions 3.5.2. Bifurcations of Periodic Solutions 4. Analysed Reactor System 4.1. Introduction 4.2. Specified Reactor Model 4.3. Implementation and Verification of the Linearised System of Equations 4.3.1. Linearised System of Delayed Differential Equations 4.3.2. Comparison with Reference Plots 4.3.3. Adaptation of Parameter Values 4.4. Implementation and Verification of the Nonlinear System of Equations 4.4.1. Nonlinear System of Delayed Differential Equations 4.4.2. Delayed Neutron Precursor Equation Adjustments 4.4.3. Salt Temperature Equation Adjustments 4.4.4. Nonlinear System of Ordinary Differential Equations 4.4.5. Verification of the Nonlinear System of Ordinary Differential Equations 5. Conducted Stability Analyses 5.1. Introduction 5.2. Nonlinear Stability Analysis 5.2.1. Implementation 5.2.2. Results 5.2.3. Interpretation 5.3. Linear Stability Analysis 5.3.1. Comparison Between the Linearised and Nonlinearised MSFR System of Equations 5.3.2. Stability Investigations Using a Linear Criterion 5.4. MatCont Reliability Test Using an MSBR Model 6. Conclusions and Recommendations for Future Studies / Im Fokus dieser Arbeit steht die Stabilitätsanalyse des MSFR – eines Flüssigsalzreaktors mit schnellem Neutronenspektrum. Als Grundlage wurde ein Modell verwendet, das am Politecnico di Milano erstellt und dort mittels linearer Methoden untersucht wurde. Da lineare Betrachtungen nur eingeschränkte Stabilitätsaussagen treffen können, erweitert diese Arbeit die Untersuchungen um die nichtlineare Stabilitätsanalyse. Zur Untersuchung des vorgegebenen Reaktormodells wurden die Systemgleichungen in MATLAB übertragen und verifiziert. Mithilfe der Rechensoftware MatCont wurde eine sogenannten Fixpunkt-Lösung des Modells unter der Variation ausgewählter Parameter verfolgt und deren Stabilität überprüft. Es hat sich gezeigt, dass der betrachtete Fixpunkt seinen Stabilitätszustand dabei nicht verändert und stabil bleibt. Koexistierende Fixpunkte oder periodische Lösungen konnten nicht nachgewiesen werden. Daher gilt das betrachtete MSFR-Modell als ein stabiles System, dessen Lösungen immer auf einen stationären Zustand zulaufen.:1. Introduction 2. Molten Salt Reactor Technology 2.1. Introduction 2.2. Historical Development 2.3. Working Principle of Molten Salt Reactors 2.4. Molten Salt Coolants 2.5. Advantages and Drawbacks 2.6. Classification 2.7. Molten Salt Fast Reactor Design 3. Stability Characteristics of Dynamical Systems 3.1. Introduction 3.2. Dynamical Systems 3.3. Stability Concepts 3.3.1. Introduction 3.3.2. Lagrange Stability (Bounded Stability) 3.3.3. Lyapunov Stability 3.3.4. Poincaré Stability (Orbital Stability) 3.4. Fixed-Point Solutions 3.4.1. Stability Analysis of Fixed-Point Solutions 3.4.2. Bifurcations of Fixed-Point Solutions 3.5. Periodic Solutions 3.5.1. Stability Analysis of Periodic Solutions 3.5.2. Bifurcations of Periodic Solutions 4. Analysed Reactor System 4.1. Introduction 4.2. Specified Reactor Model 4.3. Implementation and Verification of the Linearised System of Equations 4.3.1. Linearised System of Delayed Differential Equations 4.3.2. Comparison with Reference Plots 4.3.3. Adaptation of Parameter Values 4.4. Implementation and Verification of the Nonlinear System of Equations 4.4.1. Nonlinear System of Delayed Differential Equations 4.4.2. Delayed Neutron Precursor Equation Adjustments 4.4.3. Salt Temperature Equation Adjustments 4.4.4. Nonlinear System of Ordinary Differential Equations 4.4.5. Verification of the Nonlinear System of Ordinary Differential Equations 5. Conducted Stability Analyses 5.1. Introduction 5.2. Nonlinear Stability Analysis 5.2.1. Implementation 5.2.2. Results 5.2.3. Interpretation 5.3. Linear Stability Analysis 5.3.1. Comparison Between the Linearised and Nonlinearised MSFR System of Equations 5.3.2. Stability Investigations Using a Linear Criterion 5.4. MatCont Reliability Test Using an MSBR Model 6. Conclusions and Recommendations for Future Studies

Algorithms for fingerprints recognition are already known for long time and there is also an effort for their best optimization. This master's thesis is dealing with an opposite approach, where the fingerprints are not being recognized, but are generated on the minutiae position basis. Such algorithm is then free of the minutiae detection from image and enhancements of fingerprints. Results of this work are the synthetic images generated according to few given parameters, especially minutiae.

In der vorliegenden Arbeit wird die Fredholm-Methode zur semiklassischen Berechnung einzelner Eigenzustaende von Quantenabbildungen eingesetzt. Es wird gezeigt, wie auch Eigenzustaende zu entarteten Eigenwerten berechnet werden koennen. Die semiklassische Berechnung eines Eigenzustandes erfolgt mittels der Husimifunktion. Es wird gezeigt, wie das Auftreten von Bifurkationen periodischer Bahnen beruecksichtigt werden kann. Dies geschieht auch fuer den Fall von energiegemittelten Eigenzustaenden. Ebenfalls wird die Stoerung einer Quantenabbildung durch einen Punktstreuer und dessen Auswirkungen auf die semiklassische Berechnungen untersucht.

Masters thesis of Liam Farrell, under the supervision of Dr. Duncan O'Dell. Successfully defended on August 26, 2021. / Caustics are regions created by the natural focusing of waves. Some examples include rainbows, spherical aberration, and sonic booms. The intensity of a caustic is singular in the classical ray theory, but can be smoothed out by taking into account the interference of waves. Caustics are generic in nature and are universally described by the mathematical theory known as catastrophe theory, which has successfully been applied to physically describe a wide variety of phenomena. Interestingly, caustics can exist in quantum mechanical systems in the form of phase singularities. Since phase is such a central concept in wave theory, this heralds the breakdown of the wave description of quantum mechanics and is in fact an example of a quantum catastrophe. Similarly to classical catastrophes, quantum catastrophes require some previously ignored property or degree of freedom to be taken into account in order to smooth the phase divergence. Different forms of spontaneous pair-production appear to suffer logarithmic phase singularities, specifically Hawking radiation from gravitational black holes. This is known as the trans-Planckian problem. We will investigate Hawking radiation formed in an analogue black hole consisting of a flowing ultra-cold Bose-Einstein condensate. By moving from an approximate hydrodynamical continuum description to a quantum mechanical discrete theory, the phase singularity is cured. We describe this process, and make connections to a new theory of logarithmic catastrophes. We show that our analogue Hawking radiation is mathematically described by a logarithmic Airy catastrophe, which further establishes the plausibility of pair-production being a quantum catastrophe / Thesis / Master of Science (MSc)

Indiana University-Purdue University Indianapolis (IUPUI) / Physical and biological phenomena that involve oscillations on multiple time scales attract attention of mathematicians because resulting equations include a small parameter that allows for decomposing a three- or higher-dimensional dynamical system into fast/slow subsystems of lower dimensionality and analyzing them independently using geometric singular perturbation theory and other techniques. However, in most life sciences applications observed dynamics is extremely complex, no small parameter exists and this approach fails. Nevertheless, it is still desirable to gain insight into behavior of these mathematical models using the only viable alternative – ad hoc computational analysis. Current dissertation is devoted to this latter approach. Neural networks in the region of the brain called basal ganglia (BG) are capable of producing rich activity patterns. For example, burst firing, i.e. a train of action potentials followed by a period of quiescence in neurons of the subthalamic nucleus (STN) in BG was shown to be related to involuntary shaking of limbs in Parkinson’s disease called tremor. The origin of tremor remains unknown; however, a few hypotheses of tremor-generation were proposed recently. The first project of this dissertation examines the BG-thalamo-cortical loop hypothesis for tremor generation by building physiologically-relevant mathematical model of tremor-related circuits with negative delayed feedback. The dynamics of the model is explored under variation of connection strength and delay parameters in the feedback loop using computational methods and data analysis techniques. The model is shown to qualitatively reproduce the transition from irregular physiological activity to pathological synchronous dynamics with varying parameters that are affected in Parkinson’s disease. Thus, the proposed model provides an explanation for the basal ganglia-thalamo-cortical loop mechanism of tremor generation. Besides tremor-related bursting activity BG structures in Parkinson’s disease also show increased synchronized activity in the beta-band (10-30Hz) that ultimately causes other parkinsonian symptoms like slowness of movement, rigidity etc. Suppression of excessively synchronous beta-band oscillatory activity is believed to suppress hypokinetic motor symptoms in Parkinson’s disease. Recently, a lot of interest has been devoted to desynchronizing delayed feedback deep brain stimulation (DBS). This type of synchrony control was shown to destabilize synchronized state in networks of simple model oscillators as well as in networks of coupled model neurons. However, the dynamics of the neural activity in Parkinson’s disease exhibits complex intermittent synchronous patterns, far from the idealized synchronized dynamics used to study the delayed feedback stimulation. The second project of this dissertation explores the action of delayed feedback stimulation on partially synchronous oscillatory dynamics, similar to what one observes experimentally in parkinsonian patients. We employ a computational model of the basal ganglia networks which reproduces the fine temporal structure of the synchronous dynamics observed experimentally. Modeling results suggest that delayed feedback DBS in Parkinson’s disease may boost rather than suppresses synchronization and is therefore unlikely to be clinically successful. Single neuron dynamics may also have important physiological meaning. For instance, bistability – coexistence of two stable solutions observed experimentally in many neurons is thought to be involved in some short-term memory tasks. Bistability that occurs at the depolarization block, i.e. a silent depolarized state a neuron enters with excessive excitatory input was proposed to play a role in improving robustness of oscillations in pacemaker-type neurons. The third project of this dissertation studies what parameters control bistability at the depolarization block in the three-dimensional conductance-based neuronal model by comparing the reduced dopaminergic neuron model to the Hodgkin-Huxley model of the squid giant axon. Bifurcation analysis and parameter variations revealed that bistability is mainly characterized by the inactivation of the Na+ current, while the activation characteristics of the Na+ and the delayed rectifier K+ currents do not account for the difference in bistability in the two models.

We consider the Volter-Salnikov model describing the dynamics of the flow chemical reactor. In the work, a study of deterministic model was performed, deterministic system attractors were defined, bifurcation diagram was constructed. For stochastic model, we analyzed a response of attractors (equilibria and cycles) on sensitivity to noise. With the help of confidence domains, a geometrical description of the dispersion of random states was given, noise-induced transitions were investigated, and of critical values of the noise intensity were estimated. We have constructed a feedback regulator that allows to provide the desired stochastic sensitivity of the system. / В работе рассматривается модель Вольтера-Сальникова, описывающая динамику проточного химического реактора. В работе было проведено исследование детерминированной модели, определены детерминированные аттракторы системы, построена бифуркационная диаграмма. Для стохастической модели проведен анализ аттракторов системы (равновесий и циклов) на чувствительность к шуму. С помощью доверительных областей было дано геометрическое описание областей рассеивания случайных состояний. С помощью доверительных областей исследованы индуцированные шумом переходы, проведена оценка критических значений интенсивности шума. В работе построен управляющий регулятор, позволяющий обеспечить в системе желаемую стохастическую чувствительность.