Global ETD Search

11	Isolierung und Strukturaufklärung neuer Naturstoffe aus Bakterien und endophytischen Pilzen durch chemisches Screening / Isolation and structure elucidation of new natural products from bacteria and endophytic fungi by chemical screening Bitzer, Jens 29 June 2005 (has links) No description available. 540 Chemie Mathematics and Computer Science Naturstoffe Sekundärmetaboliten Antibiotika Strukturaufklärung Actinomyceten Streptomyceten endophytische Pilze chemisches Screening OSMAC Actinomycine Chaetoglobosine Desoxytalose Aminophenoxazone Spiroverbindungen Polyketide natural products secondary metabolites antibiotics structure elucidation actinomycetes streptomycetes endophytic fungi chemical screening OSMAC actinomycin chaetoglobosin deoxytalopyranoside aminophenoxazone spiro compounds polyketides 35.50 35.25 SXE 000: Naturstoffe {Biochemie}
12	Strukturaufklärung der Phenalinolactone und Beiträge zur Biosynthese der Hexacyclinsäure / structure elucidation of phenalinolactones and contributions to the biosynthesis of hexacyclinic acid Meyer, Sven Wolfgang 21 January 2004 (has links) No description available. Mathematics and Computer Science Phenalinolactone NMR Actinomyceten Sekundärmetaboliten Naturstoffe chemisches Screening OSMAC Brasilicardin Biosynthese Hexacyclinsäure FR182877 Diels-Alderase Strukturaufklärung Terpen 540 Chemie phenalinolactones NMR actinomycetes secondary metabolites natural products chemical screening OSMAC brasilicardin biosynthesis hexacyclinic acid FR182877 diels-alderase structure elucidation terpene 35.50 35.25
13	Struktur und Biosynthese von Collinolacton aus Streptomyces sp. und Beiträge zum Screening neuer Wirkstoffe / Structure and biosynthesis of collinolactone from Streptomyces sp. and contributions to the screening of new active agents Hoffmann, Luise 03 May 2006 (has links) No description available. 540 Chemie Mathematics and Computer Science Streptomyceten extremophile Mikroorganismen Naturstoffe chemisches Screening Sekundärmetaboliten Biosynthese Collinolacton NMR Strukturaufklärung Polyketide Rotamere Baeyer-Villiger-Monooxygenase Cyclodecatrien monoastraler Spindeltyp 1-O-Acylrhamnopyranoside Shikimisäure Biosyntheseweg streptomycetes extremophilic microorganisms natural products chemical screening secondary metabolites biosynthesis collinolactone NMR structure elucidation polyketides rotamers Baeyer-Villiger monooxygenase cyclodecatrien mono-astral spindle 1-O-acylrhamnopyranosides shikimi pathway 35.50 35.25
14	DISTINCT ROLES OF THE aD HELIX IN aCAMKII ACTIVATION CHARACTERIZED USING A DE NOVO MUTATION FROM CHILDREN WITH LEARNING DISABILITIES Walter Saide (16650807) 07 August 2023 (has links) <p>This dissertation describes the effects of a <i>de novo</i> mutation of CaMKII found in children with learning disabilities and describes its effect on catalytic activity. We develop a malachite green assay for the measurement of CaMKII activation and use it for high-throughput chemical screening to identify CaMKII inhibitors and enhancers. We also propose a new mechanism of regulation of CaMKII activity by ADP.</p><p><br></p> Cell neurochemistry Enzymes Basic pharmacology Biologically active molecules Biomolecular modelling and design Proteins and peptides Catalysis and mechanisms of reactions Reaction kinetics and dynamics CaMKII α learning and memory impairment calmodulin calcium signaling kinase activity medicinal chemistry molecular pharmacology enzyme kinetics western blotting biochemistry molecular modeling high throughput chemical screening assay development protein structure enzyme coupled assays malachite green assay cellular biology fluorescence microscopy hplc lc-ms/ms autophosphorylation ATP:ADP ratios

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