Aceitando que existe um tempo lingüístico distinto do tempo físico ou do tempo cronológico, este trabalho visa o estudo do sistema temporal no español utilizando como modelo teórico as propostas de José Luiz Fiorin em As astúcias da enunciação. Desde o ponto de vista da teoria semiótica, adotada no presente trabalho, o sentido constrói-se por um percurso gerativo em três níveis: fundamental, narrativo e discursivo. A enunciação, como ato produtor de um enunciado, é a instância encarregada de instaurar no nível discursivo as categorias de pessoa, tempo e espaço. A partir do momento da enunciação estabelecem-se três momentos de referência, um momento de referência concomitante e dois não concomitantes com o momento da enunciação, o momento de referência da anterioridade e o momento de referência da posterioridade. Por sua vez cada um desses momentos de referência desdobram-se em momentos do acontecimento, igualmente concomitantes e não concomitantes (anteriores e posteriores). Os tempos verbais que exprimem a relação de concomitância configuram o sistema enunciativo e os tempos que explicam a relação de não concomitância com o momento da enunciação conformam o sistema enuncivo. São estudadas as relações dos tempos verbais do español a respeito do momento da enunciação e as diferentes posições que ocupam nos sistemas tanto enuncivo quanto enunciativo, os usos fundamentais e as possíveis neutralizações em determinados contextos ou em função da intenção do enunciador. A verificação do modelo teórico se faz extensiva às mudanças ocorridas tanto no estilo direto, o narrador delega a voz a um interlocutor, quanto no estilo indireto, na passagem de dois momentos de enunciação para um só. Não serão esquecidas as correlações temporais e as relações que os tempos do subjuntivo estabelecem com o verbo principal e, portanto, com o momento de referência dele. / Accepting there is a linguistic tense different from physical or chronological time, this work aims the studying of Spanish time system by using the theoretical model proposed by José Luiz Fiorin in his As astúcias da enunciação. From the point of view of Semiotic theory, adopted in this work, the meaning is constructed by a generative process in several levels, fundamental, narrative and discursive. Enunciation, as a producer fact of a statement, is the instance in charge to initiate in a discursive level the categories of person, time and space. From the moment of enunciation they are created three moments of reference: one moment of concomitance reference and two non-concomitance with the moment of enunciation, the moment of anterior reference and the moment of posterior reference. At the same time, each one of these moments of reference is separated into moments of occurrence, equally concomitance and nonconcomitance (anterior and posterior). The verbal tenses that express the relationship of concomitance configure the enunciative system and verbal times express the relationship of not-concomitance configure the enuncive system. First, they will be studied the relationship of Spanish verbal tenses regarding the moment of the enunciation and different positions they occupy in the systems both enuncive and enunciative. Second, they will be also studied the fundamental uses and possible verbal neutralizations in specific contexts or depending of the writer´s intention. Finally, the verification of Fiorin model is extended to the changes done in the direct style, when the narrator delegates the voice to one interlocutor, as much as in the indirect style, when the two moments of enunciation become just one. They will not been forgotten time correlations and the relationship of the subjunctive tenses establish with the main verb; therefore, with the moment of its reference.

Aceitando que existe um tempo lingüístico distinto do tempo físico ou do tempo cronológico, este trabalho visa o estudo do sistema temporal no español utilizando como modelo teórico as propostas de José Luiz Fiorin em As astúcias da enunciação. Desde o ponto de vista da teoria semiótica, adotada no presente trabalho, o sentido constrói-se por um percurso gerativo em três níveis: fundamental, narrativo e discursivo. A enunciação, como ato produtor de um enunciado, é a instância encarregada de instaurar no nível discursivo as categorias de pessoa, tempo e espaço. A partir do momento da enunciação estabelecem-se três momentos de referência, um momento de referência concomitante e dois não concomitantes com o momento da enunciação, o momento de referência da anterioridade e o momento de referência da posterioridade. Por sua vez cada um desses momentos de referência desdobram-se em momentos do acontecimento, igualmente concomitantes e não concomitantes (anteriores e posteriores). Os tempos verbais que exprimem a relação de concomitância configuram o sistema enunciativo e os tempos que explicam a relação de não concomitância com o momento da enunciação conformam o sistema enuncivo. São estudadas as relações dos tempos verbais do español a respeito do momento da enunciação e as diferentes posições que ocupam nos sistemas tanto enuncivo quanto enunciativo, os usos fundamentais e as possíveis neutralizações em determinados contextos ou em função da intenção do enunciador. A verificação do modelo teórico se faz extensiva às mudanças ocorridas tanto no estilo direto, o narrador delega a voz a um interlocutor, quanto no estilo indireto, na passagem de dois momentos de enunciação para um só. Não serão esquecidas as correlações temporais e as relações que os tempos do subjuntivo estabelecem com o verbo principal e, portanto, com o momento de referência dele. / Accepting there is a linguistic tense different from physical or chronological time, this work aims the studying of Spanish time system by using the theoretical model proposed by José Luiz Fiorin in his As astúcias da enunciação. From the point of view of Semiotic theory, adopted in this work, the meaning is constructed by a generative process in several levels, fundamental, narrative and discursive. Enunciation, as a producer fact of a statement, is the instance in charge to initiate in a discursive level the categories of person, time and space. From the moment of enunciation they are created three moments of reference: one moment of concomitance reference and two non-concomitance with the moment of enunciation, the moment of anterior reference and the moment of posterior reference. At the same time, each one of these moments of reference is separated into moments of occurrence, equally concomitance and nonconcomitance (anterior and posterior). The verbal tenses that express the relationship of concomitance configure the enunciative system and verbal times express the relationship of not-concomitance configure the enuncive system. First, they will be studied the relationship of Spanish verbal tenses regarding the moment of the enunciation and different positions they occupy in the systems both enuncive and enunciative. Second, they will be also studied the fundamental uses and possible verbal neutralizations in specific contexts or depending of the writer´s intention. Finally, the verification of Fiorin model is extended to the changes done in the direct style, when the narrator delegates the voice to one interlocutor, as much as in the indirect style, when the two moments of enunciation become just one. They will not been forgotten time correlations and the relationship of the subjunctive tenses establish with the main verb; therefore, with the moment of its reference.

No description available.

The study is designed as a prospective clinical trial. Patients with histologically proven head and neck cancer treated by curative radiotherapy were included. The aim of this study was to investigate the relationship between pretreatment or posttreatment nutritional status and overall surival or locoregional / distant control. Pretreatment and posttreatment nutritional status was evaluated by body weight, body mass index, total serum protein, albumin, prealbumin, transferin and cholinesterase. Univariete and multivariete regression analyses were applied for prognostic factors associated with survival or tumor control. In this study we demonstrated, that poorer nutritional status prior curative radiotherapy, has a negative impact on subsequent control of cancer. The most sensitive parameter was serum cholinesterase. Serum cholinesterase  108 kat/l was the independent negative prognostic factor for both locoregional and distant tumor control. Results of this study indicate the need for intensive nutritional support before starting of curative treatment.

abstract: With improvements in technology, intensive longitudinal studies that permit the investigation of daily and weekly cycles in behavior have increased exponentially over the past few decades. Traditionally, when data have been collected on two variables over time, multivariate time series approaches that remove trends, cycles, and serial dependency have been used. These analyses permit the study of the relationship between random shocks (perturbations) in the presumed causal series and changes in the outcome series, but do not permit the study of the relationships between cycles. Liu and West (2016) proposed a multilevel approach that permitted the study of potential between subject relationships between features of the cycles in two series (e.g., amplitude). However, I show that the application of the Liu and West approach is restricted to a small set of features and types of relationships between the series. Several authors (e.g., Boker & Graham, 1998) proposed a connected mass-spring model that appears to permit modeling of more general cyclic relationships. I showed that the undamped connected mass-spring model is also limited and may be unidentified. To test the severity of the restrictions of the motion trajectories producible by the undamped connected mass-spring model I mathematically derived their connection to the force equations of the undamped connected mass-spring system. The mathematical solution describes the domain of the trajectory pairs that are producible by the undamped connected mass-spring model. The set of producible trajectory pairs is highly restricted, and this restriction sets major limitations on the application of the connected mass-spring model to psychological data. I used a simulation to demonstrate that even if a pair of psychological time-varying variables behaved exactly like two masses in an undamped connected mass-spring system, the connected mass-spring model would not yield adequate parameter estimates. My simulation probed the performance of the connected mass-spring model as a function of several aspects of data quality including number of subjects, series length, sampling rate relative to the cycle, and measurement error in the data. The findings can be extended to damped and nonlinear connected mass-spring systems. / Dissertation/Thesis / Masters Thesis Psychology 2019

The research concerning eating disorders and concomitant conditions shows that anorexia nervosa and bulimia nervosa are serious disorders that pose many diagnostic and therapeutic challenges to mental health and nutrition professionals. Most psychologists and nutritionists receive broad-based training that likely only superficially touches upon the importance of these diagnostic issues. Nevertheless, effective treatment planning requires that diagnostic issues and concomitant conditions be evaluated and incorporated into the diagnosis and treatment of eating disorders. Thus, there is an increasing need for specialized training in order to better evaluate and treat the complicated clinical picture presented by eating disorder clients. However to date, no systematic training package has been available to meet this training need. The present study was designed to fulfill this need by developing and initially validating an expert system-based, computer-assisted training program (ES-CAT). The initial validation involved comparing the mean overall post-test scores of 56 subjects. Subjects were randomly assigned to one of three groups [i.e., expert system-based, computer assisted trainer (ES-CAT), expert system-based trainer without computer guidance (ES), and traditional self-study (SS)]. The ES-CAT was shown to be more effective in training subjects in the diagnosis and treatment of eating disorders than either an expert system-based trainer without computer guidance (ES) or a traditional method of training (SS). Indeed, subjects who used the ES-CAT showed large gains in knowledge and mastery of the material at better than 85%. The addition of the computer-based guidance to the expert system trainer showed more significant gains (from a pre-test to post-test) of learning than the expert system trainer manual only. Furthermore, the expert system-based trainer without computer guidance (ES) was significantly more effective in training subjects than a traditional method of reading and studying textbooks (SS). The total training time of the ES-CAT was approximately 16 hours. Thus, a reasonable and effective means of training practitioners to better evaluate and treat the complicated clinical picture presented by eating disorder patients was developed and initially validated.

Ziel der Untersuchungen war es, klinische Befunde und Laborparameter von Kühen mit Labmagenverlagerung (LMV) zu vergleichen. Dabei wurden besonders Begleit-krankheiten berücksichtigt. Trotz standardisierter Methoden, gibt es nach der Lab-magenreposition immer wieder Fälle, in denen keine oder eine verzögerte Genesung eintritt. Inflammatorische, intraabdominale Prozesse wurden vermutet, konnten aber nur schwer diagnostiziert werden. Deshalb galt der Untersuchung des Bauchpunkta-tes und der Peritonitisdiagnostik besonderes Interesse. In die Untersuchung gingen 100 Kühe mit LMV ein. Zum Zeitpunkt der OP und bei der Nachuntersuchung nach 7-12 Tagen wurden Blut und Bauchpunktatproben ent-nommen. Die Blutproben dienten der hämatologischen Untersuchung und der Analy-se des Energiestoffwechsels (FFS, BHB, Bilirubin, Cholesterol), des Proteinstoff-wechsels (Gesamtprotein, Albumin, Haptoglobin, Harnstoff, Creatinin), der Leber-funktion (GLDH, GGT, AST, LDH) und des Mineralstoffwechsels (Ca, K, Mg, Cl, Na, P, Fe). Das Bauchpunktat wurde zytologisch, bakteriologisch (Gram-Färbung) sowie klinisch-chemisch (Protein, Albumin, Harnstoff, Glucose, Cholesterol, Haptoglobin, AP, AST, CK, LDH) analysiert. Statistisch wurden die Gruppen LMV-links (n=80), LMV-rechts (n=20) und LMV-gesamt Gruppe (n=100) sowie die Gruppen ohne Begleitkrankheiten (n=31), Metritis (n=38), Erkrankungen des Bewegungsapparates (n=31), Mastitis (n=19), Enteritis (n=11), Pneumonie (n=6), Peritonitis (n=4) und Kühe mit Geburtsverletzung (n=3) zum Zeitpunkt der OP und zum Zeitpunkt der Nachuntersuchung verglichen. Die Laborparameter im Bauchpunktat zeigten zum Zeitpunkt der OP keine auffälligen Abweichungen. Stärkere Veränderungen konnten bis zur Nachuntersuchung 7-12 Tage p. OP festgestellt werden. Die zur Peritonitisdiagnostik relevanten Parameter Gesamtleukozyten, neutrophile Granulozyten, eosinophile Granulozyten und Ge-samtprotein stiegen an (p<0,0001). Die Befunde der verschiedenen Begleitkrankhei-ten unterschieden sich nur unwesentlich (p>0,05). Der Nachweis von Bakterien im Bauchpunktat korrelierte nicht mit der Begleitkrankheit Peritonitis. Der bei der hämatologischen Blutanalyse bestehende hohe Anteil an Kernlinksver-schiebungen zum Zeitpunkt der OP hing mit den diagnostizierten Begleitkrankheiten zusammen. Der Anteil stabkerniger Granulozyten lag bei allen Begleitkrankheiten Gruppen über dem Referenzwert, der der Metritis Gruppe mit 0,53 G/l signifikant (p<0,05) höher als bei der Gruppe ohne Begleitkrankheit (0,18 G/l). Der Energiestoffwechsel der Kühe mit LMV war stark belastet. Die FFS- und BHB-Konzentrationen waren zurzeit der OP über den Referenzwert erhöht, fielen aber bis zur Nachuntersuchung bis in den Normbereich (p<0,0001). Der Vergleich der Be-gleitkrankheiten brachte keine signifikanten Differenzen. Zurzeit der OP wurden für beide LMV-Gruppen über den Referenzwert erhöhte Hap-toglobinkonzentrationen sowie Creatinkinase-, AST- und LDH- Aktivitäten bestimmt. Kalium und Magnesium zeigten bei Kühen mit LMV zum Zeitpunkt der OP erniedrigte Konzentrationen. Die Kaliumkonzentrationen beider LMV-Gruppen normalisierten sich bis zur Nachuntersuchung (p<0,0001). Der Vergleich der Stoffwechselparameter bei den unterschiedlichen Begleitkrankhei-ten zurzeit der OP ergab nur für die Metritis-Gruppe gegenüber der Gruppe ohne Be-gleitkrankheit signifikante Differenzen: niedrigere Harnstoff- (p<0,05), Cholesterol-, Albumin- und Magnesiumkonzentrationen (p<0,0001) sowie höhere Bilirubin- und Haptoglobinkonzentrationen (p<0,05). Schlussfolgernd ist festzustellen: 1. Kühe mit LMV leiden häufig an weiteren Erkrankungen, in erster Linie an Metritis und an Erkrankungen des Bewegungsapparates. 2. Häufig konnte eine Entgleisung des Energiestoffwechsels mit erhöhten FFS- und BHB-Konzentrationen festgestellt werden, die sich nach Reposition des verlagerten Organs unter Therapie wieder normalisierte. 3. Die Anzahl der Begleitkrankheiten hatten keine statistisch nachweisbaren Auswirkungen auf den Behandlungserfolg der operierten LMV-Kühe, wobei für die Rekonvaleszenz der Kühe eine, den jeweiligen Begleitkrankheiten angepasste Behandlung von Bedeutung ist. Die Begleitkrankheit Metritis zeigte die deutlichsten Abweichungen bei der Untersuchung der Stoffwechselparameter. Es konnte kein statistischer Zusammenhang zwischen der Begleitkrankheit Peritonitis und der verstorbenen Patientengruppe nachgewiesen werden. 4. Die zur Peritonitisdiagnostik gewonnene Bauchhöhlenflüssigkeit war post OP starken Veränderungen unterworfen. Diese Veränderungen zeigten sich vor allem in stark gestiegenen Leukozytenzahlen und erhöhten Proteinkonzentrationen.

The folio of compositions and critical commentary documents a major practice-led research project that was carried out from 2003-09 on the topic of ‘electroacoustic music with moving images’. The written report analyses and expands on the creative works by supplying detailed information concerning the ‘process’ of composing for the genre, and the ‘language’ of audiovisual media pairing. Sixteen extracts of creative work featuring specific qualities of language are also provided as a means of focussing discussion points. The folio of compositions is comprised of four creative works: Shifting Ground (2005), Mouth Piece (2008), Abide With Me (2009), and Eyepiece (2009), which present a one-hour audiovisual programme. The series was premiered in a special concert Seeing With Ears: Video Works By John Coulter as part of the proceedings of the New Zealand Electroacoustic Music Symposium (NZEMS) 2-4 September 2009, School of Music, University of Auckland, New Zealand. Part 1 of the thesis seeks to illuminate a general process of creative practice that is relevant to all forms of studio-based composition. Three frameworks are examined: those that contain singular creative tasks, those that contain multiple tasks, and those that contain multiple creative projects. A 3-tiered model of reflective practice is then offered, and procedures common to all electroacoustic composers are discussed. The action research paradigm is then presented, followed by domain-specific guidelines for undertaking research. Key differences between ‘composing’ and ‘researching’ are examined, and principles of conducting practice and research simultaneously are submitted. For those working in studio-based settings, the study provides a model, and a vocabulary for discussing his/her creative process, as well as procedural guidelines for contributing to expert domain knowledge through practice-led research. Part 2 of the thesis directly addresses a common paradox faced by composers working with sounds and moving images. On one hand, audiovisual materials appear to offer the possibility of complementing one another - of forming a highly effective means of communicating artistic ideas, and on the other, they appear to carry the risk of detracting from one another – of deforming the musical language that he/she has worked so hard to create. The study seeks to transcend this paradox through the identification of audiovisual materials that function in different ways. Examples of creative work are offered to illustrate more general points of language, a model for classifying media pairs is put forward, and practical methods of audiovisual composition are proposed. The narrow findings of the study offer a vocabulary for discussing the functionality of audiovisual materials, detailed methods of media pairing and techniques of parametric alignment, while the wider findings extend to associated domains such as live electronic music, and hyper-instrument design. In summary, the study recognises both creative works and written works as knowledge-bearing documents. Succinctly stated, the essential research findings are presented and supported by both phenomenological and nominal means - through aspects of creative works that make themselves apparent during the listening process, and through retrospective logical enquiry.

La comorbidité d’une consommation problématique de psychotropes (CPP) et de symptômes de stress post-traumatique (SSPT) toucherait une personne sur deux dans les centres de réadaptation en dépendance (Woo et Vedelago, 2012). Or, pour certains auteurs, certaines stratégies d’adaptation utilisées par les individus présentant cette double problématique pourraient diminuer le risque de développer et maintenir des difficultés, alors que d’autres stratégies augmenteraient ces mêmes difficultés (Lalonde et Nadeau, 2012). Ce mémoire a pour objectifs a) de décrire et comparer le type et la diversité des stratégies d’adaptation au stress utilisées par les adultes, hommes et femmes, présentant à la fois une CPP et des SSPT et b) d’identifier la présence d’association entre les types de stratégies d’adaptation au stress (recherche de soutien social, fuite/évitement, résolution de problèmes, réévaluation positive) utilisées et les échelles de SSPT (auto-perturbation, stress post-traumatique, externalisation, somatisation) selon le genre tout en contrôlant pour l’âge et le moment de survenue du traumatisme (enfance, âge adulte). Méthodologie. L’échantillon de convenance de la présente étude est composé de 75 adultes (38 hommes et 37 femmes) présentant une consommation problématique de psychotropes, ayant été victimes d’un traumatisme interpersonnel et rapportant des symptômes de stress post-traumatique. Ceux-ci proviennent tous du programme Maître de sa vie offert au Centre de réadaptation Portage-Québec. Le DÉBA-A/D (Tremblay, Rouillard et Sirois, 2001, Tremblay et Blanchette-Martin, 2009), le Trauma Symptoms Inventory-2 (Brière, 2011) et le Ways of coping questionnaire (revised) (Folkman et Lazarus, 1985) sont les instruments de mesure utilisés. Des statistiques descriptives et comparatives bivariées ainsi que des régressions linéaires ont été réalisées pour répondre aux objectifs de l’étude. Résultats. Les résultats obtenus indiquent que les hommes utilisent plus fréquemment que les femmes la stratégie de résolution de problèmes. De plus, lorsqu’ils présentent une forte sévérité de SSPT (auto-perturbation, de stress post-traumatique, externalisation, somatisation), les individus, hommes et femmes, présentant la double problématique utilisent fréquemment la stratégie de fuite/évitement. Inversement, lorsqu’ils présentent une faible sévérité de symptômes d’auto-perturbation et d’externalisation, les hommes et les femmes utilisent fréquemment les stratégies de résolution de problèmes et de réévaluation positive. Le genre n’a démontré aucun effet modérateur. Discussion. La présente étude est l’une des rares dans le domaine de la comorbidité CPP/SSPT à cibler, en proportion égale, des hommes et des femmes provenant d’une population clinique d’adultes ayant tous été victimes d’un traumatisme interpersonnel. À la lumière des résultats obtenus, les interventions auprès de cette clientèle, hommes et femmes, devraient viser à faire diminuer la fréquence d’utilisation de la stratégie de fuite/évitement et augmenter la fréquence d’utilisation des stratégies de résolution de problèmes et de réévaluation positive.

Les traumatismes spinaux (TS) touchent environ 17 810 personnes chaque année en Amérique du Nord. À la suite de ces lésions, la plupart des individus atteints vont perdre l’habilité à effectuer des mouvements simples et certains peuvent présenter des paralysies d’un ou plusieurs membres. Également, ces patients vont souffrir de troubles du sommeil, de détresse émotionnelle (anxiété et dépression) et de déficits cognitifs (mémoire). L’occurrence d’un traumatisme crânien (TC) concomitant est sous-estimée et sous-diagnostiquée dans 12.4 à 74% des patients TS, pouvant affecter considérablement la réhabilitation post-traumatisme. Bien que les soins prodigués actuellement permettent une certaine récupération après TS ou TC, il semble nécessaire de développer des thérapies adaptées dans le cadre des TS-TC concomitants. Afin de combler ce manque de connaissances après TS-TC concomitant, nous avons développé un nouveau modèle animal de TS-TC concomitant. En utilisant des approches comportementales et électrophysiologiques, nous avons examiné l’impact d’un TS-TC concomitant sur les fonctions motrices, le sommeil, l’état émotionnel et les capacités cognitives. Un groupe de rats recevant un TS-TC concomitant a été comparé avec un groupe ne recevant qu’un TS seul et un groupe contrôle (SHAM), recevant une laminectomie et une craniotomie sans TS et TC. La locomotion globale et le sommeil ont été évalués à chaque semaine pendant un mois par le test de session en arène ouverte et par électroencéphalographie pour évaluer l’architecture du sommeil, l’analyse spectrale des états de vigilance, incluant spécifiquement la dynamique de l’activité delta en sommeil sans mouvement rapide des yeux (sommeil NREM). L’état émotionnel et les capacités cognitives ont été testés 6 semaines post-traumatisme. L’anxiété et la dépression ont été testées en arène ouverte et par le test de préférence au sucrose respectivement. La mémoire de travail et la mémoire spatiale ont été testées par le test du labyrinthe en Y et par le test de reconnaissance spatiale d’objets respectivement. Le TS-TC et le TS seul ont induit des déficits moteurs en comparaison au groupe SHAM. La durée et la qualité de l’éveil et du sommeil n’ont pas été affectées par le TS seul ou le TS-TC concomitant, malgré une tendance à la hause de l’activité spectrale et de la dynamique de l’activité delta en sommeil NREM après TS-TC. Ni le TS-TC ou le TS seul n’a affecté l’état émotionnel. Seule la mémoire de travail a été affectée après TS-TC en comparaison aux groupes SHAM et TS seul. Les résultats obtenus suggèrent que la mémoire de travail pourrait être considérée comme un potentiel biomarqueur de lésion concomitante de la moelle épinière et du cerveau. De plus amples expériences seront nécessaires afin de décrire complétement ce nouveau modèle animal de TS-TC concomitant comme d’une part, la réalisation de mesures comportementales spécifiques dans les phases aigue et chronique post-traumatisme et d’autre part, une mesure de la neuro-inflammation et de la plasticité par immunohistochimie au niveau de l’hippocampe. Le développement de ce nouveau modèle animal va permettre la création et l’adaptation d’outils diagnostiques et thérapeutiques pour les patients présentant des TS-TC concomitants. / Spinal cord injuries (SCI) affect 17,810 people in North America every year. In this condition, most individuals will lose the ability to perform simple motor actions and will additionally suffer from sleep disturbances, emotional distress (anxiety and depression) and cognitive impairments (memory). The occurrence of traumatic brain injury (TBI) in SCI population is underestimated and missed-diagnosed in 12.4 to 74% of SCI patients, impeding the implementation of optimal rehabilitation strategies and drug therapies. Although specialized care is critically needed to improve rehabilitation outcomes in these patients, specialized dual diagnosis care and evidence-based approaches for treatment are currently lacking. To address this knowledge gap, we developed and characterized a novel rodent model of concomitant TBI and SCI. Using a combination of behavioral and electrophysiological techniques, we examined the impact of concomitant TBI and SCI on motor function, sleep, emotional state, and cognition. A group of rats receiving concomitant TBI and SCI were compared with control groups that received SCI only or surgical procedures without injuries (SHAM group). Global locomotion and sleep were evaluated each week for one month by using the open-field test and electroencephalography to evaluate sleep architecture, the spectral composition of vigilance states, including delta activity during non-rapid eye movement (NREM) sleep. Emotional states and cognition were assessed at 6 weeks after surgery. Anxiety and depression were tested using the open-filed and sucrose preference tests, respectively. Working memory and spatial memory were evaluated by Y Maze test and spatial object recognition test, respectively. We found that concomitant TBI-SCI and SCI alone both impacted locomotor abilities, by comparison to the intact state. The duration and quality of wakefulness and sleep were not significantly affected by SCI or TBI-SCI, despite spectral analysis showing a tendency for TBI-SCI to increase NREM sleep delta activity. Neither concomitant TBI SCI nor SCI significantly impacted anxiety and depressive-like behaviors in comparison to the SHAM group. By contrast, working memory was significantly impaired after TBI-SCI but was preserved in SHAM and SCI groups. This result suggests that working memory could potentially be used as a biomarker of these concomitant injuries. Further experiments are needed to fully characterize this novel animal model. This includes performing more specific behavioral tests in the acute and chronic stages after injury. Also, immunochemistry experiments directed on molecular markers of neuro-inflammation and plasticity are needed. This novel animal model will be useful to create and adapted diagnosis and therapeutic tools for TBI-SCI patients.