In this experiment it was investigated how scent affect the memory. Encoding information in the same context as retrieving it has been suggested to be beneficial for memory, earlier research has mostly explored how environmental contextual cues affects the memory. In this research the contextual cue was created by a presentation of a scent. The participants were presented with two lists of words, during the encoding of the first list all the participants were presented with a scent, half of the group was directed to forget the first list straight after encoding and the other half to keep remembering the list. For the second list no one was presented with a scent. In the retrieval of both lists half of each group was reinstated with the scent they were presented with at encoding and the other half without the scent (control group). The data were analysed with univariate ANOVAs and significant effects were followed up with independent-samples t-test. The results were that participants that were reinstated with the scent were thought to remember more than the others, however there was only a significant difference in the forget condition with reinstatement, where they remembered less than in the other conditions.

Previous evidence has shown that older adults may have specific declines in prefrontal cortex (PFC)-mediated processes supported source memory retrieval, such as strategic retrieval and post-retrieval monitoring. This decline may manifest in the form of attenuated late-frontal ERP effects. Behavioral research suggests that explicitly integrating a target context, or source, with a stimulus during encoding will improve subsequent source memory performance for both younger and older adults. Explicit item-feature binding instructions during encoding may alleviate source memory impairments, in part, by reducing the need for strategic processing during episodic retrieval. The present ERP study investigated whether explicit direction of attention toward item-feature integration may reduce age-related deficits in source memory by alleviating the necessity of frontally-mediated strategic processing at retrieval. Results demonstrated that explicit direction of attention improved source memory accuracy for both young and older adults, but older adults benefited less than the young, indicating additional age-related deficits. ERPs revealed that explicit encoding support attenuated post-retrieval monitoring effects in the young. In the old, explicit encoding instruction resulted in earlier onset of early frontal effects, possibly related to familiarity. Results suggest explicit direction of attention toward item-source integration at encoding may improve source memory by alleviating the need for strategic retrieval, but age-related deficits persist.

Amygdala kindling is commonly used to study the mechanisms involved in epileptogenesis, with long-term amygdala kindling providing a useful model of the behavioural disturbances such as heightened anxiety that can occur between epileptic seizures. The purpose of this thesis was to determine whether increased fear behaviours exhibited by long-term amygdala kindled rats are reflective of previously observed kindling-mediated alterations in the hippocampus. As the hippocampus plays an integral role in contextual learning, the ability of the animals to habituate to a novel environment was evaluated, in order to determine if the rats displayed impairments in this hippocampal-dependent function. In Experiment 1, long-term kindled rats demonstrated consistently elevated exploration and fear over repeated exposure to an initially novel open field, indicating impaired habituation. In Experiment 2, all kindled rats showed elevated exploration and an inability to form a home base in relation to static visual cues, again demonstrating an inability to habituate over repeated exposures to the initially novel environment. Rats that had received 30 or 60 stimulations demonstrated hyperexploratory behaviour and elevated fear, although this behaviour did dissipate to a certain degree by the final day of testing. Long-term kindled rats, having received 99 stimulations, demonstrated extremely heightened fear behaviours that interfered with normal exploration, home base formation and habituation. These fear behaviours included high levels of freezing, disorganized running, and purposive jumping from the open field. Taken together, these results indicate that long-term amygdala kindling does produce deficits in habituation to an initially novel environment. As habituation necessarily involves the hippocampal-dependent roles of contextual learning and memory, the current research suggests that long-term kindling does impair hippocampal function and that this may contribute to kindling-induced fear behaviours. This research may help to understand the mechanisms involved in emotional disturbances experienced by human epileptics.

Amygdala kindling is commonly used to study the mechanisms involved in epileptogenesis, with long-term amygdala kindling providing a useful model of the behavioural disturbances such as heightened anxiety that can occur between epileptic seizures. The purpose of this thesis was to determine whether increased fear behaviours exhibited by long-term amygdala kindled rats are reflective of previously observed kindling-mediated alterations in the hippocampus. As the hippocampus plays an integral role in contextual learning, the ability of the animals to habituate to a novel environment was evaluated, in order to determine if the rats displayed impairments in this hippocampal-dependent function. In Experiment 1, long-term kindled rats demonstrated consistently elevated exploration and fear over repeated exposure to an initially novel open field, indicating impaired habituation. In Experiment 2, all kindled rats showed elevated exploration and an inability to form a home base in relation to static visual cues, again demonstrating an inability to habituate over repeated exposures to the initially novel environment. Rats that had received 30 or 60 stimulations demonstrated hyperexploratory behaviour and elevated fear, although this behaviour did dissipate to a certain degree by the final day of testing. Long-term kindled rats, having received 99 stimulations, demonstrated extremely heightened fear behaviours that interfered with normal exploration, home base formation and habituation. These fear behaviours included high levels of freezing, disorganized running, and purposive jumping from the open field. Taken together, these results indicate that long-term amygdala kindling does produce deficits in habituation to an initially novel environment. As habituation necessarily involves the hippocampal-dependent roles of contextual learning and memory, the current research suggests that long-term kindling does impair hippocampal function and that this may contribute to kindling-induced fear behaviours. This research may help to understand the mechanisms involved in emotional disturbances experienced by human epileptics.