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  • About
  • The Global ETD Search service is a free service for researchers to find electronic theses and dissertations. This service is provided by the Networked Digital Library of Theses and Dissertations.
    Our metadata is collected from universities around the world. If you manage a university/consortium/country archive and want to be added, details can be found on the NDLTD website.
1

A Neuron Emulator and Headstage Circuit for Patch Clamp Setups

Wu, Yen-cheng 15 August 2012 (has links)
This thesis presents a neuron emulator and headstage circuit for patch clamp setups and provides simulation, measurement and verification results. The circuit implemented on a printed circuit board (PCB) is battery powered and portable. The emulator provides both passive (resting potential) and active (action potential) electrical properties of a live neuron as seen from a single electrode by using the headstage circuit. It can be used to test electrophysiological equipment such as current-clamp, voltage-clamp or patch-clamp amplifiers. The action potentials (APs) are generated with a voltage-dependent frequency controlled by a microcontroller implementing a firing range from -60 mV to -30 mV and firing frequency from 1 Hz to10 Hz. The charge released by firing the neuron is initially stored on a 110 pC capacitor. Compared to directly using a current or voltage source, this design results in a more realistic simulation of the APs generated by ionic currents in a live neuron. The measured results from a prototype demonstrate that the neuron emulator meets the design specifications and it is capable of performing voltage clamp and rate responsive current clamp functionality. Measured results using a commercial clamp amplifier are provided to confirm the emulator operation in a practical recording environment.
2

Optogenetic Tools for In-Vitro Neurophysiology

Norman, Olivia Rose January 2014 (has links)
No description available.
3

Distinct Modulatory Actions Enable Network Neuron Recruitment and Regulation

Fahoum, Savanna-Rae Hakam 21 July 2023 (has links)
No description available.
4

Subthreshold Oscillations and Persistent Activity Modulate Spike Output in the Rodent Dentate Gyrus

Anderson, Ross William 09 February 2015 (has links)
No description available.
5

Measuring the Acute Physiological Effects of Leptin in the Carotid Body

Pye, Richard Laurence 21 December 2015 (has links)
No description available.
6

Altered Skeletal Muscle Excitation-Contraction Coupling in the R6/2 Transgenic Mouse Model for Huntington's Disease

Miranda, Daniel R. January 2021 (has links)
No description available.

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