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DNS (Domain Name System) names contain a wide variety of information, such as geographic location, speed of the interface, type of interface, etc. However, extracting this information is challenging since this information does not have a consistent format across different ISPs (internet service providers) or even a particular ISP. We present a new tool, GINIE, which extracts useful information and some common dictionary words from a DNS name. We use three ISPs and a CAIDA (Center for Applied Internet Data Analysis) dataset to demonstrate these capabilities. Information extracted with GINIE provides valuable insight about the infrastructure of the three ISPs and shows the availability and type of information in a collection of DNS names from many ISPs that exist in a typical dataset. The embedded information from DNS names can be used (with some additional active measurements) to infer the geo-aware topology of an ISP.

This thesis is a study of Futurum.kom´s campaign "Lyssna dig rik". Futurum.kom is a regional marketing project between Länsbibliotek Sydost, Regionbibliotek Kalmar and 25 public libraries in the county of Blekinge, Kalmar and Kronoberg. The aim of the Futurum.kom project is to strengthen the role of the public library in society. "Lyssna dig rik" was a cluster group campaign with the aim of making people know about the possibilities of loaning audiobooks in libraries. The target group was lorry drivers in the age of 30-65 with the possibilities to listen to audiobooks at work. The analysis is based on the following issues:  Which were the stated goals with the "Lyssna dig rik" campaign?  Which interventions were made at the main library to achieve the stated goals with the "Lyssna dig rik" campaign?  Which became the external results of the "Lyssna dig rik" campaign?  In which way became the external results in the target area of the "Lyssna dig rik" campaign at the main library, an effect of the interventions of the cluster group and main library? The method is a case study and an evaluation study mainly based on interviews with librarians and lorry drivers. The study reveals that the majority of the interviewed lorry drivers did notice the "Lyssna dig rik" campaign. They were on the other hand already aware of the fact that audiobooks are available in libraries and they didn’t change their opinions about audiobooks and libraries as a result of the campaign.

Ce mémoire de thèse est composé de deux parties distinctes ayant comme thématique commune, les réactions de cycloisomérisation. Nous nous sommes intéressés dans un premier temps au développement d’une réaction tandem d’acétalisation / cycloisomérisation catalysée par des sels d’argents. Cette méthodologie nous a permis d’accéder sélectivement aux familles des furoquinoléines et des pyranoquinoléines. Ces composés ont été testés comme agents antipaludiques et ont donné des résultats prometteurs. Une gamme de dérivés de furoquinoléine a également donné des activités cytotoxiques intéressantes. L’étude de leur potentielle activité antitumorale s’inscrit dans le cadre d’un projet financé par la Ligue Nationale contre le Cancer. Une étude approfondie de la réaction tandem, nous a permis de mettre en évidence l’influence de composés azotés sur le comportement du sel d’argent. Cette caractéristique nous a conduits à catalyser nos réactions grâce à un complexe inusité jusqu’alors en catalyse organométallique : l’imidazolate d’argent. Dans un deuxieme temps, nous avons étudié une réaction de benzannélation catalysée par des sels de rhodium ou d’argent. La stratégie de synthèse implique des systèmes de type benzofurane, porteurs d’énynes fonctionnalisées par un éther d’énol silylé, et conduit à des dérivés de dibenzofuranes. Ces hétérocycles, connus pour être biologiquement actifs, présentent un intérêt particulier dans la chimie thérapeutique. Nous avons également travaillé sur des indoles et avons pu synthétiser des dérivés d’oxindole originaux / Among a variety of new synthetic transformations, transition-metal-catalyzed reactions are some of the most attractive methodologies for synthesizing heterocyclic compounds. In this context, two different cycloisomerization reactions are studied. We first developed an efficient and versatile access to pyranoquinoline and furoquinoline derivatives, thanks to a tandem silver-catalyzed acetalization /cycloisomerization reaction. The synthesized compounds presented interesting antimalarial activity when tested on a resistant strain of the parasite Plasmodium Falciparum. The antitumoral activity of some furoquinolines was also investigated within a project funded by the French National League Against Cancer. Interestingly, we noticed that the regioselectivity of the cyclization can be controlled depending on the type of silver catalyst used. The observed reaction regioselectivity, including also an interesting nitrogen effect, led us to develop a silver imidazolate polymer as a stable and new silver catalyst. We also described a rhodium-catalyzed benzannulation reaction of silyl-enol-ethers onto alkynes, leading to dibenzofurans derivatives. These heterocycles are well-known for their biological properties and their interest in therapeutic chemistry. Finally, we developed an original methodology for the synthesis of oxindole derivatives

In the last century, no less than five nobel prizes have been awarded for the construction of carbon-carbon bonds : The Grignard reaction (1912), the Diels-Alder reaction (1950), the Wittig reaction (1979), Olefin metathesis (2005) and palladium cross-coupling reactions (2011). The latter two are transition metal catalyzed transformations and their impact on the synthesis of pharmaceutically active compounds, bulk chemicals, fine chemicals, high tech materials as well as agricultural chemicals has been phenomenal. These reactions have changed the way the scientific community views the science of synthesis. Unlike palladium, gold has long been considered to be an expensive and inert metal and therefore, research on Au catalysis was scarse until the begining of the new millenium. Once the scientific community realized the treasure trove of reactivity that gold had to offer, the number of chemical transformations as well as total syntheses involving Au(I)/Au(III) catalysis has sky rocketed. A methodology initially developped by Toste and coworkers has shown that intramolecular addition of a silyl enol ether on alkynes proceeds via a 5-exo¬-dig¬ process. In the first part of this thesis, we will discuss how the ancilary ligand on Au(I) species can influence pathway selectivity for these cyclizations, therefore opening the door to selective 6-endo-dig cyclizations to generate fused carbocycles. With biological processes as well as other competing processes becoming ever more efficient, the future of chemical synthesis is threatened. If it is to survive, the focus of new chemical transformations will have to be on the cost and the greeness of the process. In the second part of this thesis, we will demonstrate how Ag(I) and Cu(I) complexes can offer even better 6-endo-dig¬ selectivity than analogous Au(I) complexes. Silver is about 56 times less expensive than gold, and copper is about 453 times less expensive than gold. Due to the greatly increased selectivity as well as the diminished cost of the catalysts, we have provided access to an attractive 6-endo-dig¬ cyclization process.

In the last century, no less than five nobel prizes have been awarded for the construction of carbon-carbon bonds : The Grignard reaction (1912), the Diels-Alder reaction (1950), the Wittig reaction (1979), Olefin metathesis (2005) and palladium cross-coupling reactions (2011). The latter two are transition metal catalyzed transformations and their impact on the synthesis of pharmaceutically active compounds, bulk chemicals, fine chemicals, high tech materials as well as agricultural chemicals has been phenomenal. These reactions have changed the way the scientific community views the science of synthesis. Unlike palladium, gold has long been considered to be an expensive and inert metal and therefore, research on Au catalysis was scarse until the begining of the new millenium. Once the scientific community realized the treasure trove of reactivity that gold had to offer, the number of chemical transformations as well as total syntheses involving Au(I)/Au(III) catalysis has sky rocketed. A methodology initially developped by Toste and coworkers has shown that intramolecular addition of a silyl enol ether on alkynes proceeds via a 5-exo¬-dig¬ process. In the first part of this thesis, we will discuss how the ancilary ligand on Au(I) species can influence pathway selectivity for these cyclizations, therefore opening the door to selective 6-endo-dig cyclizations to generate fused carbocycles. With biological processes as well as other competing processes becoming ever more efficient, the future of chemical synthesis is threatened. If it is to survive, the focus of new chemical transformations will have to be on the cost and the greeness of the process. In the second part of this thesis, we will demonstrate how Ag(I) and Cu(I) complexes can offer even better 6-endo-dig¬ selectivity than analogous Au(I) complexes. Silver is about 56 times less expensive than gold, and copper is about 453 times less expensive than gold. Due to the greatly increased selectivity as well as the diminished cost of the catalysts, we have provided access to an attractive 6-endo-dig¬ cyclization process.

In the last century, no less than five nobel prizes have been awarded for the construction of carbon-carbon bonds : The Grignard reaction (1912), the Diels-Alder reaction (1950), the Wittig reaction (1979), Olefin metathesis (2005) and palladium cross-coupling reactions (2011). The latter two are transition metal catalyzed transformations and their impact on the synthesis of pharmaceutically active compounds, bulk chemicals, fine chemicals, high tech materials as well as agricultural chemicals has been phenomenal. These reactions have changed the way the scientific community views the science of synthesis. Unlike palladium, gold has long been considered to be an expensive and inert metal and therefore, research on Au catalysis was scarse until the begining of the new millenium. Once the scientific community realized the treasure trove of reactivity that gold had to offer, the number of chemical transformations as well as total syntheses involving Au(I)/Au(III) catalysis has sky rocketed. A methodology initially developped by Toste and coworkers has shown that intramolecular addition of a silyl enol ether on alkynes proceeds via a 5-exo¬-dig¬ process. In the first part of this thesis, we will discuss how the ancilary ligand on Au(I) species can influence pathway selectivity for these cyclizations, therefore opening the door to selective 6-endo-dig cyclizations to generate fused carbocycles. With biological processes as well as other competing processes becoming ever more efficient, the future of chemical synthesis is threatened. If it is to survive, the focus of new chemical transformations will have to be on the cost and the greeness of the process. In the second part of this thesis, we will demonstrate how Ag(I) and Cu(I) complexes can offer even better 6-endo-dig¬ selectivity than analogous Au(I) complexes. Silver is about 56 times less expensive than gold, and copper is about 453 times less expensive than gold. Due to the greatly increased selectivity as well as the diminished cost of the catalysts, we have provided access to an attractive 6-endo-dig¬ cyclization process.

Futurum.kom is a collaborative marketing project with the aim of strengthening the internal organization of Länsbibliotek Sydost, Regionbibliotek Kalmar and the 25 public libraries within the southeast region. The project intends to externally build the brands of the public libraries in Blekinge, Kalmar and Kronobergs län. This thesis is a study and evaluation of the implementation and results of Futurum.kom’s first campaign "Låna dig rik" at a public library. The analysis is based on the following issues:  What goals does the library have with the "Låna dig rik"-campaign.  What is the feedback from the staff's experience of the users in terms of needs and demands?  In which way does the library choose to implement the marketing campaign and what role do the users have in this process?  What is the internal performance of the library's marketing campaign, what was the experience of the staff of the campaign?  What is the external result of the library's marketing campaign? The method is based on a case study of a single library, with a series of interviews and document analysis of written and electronic documents. The study reveals that the library`s main experience of the "Låna dig rik"- campaign was the marketing event held outside the library premises. By going outside the library and presenting themselves in a new situation and environment, they created new opportunities to meet the users and to build good relationships. The study also discovered that the library sought to combine the "Låna dig rik"-campaign with its own marketing strategy.

Socialtjänsten använder idag ”Barns Behov i Centrum” (BBiC) som metod för att inkludera barn inför utredningar. Eftersom barn inte har ett naturligt sätt att uttrycka känslor i skalor eller enkelt uttrycker med ord vad de tycker/känner har detta inte varit en tillförlitlig metod. För att uppnå barnens behov har en applikation skapats med ett grafiskt gränssnitt anpassat för målgruppen. Applikationens syfte är att hjälpa barnen att kommunicera genom att de får skapa personer, känslor, händelser och relationer som de själva relaterar till. Syftet med projektet är att öka deltagandet av barn inför utredningar på ett tillförlitligare sätt än tidigare men ändå utgå från BBiC som bas och göra ett användarvänligt verktyg till barn samt vuxna. Genom verktyget lockas situationer fram i barnens vardag för att se verkligheten ur deras perspektiv. ”Hur utvecklas detta verktyg för att få fram adekvat information från barnen?” och ”Vad behövs för applikationer för att nå målen som Socialtjänsten vill åstadkomma?” är frågeställningarna. 75 barn från 6 till 12 år deltog i en fältstudie som användes för att utveckla och förbättra verktyget. Då barnen använde verktyget upptäcktes därutöver olika nya problem och fel. Utan barnens medverkan skulle det vara omöjligt att anpassa verktyget till barn på bästa sätt. För att nå målen används tidigare arbeten och möten samt studier med barnhandläggarna och projektgruppen. Under mötena framgick det hur utvecklingen med applikationer skulle fortgå för att möta både barnens och deras handläggares behov på bästa och smidigaste sätt. Resultaten som baseras på tester med målgruppen visar att applikationen hjälper barn att bättre uttrycka sina känslor och olika situationer de vart med om. Forskningsprojektet pågår till december 2021 vilket innebär att ytterligare förbättringar kommer att implementeras, bland annat kommer statistik gällande hur applikationen används bli tillgängligt. / DIG-Barn

Ce mémoire de thèse est composé de deux parties distinctes ayant comme thématique commune, les réactions de cycloisomérisation. Nous nous sommes intéressés dans un premier temps au développement d'une réaction tandem d'acétalisation / cycloisomérisation catalysée par des sels d'argents. Cette méthodologie nous a permis d'accéder sélectivement aux familles des furoquinoléines et des pyranoquinoléines. Ces composés ont été testés comme agents antipaludiques et ont donné des résultats prometteurs. Une gamme de dérivés de furoquinoléine a également donné des activités cytotoxiques intéressantes. L'étude de leur potentielle activité antitumorale s'inscrit dans le cadre d'un projet financé par la Ligue Nationale contre le Cancer. Une étude approfondie de la réaction tandem, nous a permis de mettre en évidence l'influence de composés azotés sur le comportement du sel d'argent. Cette caractéristique nous a conduits à catalyser nos réactions grâce à un complexe inusité jusqu'alors en catalyse organométallique : l'imidazolate d'argent. Dans un deuxieme temps, nous avons étudié une réaction de benzannélation catalysée par des sels de rhodium ou d'argent. La stratégie de synthèse implique des systèmes de type benzofurane, porteurs d'énynes fonctionnalisées par un éther d'énol silylé, et conduit à des dérivés de dibenzofuranes. Ces hétérocycles, connus pour être biologiquement actifs, présentent un intérêt particulier dans la chimie thérapeutique. Nous avons également travaillé sur des indoles et avons pu synthétiser des dérivés d'oxindole originaux