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  • About
  • The Global ETD Search service is a free service for researchers to find electronic theses and dissertations. This service is provided by the Networked Digital Library of Theses and Dissertations.
    Our metadata is collected from universities around the world. If you manage a university/consortium/country archive and want to be added, details can be found on the NDLTD website.
51

Estudo comparativo de soluções ultra diluídas de LiCl: espectroscopia de impedância no intervalo de frequência entre 1kHz e 13MHz / Comparative studies of ultra-higt diluídas de LiCl: espectroscopy in the frequency range of 1KHz to 13MHz

Miranda, Adriana Ramos de 06 March 2008 (has links)
O objetivo principal deste trabalho, foi a caracterização física de soluções ultra diluídas de cloreto de lítio utilizando a técnica de espectroscopia de impedância, no intervalo de freqüência entre 1kHz e 13MHz. A caracterização destas soluções foi realizada, principalmente, através do estudo do comportamento da parte imaginária da impedância de soluções diluídas e dinamizadas, até concentrações de 10-30M. A comparação com a água foi realizada através do estudo de amostras de água (denominada água de referência) submetidas, rigorosamente, ao mesmo processo de diluição e dinamização pelo qual passaram as soluções, com as quais foram comparadas. Os resultados experimentais revelaram, também, que a técnica da espectroscopia de impedância constitui-se em uma boa ferramenta para a investigação da água. Um estudo detalhado sobre a temperatura de medição das soluções foi realizado e, no intervalo de freqüência explorado, o melhor protocolo de medição baseia-se em medidas feitas em uma temperatura próxima da temperatura ambiente, em uma sala climatizada. Os valores experimentais medidos da parte real e imaginária da impedância, em cada ponto de freqüência considerado, foram modelados através dos parâmetros de um circuito elétrico equivalente. Os resultados desta análise mostraram que os dados de impedância, obtidos neste trabalho para as soluções ultra diluídas e para água de referência, são modelados de forma excelente por um circuito composto de uma resistência r em série com um circuito RC (em paralelo). A resistência R, calculada através da modelagem pelo circuito equivalente, revelou-se o melhor parâmetro para caracterizar as soluções ultra diluídas de concentrações inferiores a 10-6 M, assim como as amostras de água estudadas. Diferenças efetivas foram encontradas entre as soluções ultra diluídas LiCl 15cH (correspondente a 15a centesimal hahnemanniana) e a água de referencia, e um comportamento não monotônico da impedância foi observado durante o processo de diluição e dinamização, quando as diluições 3 a 15cH foram medidas para um mesmo lote de amostras. / The impedance spectroscopy technique was applied to the physical characterization of ultra high dilutions of lithiun cloride, in the range 1kHz to 13MHz. This characterization was obtained, mainly, by investigating the behavior of the imaginary part of the impedance of diluted and dinamizated solutions, for concentrations down to 10-30M. The experimental results were compared to the ones obtained for water, which have been submitted to exactly the same process of dilution and dinamization. Preliminary tests were carried out in order to identify the best experimental conditions to be used, mainly in respect to choosing the samples\' temperature. In result, the best measuring protocol was observed to be the one in which the liquid samples were measured at room temperature, mantained practically constant by an air conditioning system. The experimental data related to the real and imaginary part of the impedance, for each frequency value, were modeled by adjusting the parameters of an equivalent electric circuit. The results of this analysis showed that the impedance values of the ultra high dilutions and of the water agree quite well with the modelling, when the circuit are composed by a resistance r in series with a RC circuit (in parallel). The resistence R, calculated through the modelling by the equivalent circuit, was the best parameter to characterize both the ultra high dilutions (concentration smaller than 10-6M) as well as the water. Clear differences were also observed when the ultra high dilutions of LiCl 15cH (corresponding to 15a centesimal dilution) were compared to the water. A non-monotonous behavior was obtained when solutions from 3 to 15cH (corresponding to the same lot of samples) were measured.
52

Estudo comparativo de soluções ultra diluídas de LiCl: espectroscopia de impedância no intervalo de frequência entre 1kHz e 13MHz / Comparative studies of ultra-higt diluídas de LiCl: espectroscopy in the frequency range of 1KHz to 13MHz

Adriana Ramos de Miranda 06 March 2008 (has links)
O objetivo principal deste trabalho, foi a caracterização física de soluções ultra diluídas de cloreto de lítio utilizando a técnica de espectroscopia de impedância, no intervalo de freqüência entre 1kHz e 13MHz. A caracterização destas soluções foi realizada, principalmente, através do estudo do comportamento da parte imaginária da impedância de soluções diluídas e dinamizadas, até concentrações de 10-30M. A comparação com a água foi realizada através do estudo de amostras de água (denominada água de referência) submetidas, rigorosamente, ao mesmo processo de diluição e dinamização pelo qual passaram as soluções, com as quais foram comparadas. Os resultados experimentais revelaram, também, que a técnica da espectroscopia de impedância constitui-se em uma boa ferramenta para a investigação da água. Um estudo detalhado sobre a temperatura de medição das soluções foi realizado e, no intervalo de freqüência explorado, o melhor protocolo de medição baseia-se em medidas feitas em uma temperatura próxima da temperatura ambiente, em uma sala climatizada. Os valores experimentais medidos da parte real e imaginária da impedância, em cada ponto de freqüência considerado, foram modelados através dos parâmetros de um circuito elétrico equivalente. Os resultados desta análise mostraram que os dados de impedância, obtidos neste trabalho para as soluções ultra diluídas e para água de referência, são modelados de forma excelente por um circuito composto de uma resistência r em série com um circuito RC (em paralelo). A resistência R, calculada através da modelagem pelo circuito equivalente, revelou-se o melhor parâmetro para caracterizar as soluções ultra diluídas de concentrações inferiores a 10-6 M, assim como as amostras de água estudadas. Diferenças efetivas foram encontradas entre as soluções ultra diluídas LiCl 15cH (correspondente a 15a centesimal hahnemanniana) e a água de referencia, e um comportamento não monotônico da impedância foi observado durante o processo de diluição e dinamização, quando as diluições 3 a 15cH foram medidas para um mesmo lote de amostras. / The impedance spectroscopy technique was applied to the physical characterization of ultra high dilutions of lithiun cloride, in the range 1kHz to 13MHz. This characterization was obtained, mainly, by investigating the behavior of the imaginary part of the impedance of diluted and dinamizated solutions, for concentrations down to 10-30M. The experimental results were compared to the ones obtained for water, which have been submitted to exactly the same process of dilution and dinamization. Preliminary tests were carried out in order to identify the best experimental conditions to be used, mainly in respect to choosing the samples\' temperature. In result, the best measuring protocol was observed to be the one in which the liquid samples were measured at room temperature, mantained practically constant by an air conditioning system. The experimental data related to the real and imaginary part of the impedance, for each frequency value, were modeled by adjusting the parameters of an equivalent electric circuit. The results of this analysis showed that the impedance values of the ultra high dilutions and of the water agree quite well with the modelling, when the circuit are composed by a resistance r in series with a RC circuit (in parallel). The resistence R, calculated through the modelling by the equivalent circuit, was the best parameter to characterize both the ultra high dilutions (concentration smaller than 10-6M) as well as the water. Clear differences were also observed when the ultra high dilutions of LiCl 15cH (corresponding to 15a centesimal dilution) were compared to the water. A non-monotonous behavior was obtained when solutions from 3 to 15cH (corresponding to the same lot of samples) were measured.
53

An evaluation of the homoeopathic drug proving of Naja Mossambica in the light of a doctrine of signatures analysis and a comparison between the proving symptons and the venom toxicology

Taylor, Liesel January 2004 (has links)
Thesis (M.Tech.: Homoeopathy)-Dept of Homoeopathy, Durban Institute of Technology, 2004 xiv, 154 leaves : ill. ; 30 cm / This study was conducted by administering Naja mossambica 30CH (a homoeopathic remedy derived from the venom of the Mozambican spitting cobra) to healthy individuals in order to elicit and document the resulting mental and physical symptomology. These symptoms were compared to the toxicology of Naja mossambica venom as well as a doctrine of signatures analysis of the snake in order to expand and clarify the remedy picture. Existing knowledge of the venom toxicology gives a clear indication of the organs and body systems that the substance has an affinity for. Many poisonous substances used homoeopathically rely heavily on inferences made from the toxicology of the substance, as much of the gross pathology in the symptom picture cannot safely be elucidated in a proving. The aim of this study was to determine the sphere of action of Naja mossambica by utilising symptoms obtained from the proving and from the toxicology of the venom. This was done in order to determine the remedy's usefulness in a homoeopathic clinical setting by expanding our understanding of the substance and thereby facilitating the treatment of disease based on the law of similars.
54

Εισαγωγή και μελέτη μιας νέας κρίσιμης συγκέντρωσης στην περιοχή των αραιών μακρομοριακών διαλυμάτων

Πιερρή, Ευγενία 12 November 2009 (has links)
- / -
55

A homoeopathic drug proving of Carcharhinus leucas 30CH and a subsequent comparison with that of Galeocerdo cuvier hepar 30CH

Naidoo, Nalini January 2018 (has links)
Submitted in partial compliance with the requirements of the Master’s Degree in Technology: Homoeopathy, Durban University of Technology, Durban, South Africa, 2018. / Introduction The aim of this study was to conduct a homoeopathic proving of Carcharhinus leucas in the thirtieth centesimal potency (30CH) and to subsequently establish and describe the symptomatology in standard materia medica format and then compare this symptomatology to Galeocerdo cuvier hepar 30CH. Methodology The homoeopathic proving of Carcharhinus leucas 30CH was conducted at the Durban University of Technology and was accomplished by means of a randomised, double blind, placebo controlled trial. Carcharhinus leucas 30CH was manufactured by the researchers according to Method 6, Method 8a and 10 of the German Homoeopathic Pharmacopoeia (Benyunes, 2005: 36-39). The homoeopathic proving was conducted in the form of a double blind placebo controlled study of Carcharhinus leucas 30CH with a total of 30 healthy provers. The prover sample was divided into two groups by a process of randomisation. Twenty four provers (80%) comprised the verum group and the remaining 6 provers (20%) comprised the placebo group. The identity of the proving substance and the potency used was not disclosed to provers. Provers documented their physical, mental and emotional status for one week preceding the administration of the proving remedy. A comprehensive physical examination and case history of every prover was taken before and after the proving period. Provers were instructed to ingest one powder three times a day for two days but were told to discontinue the powders once symptoms arose. The duration of the proving spanned 6 weeks and throughout the proving process, researchers were in constant communication with all the participants. Upon completion of the proving process, journals were collected and the information therein was translated into materia medica and repertory format. This was done in order to acquire the remedy picture of Carcharhinus leucas 30CH. Thereafter, the symptomatology of Carcharhinus leucas 30CH was compared to the symptomatology of Galeocerdo cuvier hepar 30CH. Results The proving of Carcharhinus leucas 30CH produced a total of 590 already existing rubrics and 43 new rubrics. The majority of these rubrics were located in the MIND (127), GENERALS (64), HEAD (55), EXTREMITIES (50), and EYE (34). In regard to the mind, prominent features were apparent such as anger, anxiety, cheerfulness, an aversion or amelioration within company, difficulty concentrating or increased focus, varying delusions and fears and irritability. Pertaining to the head, headaches were evident with varying concomitants and modalities, with headaches predominantly affecting the forehead and sides. Sensations included dryness, heat, heaviness, perspiration and shaking. The extremities displayed symptoms primarily in the forearms, legs and thighs and sensations included paralysis, shaking, swelling and weakness. In regard to the eye, eye pain with multiple modalities were apparent, with symptoms related to the canthi and eyelids. Sensations included heat, heaviness, inflammation, itching and photophobia as well as a visible discolouration of the eye. Analysis of the results presented an understanding of the similarities and differences between Carcharhinus leucas 30CH and Galeocerdo cuvier hepar 30CH. Conclusion As hypothesised, it was evident that administering Carcharhinus leucas 30CH to healthy individuals did yield observable symptomatology. Additionally, it was apparent that various correlations between Carcharhinus leucas 30CH and Galeocerdo cuvier hepar 30CH existed / M
56

Alterações de propriedades físico-químicas da água tratada com preparados homeopáticos de carbonato de cálcio / Changes in physicochemical properties of water treated with homeopathic preparations of calcium carbonate

Gomes, Lúcia Helena 15 July 2009 (has links)
Made available in DSpace on 2015-03-26T13:39:33Z (GMT). No. of bitstreams: 1 texto completo.pdf: 353643 bytes, checksum: ce546a87aca1ed78224fb60cec1bcce9 (MD5) Previous issue date: 2009-07-15 / The aim of this work was to evaluate the influence of the homeopathic calcium carbonate in the properties of surface water and distilled water, with the purpose of managing the irrigation water and agriculture quality. The experiments were conducted at the Laboratory of Homeopathy, DFT / UFV, where 12 homeopathic solutions were prepared (dynamized in distilled water) and 20 drops of each dynamization process (1 to 12 CH) applied in glass bottles containing 80 mL of mine water (surface water) and distilled water. The experiments were conducted in the factorial scheme 13 x 2 (13 treatments and 2 types of water), and the randomized blocks design was utilized, with 4 replications. The following aspects were determined: Ionic Hydrogen Potential (pH), Electrical Conductivity (EC), Dissolved Oxygen (DO) and Turbidity (TURB) (only in experiment 4) oftreated water. It was concluded that the dynamizations of calcium carbonate caused changes in pH, EC and turbidity of the water. The DO was not affected by the treatment with homeopathic water. Homeopathic preparations xiv caused different responses in relation to the analyzed variables. Changes in mine water and distilled water differ because of the same dynamizations, highlighting the characteristics of each water. / Tendo em vista o manejo da água de irrigação e qualidade da agricultura, objetivou-se avaliar a influência do carbonato de cálcio homeopatizado nas propriedades da água de lençol superficial e da água destilada. Os experimentos foram conduzidos no Laboratório de Homeopatia do DFT/UFV, onde 12 preparados homeopáticos foram elaborados (dinamizados em água destilada) e 20 gotas de cada dinamização (1 a 12CH), aplicadas em frascos de vidro contendo 80 mL de água de mina (lençol superficial) e água destilada. Os experimentos foram instalados no esquema fatorial 13 x 2 (13 tratamentos e 2 tipos de água) e Delineamento de Blocos Casualizados, com 4 repetições. Foram determinados: Potencial Hidrogênio Iônico (pH), Condutividade Elétrica (CE), Oxigênio Dissolvido (OD) e Turbidez (TURB) (somente no experimento 4) da água tratada. Concluiu-se que as dinamizações de Carbonato de cálcio causaram alterações no pH, na CE e na Turbidez da água. O OD não foi influenciado pelo tratamento da água com homeopatia. Os preparados homeopáticos causaram respostas de forma diferenciada em relação às variáveis analisadas. As alterações na água de mina e na água destilada diferiram em função das mesmas dinamizações, evidenciando as características de cada água.
57

Atividade de preparados homeopáticos em água e na temperatura do preparo de altas diluições / Activity of the homeopathic preparations in water and in the preparation of high temperature dilutions

Reis, Iná Lima 27 February 2013 (has links)
Made available in DSpace on 2015-03-26T13:39:57Z (GMT). No. of bitstreams: 1 texto completo.pdf: 336800 bytes, checksum: dcf5acc894daffbac73af611c780a432 (MD5) Previous issue date: 2013-02-27 / Coordenação de Aperfeiçoamento de Pessoal de Nível Superior / The water temperature in agricultural systems influences the development and production of crops, the effect is mostly observed in hydroponic crops where water is the medium in which they are dissolved nutrients for plant development. The mechanisms of action of high dilutions are still unknown. One of the theories associated with the effect of molecular preparations not to water molecules, and the energy present. The biophysical effect of water molecules has not been theorized, however, could prove knowledge of the physical properties of high dilutions to justify their effects. Among them is prominent vibrational energy. The vibration of the water molecule is increased after the process of succussion can be no exchange of energy between the water molecule and the solute molecule. The objective was to evaluate the effect of the six powers prepared high dilution Rhus tox. manipulated on two vehicles (distilled water and 70% ethanol) in water at 40 °C (representing elevated temperature) and evaluating the temperature in steps manipulation high dilution Baptisia tinctoria 3C, Baptisia tinctoria 12C, Atropa belladonna 3C, Atropa belladonna 12C, Hydrophobinum 6C and Hydrophobinum 12C for 72 hours after preparation. In assessing prepared high dilution of Rhus tox. time was observed equilibrium water temperature 40 °C and stabilization of temperature when in contact with water at room temperature (25 °C). There was no significant difference between the effects of high dilution prepared Rhus tox. manipulated with vehicles distilled water and 70% ethanol. There was less time spent in the temperature stabilization the samples treated with the high dilution prepared Rhus tox. 3C, however no significant difference between the effects of preparations Rhus tox. in powers 5C, 7C, 9C and 11C. When evaluating the temperature in steps of preparing high dilutions of various treatments powers were selected with a view to compare the variables in different concentrations of solute. It was observed from the time of preparation until at least 48 hours after which the prepared high dilution the temperature is higher than the vehicle and solution phases. Differences among treatments in which there is dispersed solute and the solute concentration treatments below the inverse Avogadro's number can be compared immediately after sample preparation and after 48 hours. The highest average temperature of cooked high dilution is related to the process of succussion. / A temperatura da água em sistemas agrícolas influencia no desenvolvimento e produção de lavouras, o efeito é observado principalmente em cultivos hidropônicos onde a água é o veículo em que estão dissolvidos os nutrientes necessários ao desenvolvimento das plantas. Os mecanismos de atuação de altas diluições ainda são desconhecidos. Uma das teorias associa o efeito das preparações não moleculares às moléculas de água, e a energia presente. O efeito biofísico das moléculas de água não foi teorizado, entretanto, conhecimentos da física poderiam revelar propriedades das altas diluições que justificassem seus efeitos. Dentre esses conhecimentos é destaque a energia vibratória. O movimento vibratório da molécula de água é aumentado após o processo de sucussão podendo haver permuta de energia entre a molécula da água e a molécula do soluto. O objetivo foi avaliar o efeito de seis potências do preparado de alta diluição Rhus tox. manipulado em dois veículos (água destilada e etanol 70%) em água a 40 °C (representando temperatura elevada) e avaliar a temperatura nas etapas de manipulação dos preparados de alta diluição Baptisia tinctoria 3C, Baptisia tinctoria 12C, Atropa belladona 3C, Atropa belladona 12C, Hydrophobinum 6C e Hydrophobinum 12C por até 72 horas após o preparo. Na avaliação dos preparados de alta diluição de Rhus tox. foi observado o tempo de equilíbrio de temperatura da água à 40 °C, e estabilização da temperatura quando em contato com a água em temperatura ambiente (25 °C). Não houve diferença significativa entre os efeitos dos preparados de alta diluição de Rhus tox. manipulados com os veículos água destilada e etanol 70%. Houve menor tempo gasto na estabilização da temperatura nas amostras tratadas com o preparado de alta diluição Rhus tox. 3C, entretanto não houve diferença significativa entre os efeitos dos preparados de Rhus tox. nas potências 5C, 7C, 9C e 11C. Ao avaliar a temperatura nas etapas de preparo de altas diluições tratamentos de diversas potências foram selecionados com intuito de comparar as variáveis em diversas concentrações do soluto. Foi observado, desde o momento do preparo até no minímo 48 horas após, que no preparado de alta diluição a temperatura é superior em relação as fases veículo e solução. Diferenças entre tratamentos em que há soluto disperso e os tratamentos com concentração de soluto abaixo do inverso do Número de Avogadro podem ser comparadas imediatamente após o preparo das amostras e 48 horas após. A maior média de temperatura dos preparados de alta diluição está relacionada ao processo de sucussão.
58

The effectiveness of homoeopathic simillimum in the treatment of job burnout in the human service field

Vaithilingam, Heshma January 2005 (has links)
Thesis(M.Tech.: Homoeopathy)-Dept of Homoeopathy, Durban Institute of Technology, 2005 xxiii, 96 leaves / The purpose of this double blind placebo controlled study was to evaluate the efficacy of homoeopathic simillimum in the treatment of job burnout in the human services field. / M
59

A Homoeopathic C4 trituration proving of Withania somnifera with a subsequent comparison to the conventional 30CH proving of Withania somnifera

Pillay, Nickita Nikki January 2017 (has links)
Submitted in partial compliance with the requirements of the Master’s Degree in Technology: Homoeopathy, Durban University of Technology, Durban, South Africa, 2017. / The C4 trituration method is a unique method for homoeopathically proving a substance and determining its therapeutic properties. The process requires the use of a mortar and pestle and involves many rounds of grinding (triturating) the raw substance. During the trituration process symptoms are experienced by the triturator. Withania somnifera, commonly known as Ashwagandha in Ayurvedic medicine is highly regarded for its clinical efficacy as an adaptogenic herb. Due to the herb’s therapeutic properties and extensive use in Ayurvedic medicine a comprehensive homoeopathic drug proving was conducted at The Durban University of Technology by Laidlaw in 2015. Aim The aim of this study was to conduct a homoeopathic C4 trituration proving of Withania somnifera with a subsequent comparison to the conventional 30CH proving of Withania somnifera which was conducted by Laidlaw in 2015. The study was of a qualitative and exploratory nature hence employed a qualitative methodology with purposive sampling. Participants were required to triturate up to the fourth potency [C4] and all the symptoms experienced were recorded in the journals provided. The study incorporated thematic analyses of data. The data was transliterated by the researcher, thereafter those symptoms were classified systematically and converted into rubrics using Schroyens (2012) repertory. Recorded symptoms were collated to create a C4 trituration representation. Subsequently the symptoms obtained from the C4 trituration proving of Withania somnifera was comparatively analysed against the symptoms of the conventional 30CH proving of Withania somnifera, which was conducted by Laidlaw (2015). Method This research study followed a qualitative methodology which comprised a single blind study, and a proving sample. This was a qualitative study; the requirement for sample size is usually up to 10 participants until saturation of data, but this study utilised 18 participants to ensure the generation of rich data. Participants triturated 91: 100 lactose to the fourth potency [C4] using a mortar and pestle. All symptoms experienced were recorded in journals. The analysis of the data followed a qualitative phenomenological methodology. Results The C4 trituration proving yielded 145 rubrics. Two of these rubrics were newly formulated. The majority of the rubrics were produced in the MIND and HEAD section. There were 100 Grade 1 rubrics, 44 Grade 2 rubrics and 1 Grade 3 rubrics. Conlcusion The C4 trituration produced a symptom picture of Withania somnifera, which was comparable to the 30CH conventional proving. The C4 trituration proving produced observable changes in the triturators’ state of health but predominantly MIND symptoms were evoked. The symptom picture created with the C4 trituration had many similarities to the 30CH conventional proving. The polarity of symptoms that existed in Withania somnifera was observed in both provings and included symptoms such as: anxiety vs tranquillity, increased concentration vs decrease in concentration. Differences between the C4 trituration proving and the 30CH conventional proving were found in the description of physical symptoms such as headaches, in the types of delusions that occurred in each proving, and in some mental symptoms such as anger, sadness, clarity, and introspection. / M
60

Comparative nuclear magnetic resonance study of Natrum muriaticum LM1 produced in-house and obtained from commercial sources respectively

Miller, Garth Meredith January 2017 (has links)
Submitted in partial compliance with the requirements of the Master’s Degree in Technology: Homoeopathy, Durban University of Technology, Durban, South Africa, 2017. / Introduction Hahnemann was adamant that his methodology for LM1 prescription be reproduced exactly, in order to develop the latent medicinal properties of the crude substance reliably (Barthel 1991). Yet quality assurance practices during manufacturing are currently aligned to Good Manufacturing Process, in adherence to Pharmacopeia which permit substantial deviation from the strict quantities and practices (Kayne 2006) prescribed in Hahnemann’s 6th edition Organon (Hahnemann and O'Reilly 2001). Often the equipment, methods and practices favour expedience or utilise new technologies, under an assumption that the remedy produced is unaffected, since the mechanisms underlying the action of homoeopathic remedies are not understood or determined (Barthel 1991). Aim The primary purpose of this study was to compare and evaluate the nuclear magnetic resonance (NMR) spectra of Natrum muriaticum LM1, produced using strict adherence to original Hahnemannian methodology, to samples sourced from a representative variety of sources available to local homoeopathic practitioners, in the medicinal prescription form patients may receive. Additionally, the researcher set out to confirm that these Natrum muriaticum LM1 samples could be shown to produce distinct NMR spectra when compared to a Lactose LM1 control. The final objective was to ascertain whether two samples produced with the same strict adherence to Hahnemannian methodology, from same source materials would yield similar NMR Spectra, distinct from a Lactose LM1 control sample. Methodology The researcher produced an in-house Natrum muriaticum LM1 (0/1) sample in accordance with aphorism 272 of the 6th edition Organon (Hahnemann and O'Reilly 2001). Similarly, a second sample was produced by the DUT Homoeopharmaceutics Senior Lecturer, within the same ambient conditions and protocol. A third sample was produced by a local make-to-order (MTO) company, using the same sodium chloride crude substance sample utilised in the production of the first two samples. These three samples emulate the make-to-order (MTO) options available to homoeopathic practitioners. A fourth sample was obtained ex-stock from highly regarded local supplier (Homoeopathix Trading Company (South Africa)), while the fifth and sixth samples were procured ex-stock from highly regarded suppliers abroad, Helios (United Kingdom) and Roy & Co. (India) respectively. These samples represented the make-to-stock (MTS) sourcing options available to homoeopathic community. The researcher transported the samples to Chemistry Department of the University of Stellenbosch Chemistry Department in Cape Town. Any external influences such as vibration, changes in temperature, electromagnetic disturbances, heat or strong light were avoided or minimised as far as was practical. The six LM1 potency samples were prepared immediately prior to NMR analysis from their respective source materials to a 20% alcohol concentration, as could be done in practice for the patient prescription where the alcohol content would serve as a preservative. Four controls comprised the seventh, eighth, ninth and tenth samples, for comparative analysis and to confirm sample homogeneity. . Lactose (LM1) . Source lactose in solution . Water used in preparation of NMR samples . Ethanol solvent The ten samples were assigned a random reference number by Dr Jaco Brand (Nuclear Magnetic Resonance Unit Manager), to remove bias during NMR analysis. Five samples were drawn from each of the ten randomised samples and labelled, while deuterated dimethyl sulfoxide-d6 (DSMO) contained within a separate capillary tube served as an external lock and reference solvent. The researcher then carried out the analysis under qualified supervision to ensure best-practice was applied throughout. The resulting data (FID) was processed to derive the chemical shift and relative integration values, which were captured into a Microsoft® Excel 2010 spreadsheet to calculate the relative integration values of each sample run. Statistical analysis was performed in GNU PSPP version 085, the data was analysed using descriptive statistics and the non-parametric tests, Kruskal-Wallis and Mann-Whitney U-test (due to small data size and nature of distribution) at a statistical significance interval of α = 0.05. Results Natrum muriaticum LM1 samples sourced from a variety of make-to-order (MTO) and make-to-stock manufacturing environments produced almost universally distinct NMR spectra profiles in terms of chemical shifts and relative integration values of the CH2, CH3 and H2O signals, at an alcohol concentration of 20%, when compared to a Lactose LM1 control sample. When the NMR spectra of make-to-order (MTO) and make-to-stock (MTS) remedies were analysed and compared to each other in terms of chemical shifts and relative integration values of the CH2, CH3 and H2O signals, they were for the most part statistically distinct, but some anomalous results emerged. There was no statically significant difference in NMR spectra in terms of chemical shift, between the two samples produced in the same environment using the methodology to closely aligned to Organon (Hahnemann and O'Reilly 2001), yet in terms of relative integration values, they were statistically distinct. Conclusion The low alcohol percentage associated with the medicinal dosage of LM1 prepared for analysis failed to produce an OH peak on NMR spectra. In addition, it is not possible to identify the variables or indeed account for the nature of NMR spectra that are produced after sample analysis. This study concludes that while NMR was able to discern physico-chemical distinction between LM1 potency Natrum muriaticum remedies to control conclusively, this does not translate to practical application of NMR for quality control or remedy comparison for LM potencies at alcohol content levels, associated with medicinal prescription. / M

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