Freie Univ., Diss.--Berlin, 2000.

Univ., Diss.--Marburg, 2000.

Univ., Diss.-2001--Köln, 2000. / Literaturverz. S. [250] - 261.

Univ., Diss.--Saarbrücken, 2002.

Loose Id, scored for orchestra (piccolo, 2 flutes, 2 oboes, 2 clarinets in B-flat, B-flat contrabass clarinet, 2 bassoons, contrabassoon, 4 horns in F, 3 trumpets in B-flat, 2 trombones, 1 bass trombone, tuba, timpani, percussion (3 parts), violin I, violin II, viola, violoncello, and contrabass), is an abstract realization in sound of the energy of the Id. Unleashed, without the counterbalance of Ego or Superego, the Id generates unbridled instinctual energy, resulting in an orgiastic frenzy. Distinct from a state of dementia, this piece represents a thoroughly lucid and intentional rampage of self-indulgence. The accompanying essay examines the underlying structural principles of Loose Id, focusing on how they aid the creation of the overall experience of the piece. Particular attention is given to the concepts of linearity and nonlinearity and their roles in different levels of creative and listening processes.

Zugl.: Augsburg, Univ., Diss., 2009

Zugl.: Münster (Westfalen), Univ., Diss., 2008

The work was concerned with experimental study of the turbulent flame development process of alcohol fuels, namely ethanol and butanol, in an optically accessed spark ignition research engine. The fuels were evaluated in a single cylinder engine equipped with full-bore overhead optical access operated at typical stoichiometric part-load conditions with images captured using high-speed natural light imaging techniques (or chemiluminescence). The differences in flame development between the fuels was analysed to understand better the impact of high and low alcohol content fuels on combustion. Advanced image analysis, in conjunction with Ricardo WAVE simulation, allowed for the conclusion that the faster burning exhibited by ethanol was the result of the marginally higher laminar burning velocity providing a faster laminar burn phase and accelerating the flame into the turbulent spectrum thus reducing bulk flame distortion and better in-cylinder pressure development. Such physical reactions are often over-looked in the face of chemical differences between fuels. A further study into the variation of maximum in-cylinder pressure values was conducted focussing on iso-octane and ethanol. This study identified two phenomena, namely “saw-toothing” and “creep” in which cluster of cycles feed into one another. From this it became clear that the presence of high pressure during the exhaust process had a large influence on the following cycles. This is another often overlooked phenomenon of direct cycle-to-cycle variation whereby incylinder pressures during blowdown can dictate the duration, load or stability output of the following cycle. Finally the work investigated the impact on flame development of alcohol fuels when the overlap duration was altered. While the engine produced counterintuitive figures of residual gas, ethanol was confirmed as having greater synergy with EGR by displaying less impacted combustion durations c.f. iso-octane. Care should be taken however when analysing these results due to the unique valve configuration of the engine.

Regeringen beslutade den 21 december 2015 att införa tillfälliga ID-kontroller vid landets gränser. Detta på grund av att den dåvarande flyktingkrisen enligt regeringen innebar en allvarlig fara för allmän ordning och säkerhet. Denna uppsats analyserar den proposition, riksdagsdebatt samt följdmotioner som låg till grund för lagen genom en idealtypsanalys. En hel del kritik uppkom i samband med lagen, dels på grund av bristfällig beredning, dels på grund av dess påverkan på asylrätten. Studien undersöker hur riksdagspartierna förhåller sig till asylrätten i relation till den motsättning som kan urskiljas mellan nationell suveränitet och deklarationer om mänskliga rättigheter. Resultatet visar att de flesta riksdagspartier anser att asylrätten principiellt är viktig men att nationens intressen kommer i första hand. Centerpartiet och Vänsterpartiet värnar istället i första hand asylrätten, vilken de ser som en absolut rätt.

Philosophiae Doctor - PhD / Sequencing an HIV quasispecies with next generation sequencing technologies yields a dataset with significant amplification bias and errors resulting from both the PCR and sequencing steps. Both the amplification bias and sequencing error can be reduced by labelling each cDNA (generated during the reverse transcription of the viral RNA to DNA prior to PCR) with a random sequence tag called a Primer ID (PID). Processing PID data requires additional computational steps, presenting a barrier to the uptake of this method. MotifBinner is an R package designed to handle PID data with a focus on resolving potential problems in the dataset. MotifBinner groups sequences into bins by their PID tags, identifies and removes false unique bins, produced from sequencing errors in the PID tags, as well as removing outlier sequences from within a bin. MotifBinner produces a consensus sequence for each bin, as well as a detailed report for the dataset, detailing the number of sequences per bin, the number of outlying sequences per bin, rates of chimerism, the number of degenerate letters in the final consensus sequences and the most divergent consensus sequences (potential contaminants). We characterized the ability of the PID approach to reduce the effect of sequencing error, to detect minority variants in viral quasispecies and to reduce the rates of PCR induced recombination. We produced reference samples with known variants at known frequencies to study the effectiveness of increasing PCR elongation time, decreasing the number of PCR cycles, and sample partitioning, by means of dPCR (droplet PCR), on PCR induced recombination. After sequencing these artificial samples with the PID approach, each consensus sequence was compared to the known variants. There are complex relationships between the sample preparation protocol and the characteristics of the resulting dataset. We produce a set of recommendations that can be used to inform sample preparation that is the most useful the particular study. The AMP trial infuses HIV-negative patients with the VRC01 antibody and monitors for HIV infections. Accurately timing the infection event and reconstructing the founder viruses of these infections are critical for relating infection risk to antibody titer and homology between the founder virus and antibody binding sites. Dr. Paul Edlefsen at the Fred Hutch Cancer Research Institute developed a pipeline that performs infection timing and founder reconstruction. Here, we document a portion of the pipeline, produce detailed tests for that portion of the pipeline and investigate the robustness of some of the tools used in the pipeline to violations of their assumptions.