<p>Uvod. Rak debelog creva predstavlja 9,7% svih malignih bolesti u svetu, i drugi ili treći je po učestalosti u onkolo&scaron;koj strukturi obolevanja, u zavisnosti od pola. Skrining, ili sekundarna prevencija populacije u prosečnom riziku ima centralnu ulogu u kontroli kolorektalnog karcinoma. Cilj. Utvrditi nivo znanja, stavove i pona&scaron;anje u odnosu na rak debelog creva i njihov uticaj na odaziv na skrining raka debelog creva, u zavisnosti od primenjenog modela skrininga. Materijal i metode. U istraživanje je pozvano 1.213 osoba oba pola, starosti 50-74 godine, za uče&scaron;će u studiji znanja, stavova i pona&scaron;anja (KAP studija) u odnosu na rak debelog creva, popunjavanjem upitnika (Sessa A). Formirane su tri grupe prema modelu skrininga: populacioni - model 0; oportuni skrining uz kontakt ispitanika sa medicinskim osobljem, bez dodatnih informacija o bolesti, skriningu i testu &ndash; model 1; oportuni skrining kada se uz kontakt sa medicinskim osobljem dobija informacija o bolesti i skriningu, uz prikaz izvođenja testa - model 2. U ovoj studiji je kao skrining metoda kori&scaron;ćen imunolo&scaron;ki test stolice -Wondfo FOB.Obrada podataka je rađena statističkim programom SPSS (version 13). Značajnost razlika je testirana parametrijskim (t-test, ANOVA) i neparametrijskim (Mann-Whitney U test) testovima, dok se komparacija kategoričkih varijabli vr&scaron;ila &chi;&sup2; testom i Fisher Exact testom. Test-retest analiza je rađena Cohen&#39;s Kappa testom. Rezultati. Od 1.213 pozvanih, 666 (55%) osoba je prihvatilo uče&scaron;će u KAP studiji. Vi&scaron;e od polovine (54,5%) ispitanika ima ukupan skor znanja manji od 50%. Nivo znanja, sociodemografske karakteristike, procena sopstvenog rizika obolevanja, stav u odnosu na korist testa, stepen sopstvenog rizika obolevanja i mogućnosti prevencije raka debelog creva, nisu faktori koji utiči na participaciju u skriningu kolorektalnog karcinoma. Najvažniji faktor za uče&scaron;će u skriningu u ovom istraživanju je kontakt i razgovor sa lekarom o bolesti, prevenciji i skrining testu.Odaziv u skrining, u odnosu na celokupno pozvanu populaciju je 51,2%. Od ispitanika koji su popunili anketni upitnik, participacija u skriningu je 93,4%. Statistički značajno manji odaziv u skriningu je u modelu 0 (12%) i modelu 1 (6%) u odnosu na model 2 (1%). Zaključak. Poznavanje bolesti, faktora rizika i mogućnosti prevencije generalno je oskudno, ali ne utiče na participaciju u skriningu. Faktor koji utiče na visok odaziv u skrining kolorektalnog karcinoma je kontakt i razgovor sa medicinskim osobljem, pre svega sa lekarom.</p> / <p>Introduction. Colorectal cancer represents 9.7% of all malignancies in the world and it is second or third in frequency in oncological structure depending on the sex. Screening, or secondary prevention of the average risk in the population has a central role in the control of colorectal cancer. Aim. Determine the level of knowledge, attitudes and behaviour in relation to colon cancer and their impact on turnout for colorectal cancer screening, depending on the applied screening model. Material and method. There were 1213 people of both sexes aged 50-74 years participating in this study of knowledge, attitudes and practice (KAP studies) in relation to colorectal cancer, by filling in the questionnaire (Sessa A). Three groups were formed with respect to model screening: population - model 0; opportunistic screening involving the contact of patients and medical staff, without receiving additional information about the disease, screening and test - model 1; opportunistic screening involving the contact of patients and medical staff while receiving information about the disease and screening, and explaining the test performance - model 2. In this study, a screening method used was fecal occult blood test - Wondfo FOB. Data processing is performed by the statistical program SPSS (version 13). The significance of differences was tested by parametric (t-test, ANOVA) and nonparametric (Mann-Whitney U test) tests, while the comparison of categorical variables was performed with &chi;&sup2; test and Fisher Exact test. Test-retest analysis was performed with Cohen&rsquo;s Kappa test. Results. Out of all the 1213 participants, 666 (55%) of them accepted to participate in the KAP study. More than half of them (54.5%) have a total score of knowledge less than 50%. The level of knowledge, socio-demographic characteristics, assessment of the risk of the disease, the attitude towards the benefit of the test, degree of the risk of disease and opportunities for prevention of colorectal cancer, are not factors in deciding to participate in the screening of colorectal cancer. The most important factor for the participation in the screening in this study is the contact and conversation with the doctor about the disease, prevention and screening test. The turnout for the screening, in relation to the number of people who participated is 51.2%. Out of those who completed the questionnaire, participation in the screening is 93.4 %. Statistically significantly lower response in the screening is in model 0 (12%) and in model 1 (6%) in relation to model 2 (1%). Conclusion. Knowledge of the disease, risk factors and prevention opportunities are generally scarce, but do not affect the participation in screening. The factor influencing the high turnout for colorectal cancer screening is contact and conversation with the medical staff, primarily the doctor.</p>

Made available in DSpace on 2016-04-27T18:47:21Z (GMT). No. of bitstreams: 1 GER - Lucia Teixeira Lopes Ferraz.pdf: 467462 bytes, checksum: 9ddea662708bc1faaa404dcdd0a6ffbc (MD5) Previous issue date: 2006-10-02 / The early detection and prevention of breast cancer in middle age and elderly age women, through the analysis of their bodily symptoms, is the main purpose of this article. The world is undergoing a transformation both in its demography and in its epidemiology. Demographically, the aging of our population is a direct consequence of the increase of the life expectancy. Thought observed in both sexes, this increase is greater for women. Epidemiologically, these changes in demographics have caused a change in the cause of death profile of the population. One of the representations of these changes is the fall in the death-rate of infect-contagious diseases, characteristic of younger populations, and a rise in the death-rate of chronicle diseases, which are characteristic of populations with a predominance of older people. In Brazil, cancer is one of the main causes of death among the elderly, being breast cancer one of the main female causes of death. The public health policy is geared mainly towards the early detection of this disease, being the clinical mammography and ultra-sound exams the main methods used. However, these diseases are usually diagnosed too late, frequently leading to deaths. For the purposes of this research, a qualitative approach was adopted. The chosen subjects were middle age and elderly women who were frequent patients at Jardim Colorado s basic health unit, in Suzano, São Paulo. The chosen procedure was an interview with each subject in separate. The main focus of the interview was to get to know which signs these women looked for in their bodies and which procedures they adopted to diagnosis breast cancer on themselves. Through this series of interviews, it was discovered that the mere transmission of information regarding the prevention of breast cancer is not enough to ensure that the recommended procedures are followed. This implies that health campaigns by themselves are not as effective if not accompanied by procedures that ensure both that these women incorporate and use the knowledge acquired as well as that they routinely visit health units in order to undergo the necessary exams. It was thus concluded that, in the specific subject of early cancer detection in middle age and elderly women, it s mandatory that public policies focus in creating in younger women a culture in which it s common for people to frequently visit public health systems to be examined / A investigação das representações do corpo em mulheres envelhescentes e idosas, através dos procedimentos adotados para a prevenção e detecção precoce do câncer de mama, é o objetivo central dessa dissertação. O mundo está passando por uma dupla transição - demográfica e epidemiológica. Demograficamente, o envelhecimento populacional resulta do aumento da esperança de vida ao nascer; apesar de observado em ambos os sexos, este aumento é mais acentuada nas mulheres ( feminização da velhice). Epidemiologicamente, a transição demográfica levou à alteração do perfil de morbimortalidade da população, diminuindo a prevalência das doenças infectocontagiosas, que afetam principalmente os jovens, e aumentando a prevalência das doenças crônicas, típicas de pessoas mais idosas. No Brasil, o câncer situa - se entre as doenças crônicas que mais acometem a população encontra-se; nas mulheres o de mama constitui uma das principais causas de morte. As ações de saúde pública para o diagnóstico do câncer de mama são direcionadas para sua detecção precoce; esta ocorre, principalmente, através do rastreamento de mulheres pelo exame clínico da mama, pela mamografia e pela ultrassonografia da mama. No entanto, os diagnósticos são feitos tardiamente, levando muitas vezes ao óbito. Em termos metodológicos, optou-se pela abordagem qualitativa; os sujeitos foram mulheres envelhescentes ou idosas que freqüentavam a Unidade Básica de Saúde do Jardim Colorado, em Suzano, São Paulo. O procedimento adotado para a coleta de dados foi a entrevista individual em profundidade. Com ela procuramos conhecer as representações de corpo a partir da investigação dos procedimentos adotados para a prevenção do câncer de mama. Na análise das entrevistas compreendemos que não basta a transmissão de informações sobre a prevenção para que sua prática seja efetiva, ou seja, que é necessário que as campanhas sejam acompanhadas de mecanismos que garantam a freqüência das mulheres aos serviços de saúde e a incorporação dos conhecimentos sobre corpo, saúde, envelhecimento. Concluímos que no caso específico da detecção precoce do câncer de mama em mulheres envelhescentes e idosas deve-se iniciar a formação de um conhecimento específico que objetiva a criação de um vínculo com os serviços de saúde, através do diálogo e da reflexão, desde a adolescência, para que seja disseminado em todas as etapas seguintes da vida da mulher. Para isto, as políticas públicas devem prever e contemplar essas ações de saúde

By 2020, cancer mortality rates are estimated to increase by 180% in Arab countries, where breast cancer is the most common type of cancer. This thesis explores and evaluates the ‘asabiyya-driven structuration (the cohesive force of the group that gives it strength in facing its struggles for progressive reproduction) of cancer agents, government agents, and the World Health Organization agents for breast cancer prevention and early detection in the Arab region. The layers of the philosophical standing from Ibn Khaldûn’s concept of ‘asabiyya and the theoretical foundation of social systems theory, structuration theory, social network analysis, and social capital theory are peeled in order to explore and evaluate the context, constraints, social networks, autopoiesis, and social capital. Utilizing a qualitative research design, this thesis employs content analysis and in-depth interviews, as well as NVivo as a tool for analysis. Data is collected from 122 publications and knowledgeable informants employed by cancer agencies, ministries of health, and World Health Organization offices in Egypt, Jordan, Morocco, and Oman. The findings are divided into the contextual scope of responsibility and resources, the progressive and hierarchal constraining structure, the optimal and weak social networks, the strong and vulnerable shields of autopoiesis, and the presence and absence of social capital momentum, followed by a discussion on the the struggle for structuration against breast cancer. The findings demonstrate that countries with a national cancer control program witness local strengthening ‘asabiyya and ‘asabiyya-driven structuration, while those without a national cancer control program witness weakening local ‘asabiyya. Ultimately, this thesis proposes strategic recommendations to accelerate the regional ‘asabiyya-driven structuration of breast cancer.

By 2020, cancer mortality rates are estimated to increase by 180% in Arab countries, where breast cancer is the most common type of cancer. This thesis explores and evaluates the ‘asabiyya-driven structuration (the cohesive force of the group that gives it strength in facing its struggles for progressive reproduction) of cancer agents, government agents, and the World Health Organization agents for breast cancer prevention and early detection in the Arab region. The layers of the philosophical standing from Ibn Khaldûn’s concept of ‘asabiyya and the theoretical foundation of social systems theory, structuration theory, social network analysis, and social capital theory are peeled in order to explore and evaluate the context, constraints, social networks, autopoiesis, and social capital. Utilizing a qualitative research design, this thesis employs content analysis and in-depth interviews, as well as NVivo as a tool for analysis. Data is collected from 122 publications and knowledgeable informants employed by cancer agencies, ministries of health, and World Health Organization offices in Egypt, Jordan, Morocco, and Oman. The findings are divided into the contextual scope of responsibility and resources, the progressive and hierarchal constraining structure, the optimal and weak social networks, the strong and vulnerable shields of autopoiesis, and the presence and absence of social capital momentum, followed by a discussion on the the struggle for structuration against breast cancer. The findings demonstrate that countries with a national cancer control program witness local strengthening ‘asabiyya and ‘asabiyya-driven structuration, while those without a national cancer control program witness weakening local ‘asabiyya. Ultimately, this thesis proposes strategic recommendations to accelerate the regional ‘asabiyya-driven structuration of breast cancer.

The aim of this thesis was to describe inequalities in the use of different health care services according to socioeconomic position (SEP) in Catalonia, Spain and Europe. In addition, we intended to assess whether the public coverage of the services, in particular dental health care, has an influence on the magnitude of inequalities in the use of such services. Finally, we aimed to determine the influence of population-based female cancer screening programmes on the prevalence of screening and on the extent of inequality. To accomplish these objectives four studies were carried out. The sources of information of the four studies were, respectively: several editions of the Catalan Health general practitioner (GP) services are equitable or manual classes use them to a greater extent. However, there are marked SEP inequalities in the use of outpatient specialist services, especially in dental care. Socioeconomic inequalities in use of dental care services exist throughout Europe, but they are larger in countries in which dental care is not covered at all by the public health care system than in countries in which dental care is partially covered. In Europe, socioeconomic inequalities in breast and cervical cancer screening are not found in countries with population-based screening programmes but they are found in those countries with only regional or pilot programmes and in those countries with opportunistic screening. / L'objectiu d'aquesta tesi era descriure les desigualtats en l'ús de diferents serveis sanitaris segons la posició socioeconòmica a Catalunya, Espanya i a Europa. A més a més, es volia avaluar si la cobertura pública dels serveis, en particular la dels serveis dentals, infuencia la magnitud de les desigualtats socioeconòmiques en l'ús d'aquests serveis. Finalment, es va voler determinar la influència dels programes poblacionals de cribratge dels càncers de mama i cèrvix en la prevalença de cribratge i en la magnitud de les desigualtats. Per tal d'assolir aquests objectius es van dur a terme 4 estudis. Les fonts d'informació d'aquests estudis van ser, respectivament: diferents edicions de l'Enquesta de Salut de Catalunya (ESCA), diferents edicions de l'Enquesta Nacional de Salut d'Espanya (ENS), l'Enquesta de Salut, Envelliment i Jubilació a Europa (SHARE) 2006 i dades dels països europeus que van participar a l'Enquesta Mundial de la Salut de l'OMS l'any 2002. Els dos primers estudis eren estudis de tendències mentre que els dos últims van ser transversals. En tots els estudis les desigualtats socioeconòmiques es van mesurar mitjançant índexos relatius (RII) i absoluts (SII) de desigualtat. Els resultats d'aquests estudis mostren que a Catalunya i a Espanya els serveis d'atenció primària són equitatius o fins i tot les persones de classes manuals en presenten una major proporció d'ús. Tanmateix, hi ha marcades desigualtats en visites a l'especialista, en especial en les visites al dentista. Les desigualtats socioeconòmiques en la utilització dels serveis dentals existeixen a tota Europa, però són més grans en aquells països on l'atenció dental no està coberta pel sistema públic de salut que en aquells països on aquesta està parcialment coberta. A Europa, no es troben desigualtats socioeconòmiques en el cribratge dels càncers de mama i cèrvix en aquells països amb programes poblacionals de cribratge, però sí que es troben en aquells països amb programes pilot o regionals o amb només cribratge oportunista.

By 2020, cancer mortality rates are estimated to increase by 180% in Arab countries, where breast cancer is the most common type of cancer. This thesis explores and evaluates the ‘asabiyya-driven structuration (the cohesive force of the group that gives it strength in facing its struggles for progressive reproduction) of cancer agents, government agents, and the World Health Organization agents for breast cancer prevention and early detection in the Arab region. The layers of the philosophical standing from Ibn Khaldûn’s concept of ‘asabiyya and the theoretical foundation of social systems theory, structuration theory, social network analysis, and social capital theory are peeled in order to explore and evaluate the context, constraints, social networks, autopoiesis, and social capital. Utilizing a qualitative research design, this thesis employs content analysis and in-depth interviews, as well as NVivo as a tool for analysis. Data is collected from 122 publications and knowledgeable informants employed by cancer agencies, ministries of health, and World Health Organization offices in Egypt, Jordan, Morocco, and Oman. The findings are divided into the contextual scope of responsibility and resources, the progressive and hierarchal constraining structure, the optimal and weak social networks, the strong and vulnerable shields of autopoiesis, and the presence and absence of social capital momentum, followed by a discussion on the the struggle for structuration against breast cancer. The findings demonstrate that countries with a national cancer control program witness local strengthening ‘asabiyya and ‘asabiyya-driven structuration, while those without a national cancer control program witness weakening local ‘asabiyya. Ultimately, this thesis proposes strategic recommendations to accelerate the regional ‘asabiyya-driven structuration of breast cancer.

Made available in DSpace on 2016-03-15T19:40:52Z (GMT). No. of bitstreams: 1 Jael Breitschwerdt.pdf: 952030 bytes, checksum: 787f5cd0ef86094489b72b510635ffc9 (MD5) Previous issue date: 2010-06-08 / Fundo Mackenzie de Pesquisa / The aim of this study was to evaluate early signs of Autism Spectrum Disorders, using retrospective video analysis. The participants were eight children later diagnosed with ASD and eight children with typical development. Home videos of the participants were collected from families, at the ages 12, 24 and 36 months. Videos were edited and then analysed by two ASD specialists. The behaviors: Eye Contact; Facial Expression; Play behavior/ Imitation; Communication; Joint Attention and Repetitive Behaviors, were analysed. The results suggest that early signs such as, deficits in Communication, Play behavior, Imitation and Repetitive behaviors, can be detected in infants at 24 months. Most importantly, findings indicate that deficit in Joint Attention was the most discriminating sign of children with ASD, as early as 12 months. / O objetivo desta pesquisa foi avaliar sinais precoces dos Transtornos do Espectro Autista, por meio da observação de vídeos. Os participantes foram oito crianças diagnosticadas com TEA e oito crianças com desenvolvimento típico, nas idades 12, 24 e 36 meses. Os comportamentos: Contato Visual; Expressão Facial/Sorriso Social; Brincadeiras/Imitação; Comunicação; Atenção Compartilhada; Comportamentos Estereotipados, foram analisados e classificados por dois especialistas. Os resultados sugerem que sinais como disfunções na Brincadeira/Imitação, Comunicação e Comportamentos Estereotipados podem ser detectados a partir de 24 meses de idade. Déficits na Atenção Compartilhada foi o sinal que mais discriminou as crianças com TEA das crianças com desenvolvimento típico, já aos 12 meses de idade.

By 2020, cancer mortality rates are estimated to increase by 180% in Arab countries, where breast cancer is the most common type of cancer. This thesis explores and evaluates the ‘asabiyya-driven structuration (the cohesive force of the group that gives it strength in facing its struggles for progressive reproduction) of cancer agents, government agents, and the World Health Organization agents for breast cancer prevention and early detection in the Arab region. The layers of the philosophical standing from Ibn Khaldûn’s concept of ‘asabiyya and the theoretical foundation of social systems theory, structuration theory, social network analysis, and social capital theory are peeled in order to explore and evaluate the context, constraints, social networks, autopoiesis, and social capital. Utilizing a qualitative research design, this thesis employs content analysis and in-depth interviews, as well as NVivo as a tool for analysis. Data is collected from 122 publications and knowledgeable informants employed by cancer agencies, ministries of health, and World Health Organization offices in Egypt, Jordan, Morocco, and Oman. The findings are divided into the contextual scope of responsibility and resources, the progressive and hierarchal constraining structure, the optimal and weak social networks, the strong and vulnerable shields of autopoiesis, and the presence and absence of social capital momentum, followed by a discussion on the the struggle for structuration against breast cancer. The findings demonstrate that countries with a national cancer control program witness local strengthening ‘asabiyya and ‘asabiyya-driven structuration, while those without a national cancer control program witness weakening local ‘asabiyya. Ultimately, this thesis proposes strategic recommendations to accelerate the regional ‘asabiyya-driven structuration of breast cancer.

Sammanfattning: Introduktion: Tidig upptäckt av cerebral pares (CP) möjliggör tidig behandling, när hjärnans plasticitet är bäst, vilket optimerar barnets utveckling. I Sverige erbjuds alla barn motoriska utvecklingsuppföljningar inom barnhälsovården (BHV). Barn med kända riskfaktorer för CP följs dessutom inom neonatala uppföljningsprogram, där evidensbaserade bedömningsmetoder används vid motorisk bedömning. För en patientsäker vård behöver nedsatt motorik och CP tidigt identifieras, oberoende vart barnen följs. Syfte: Undersöka skillnader mellan barn med CP tillhörande högriskgrupp (HR) eller lågriskgrupp (LR), gällande första kontakt med fysioterapeut och motorisk bedömning, i Region Uppsala. Metod: Kvantitativ journalstudie med deskriptiv, retrospektiv och komparativ design valdes. Barn födda 2010-2016, diagnostiserade med CP 2010-2018 i Region Uppsala inkluderades. Barnen delades in i HR/LR för CP. Mätvariabler: motorisk nivå och kvalitet, funktionsnivå, typ av CP, ålder första kontakt med fysioterapeut samt ålder remittering till habiliteringsverksamheten. Deskriptiv statistik och icke-parametriska statistiska test användes, p-värde ≤0.05. Resultat: Trettiosju barn inkluderades, 22 HR/15 LR för CP. Barnen med högrisk bedömdes av fysioterapeut, erbjöds behandling samt remitterades till habiliteringsverksamheten signifikant tidigare. Barn med sämre funktionsnivå remitterades signifikant tidigare till habiliteringsverksamheten. Slutsats: Barn med CP i Region Uppsala har ojämlik tillgång till fysioterapeutiska bedömningar och behandlingar. Barn med högrisk för CP bedömdes av fysioterapeut och remitterades till habiliteringsverksamheten tidigare.  Barn med sämre funktionsnivå remitterades också tidigare. Evidensbaserade bedömningsmetoder verkar möjliggöra tidig upptäckt av motoriska avvikelser och därigenom möjlighet till tidiga interventioner. Ett sätt att erbjuda patientsäker och jämlik vård för barn med utvecklingsavvikelser, kan vara att använda evidensbaserade bedömningametoder inom verksamheter vars mål är identifiering av utvecklingsavvikelser. / Abstract: Introduction: Early detection of cerebral palsy (CP) allows for early treatment, when brain plasticity is at its best, which optimizes the child's development. In Sweden, all children are offered motor developmental surveillance in child health services. In addition children with known riskfactors of developing CP are enrolled in neonatal follow-up, using evidence-based assessment methods. In order to provide patientsafe and quality of care, early identification of impaired motor function and CP is needed, regardless of where the children are monitored. Aims: Investigate differences between children belonging to high or low riskgroup for CP regarding first contact with physiotherapist and assessed motorskills, in Region Uppsala. Methods: A quantitative journalstudy with descriptive, retrospective and comparative design was selected. Children born 2010-2016 diagnosed with CP 2010-2018 in Region Uppsala were included and divided into children with high or low risk to develop CP. Measures: motor performance, level of disability, type of CP, first visit at physiotherapist, age of reffered to habilitation-services. Descriptive statistics and non-parametric statistical tests were used, p-value ≤0.05. Results: Thirty-seven children were included, 22 with high-risk and 15 with low-risk for CP. Children with high-risk were assessed by physioterapist and referred to habilitation-services significantly earlier. Children with more severe disability were also referred significantly earlier. Conclusion: Children with CP in Region Uppsala have unequal access to timely physiotherapy and habilitation-services. Evidence-based assessment methods enable early detection of motor abnormalities and allows for early treatment. To provide safe and equal care, all professionals performing developmental surveillance should use evidence-based assessment methods.

Indiana University-Purdue University Indianapolis (IUPUI) / In this study we compared the distribution of HPV types in cervical cancer specimens from women living in either Indiana or Botswana. Paraffin-embedded blocks of formalin-fixed cervical cancer specimens were identified from women living in Indiana (n=51) or Botswana (n=171)