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  • About
  • The Global ETD Search service is a free service for researchers to find electronic theses and dissertations. This service is provided by the Networked Digital Library of Theses and Dissertations.
    Our metadata is collected from universities around the world. If you manage a university/consortium/country archive and want to be added, details can be found on the NDLTD website.
1

Erectile dysfunction following pelvic fracture

Gdeh, Daou January 2017 (has links)
A research report submitted to the Faculty of Health Sciences at the University of the Witwatersrand in partial fulfillment of the requirements for the qualifications of MMed (Urology) 2017 / Background: Erectile dysfunction is one of the most important sequelae of pelvic fractures and may be transient or permanent. It can range from weak erections to severe sexual dysfunctions. Importantly, erectile dysfunction is more prevalent when the pelvic fracture is associated with urethral injury. Methods:  This was a retrospective study of patient records, with a prospective questionnaire arm for patients admitted to the hospitals with a pelvic fracture between 01/07/2011 to 30/04/2015.  The electronic databases of the Orthopedic Department at Helen Joseph Hospital and the Male Sexual Dysfunction Clinic at Charlotte Maxeke Johannesburg Academic Hospital were accessed for patients' contact details, by using the name and hospital number of each patient.  Each patient was contacted telephonically with an open speaker in a presence of a witness/translator. The information sheet was read to the patient before the telephonic consent was obtained.  After consent was obtained, patients were asked to verbally complete the International Index of Erectile Function score questionnaire. Results A total of 53 patients participated in the study, of which (43.4%) reported erectile dysfunction. The majority of patients indicated a recovery of erectile function between 2 8 | P a g e to 8 months after the injury. Most were found to still suffer from other forms of sexual impairment like orgasmic dysfunction and sexual satisfaction. However, sexual desire seemed to be preserved. Patients with sexual dysfunction were more likely to have had a urethral injury as well as a more severe fracture. Conclusions In our sample of 53 patients almost half reported sexual dysfunction after a pelvic fracture. Importantly, patients with urethral damage and a severe pelvic fracture should be followed up, as the risk of sexual dysfunction is high in these particular patients. / MT2017
2

The prevalence of the metabolic syndrome in men presenting with erectile dysfunction at a South African tertiary care centre

Wood, Bradley Ryan 22 October 2010 (has links)
MMed (Urology), Faculty of Health Sciences, University of the Witwatersrand / The metabolic syndrome has recently become one of the major public health challenges and results from the increasing prevalence of obesity. Erectile dysfunction (ED) affects up to half of men over the age of forty. Men with co-morbid disease and risk factors including cardiovascular disease, hypertension, dyslipidaemia and depression all report a higher prevalence of ED. The current study investigated the prevalence of the metabolic syndrome in one hundred men with (ED) presenting to the Male Sexual Dysfunction Clinic at the Johannesburg Hospital. Participants underwent a thorough history taking and examination session which included the International Index of Erectile Function Score. Several fasting biochemistry and hormonal tests were performed. Participants were divided by race into three groups. Data was recorded in EXCEL and reported as mean±std or as a number (frequency). Where applicable, correlation between variables was determined. The prevalence of the metabolic syndrome was 39%, with the highest prevalence (54%) in the group comprising Asian, Coloured and Chinese participants. Eighty percent of participants had moderate-severe (ED), with a mean duration of 3,8 years. Glucose and HbA1c were strong predictors of ED duration. Severity of ED was not influenced by the presence of the metabolic syndrome. Men presenting with ED may represent an ideal patient group to screen for the metabolic syndrome, and therefore for cardiovascular disease, especially for those men within the asymptomatic period.
3

Comparison of Marketing Strategies of Oral Erectile Dysfunctional Medicines in Taiwan

T. Wu., Tony 22 May 2004 (has links)
Background and Purpose: The Massachusetts Male Aging Study found 52% of men aged 40 to 70 years suffered from erectile dysfunction (ED). Approximately two millions men in Taiwan were ED suffers, only 10% of them had taken Viagra®. The potential market is very attractive to pharmatheutical industry. By law, ED medicines are prescriptive drugs; in practice, more than 80% of ED drugs were sold without prescription in Taiwan. The launch of Levitra® and Cialis® has boosted the competition in the ED drug market. The purposes of this study are 1) to compare the marketing strategies of Viagra®, Levitra® and Cialis®, 2) to analyze factors influencing physicians¡¦ prescription, 3) to analyze factors affecting drug purchasers¡¦ decision, and 4) to survey the preference of drugstores owners on selling these drugs. Materials and Methods: The first step is face-to-face, in-depth interviews with product mangers to understand their marketing strategies. We will ask them to rate the significance of factors (e.g. efficacy, safety, price) affecting physicians¡¦ and patients¡¦ preference. Product mangers will be requested to rate the importance and relevance of the way product messages delivered to doctors¡¦ prescription behaviors. Questionnaires will be mailed to all urologists in Taiwan to survey factors they concerned when prescribing. We use mailing questionnaires and face-to-face interviews to assess the impact of drug efficacy, duration, safety, etc. on drug purchasers¡¦ decision. Drugstores owners will be interviewed to understand their favor in promoting certain drug. Comparative studies will be done to evaluate the difference between product mangers, physicians and patients. Results The marketing strategy of Pfizer is to emphasize the well-documented efficacy and long-term safety of Viagra® by seminars for physicians. Educational talks will be given to the public to explore the potential consumers. The goal of Bayer is to urge the silent ED suffers search for medical help, and to convince physicians that Levitra® is the drug of choice for ED patients. Eli-Lilly put almost all their marketing efforts and resources in drugstores. Drug efficacy and safety are most important factors influencing physicians¡¦ prescription. Approximately 85% of urologists surveyed favor Viagra®, 21% have safety concern on Cialis®. Most urologists considered Levitra® as alternative of Viagra® when failed. All product mangers overestimate the impact of key opinion leaders, literature, and seminars on physicians¡¦ prescription behaviors. Patients¡¦ survey disclosed that drug efficacy and safety are most important factors affecting drug purchasing. As compared to physicians, patients have more concern on the time of onset and duration. About 20% of drug purchasers are not ED suffers; 62% of purchasing is sporadic, one third of Viagra® users have the attempt to try other ED drugs. The drugstores owners have no specific preference for any drugs. Conclusions The extension of life expectancy and open discussion of male ED problem had resulted in tremendous growth of ED drug market. The launch of new drug may stimulate the selling amount in short run; the long-term market shares depend mainly on the drug efficacy and safety. In our study, we found that safety profile is the main concern for both physicians and drug purchasers. We believed that Viagra® may stay as the market leader, while Levitra® may have only small market share. Certain groups of drug purchasers, especially fake ED suffers and those who with multiple sex-partners will have high brand loyalty to Cialias®.
4

Mannens sexualitet efter genomgången prostatacancerbehandling : En litteraturbaserad studie / Male sexuality after treatment for prostatecancer : A litterature review

Jansson, Anna, Olsson, Linda January 2012 (has links)
No description available.
5

The experimental effects of pill attribution on sexual performance anxiety and subsequent erectile performance

Pujols, Yasisca 20 September 2013 (has links)
Erectile performance anxiety (EPA) is a subset of sexual anxiety characterized by a fear of erectile failure. EPA has been shown to play a pivotal role in male sexual problems including premature ejaculation and erectile dysfunction (Loudon, 1998; Perelman, 2006). EPA affects approximately 14% to 23% of U.S. men across age groups (Laumann, Paik, & Rosen, 1999), and is the most common proximal cause of psychogenic ED (Hale & Strassberg, 1990; Hedon, 2003; Perelman, 1994; Rosen, 2001). Phosphodiesterase type 5 (PDE5) inhibitors such as sildenafil citrate (brand-name Viagra) are the first line of pharmacological treatment for ED. Recreational use of PDE5 inhibitors -- defined as unprescribed use with the goal of sexual enhancement and prevention of erectile failure among men without clinically significant erectile difficulties. Approximately 13.4% of young men between the ages of 18 - 30 report using PDE5 inhibitors recreationally. The most commonly reported reason for off-prescription use is to enhance one's sexual performance, i.e., longer lasting erections or impress one's sexual partner (Bechara, Casabe, De Bonis, Helien, & Bertolino, 2010; Harte & Meston, 2011; Holt, 2009; Korkes, Costa-Matos, Gasperini, Reginato, & Perez, 2008; Musacchio, Hartrich, & Garofalo, 2006). Reducing anxiety -- specifically EPA is often given as a reason for recreational use, though to a lesser extent (Korkes et al., 2008; Schnetzler, Banks, Kirby, Zou, & Symonds, 2010). However, PDE5 inhibitors do not exert a significant increase in penile tumescence among men without erectile dysfunction (Mondaini et al., 2008). The actual sexual enhancement from recreational use of PDE5 inhibitors among this population would be limited in that blood flow to the healthy erectile tissue is already optimal. The proposed study aimed to examine the effects of an erection-enhancing pill description misattribution on anticipatory anxiety and subsequent subjective and physiological sexual response to an audiovisual erotic stimulus. Participants underwent two assessments of their subjective and physiological arousal response to an erotic film after randomization to one of three conditions (erection-enhancing pill description, memory-enhancing pill description, or a no pill control). It was hypothesized that compared to those in the memory-enhancing pill group and the no pill control group, participants in the erection-enhancing pill group would respond with greater anticipatory anxiety and dampened penile tumescence in response to a subsequent no-pill erotic film presentation. Results of the study provided partial support for the hypothesized negative effects of the pill attribution manipulation. In the subset of subjects with complete pre and post-manipulation physiological data, those led to believe they ingested an erectile-enhancing herb showed a dampening of erectile tumescence to a subsequent erotic film presentation. Also, consistent with prediction, erectile performance anxiety was associated with decreased tumescence after the bogus "average" erectile performance feedback compared to baseline. These findings suggest that pill attribution may influence sexual arousal to some extent, despite methodological issues such as partial physiological data loss and believability of the pill instructional set manipulation. / text
6

Effects of smoking cessation on sexual health in men

Harte, Christopher Brookes 07 November 2011 (has links)
Cigarette smoking represents the most preventable cause of morbidity and mortality in the world today, and is responsible for enormous health-related economic burdens. Among other medical sequelae, erectile impairment has been shown to be associated with chronic tobacco use. The primary aim of the present study was to provide the first empirical investigation of the effects of smoking cessation on physiological and subjective indices of sexual health. Sixty-five long-term, heavy smoking men participated in a smoking cessation program and were assessed at baseline (while smoking regularly), at mid-treatment (while using a high dose nicotine transdermal patch), and at 4-week follow-up. Physiological and subjective sexual arousal indices, as well as self-reported sexual functioning (as measured by the International Index of Erectile Functioning (IIEF)) were assessed during each visit. Intent-to-treat analyses indicated that at followup successful quitters (n = 20), compared to those who relapsed (n = 45), showed significant improvements in physiological and subjective sexual arousal. Specifically, men demonstrated enhanced erectile responses, decreased latencies to reach maximum erectile capacity, and faster onset to reach maximum subjective sexual arousal. Although participants displayed across-session enhancements in self reported sexual function, successful quitters did not show a differential improvement compared to participants who relapsed. The results of the present investigation provide the first empirical evidence that smoking cessation significantly enhances both physiological and self-reported indices of sexual health in long-term male smokers, irrespective of baseline erectile impairment. It is hoped that these results may serve as a novel and enticing means to influence men to quit smoking. Increasing successful smoking cessation in men would significantly enhance quality of life, substantially reduce premature death, and alleviate enormous economic burdens caused by smoking-related diseases. / text
7

Diagnosis of erectile dysfunction can be used to improve screening for Type 2 diabetes mellitus

Carrillo-Larco, Rodrigo M., Luza-Dueñas, Anais Casandra, Urdániga-Hung, Mónica, Bernabe-Ortiz, Antonio 11 1900 (has links)
Aims: To assess the diagnostic accuracy of four undiagnosed Type 2 diabetes mellitus risk scores accounting for erectile dysfunction status. Methods: This was a population-based cross-sectional study. Type 2 diabetes was defined according to a oral glucose tolerance test and self-reported physician diagnosis. Erectile dysfunction was defined according to the answer to the question, ‘Have you had difficulties obtaining an erection in the last 6 months?’ (yes/no). The risk scores used were the FINDRISC, LA-FINDRISC, American Diabetes Association score and the Peruvian Risk Score. A Poisson regression model was fitted to assess the association between Type 2 diabetes and erectile dysfunction. The area under the receiver-operating characteristic curve was estimated overall and by erectile dysfunction status. Results: A total of 799 men with a mean (sd) age of 48.6 (10.7) years were included in the study. The overall prevalence of Type 2 diabetes was 9.3%. Compared with healthy men, men with Type 2 diabetes had 2.71 (95% CI 1.57–4.66) higher chances of having erectile dysfunction. Having excluded men aware of Type 2 diabetes status (N=38), the area under the receiver-operating characteristic curve of three of the risk scores (not the American Diabetes Association score) improved among those who had erectile dysfunction in comparison with those who did not; for example, the area under the receiver-operating characteristic curve of the LA-FINDRISC score was 89.6 (95% CI 78.7–99.9) in men with erectile dysfunction and 76.5 (95% CI 68.5–84.4) overall. Conclusions: In a population-based study, erectile dysfunction was more common in men with Type 2 diabetes than in the otherwise healthy men. Screening for erectile dysfunction before screening for Type 2 diabetes seems to improve the accuracy of well-known risk scores for undiagnosed Type 2 diabetes. / Antonio Bernabe-Ortiz is a Research Training Fellow in Public Health and Tropical Medicine (103994/Z/14/Z), funded by the Wellcome Trust. / Revisión por pares
8

Erectile dysfunction: heritability and cognitive and physiological correlates of the subclinical vascular disorder

Moore, Caitlin 28 November 2015 (has links)
The broad goals of this dissertation were to explore possible causes of erectile dysfunction (ED), and examine outcomes associated with the condition. To address these objectives, data from the Vietnam Era Twin Study of Aging (VETSA), a longitudinal study of cognitive aging, were utilized. Previous research demonstrated moderate heritability of ED in middle-aged men, but questions remain about the replicability of these findings given that only one study exists on the topic and it utilized an unvalidated ED measure. Additionally, it is unknown to what extent genetic factors account for stability and change of ED symptomatology over time. In the first study, we conducted a longitudinal assessment of ED using the Sexual Health Inventory for Men (SHIM) administered to 668 male twins. Results revealed that the heritability (proportion of variance explained by genetic factors) of ED at both time points is moderate (0.3 –0.6). Over the past two decades ED has been recognized as primarily a disorder of vascular dysfunction. Inflammation is an important correlate of vascular dysfunction. Chapter 2 examined the association of ED with four inflammatory serum protein indices [albumin, globulin, albumin/globulin ratio (AGR), and the albumin*globulin interaction (AGI)] in 388 men free from cardiovascular disease (CVD). Results indicated that the AGR, albumin, and globulin protein levels are significantly associated with ED, even after accounting for other risk factors. Intriguingly, AGR and globulin levels were found to be more strongly associated with ED than conventional vascular risk factors, such as hypertension, high cholesterol, obesity, and smoking. As such, globulin and AGR may be useful biomarkers when diagnosing and managing ED. The simplicity and affordability of these assays make these markers particularly valuable. Given the negative impact that vascular disease has on cognition, Chapter 3 explored whether men with ED are at greater risk for experiencing cognitive decline compared to healthy peers. In total, 485 men free from CVD were administered cognitive tests across 13 domains. Tests were readministered 5 years later. Results revealed that men with ED were more likely to show significant decline on tasks of set-shifting, tool/mechanical knowledge, vocabulary, and verbal fluency.
9

A visão bioética diante do comportamento social na evolução do tratamento da disfunção erétil

Abreu, Ana Carolina de 14 December 2015 (has links)
Submitted by Natalia Vieira (natalia.vieira@famerp.br) on 2016-05-19T21:52:28Z No. of bitstreams: 1 anacarolinadeabreu_dissert.pdf: 490120 bytes, checksum: 25e56f07305d458ef011d69e87061a78 (MD5) / Made available in DSpace on 2016-05-19T21:52:28Z (GMT). No. of bitstreams: 1 anacarolinadeabreu_dissert.pdf: 490120 bytes, checksum: 25e56f07305d458ef011d69e87061a78 (MD5) Previous issue date: 2015-12-14 / Since ancient times to nowadays, the Erectile Dysfunction has been considered a condition that has always affected men. It has been not only a reason for embarrassment, but also an issue of multifactorial cause related either to psychological or organic and drug factors. For this reason, a significant impact can be observed on the individuals quality of life and their partners while this is associated with low self-esteem, depression, difficult relationship and increased anxiety. As this issue is currently a bioethical matter, it is feasible and necessary to be solved. Its main focus is the principle of life protection; introduced into the Ethics of scientific progress and outlining the guiding and protective limits of the person. There is also the autonomy of the individual's will which has valued the man according to his own individuality as a human being with rationality and liberty. The majority of individuals are not well informed. They search also for easier or less embarrassing ways for treatment and solutions. As a result, it is up to them to choose, "searching for a skilled professional", or a searching for Websites, mysticisms and charlatan. Thus, this study by means of a search on databases such as Pubmed Index, Google and Google Scholar shows publications and data research approaching Erectile Dysfunction from 1930 to today. / Desde os tempos antigos até os dias de hoje, a Disfunção Erétil tem sido considerada uma condição que sempre afetou os homens. É não só um motivo para constrangimento, mas também uma questão de causa multifatorial e tem relação tanto a fatores, psicológicos, biológicos ou medicamentosos. Por esta razão, um impacto significativo pode ser observado na qualidade de vida dos indivíduos e suas parceiras e assim associada à diminuição da autoestima, depressão, difícil relacionamento e aumento da ansiedade. Como esta questão é atualmente de caráter bioético, torna-se oportuna e necessária para ser solucionada, esta nova ciência da vida. Seu foco principal é o princípio da proteção da vida; introduzido na ética do progresso científico e delineando os limites orientadores e protetores à pessoa. Há também a autonomia da vontade do indivíduo que tem valorizado cada um, segundo, a sua própria individualidade como um ser humano com racionalidade e a liberdade. A maioria dos indivíduos não está bem informada. Eles procuram formas mais fáceis ou menos embaraçosas para o tratamento e soluções. Como resultado, cabe-lhes escolher, “pela busca de um profissional capacitado", ou uma busca em sites, misticismos e popularismo. Assim, este estudo por meio de uma pesquisa em bases de dados indexadoras como Pubmed, Google e Google Scholar mostra publicações e dados de pesquisa sobre Disfunção Eréctil de 1930 até os dias atuais.
10

Η μελέτη της στυτικής δυσλειτουργίας σε ασθενείς με χρόνια αποφρακτική πνευμονοπάθεια που κατά τη διάρκεια του ύπνου εμφανίζουν σημαντικού βαθμού αποκορεσμό της αιμοσφαιρίνης

Καρκούλιας, Κυριάκος 05 December 2008 (has links)
Σκοπός: 1) Η μελέτη της επίπτωσης της στυτικής δυσλειτουργίας σε ασθενείς με σύνδρομο επικάλυψης ( ΣΑΑΥ και ΧΑΠ ) και η συγκρισή της με την επίπτωση της στυτικής δυσλειτουργίας σε ασθενείς που παρουσίαζαν μόνο ΣΑΑΥ, και 2) η εκτίμηση της βελτίωσης της στυτικής δυσλειτουργίας (ED) σε άνδρες με σύνδρομο επικάλυψης (αποφρακτική άπνοια του ύπνου και χρόνια αποφρακτική πνευμονοπάθεια) υπό θεραπεία με cPAP (συνεχής θετική πίεση αεραγωγών) και βρογχοδιασταλτικά. Υλικό και μέθοδος : Μελετήθηκαν 48 άνδρες με μέσο όρο ηλικίας τα 52.8 + 10 χρόνια με αποφρακτική άπνοια του ύπνου (ΣΑΑΥ) και χρόνια αποφρακτική πνευμονοπάθεια (ΧΑΠ) και παράλληλα στυτική δυσλειτουργία ED. Επίσης 30 άνδρες με στυτική δυσλειτουργία και ΣΑΑΥ χωρίς αποφρακτική νόσο. Έλαβαν την κατάλληλη θεραπεία για αποφρακτική πνευμονοπάθεια (cPAP και βρογχοδιασταλτικά) για 6 μήνες και έπειτα το επίπεδο της στυτικής λειτουργίας (EF) επανεκτιμήθηκε. Η ED θεωρήθηκε ότι βελτιώθηκε εάν ο βαθμός βελτίωσης (score) αυξήθηκε για τουλάχιστον 5 μονάδες σε σύγκριση με αυτό της βασικής τιμής. Οι καθοριστικοί παράγοντες για βελτίωση της ED επίσης εκτιμήθηκαν, καθώς επίσης και ο βαθμός ικανοποίησης του κάθε ασθενή κατά τη διάρκεια της θεραπείας Αποτελέσματα : Η επίπτωση της ED σε ασθενείς με σύνδρομο επικάλυψης ήταν 81,08%. Η επίπτωση της ED σε ασθενείς πάσχοντες από ΣΑΑΥ και ED ήταν 29,17%. Η ED βελτιώθηκε σε 12 ασθενείς (25%), αλλά μόνο τα 2 /3 αυτών ήταν ικανοποιημένοι με τον βαθμό βελτίωσης μετά από θεραπεία. Η βελτίωση της ED συσχετίστηκε θετικά με την ηλικία, δείκτη άπνοιας / υπόπνοιας και αρνητικά με την διάρκεια της ED. Το score της ED, ο κορεσμός της αιμοσφαιρίνης σε Ο2 κατά τη διάρκεια της νύχτας και το BMI δεν συσχετίστηκαν σημαντικά με το βαθμό βελτίωσης της EF. Συμπεράσματα : 1) Η επίπτωση της ED σε ασθενείς με σύνδρομο επικάλυψης είναι μεγαλύτερη συγκριτικά με αυτή των ασθενών που έπασχαν μόνο από ΣΑΑΥ και συγκριτικά με το γενικό πληθυσμό. 2) Η συνήθης θεραπεία σε ασθενείς με ΣΑΑΥ και ΧΑΠ με βρογχοδιασταλτικά και cPAP έχει θετικά αποτελέσματα στην παράλληλη ED στην μειονότητα των ασθενών αυτών. Από τους άνδρες που βελτιώθηκαν, 1/3 από αυτούς δεν ήταν ικανοποιημένοι με το αποτέλεσμα αυτής της θεραπείας. Διαφορετική θεραπευτική αντιμετώπιση ή συνδυασμός αγωγής θα πρέπει πιθανά να χορηγηθεί στους ασθενείς αυτούς. / Aim: 1) To determine the prevalence of erectile dysfunction in patients with overlap syndrome (obstructive sleep apnea and chronic obstructive pulmonary disease) compared with patients suffered from sleep apnea syndrome and erectile dysfunction and 2)To assess the improvement of concurrent erectile dysfunction (ED) in these patients treated with continuous positive airway pressure (cPAP) and bronchodilators Material and Methods: We evaluated 48 men suffering from OSA, COPD and concurrent ED, and 30 men suffered from OSA and ED. They were treated with conventional therapy for pulmonary obstructive disease (cPAP and bronchodilators) for 6 months and then their erectile function status was reassessed. ED was considered as improved, if ED intensity score increased for at least five points compared to that of baseline. Results: The prevalence of ED in patients with overlap syndrome was 81,08%. The prevalence of ED in men with OSA was 29,17%. ED was improved in 12 patients (25%), but only two thirds of them were satisfied with the grade of improvement after treatment. ED improvement was related positively with age and apnea/hypopnea index and negatively with ED duration. ED intensity score, O2 saturation at night and BMI were not significantly related to the outcome of EF improvement. Conclusions: 1) The prevalence of ED in patients with overlap syndrome was higher compared with the prevalence of ED in men with OSA. 2) Conventional treatment for OSA and COPD, has a positive effect on concurrent ED on the minority of patients. The effect is possibly due to the improvement of respiration during sleep with cPAP and of oxygenation with bronchodilators continuously

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