Considering the permanent nature of the built environment, this dissertation investigates an alternative approach towards static architecture. Allowing the building’s users the ability to alter and determine their own environments due to ever evolving social needs. This architectural approach is thereafter metaphorically condensed to formulate a programme between isolation (prison) and freedom (society), where parolees are temporarily housed and given the opportunity to implement the production skills that were developed in prison. Allowing these parolees a second chance for redemption and the opportunity to ‘give back to society’ through the production process of recyclable waste into new sustainable products. The architectural concept should be understood in various different time scales over which the building changes, thus designing for disassembly by utilising a modular and kit-of-parts approach. / Dissertation (MArch(Prof))--University of Pretoria, 2011. / Architecture / unrestricted

Fibromyalgia has a significant impact on the lives of patients; symptoms are influenced by psychological factors, such as psychological flexibility and catastrophizing. The objective of this study was to determine the importance of these variables in moderating the association between the severity and impact of fibromyalgia symptoms. A total of 187 patients from a general hospital population were evaluated using the Combined Index of Severity of Fibromyalgia (ICAF), the Fibromyalgia Impact Questionnaire (FIQ), the Acceptance and Action Questionnaire-II (AAQ-II), and the Pain Catastrophizing Scale (PCS). A series of multiple regression analyses were carried out using the PROCESS macro and decision tree analysis. The results show that psychological flexibility modulates the relation between severity and the impact of fibromyalgia symptoms. Catastrophism has residual importance and depends on the interaction with psychological flexibility. Interaction occurs if the severity of the disease is in transition from a mild to a moderate level and accounts for 40.1% of the variance in the sample. These aspects should be considered for evaluation and early intervention in fibromyalgia patients.

Eating disorders have a dramatic effect on the lives of people who struggle with them, including cardiovascular and gastrointestinal problems, and death. Individuals with these diagnoses are also often struggling with comorbid diagnoses such as depression, anxiety, and substance abuse/dependence. Building on a conceptualization of eating disorders as a means to dysfunctionally regulate negative affect and escape unwanted thoughts, psychological flexibility, the ability of a person to contact unwanted thoughts or feelings and behave without escape or avoidance, is investigated as a tool for treatment. Additionally, because quantitative analysis of the construct of psychological flexibility has often employed the use of college samples, this study employed a sample of participants drawn from a residential treatment facility dedicated to the treatment of eating disorders. Through regression and modeling, psychological flexibility demonstrates its utility in the treatment of eating disorders through its relationship with body dissatisfaction and quality of life.

The present study implemented quantitative (Phase I) and qualitative (Phase II) analyses to investigate the relationships that the constructs of psychological flexibility (PF) and psychological inflexibility (PI) had with helping profession trainees’ experience of conflict in clinical supervision, conflict management styles, and ratings of the quality of the supervisoryrelationship. Phase-I results (n = 290) revealed no relationship between conflict prevalence, frequency, or distress with overall levels of PF and PI. However, secondary analyses suggested individual components of PF and PI as measured by the Multidimensional Psychological Flexibility Inventory (MPFI; Rolffs et al., 2016) may be related to these constructs, including Defusion, Self as Context, Values, Fusion, Lack of Contact with Values, and Inaction. Participants’ levels of PF and PI predicted most conflict management styles. PF was especially related to the Integrating style and PI was especially related to the Avoiding style. Participants’ levels of PF were also positively correlated with the quality of the supervisory relationship. Phase II results from semi-structured interviews interpreted via the Listening Guide method revealed relationships between four participants’ experiences of conflict in supervision and components of PF and PI. Three themes emerged across the interviews: negative affect, inexperience, and accepting responsibility. Qualitative findings were also related to various components of PF and PI, especially Self as Context, Experiential Avoidance, and Fusion.

The North American forest products industry is primarily commodity-based and faces challenges. This has led to the proposal of a shift toward revenue diversification through the production of high-value specialty products along with the conventional commodity products. A key consideration for this new business strategy to remain competitive and sustainable is that the forest products supply chain designs must perform satisfactorily under the dynamic market conditions. The notion of supply chain operability attempts to characterize the ability of a supply chain to perform satisfactorily in the face of uncertainty. However, limited quantitative analysis is available in the current body of literature. In this work, the concepts originated within the context of process systems engineering are adapted to develop optimization-based frameworks in order to characterize supply chain operability measures, in particular, supply chain flexibility and dynamic responsiveness. Although motivated by the forest products industry, the practical mathematical formulations presented are widely applicable to general process supply chains in other industries. This thesis aims to extend the supply chain flexibility analysis formulation established by Mastragostino (2012) to include additional quantitative flexibility measures. The resulting framework provides a quantitative mapping to various types of flexibility frequently discussed in the operations research literature. Two case studies are included to illustrate the application of this framework for analyzing the flexibility of existing supply chain processes, as well as utilizing it in supply chain design. The work also builds on the analysis framework established by Mastragostino and Swartz (2014) to assess supply chain responsiveness, and to configure the framework in preparation for tackling design problems under uncertainty. Then a composite operability analysis framework is proposed to address both flexibility and responsiveness metrics simultaneously in forest products supply chain design and operation. A comprehensive case study based on a forest product company is performed and the trade-offs among flexibility, responsiveness and economics are examined. / Thesis / Master of Applied Science (MASc)

Gymnasts must attain extreme ranges of flexibility to execute performance requirements, thus effective stretching proves vital to advancement in the sport. This study examined the acute effects of whole-body vibration (WBV) on passive and dynamic flexibility in young, female gymnasts. Participants (n = 27, Junior Olympic levels 5-10) served as their own control. Measurements of passive and dynamic flexibility were obtained using the TOPS forward split testing method to examine passive flexibility and dynamic flexibility was measured via split jumps that were analyzed with video and Dartfish software. According to randomized order, all participants completed a stretching protocol either with the WBV platform turned on (VIB) or off (C) separated by 48 h. Participants performed 4 sets of three stretches on the WBV platform. An ANCOVA was performed (using height, weight, age, years of experience, and gymnastics level as covariates). Significant improvements were found in passive flexibility for both VIB and C conditions, but there was no significant difference between the two stretching conditions (p = 0.17). The maximum split jump decreased significantly from pre to post measurement in both the VIB (p < 0.0001) and C (p = 0.04) conditions. VIB decreased the split jump significantly more than C. Based on the results of our study, an acute session of static stretching or stretching with WBV immediately before performance decreases split jump performance. Therefore, this WBV protocol is not recommended immediately prior to gymnastics competition.

The estimated lifespan of a building today is only 50 years. They are often designed down to the minimum for a specific target group or one specific use. In many cases constructed with load-bearing walls that divide function-specified rooms, making conversion into any other form of function impossible. Locking buildings to a specific function is not very clever, as buildings are subject to a wide range of trends and changes.  The goal of this project has been to investigate how the built environment can be resilient to changing societal trends to avoid becoming obsolete and in the worst case having to be demolished. This leads to the question of how a building can be designed to enable change and how to build and plan a building when its future use and users are unknown.

Reconfiguration refers to the ability of a flexible structure to change its shape, allowing it to reduce its area perpendicular to the flow, to reduce drag. Decreasing the flexural rigidity of human-made structures can lead to improved designs that operate at higher propulsive efficiencies. The work presented in this thesis examines the physics surrounding a flexible plate under prescribed oscillatory heaving motions. White light movies were recorded at constant frequency and varying proximity to the free surface to investigate the change in reconfiguration as the plate approaches the free surface. Results, analyzed in terms of deformed plate shape, deflection, and plate tip kinematics, found that free surface effects increase the deflection of the plate as the plate approaches the free surface. Expanding on the initial experiments, a variety of frequencies were tested. The results show that each heaving frequency has a different critical height to the free surface in which deep water behavior is distinguished from shallow water behavior. At the critical depth, the plate deflection becomes asymmetric due to free surface effects. The second stage of experiments focused on measuring the fluid loading and fluid flow surrounding the flexible plate. The fluid loading, or drag force, acting on the plate was estimated by using a strain gauge load cell. Results of these experiments found that the drag force is equivalent on plates with lower heaving frequencies when compared to the highest heaving frequency tested due to increased reconfiguration at the higher frequency. The fluid moved from the keel to the edge of the plate as seen in the particle image velocimetry experiments. Higher heaving frequencies created faster fluid flow off the plate and stronger tip vortices being shed from the plate. When the flexible plate operated at large distances from the free surface, the fluid dynamics showed the same behavior for the upstroke and downstroke of the plate. Whereas, when the plate operated close to the free surface, a vortex only forms on the upstroke, leading to asymmetric loading and deformations. / Master of Science / The ability for a structure to bend under loading and return to its original shape after the load is removed presents a desirable characteristic for structural design. The flexibility of the structure can lead to significant weight loss in contrast to rigid structures. In nature, almost all structures are able to bend when faced with fluid forces which decreases the loading the structure has to handle. Decreasing the stiffness of human-made structures can lead to improved designs that operate at higher propulsive efficiencies. The work presented here examines the physics surrounding a flexible plate under prescribed oscillatory heaving motions, which are motions that are purely vertical. White light movies were recorded at constant frequency and varying proximity to the free surface to investigate the change in plate shape as the plate approaches the free surface. Results, analyzed in terms of deformed plate shape, deflection, and plate tip kinematics, found that free surface effects increase the deflection of the plate as the plate approaches the free surface. Expanding on the initial experiments, a variety of frequencies were tested. The results show that each heaving frequency has a different critical height to the free surface in which deep water behavior is distinguished from shallow water behavior. At the critical depth, the plate deflection becomes asymmetric due to free surface effects. The second stage of experiments focused on describing the fluid loading and fluid flow surrounding the flexible plate. The fluid loading, or drag force, acting on the plate was estimated by using a strain gauge load cell. Results of these experiments found that the drag force is equivalent on plates with lower heaving frequencies when compared to the highest heaving frequency tested due to increased reconfiguration at the higher frequency. The fluid moved from the center of the plate to the edge of the plate as seen in the particle image velocimetry experiments, which track the movement of particles in the fluid. Higher heaving frequencies created faster fluid flow off the plate. When the flexible plate operated at large distances from the free surface, the fluid flow showed the same behavior for the upstroke and downstroke of the plate. Whereas, when the plate operates close to the free surface, the fluid flow behaves differently leading to asymmetric loading and deformations.

Proteins are dynamic molecules involved in virtually every chemical process in our bodies. Understanding how they flex and bend provides fundamental insights to their functions. At the atomic level, protein motion cannot be observed using existing experimental methods. To gain insights into these motions, simulation methods are used. However such simulations are computationally expensive. Rigidity analysis is a fast, alternative graph-based method to molecular simulations, that gives information about the flexibility properties of molecules modeled as mechanical structures. Due to the lack of convenient tools for curating protein data, the usefulness of rigidity analysis has been demonstrated on only a handful of proteins to infer several of their biophysical properties. Previous studies also relied on heuristics to determine which choice of modeling options of important stabilizing interactions allowed for extracting relevant biological observations from rigidity analysis results. Thus there is no agreed-upon choice of modeling of stabilizing interactions that is validated with experimental data. In this thesis we make progress towards large-scale validation of protein flexibility using rigidity analysis. We have developed the KINARI software to test the predictive power of using rigidity analysis to infer biophysical properties of proteins. We develop new tools for curating protein data files and for generating biological functional forms and crystal lattices of molecules. We show that rigidity analysis of these biological assemblies provides structural and functional information that would be missed if only the unprocessed data of protein structures were analyzed. To provide a proof-of-concept that rigidity analysis can be used to perform fast evaluation of in silico mutations that may not be easy to perform in vitro, we have developed KINARI-Mutagen. Finally, we perform a systematic study in which we vary how hydrogen bonds and hydrophobic interactions are modeled when constructing a mechanical framework of a protein. We propose a general method to evaluate how varying the modeling of these important inter-atomic interactions affects the degree to which rigidity parameters correlate with experimental stability data.

Seismic isolation is a method of earthquake resistant design which has been proven to effectively reduce the damaging effects of earthquakes on buildings as well as the contents within them. However, traditional implementation of an isolation system tends to be expensive. For new construction, rigid diaphragms above and below the isolation layer and construction of a seismic gap contribute to expenses, while retrofit applications also require excavation beneath the building and may need extensive foundation work. To mitigate these major costs bearings may be placed on the tops of columns, forgoing the construction of a seismic gap, additional rigid diaphragm, and foundation work. However, columns under the isolation layer may be flexible, changing the bearing end conditions traditionally assumed. To investigate the effects of flexible end conditions on elastomeric bearings, an analytical model that accounts for translation and rotation of both endplates was developed based on Haringx's theory. The derivation accounts for compressibility of the rubber and results in a simple stiffness matrix. To evaluate the model, an experimental program testing column-bearing subassemblies under quasi-static cyclic conditions was conducted. Experimental findings show that flexible end conditions can significantly reduce the lateral stiffness of elastomeric bearings. Simulations with the theoretical model compare well under small deformations, but elastic softening of the moment-rotation relationship causes theoretical results to diverge from experimental with larger endplate rotations. The effectiveness of column-top isolation as a retrofit strategy was investigated through nonlinear time history analyses of a moment resisting frame designed to the 1965 National Building Code of Canada and retrofitted with column-top isolation. The frame was simulated under ground motions representative of current hazards and showed that the retrofit resulted in significant reductions in interstory drifts and floor accelerations. Yielding was observed throughout the original frame under maximum considered earthquakes, while the retrofit frame remained elastic. / Thesis / Master of Applied Science (MASc)