Rehabilitation of edentulous patients with Implant-supported Complete Fixed Dental Prosthesis (ICFDP) is a well-documented treatment option. This dissertation assessed the relation between the rate of biological/mechanical complications and the type of metal framework alloy, length of cantilever extension. The results showed that long-term clinical outcomes of ICFDP were favorable. While 30% of patients experienced biological complications, 66.6% of the prostheses needed to be repaired during follow-up period. The risk of prosthesis failure and mechanical complications was significantly higher in silver-palladium frameworks as compared with palladium-silver or type IV gold alloys. The length of cantilever was not correlated with the amount of marginal bone loss. The rate of marginal bone loss around anterior implants was higher than that of posterior implants associated with cantilever segments. The treatment improved the patients’ quality of life and 96% of patients would undergo the same treatment again if required.

Rehabilitation of edentulous patients with Implant-supported Complete Fixed Dental Prosthesis (ICFDP) is a well-documented treatment option. This dissertation assessed the relation between the rate of biological/mechanical complications and the type of metal framework alloy, length of cantilever extension. The results showed that long-term clinical outcomes of ICFDP were favorable. While 30% of patients experienced biological complications, 66.6% of the prostheses needed to be repaired during follow-up period. The risk of prosthesis failure and mechanical complications was significantly higher in silver-palladium frameworks as compared with palladium-silver or type IV gold alloys. The length of cantilever was not correlated with the amount of marginal bone loss. The rate of marginal bone loss around anterior implants was higher than that of posterior implants associated with cantilever segments. The treatment improved the patients’ quality of life and 96% of patients would undergo the same treatment again if required.

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Graduates from 1950 to 2010 with a B.S. degree in animal science from the Department of Animal Science of Texas A&M University were sent questionnaires by e-mail to collect information on how graduates of the department were being influenced in their career decisions by their educational experiences in the department and how they perceived selected components of the program. The questionnaire contained questions about their backgrounds and their careers. It also contained 23 statements to which respondents answered using a 5-point scale from strongly disagree to being strongly agree. Approximately 3,000 questionnaires were e-mailed, and 633 with full data were returned. Male respondents were found to have more agricultural experience than females. Almost half of the males reported that they were in careers related to their animal science degree while slightly more than one-fourth of the females indicated animal science-related careers. Participants who were very experienced in agriculture prior to college were more likely to be in a career related to their animal science degree than were those with other levels of experience. Participants responded with their levels of agreement to statements about their experiences in animal science courses. The statements with the highest level of agreement involved practical, hands-on and generic skills and attributes, industry involvement, and current issues in animal science. Graduates agreed that hands-on involvement with animals in courses and involvement with industry leaders were important. Similarly, they agreed that character, integrity, and work ethic were important attributes to develop in students. Communication skills?both oral and written?were highly important, too. On the other hand, graduates believed that the animal science curriculum did not emphasize creativity and did not provide enough flexibility to emphasize specialized areas of animal science such as companion animals. Continual research about animal science graduates, their academic programs, and their careers is important to track the ever-changing demands and needs of the agricultural industry and of students.

Thesis (M.A.)--University of Missouri-Columbia, 2008. / The entire dissertation/thesis text is included in the research.pdf file; the official abstract appears in the short.pdf file (which also appears in the research.pdf); a non-technical general description, or public abstract, appears in the public.pdf file. Title from title screen of research.pdf file (viewed on August 12, 2009) Includes bibliographical references.

Thesis (doctoral)--University of Lund, 1981.

Thesis (M.S.)--University of Wisconsin. School of Nursing, 1973. / eContent provider-neutral record in process. Description based on print version record.

No período de 2008 a 2010, foi realizado o estudo de Atenção Farmacêutica, prospectivo longitudinal, com a participação de 104 pacientes diagnosticados com hipertensão arterial sistêmica, oriundos de duas unidades de saúde, do Distrito Sanitário Oeste da Cidade de Ribeirão Preto/SP. Após seis meses de estudo houve redução estatística significativa nos valores de Pressão Arterial Sistólica e Diastólica com menor dispersividade dos valores e clínica. A adesão ao tratamento aumentou ao longo do acompanhamento. Apresentou-se reduzido risco cardiovascular, com uma redução estatisticamente significativa do escore de risco Framingham. Discreta redução dos atendimentos de emergência. Apesar do sucesso deste estudo, fica em aberto se os benefícios alcançados são considerados transitórios ou permanentes. Para tanto, os pacientes foram reavaliados quanto aos parâmetros: pressão arterial sistólica e diastólica; valores de colesterol total; HDL; LDL, triglicerídeos, número de consultas em geral realizadas nessas unidades de saúde, e número de princípios ativos utilizados. Comparados os dados no período durante e após a Atenção Farmacêutica observou se que houve um aumento estatisticamente significante nos valores de pressão arterial sistólica e diastólica Com relação aos números de medicamentos prescritos houve também um aumento estatisticamente significativo, mas justificável devido à alteração na relação municipal de medicamentos essenciais entre os anos de 2009 e 2012. Quanto ao número de consultas e os resultados dos exames laboratoriais não houve diferença estatisticamente significante. Diante disso, pode se concluir que a Atenção Farmacêutica foi importante para a manutenção e manejo dos pacientes hipertensos e que o período de 30 meses após a Atenção Farmacêutica apresentou discretas alterações, principalmente nos valores de pressão arterial sistólica e diastólica e número de princípios ativos utilizados. / In the period from 2008 to 2010, a longitudinal and prospective Pharmaceutical Care study was conducted with 104 patients diagnosed with hypertension, from two health units, from the West Sanitary District of the municipality of Ribeirão Preto/SP. In this study, in the first six months of follow-up was observed a statistically and clinically significant reduction in the values of systolic and diastolic blood pressure, and with less dispersivity values. Medication adherece increased during the follow-up, a lower coronary risk was presented, with a statistically significant reduction in the Framingham Risk Score. A slight reduction in the emergency room visits was also observed. Considering the success of this study, was not decide whether the benefits obtained were considered transitory or permanent. Therefore patients were reassessed for the parameters: systolic and diastolic blood pressure; total cholesterol; HDL, LDL, triglycerides, number of consultations in general performed in those health units, and number of active moieties. Comparing data from the period during and after the Pharmaceutical Care, it was observed that there was a statistically significant increase in systolic and diastolic blood pressure. Regarding the number of prescribed medications statistically significant increase was also observed, but justifiable due to changes in the municipal list of essential medicines between the years of 2009 and 2012. Regarding the number of medical appointments and the results of laboratory tests there was no statistically significant difference. Thus, it can be concluded that Pharmaceutical Care was important for the maintenance and management of hypertensive patients and that the period of 30 months after the Pharmaceutical Care showed slight alterations, mainly in systolic and diastolic blood pressure and number of active moieties used.

No período de 2008 a 2010, foi realizado o estudo de Atenção Farmacêutica, prospectivo longitudinal, com a participação de 104 pacientes diagnosticados com hipertensão arterial sistêmica, oriundos de duas unidades de saúde, do Distrito Sanitário Oeste da Cidade de Ribeirão Preto/SP. Após seis meses de estudo houve redução estatística significativa nos valores de Pressão Arterial Sistólica e Diastólica com menor dispersividade dos valores e clínica. A adesão ao tratamento aumentou ao longo do acompanhamento. Apresentou-se reduzido risco cardiovascular, com uma redução estatisticamente significativa do escore de risco Framingham. Discreta redução dos atendimentos de emergência. Apesar do sucesso deste estudo, fica em aberto se os benefícios alcançados são considerados transitórios ou permanentes. Para tanto, os pacientes foram reavaliados quanto aos parâmetros: pressão arterial sistólica e diastólica; valores de colesterol total; HDL; LDL, triglicerídeos, número de consultas em geral realizadas nessas unidades de saúde, e número de princípios ativos utilizados. Comparados os dados no período durante e após a Atenção Farmacêutica observou se que houve um aumento estatisticamente significante nos valores de pressão arterial sistólica e diastólica Com relação aos números de medicamentos prescritos houve também um aumento estatisticamente significativo, mas justificável devido à alteração na relação municipal de medicamentos essenciais entre os anos de 2009 e 2012. Quanto ao número de consultas e os resultados dos exames laboratoriais não houve diferença estatisticamente significante. Diante disso, pode se concluir que a Atenção Farmacêutica foi importante para a manutenção e manejo dos pacientes hipertensos e que o período de 30 meses após a Atenção Farmacêutica apresentou discretas alterações, principalmente nos valores de pressão arterial sistólica e diastólica e número de princípios ativos utilizados. / In the period from 2008 to 2010, a longitudinal and prospective Pharmaceutical Care study was conducted with 104 patients diagnosed with hypertension, from two health units, from the West Sanitary District of the municipality of Ribeirão Preto/SP. In this study, in the first six months of follow-up was observed a statistically and clinically significant reduction in the values of systolic and diastolic blood pressure, and with less dispersivity values. Medication adherece increased during the follow-up, a lower coronary risk was presented, with a statistically significant reduction in the Framingham Risk Score. A slight reduction in the emergency room visits was also observed. Considering the success of this study, was not decide whether the benefits obtained were considered transitory or permanent. Therefore patients were reassessed for the parameters: systolic and diastolic blood pressure; total cholesterol; HDL, LDL, triglycerides, number of consultations in general performed in those health units, and number of active moieties. Comparing data from the period during and after the Pharmaceutical Care, it was observed that there was a statistically significant increase in systolic and diastolic blood pressure. Regarding the number of prescribed medications statistically significant increase was also observed, but justifiable due to changes in the municipal list of essential medicines between the years of 2009 and 2012. Regarding the number of medical appointments and the results of laboratory tests there was no statistically significant difference. Thus, it can be concluded that Pharmaceutical Care was important for the maintenance and management of hypertensive patients and that the period of 30 months after the Pharmaceutical Care showed slight alterations, mainly in systolic and diastolic blood pressure and number of active moieties used.

FundaÃÃo de Amparo à Pesquisa do Estado do Cearà / The large use of oxacillin in Brazilian hospitals and the ausence of scientific data confirming its safety, justify the necessity of carrying out well âstructured studies, identifying the existence of possible triggering factors of the reactions. AIM: To study the use of oxacillin and the occurrence of adverse reactions in two different groups, identifying risk factors associated. METHODS: Children using oxacillin were monitorized from October 2000 to July 2001 in the Universitary Hospital Walter CantÃdio (HUWC), as well as ones under treatment with oxacillin of block D from Childrenâs Hospital Albert Sabin in the period of July 2001 and March 2002 (FIRST STUDY). Also, patients under treatment with oxacillin from HUWC, during the period of July until October 2003, were followed up (SECOND STUDY). The follow-up was done through daily visits in the infirmary and analysis of medical records and prescriptions, being observed the clinical history, prescribed drugs, laboratorial exams, oxacillin use, adverse reaction reports related to oxacillin (AROx) and procedures done due to these AROx. The reactions were reported and classified according to causality and gravity (both studies) and hypersensitivity type (in the SECOND STUDY). Statistical tests were used promptly. RESULTS: FIRST STUDY: In 130 children monitorized were observed both a large oxacillin exposure in the masculine sex, being used the oxacillin average dose of 216,3mg/kg/day. The accumulative incidence (AI) of AROx was equal to 20,8%, of the total of 3352 patients-day monitorized (incidence density/ ID = 0,8). Of the 43 reactions reports, the most frequent reactions were fever (50%) and cutaneous rash (35,7%). The procedure more used in the case of occurrence of AROx was the suspension of oxacillin use (51,9%). The most of reactions presented causality and gravity as Probable (55,6%) and Moderate (92,6%), respectively. In addition, the average of exposure time to oxacillin and hospitalization time were significantly different between the groups of patients that presented AROx or no. The relative risk (RR) of oxacillin exposure by more than 14 days was 5,46 to AROx occurrence. SECOND STUDY: Of the 76 patients, 36,8% ones related to allergic antecedents. Of these, 72,5% were associated to use of drugs. Oxacillin was considered as first choice drug for treatment of 75% of patients. The association oxacillin plus ceftazidima was the most used (22%) during treatments. The average dose of oxacillin prescribed was 206mg/kg/day. The average time of treatment with oxacillin was 15 days. The ineffective therapeutic (21,1%) and occurrence of adverse reaction (15,8%) caused the suspension of this antibiotic. The permanence time in the hospital of patients was 32,4% (patients-day total: 2463; ID = 0,97). The most frequent reactions were the increase of transaminases (22,1%), fever (17%) and cutaneous rash (13,6%). The majority of reactions showed causality, gravity and hypersensitivity as Probable (44,1%), Moderate (66,1%) and type B (86,4%). The presence of AROx was frequent between patients with age equal or under 14 years old (P = 0,0159)/ RR = 2,22). The incidence of adverse reactions to other medicaments was higher in the AROx patient group (P = 0,0036)/ RR = 2,66). 34% of followed patients presented at least one drug related problem involving oxacillin (DRPOx). A total of 71 DRPOx was identified. Of these DRPOx, the detection of adverse reactions was predominant (33,8%). CONCLUSION: The careful use of oxacillin is recommended in paediatrics, with duration of treatment established promptly. The empirical and prolonged exposure of this drug should be avoided. / O elevado grau de utilizaÃÃo da oxacilina nos hospitais do Brasil e a inexistÃncia de dados cientÃficos que comprovem sua seguranÃa justificam a necessidade da realizaÃÃo de estudos bem planejados que visem testar a existÃncia de fatores desencadeantes das reaÃÃes. OBJETIVOS: Estudar a utilizaÃÃo da oxacilina e a ocorrÃncia de reaÃÃes adversas em duas populaÃÃes distintas, apontando fatores de risco associados. METODOLOGIA: Foram acompanhadas crianÃas expostas à oxacilina no Hospital UniversitÃrio Walter CantÃdio (HUWC), entre outubro/2000 e julho/2001, e no bloco D do Hospital Infantil Albert Sabin, entre julho/2001 e marÃo/2002 (PRIMEIRO ESTUDO); e tambÃm, os pacientes adultos e as crianÃas expostos à oxacilina no HUWC, no perÃodo de julho a outubro de 2003 (SEGUNDO ESTUDO). O seguimento de pacientes foi feito atravÃs de visitas diÃrias Ãs enfermarias, anÃlise de prontuÃrios e prescriÃÃes, sendo observada a histÃria clinica, medicamentos prescritos, resultados de exames laboratoriais, perfil de utilizaÃÃo da oxacilina, ocorrÃncia de reaÃÃo adversa à oxacilina (RAOx) e procedimentos adotados devido à RAOx. Os casos foram notificados e classificados quanto à causalidade e gravidade (nos dois estudos) e quanto ao tipo de hipersensibilidade (no segundo estudo), sendo realizados testes estatÃsticos pertinentes. RESULTADOS: PRIMEIRO ESTUDO: A amostra foi composta por 130 crianÃas, sendo observada uma maior exposiÃÃo do sexo masculino (56,9%) e uma dose mÃdia de oxacilina utilizada, equivalente a 216,3 mg/kg/dia. A incidÃncia acumulada (IA) de RAOx foi igual a 20,8%, para um total de 3352 pacientes/dia acompanhados (densidade de incidÃncia/ DI = 0,8). De 43 reaÃÃes relatadas, as mais freqÃentes foram febre (50%) e rash cutÃneo (35,7%), A conduta mais utilizada na ocorrÃncia de RAOx foi a suspensÃo do uso da oxacilina (51,9%). A maioria das reaÃÃes tiveram causalidade ProvÃvel (55,6%) e gravidade Moderada (92,6%). As mÃdias do tempo de exposiÃÃo à oxacilina e do tempo de internamento, diferiram significantemente entre os grupos de pacientes com e sem RAOx. O risco relativo (RR) da exposiÃÃo à oxacilina por mais de 14 dias foi de 5,46 para a ocorrÃncia de RAOx. SEGUNDO ESTUDO: Dos 76 pacientes monitorizados, 36,8% referiram antecedentes alÃrgicos, dos quais 72,5% foram atribuÃdos ao uso de medicamentos. A oxacilina foi primeira escolha para o tratamento de 75% dos pacientes monitorizados e a ceftazidima, a associaÃÃo mais utilizada (22%). A dose mÃdia prescrita de oxacilina foi de 206mg/kg/dia e o tempo mÃdio de exposiÃÃo, igual a 15 dias. A ineficÃcia terapÃutica e a ocorrÃncia de reaÃÃo adversa, foram os causadores da suspensÃo do tratamento com oxacilina em 21,1% e 15,8% dos casos, respectivamente. O tempo de internaÃÃo dos pacientes foi em mÃdia 32,4 dias. Observou-se uma IA de RAOx igual a 31,6%, para um total de 2463 pacientes-dia monitorizados (DI = 0,97). As reaÃÃes mais freqÃentes foram: aumento de transaminases (22,1%), febre (17,0%) e rash cutÃneo (13,6%). A maioria das reaÃÃes foi considerada de causalidade ProvÃvel (44,1%), gravidade Moderada (66,1%) e hipersensibilidade do tipo B (86,4%). A ocorrÃncia de RAOx foi mais freqÃente entre os pacientes com idade igual ou menor que 14 anos (P = 0,0159/ RR = 2,22) e a incidÃncia de reaÃÃo adversa a outros medicamentos, foi maior no grupo de pacientes com RAOx (P = 0,0036/ RR = 2,66). Cerca de 34% dos pacientes monitorizados apresentaram pelo menos 01 problema relacionado com medicamento envolvendo a oxacilina (PRMOx), sendo identificado um total de 71 PRMOx, dos quais a ocorrÃncia de reaÃÃo adversa foi o mais freqÃente (33,8%). CONCLUSÃO: Recomenda-se a administraÃÃo cautelosa de oxacilina em crianÃas, com duraÃÃo do tratamento estabelecida, evitando-se tratamento empÃrico e uso prolongado.