Magíster en Artes Mención Dirección Teatral / El proyecto de tesis "Dentro de casa: construcción de una puesta en escena ominosa", consiste en estudiar Lo ominoso, concepto investigado por Sigmund Freud en un texto de 1919, analizando las implicancias estéticas que dicho concepto tiene y que servirán de base teórica para el proyecto creativo de la presente investigación.

The thesis aims to show that, while an interpretive psychology is not compatible with theory as it occurs in the predictive- causal explanation of the natural sciences, it is both possible and necessary to develop a concept of theory valid within an interpretive methodology. These claims are advanced in the course of an examination of Ricoeur 's interpretation of Freudian psychoanalysis. After examining some traditional ways in which phenomenological psychology has responded to the psychoanalytic challenge, the thesis presents an interpretation of Freudian psychoanalysis as a hermeneutic approach which utilized theoretical constructions in a productive way, although distorted by Freud's natural-scientific self- understanding. Freud's causal-explanatory language and natural- scientific meta theory are shown to be significant inasmuch as they provide a vehicle for theory construction in psychoanalysis. However, since the theory is modeled on that of the natural sciences, it proves incompatible with the interpretive aspects of Freud's approach. We then establish a concept of theory and of causal analysis which is different to that of the natural sciences, and is compatible with, and indeed founded in, an interpretive approach to psychology. These concepts are then illustrated in the context of psychoanalysis. In the final chapter the advantages of the use of theory in interpretive psychology are discussed.

D.Litt. et Phil. / Although Freudian theory traditionally constitutes one of the most important approaches to psychotherapy, it has also generated much criticism from different scientific perspectives. An attempt is made in this study to answer the criticisms of the hermeneuticians and the positivists by using the a systemic approach to indicate a possible solution to methodological and theoretical problems which beset Freudian theory and praxis. The This the research procedure was reported as fully as possible. implies that the therapist's theoretical perspectives, case history of the patient, and the complete transcription qualitatively of the sessions are reported. and quantitatively analysed The results were in an integrated approach. The quantitative analysis was done with the use of a computer program called WORDS, which employs a clustering technique to indicate the development of thematic centroids. The qualitative analysis of the sessions indicates the sequential development of the interaction, and also includes the analysis of the free-associations in each session. The conclusions which are reached in this study are constituted, and reflected in the report of the research process itself. The observations, the thoughts, the processes and the patterns together create the picture which is the conclusion.

CC2D1A (coiled-coil and C2 domain containing protein 1A), also known as Freud-1, has been identified as a transcriptional repressor of the serotonin receptor 5-HT1A, a regulator of endosomal budding and an activator of NF-KB signaling. It also acts as a scaffold that promotes activity of the PI3K/Akt pathway upon stimulation by the epidermal growth factor (EGF). Moreover, several studies highlight naturally occurring mutations of CC2D1A in humans that produce varying degrees of intellectual disorder and autism. Use of the Cre-LoxP system to conditionally knockout CC2D1A in mice has provided promising results regarding its effect on 5-HT1A expression and behaviour. This thesis aims to extend the use of this knockout model by studying cell signaling activity in mouse embryonic fibroblasts (MEFs), derived from the CC2D1Aflx/flx transgenic line, that have been treated with a commercially available Cre recombinase to completely knock out CC2D1A. I hypothesize that CC2D1A directly regulates EGF receptor activity and that its Cre-mediated knock down in vitro will entirely block cell signaling pathways activated by the EGF receptor. Western blot analysis demonstrated that, after Cre-mediated CC2D1A knockout, Akt and Erk1/2 phosphorylation were still maintained upon EGF treatment. In addition, overexpressing Freud-1 via transfection had no effect on cell signaling compared to the wild-type control. Analysis of recombinant Freud-1 constructs reveal that a C-terminal truncation enhances its ability to bind to PIP2 and PIP3 – phospholipids essential to the Akt pathway. In addition, immunocytochemistry analysis demonstrates a responsiveness of CC2D1A to EGF treatment. Altogether, these data highlight a unique and effective way in carrying out gene knockout in vitro while also emphasizing the need to further investigate CC2D1A’s importance in regulating cell signaling pathways and functional compensation by other homologous proteins

Orientador : Luiz Roberto Monzani / Tese (doutorado) - Universidade Estadual de Campinas, Instituto de Filosofia e Ciencias Humanas / Made available in DSpace on 2018-07-18T10:13:25Z (GMT). No. of bitstreams: 1 Milidoni_CarmenBeatriz_D.pdf: 89130710 bytes, checksum: 95bb8ae68a4f08995034c3d0cd52a3e7 (MD5) Previous issue date: 1993 / Resumo: Não informado / Abstract: Not informed. / Doutorado / Doutor em Filosofia

Thesis advisor: Richard M. Kearney / What is the relation between sex, death, and the divine? This question, which is of vital importance to Plato and which Freud tacitly takes up by turning to the Symposium at the end of Beyond the Pleasure Principle, can be seen as standing at the foundation of philosophy, theology, and psychoanalysis. It ought not to surprise us, then, to observe the vibrant conversation going on between Continental philosophers, theologians, and psychoanalysts today. This attempt to untangle and analyze the intersection where the “Heavenly Powers” of sex and death converge with the divine is that which allows Julia Kristeva to state, during a recent interview with Richard Kearney, that of all “the human sciences and the social sciences, the only rational approaches to human beings, psychoanalysis . . . come[s] closest . . . to the experience of faith.” It is that which enables Lacan to assert that “Saint Augustine . . . foreshadowed psychoanalysis” and to insist that psychoanalysts ought to “become versed in Augustine.” It is that which compels thinkers like Emmanuel Falque—who advise philosophers of religion to speak first and foremost about “finitude, the consciousness and horizon of death” —to write books on Freud and philosophy. And it is that which drives the work being undertaken today. The purpose of this dissertation is to approach once more the dark mystery of Eros and Thanatos which, to paraphrase Dostoevsky, forever struggle with God on the battlefield of the human heart. In order to broach this topic, I will attempt to establish a connection between carnal, bodily love and man’s relation to the divine. To do so, I will rely upon and further develop what Paul Ricoeur has called “the nuptial metaphor”—the recurring biblical motif that portrays God’s relation to man as a kind of love affair, neither reductively sexual nor legalistically marital, but passionate, romantic, protective, desirous, even jealous. Such an understanding of the connection between sexuality and spirituality is not without precedent. Consider, for example, the statement by Ignatius of Antioch from which this work derives its title—“my Eros has been crucified”—which Pseudo Dionysius reads as a supreme affirmation of divine desire. John Panteleimon Manoussakis, commenting on this link between the carnal and the spiritual, writes, “The desire for God is not independent from the desire for the other human . . . One who has not felt the latter rarely and with difficulty would seek the former.” I would add that, as Jean-Luc Marion argues in The Erotic Phenomenon, one who has felt the latter has perhaps already experienced the former, if only in a veiled way. Thus, where Freud reads the desire for God as a sublimation of the sex drives, I would suggest the opposite: erotic desire often reveals a deeper, more fundamental longing—a longing for the divine. And yet, Freud might counter, one must consider not only Eros but Thanatos. How does the desire for death factor into this religiously-inflected reading of the drives? That human sexuality implies both perversion and perfection, that it brings together man’s baseness and his beatitude, is one of the most important insights offered by Freudian drive theory. As Freud himself notes, “The highest and the lowest are always closest to each other in the sphere of sexuality.” But why this is the case remains for Freud a great mystery. Here, I would suggest, is where philosophy of religion can make an important contribution. Relying on the works of philosophers such as Manoussakis, Kearney, and Marion, theologians, in particular Hans Urs von Balthasar, and psychoanalysts such as Freud and Lacan, this work aims to both provide a possible answer to this fundamental question and to foster further dialogue between thinkers whose fields were born of similar concerns. / Thesis (PhD) — Boston College, 2019. / Submitted to: Boston College. Graduate School of Arts and Sciences. / Discipline: Philosophy.

Thesis advisor: Robert S. Lehman / This dissertation argues that literary modernism is structured by a logic of belatedness—its sense, that is, of having arrived too late. Belatedness thus perceived entails a reconsideration of late modernism, illuminated as it has been by scholars such as Jed Esty, Tyrus Miller, and C.D. Blanton. Because modernism is constituted first and foremost by its fraught relation to time, and, specifically, to the present and its representations, any discussion of late modernism must begin by interrogating the “afterlife” of this temporal predicament. Following Edward Said’s claim that modernism is a late-style phenomenon, Belated Modernism challenges the construct “late modernism” given that the notion of lateness is constitutive of modernism itself. This project necessitates a thinking beyond the generic, nationalistic, linguistic, and disciplinary distinctions that have informed most of the critical discourse on (Anglo-American) late modernism. To that end, Belated Modernism addresses a constellation of European writers whose late style emerges in modernism’s late phase: the strange parenthesis of 1939–1941, when the war had already begun but its magnitude was as yet unknowable. Focusing on the final works of Sigmund Freud (Moses and Monotheism [1939]), Walter Benjamin (“On the Concept of History” [1940]), and Virginia Woolf (Between the Acts [1941]), I argue that the singular conjunction of late style and late modernism reveals, in light of individual and world-historical ends, an intensification of the philosophical problem of belatedness that has haunted modernism since its origins. / Thesis (PhD) — Boston College, 2022. / Submitted to: Boston College. Graduate School of Arts and Sciences. / Discipline: English.

No description available.

<p>This study examines L.P. Hartley's male protagonists who provide the focus for his major fiction. The male characters' difficulties in understanding themselves, and the world which confronts them, are issues discussed by the few serious critics of Hartley's work. The book-length criticism, however, has tended to rely heavily upon figures like Freud and Jung, and upon Romantic and Judaeo-Christian thinking and symbolism, in order to establish its views. My study constitutes an attempt to avoid the overt application of "schools" to Hartley's work, although like Hartley himself I cannot claim to have been completely untainted, for example, by our Freudian climate. Specifically, I am interested in demonstrating the complex processes by which Hartley's sensitive male protagonists near self-understanding, and how Hartley uses detailed, even intricate, symbolism to express those developments.</p> <p>Using the Eustace and Hilda trilogy, I thoroughly examine Eustace Cherrington's growth toward self-understanding in order to demonstrate the special problems confronted by a typical Hartleian male. Leo Colston, in The Go-Between, and Stephen Leadbitter, in The Hireling, are then included in the discussion, and the three males' associations with fantasy worlds, and with manipulative women, are seen to contribute to the difficulties faced by these protagonists. In a final chapter, by examining the earlier fiction in the light of some of Hartley's less symbolic later novels, in particular The Harness Room, I indicate how Hartley's symbolism has been used, in the past, to conceal his interest in male homosexual relationships.</p> <p>Hartley, in addressing the issue of self-knowledge in his fiction, also makes a statement concerning the difficulty faced by the individual who, after the Second World War, was especially confronted with the task of securing an identity for himself in an increasingly egalitarian, fast-paced "modern" world. Hartley's canon is a metaphoric expression of how what Hartley terms the "Great Man" of Victorian fiction becomes the weak, victimised, but in many ways "greater" twentieth century man; for all his insecurity and failure, the Hartleian male of the 1970's is one who has painfully explored both himself and his environment in an attempt to survive, and to establish for himself, however temporarily, a "unique personality" appropriate to his time.</p> / Thesis / Doctor of Philosophy (PhD)

No description available.