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11	Factor structures of a Japanese version of the Geriatric Depression Scale and its correlation with the quality of life and functional ability. / 日本語版老年期うつ病尺度の因子構造とクオリティオブライフおよび日常生活機能との関連 Imai, Hissei 23 March 2015 (has links) 京都大学 / 0048 / 新制・課程博士 / 博士(医学) / 甲第18858号 / 医博第3969号 / 新制\|\|医\|\|1008(附属図書館) / 31809 / 京都大学大学院医学研究科医学専攻 / (主査)教授福原俊一, 教授古川壽亮, 教授村井俊哉 / 学位規則第4条第1項該当 / Doctor of Medical Science / Kyoto University / DFAM Depression Geriatric Depression Scale (GDS-15) Factor analysis Activities of daily living (ADL) Quality of life (QOL) 490
12	ADHD次分類型在認知功能與行為表現間的關係 / The relationship between cognitive function and behavior performance in ADHD subtypes 王淳弘 Unknown Date (has links) 本研究目的，在探討以行為症狀區分的ADHD次分類型，是否也能在認知功能上有其相對映的區辨？本研究以行為症狀量表DBRS，測量受試者在不專心注意與過動/易衝動向度上的行為症狀表現，以神經心理測驗GDS，測量受試者在不專心注意與過動/易衝動向度上的認知功能表現。本研究假設認為，以行為症狀量表DBRS所區辨出的不同ADHD次分類型，在神經心理測驗GDS上，應具有不同的認知功能表現模式。透過對63名6~9歲的男性學齡受試者，由行為症狀量表DBRS區分ADHD次分類型，並以單因子變異數分析及Pearson積差相關等方式，檢驗不同次分類型間在神經心理測驗GDS上的認知功能差異與關係。研究結果顯示，以DBRS所區分的次分類型，在GDS各相關認知功能指標上，都無法有效獲得顯著的差異與關係；大部分的測驗指標，皆未能有效支持本研究假設。研究結果顯示，在本研究樣本中，受試者母親在DBRS上填答的行為症狀表現，與受試者在神經心理測驗GDS上的認知功能表現，未能展現出一致及可茲對映的區辨能力。並在討論中針對此結果，提出可能的原因及相關的建議。 / The purpose of this study is to explore that if ADHD subtypes which are discriminated by behavioral symptoms could reflect the same discriminance on cognitive functions. In this study, the performance of inattention and hyperactive/impulsive behavioral symptoms are measured by the behavioral symptom scale, DBRS; and the performance of inattention and hyperactive/impulsive cognitive functions are measured by the neuropsychological testing, GDS. The hypotheses of this study are that the different ADHD subtypes which are measured by behavioral symptom scale, DBRS, should have different performance pattern of cognitive functions in GDS. This study sorts 63 male subjects, aged from 6 to 9 years old, into 4 subtypes and compares the differences by one way ANOVA and explores the relationships by Pearson product-moment correlation, so as to exam the cognitive differences and the relationships between subtypes on neuropsychological test, GDS. The results show that the subtypes which is discriminated by DBRS have no significant differences on most related cognitive-functioning indexes of GDS. Most testing indexes do not support the hypothese in this study. From the samples of this study the results show that the performance of behavioral symptoms on DBRS, based on mother's evaluation of subject's behavior, and subjects’ performance of cognitive functions on GDS do not have consistent or matched patern. The probabilistic explanation and related suggestion will be proposed in discussion. 次分類型認知功能行為表現 ADHD subtypes cognitive function behavioral performance GDS DBRS
13	Dementia, depression and delirium in the very old : prevalences and associated factors Mathillas, Johan January 2013 (has links) Emotional suffering in old age is largely caused by a variety of psychiatric disorders which are often, however, undertreated and underrecognized. This leads to reduced quality of life and functional status and increased morbidity and mortality. Dementia, delirium and depression are common disorders in the very old, and are similar in several ways. All have multiple causes and are diagnosed by means of symptomatic criteria, are challenging to diagnose and difficult to differentiate from each other in the very old. They often coexist in the same individual, and may have common risk factors. The overall aim of this thesis was to add to our knowledge about threats to successful aging, by investigating the prevalences of dementia, depression and delirium, and factors associated with these three disorders. Further aims were to measure change over time in the prevalence of dementia and depression, respectively, and to investigate the risk factors for incident depression. This thesis uses the population-based Umeå85+/GErontological Regional DAtabase (GERDA) material. In 2000-2002, every other 85-year-old, all 90-year-olds and all people ≥95 years living in six municipalities in Västerbotten, Sweden were invited to participate, and in 2005-2007 the process was repeated, with the additional inclusion of the corresponding populations of two municipalities in Österbotten, Finland. A third data collection was carried out in 2010-2012. Trained assessors carried out assessments in the form of structured interviews during one or more home visits, recorded current medication and reviewed medical records obtained from general practitioners and hospitals. In 2000-2002 the prevalence of dementia was 17% among 85-year-olds, 24% among 90-year-olds and 46% among those aged ≥95 years. In 2005-2007 dementia prevalence reached 28% among 85-year-olds, 40% among 90-yearolds and 45% among those aged ≥95 years. The prevalence of dementia in the total sample was 27% in 2000-2002 and 37% in 2005-2007 (p=0.001). In 2000-2002 the prevalence of depressive disorders was 24% among 85-yearolds, 34% among 90-year-olds and 31% among those aged ≥95 years. In 2005-2007 the prevalence of depressive disorders was 33% among 85-year-olds, 39% among 90-year-olds and 38% among those aged ≥95 years. The prevalence of depressive disorders in the total sample was 29% in 2000-2002 and 37% in 2005-2007 (p=0.025). Among participants not depressed at baseline, 26% had developed depression after five years. Factors independently associated with new cases of depression at follow-up were hypertension, a history of stroke and a higher score on the 15-item Geriatric Depression Scale at baseline. The thirtyday prevalence of delirium in 2005-2007 was 17% among 85-year-olds, 21% among 90-year-olds and 39% among participants aged ≥95 years. Delirium prevalence among individuals with dementia was higher than among those without dementia (52% vs. 5%, p<.001). Factors independently associated with delirium superimposed on dementia in a multivariate logistic regression model were depression, heart failure, living in an institution and prescribed antipsychotics. There was a high prevalence of dementia, depression and delirium in the papers comprising this thesis, and 55% had at least one of the three disorders. The prevalence of dementia and depression also increased between 2000-2002 and 2005-2007, after controlling for age and sex. Dementia and depression were important associated factors for delirium and half of those with dementia were depressed. The increasing age-specific prevalence of depression seems to be associated with the increasing age-specific prevalence of dementia. The papers presented are among the first to report a significantly increasing age-specific prevalence of dementia and depression among very old people. More knowledge about associated factors and risk factors concerning these disorders may be helpful for carers and decision-makers, as well as providing reference values for studies in other regions. Further efforts are needed in both care and research to better prevent, screen for, diagnose and treat dementia, depression and delirium, especially considering the growing number of very old people. / Umeå85+/GERDA dementia depression depressive disorders delirium aged 80 and over epidemiology cross-sectional study prevalence risk factors GDS-15 stroke hypertension
14	Exploratory Factor Analysis of the Geriatric Depression Scale Among Cardiac Patients Hupp, Gregory S. 05 1900 (has links) The Geriatric Depression Scale (GDS) was originally designed as a measure for screening depression among elderly medical patients. Although this instrument is well validated among a general medical population, it has never been evaluated with specific regard to cardiac patients, the largest single group of medical patients over 40 years of age. A general cardiac sample of 655 patients completed the GDS within 10 weeks of the cardiac event. Exploratory factor analyses were conducted on the main sample, then on several subgroups of participants with regard to diagnostic category, gender, and age. The GDS generally produces factor structures with several symptom domains with a high rate of total variance. The myocardial infarction group endorsed general symptoms of depression whereas the coronary artery bypass graft group reported greater levels of despair regarding their condition. Overall, males primarily reported agitation and hopelessness while females reported symptoms of depressed mood. Geriatic Depression Scale GDS Cardiac patients Elderly patients Psychological tests. Depression in old age. Older people -- Psychological testing.
15	Sintomatologia depressiva e avalia??o de n?veis de TNFα IL-2 em indiv?duos idosos e com doen?a pulmonar obstrutiva cr?nica Marinho, Patr?cia ?rika de Melo 09 October 2009 (has links) Made available in DSpace on 2014-12-17T14:13:33Z (GMT). No. of bitstreams: 1 PatriciaEMM_Tese.pdf: 847319 bytes, checksum: 45c87b0995e32e622482e82ba5c34d31 (MD5) Previous issue date: 2009-10-09 / The aim of the present study was to assess the presence of depressive symptomatology among elderly residents in long-stay institutions (LSI) and in the community of Recife, Brazil. In total, 81 long-stay elderly patients (mean age of 75.55 ? 9.18 years) and 132 elderly (mean age of 73.14 ? 8.27 years) individuals from the community were evaluated. Depressive symptomatology was assessed by the Geriatric Depression Scale (GDS-15), cognitive status by the Mini Mental State Examination (MMSE) and capacity to perform the activities of daily living (ADL) by the Katz Index. Comorbities and the use of medication were recorded. The LSI elderly exhibited more depressive symptoms (p < 0.001) and more dependency (p< 0.001). We observed no differences in MMSE (p = 0.058). The elderly in the community displayed more comorbidities and the LSI elderly consumed more medication (p < 0.001 and p < 0.001, respectively). According to multivariate analysis (logistic regression), being male, having no spouse and having a low schooling level are risk factors for depressive symptoms. In conclusion, most elderly with depressive symptoms received no medication fordepression. / Avaliar a preval?ncia de sintomas depressivos entre idosos e pacientes portadores de doen?a pulmonar obstrutiva cr?nica (DPOC) e suas rela??es com os n?veis de TNF-α e IL-2 e o horm?nio cortisol, comorbidades, consumo de medicamentos, composi??o corporal e desempenho no teste de caminhada de seis minutos (TC6min). Metodologia: Foram avaliados idosos e pacientes com DPOC quanto a presen?a de sintomas depressivos (GDS-15), cogni??o (MMSE), atividades de vida di?ria (AVD), composi??o corporal (Bioimped?ncia El?trica), TC6min, cortisol s?rico (Eletroquimioluminesc?ncia), TNF-α e IL-2 plasm?tico (Elisa). Resultados: Artigo 1. Os idosos das institui??es de longa perman?ncia (ILP) apresentaram mais sintomas depressivos, depend?ncia e maior consumo de medicamentos enquanto os da comunidade apresentaram mais comorbidades. Na an?lise multivariada, pertencer ao sexo masculino, n?o ter companheiro e ter baixa escolaridade se apresentaram como fatores de risco para a sintomatologia depressiva. Artigo 2.Os sintomas depressivos ocorreram em 22,5% dos pacientes com DPOC do sexo masculino. A deple??o muscular ocorreu a partir do n?vel leve de obstru??o entre aqueles sem sintomas e moderado entre aqueles com depress?o. A dist?ncia percorrida ficou abaixo do previsto e o tempo de caminhada com encorajamento foi maior no grupo sem sintomas. Artigo 3. A preval?ncia de sintomas depressivos foi maior no grupo dos pacientes DPOC. O n?mero de comorbidades foi maior entre aqueles com sintomas depressivos. N?o foram encontradas diferen?as quanto aos n?veis de TNF-α, IL-2, cortisol, n?mero de anos de fumo e ma?os-ano entre os grupos. O grupo DPOC apresentou maior freq??ncia de deple??o nutricional em rela??o aos idosos. Conclus?o: Os sintomas depressivos foram mais prevalentes entre idosos das ILP e com DPOC, e esses n?o foram acompanhados de tratamento com antidepressivos. N?o foram observadas diferen?as entre os n?veis de TNF-α, IL-2 e cortisol entre idosos da comunidade e com DPOC Sintomas depressivos Idosos DPOC Citocinas pr?inflamat?rias Depressive symptoms IOnstitutionalization Comorbidity GDS-15 MMSE Activities of daily living CNPQ::CIENCIAS DA SAUDE
16	Rozbor způsobu prodeje letenek a souvisejících služeb / Analysis of flight ticket distribution and related services Veselý, Martin January 2009 (has links) This diploma thesis analyzes distribution channels of flight tickets on the Internet and aspects related to this type of sale. Individual chapters deal with the historical background, role of e-commerce in the civil aviation industry, individual players engaged in the distribution of flight tickets on the Internet and the position of the online distribution. This thesis also analyzes modern services that are connected to the distribution of flight tickets, e.g. e-ticketing and new forms of check-in.
17	Současná role GDS na trhu distibuce služeb cestovního ruchu / The current role of GDS in the distribution market of tourist services Švejdová, Petra January 2011 (has links) Aviation industry is in many ways considered a pioneer, especially in innovation and implementation of new materials and technologies. The aim of this thesis is to provide comprehensive and complex information on the matter, pointing out the differences in distribution systems and scenarios outlining the expected evolution of these systems in the future. The dissertation defines the basic concepts and the nature of the problem and also talks about the historical development of the GDS to better understand the current ownership and evaluate the importance and status of GDS in the Czech and world market. It analyzes selected GDS and graphically illustrates the positions of the GDS on the certain markets within the category. The basic method used is the comparison which was done by putting the specifics of individual GDS and their subsequent comparison, the thesis also includes SWOT analysis.
18	Magnetotellurics and Geomagnetic Depth Sounding in Queensland, South Eastern Australia -Evidence for the Tasman Line? / Magnetotellurik und Geomagnetische Tiefensondierung in Queensland, Süd Ost-Australien -Nachweis für die Tasmanische Linie ? Fon, Lawrence Teku 30 September 2011 (has links) No description available. 530 Physik Physics Magnetotellurik GDS Tasmanische Linie MT-Übertragungsfunktion Schmucker s Perturbation-Tensor Küstenlinien-Effekt Induktions-Vektor Streich-Winkel Magnetotellurics GDS Tasman Line MT transfer functions Schmucker s Perturbation tensor Coast line effect Induction vector strike angle 3D modelling & Carpentaria anomaly. Physics RD
19	Artificial development of neural-symbolic networks Townsend, Joseph Paul January 2014 (has links) Artificial neural networks (ANNs) and logic programs have both been suggested as means of modelling human cognition. While ANNs are adaptable and relatively noise resistant, the information they represent is distributed across various neurons and is therefore difficult to interpret. On the contrary, symbolic systems such as logic programs are interpretable but less adaptable. Human cognition is performed in a network of biological neurons and yet is capable of representing symbols, and therefore an ideal model would combine the strengths of the two approaches. This is the goal of Neural-Symbolic Integration [4, 16, 21, 40], in which ANNs are used to produce interpretable, adaptable representations of logic programs and other symbolic models. One neural-symbolic model of reasoning is SHRUTI [89, 95], argued to exhibit biological plausibility in that it captures some aspects of real biological processes. SHRUTI's original developers also suggest that further biological plausibility can be ascribed to the fact that SHRUTI networks can be represented by a model of genetic development [96, 120]. The aims of this thesis are to support the claims of SHRUTI's developers by producing the first such genetic representation for SHRUTI networks and to explore biological plausibility further by investigating the evolvability of the proposed SHRUTI genome. The SHRUTI genome is developed and evolved using principles from Generative and Developmental Systems and Artificial Development [13, 105], in which genomes use indirect encoding to provide a set of instructions for the gradual development of the phenotype just as DNA does for biological organisms. This thesis presents genomes that develop SHRUTI representations of logical relations and episodic facts so that they are able to correctly answer questions on the knowledge they represent. The evolvability of the SHRUTI genomes is limited in that an evolutionary search was able to discover genomes for simple relational structures that did not include conjunction, but could not discover structures that enabled conjunctive relations or episodic facts to be learned. Experiments were performed to understand the SHRUTI fitness landscape and demonstrated that this landscape is unsuitable for navigation using an evolutionary search. Complex SHRUTI structures require that necessary substructures must be discovered in unison and not individually in order to yield a positive change in objective fitness that informs the evolutionary search of their discovery. The requirement for multiple substructures to be in place before fitness can be improved is probably owed to the localist representation of concepts and relations in SHRUTI. Therefore this thesis concludes by making a case for switching to more distributed representations as a possible means of improving evolvability in the future. 006.3
20	Byggvaruhuskedjors kravställningar på sina leverantörer En studie av bygghandeln i Sverige / DIY and building material retailers demands on their suppliers A study of the DIY and building material market in Sweden Fransson, Daniel January 2004 (has links) <p>Denna studie utreder vilka funktioner och roller som byggvaruhuskedjor efterfrågar att deras leverantörer från träindustrin bör ha i marknadskanalen. Vidare förklaras hur dessa leverantörer bör agera för att möta dessa krav och förväntningar. Sålunda skapas gynnsamma utvecklingsmöjligheter av nya produktlösningar för att svara upp till nya krav på teknik och produktutveckling för att öka försäljningen av trävaror till de viktiga GDS (Gör-Det-Själv)- och byggmaterialmarknaderna i både Sverige och Europa. Byggvaruhuskedjorna anser att träindustrin har ett alldeles för stort produktions- och volymfokus och inriktar sig för mycket på export av trävaror. Byggvaruhuskedjor efterfrågar alltmer en leverantör från träindustrin med en hög anpassningsförmåga som kan medverka i kedjans utvecklingsarbete och som samtidigt har stor lyhördhet gentemot marknadens behov och har möjlighet att göra anpassningar till lokala GDS- och byggmaterialmarknader. Leverantörer från träindustrin måste sålunda gå ifrån produktions- och volymfokusering till kundutveckling och kundfokus. Deras produktivitetsutveckling och samarbetsvillighet har en stor betydelse för att generera en välfungerande interaktion med sina kunder. Sålunda kan en koppling mellan deras egen produktion och deras kunders behov utvecklas. Det kommer sannolikt att bli mycket kostsamt och svårt för träindustrin att försöka bearbeta den svenska och europeiska marknaderna utan att använda byggvaruhuskedjorna som marknadskanal. Byggvaruhuskedjornas ökade konsumentfokus och riktade marknadsföring medför enligt dem själva en expansion av marknaden samtidigt som prismedvetenheten och kraven från GDS- och byggmaterialmarknaderna ökar. Byggvaruhuskedjorna verkar alltmer fungera som systemintegratör och anser själva att de känner av en större makt gentemot sina leverantörer. Byggvaruhuskedjorna förefaller dock svårare att definiera som antigen mega-retailers eller category-killers. Branschgränserna blir alltmer oklara och det blir sålunda svårare att avgöra vilka företag som specifikt kan klassificeras att tillhöra bygghandeln Den nationella bygghandeln blir samtidigt alltmer internationell och sammanfattningsvis verkar en marknadskanal med nya funktioner och strukturer att utvecklas.</p> Business and economics marknadskanaler strategisk utveckling värdekedjor industriell försäljning vertikal integration industriella nätverk interaktion bindningar industriella inköpsprocesser återförsäljarkedjor träindustrin bygghandeln byggvaruhuskedjor byggmaterial gör det själv marknaden GDS-marknaden dynamisk industriell miljö strukturella förändringar leverantörsrelationer byggsystem affärsutveckling trävaror systemförsäljning systemintegratör Bauhaus Beijer Byggmaterial Byggtrygg Coop Hornbach Interpares K-Rauta Optimera market channels marketing channels strategic development mega-retailers category-killers value chains industrial networks interaction purchase processes retailers forest industry supplier relations building systems business development supplier development do it yourself DIY-retailers building material building merchant wood products system integrator system sales. Ekonomi Business and economics Ekonomi

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