本篇研究試圖探討半導體產業供應鏈上游的IC設計業者召開法人說明會後，基於我國半導體產業供應鏈緊密連結之特性，同屬半導體供應鏈的其他中、下游製造和封測廠之機構投資人的交易行為是否將受到IC設計業者宣告之法人說明會資訊影響，亦即證明法人說明會資訊在半導體供應鏈中是否具有垂直資訊移轉效果。實證結果發現在法人說明會召開訊息首次見報日時，供應鏈上游公司之法人說明會訊息確實會影響其中、下游公司之機構投資人的持股變化，於宣告好(壞)消息時買進(賣出)，顯示機構投資人藉由其專業團隊和私有資訊能早一般大眾提前調整其交易策略，而此資訊移轉效果也會隨著公司在供應鏈上之距離而逐漸稀釋。此外，結果亦顯示外資由於地緣限制，相較於投信和自營商更會倚賴法人說明會宣告之資訊調整其持股策略，於宣告好(壞)消息時買進(賣出)。 / This research examine the conference call which hold by the IC design companies will transfer useful information to the institutional investors of IC manufacturing and packaging companies in the supply chain downstream. I am interested in if there is a vertical information transfer in the semi-conduct industry. The empirical results show that the conference call information is significantly influence the holding percentage of the institutional investors of the downstream supply chain companies after the information of conference call first reported in the newspapers. The institutional investors will increase the holding percentage after the good news released and vice versa. It is showed that the institutional investors can gather more information before the conference call and adjust their invest strategy in advance. Furthermore, this vertical information transfer effect will dilute by degrees as distance increases. Lastly, the result also shows that the foreign institutional investors more rely on the information released from the conference call to adjust their invest strategy than native institutional investors.

Business processes that are maintained in, and through, digital information chains are a widespread phenomenon in society. In these chains, several actors are active both in the production and transfer of information, where each actor is dependent on another actor's effective transmission to be able to perform his job. To explore this phenomenon, this study investigates an electronic referral process of the regional Health Care system in Sweden, that allows for the transfer of rights, duties and obligations between health care providers. In this process, effective information transfer is necessary to achieve high levels of patient safety and to prevent delays in care delivery. This study intends to unveil the technological and communicative challenges of information transfer faced by doctors who are involved in that process. The study draws upon primary data collected from nine interviews conducted with secondary care doctors working at the Uppsala University Hospital. The results were analyzed primarily using communication theories of representation and through a constructionist perspective of knowledge. The results show that most challenges are communicative, most of which, as well as the technological challenges identified, relate to mediation and sharing of meaning. Challenges also tend to be more or less prominent depending on the actors involved, and the nature of what is being transferred. In order to deal with the challenges, the referral process is circumvented and the methods of circumventing prove to be as institutionalized as the referral process itself. / Verksamhetsprocesser som upprätthålls i och genom digitala informationskedjor är ett utbrett fenomen. I dessa kedjor är flertalet aktörer aktiva i både produktionen och överföringen av information, där varje aktör är beroende av en annan aktörs överföring för att kunna utföra sitt arbete. I avsikt att närma sig detta fenomen, är syftet med studien att förstå vilka utmaningar som kan uppstå i en sådan verksamhetsprocess genom att undersöka det digitala remissförfarandet inom sjukvården. Remissförfarandet är en central process genom vilken patientvård samordnas via remisser och remissvar. För att uppnå hög patientsäkerhet, är processen beroende av effektiv informationsöverföring. Frågeställningen som studien ämnar besvara, är “Vilka informationsteknologiska och kommunikativa utmaningar kring informationsöverföring i remissförfarandet upplevs inom specialistsjukvården?”. För att besvara denna fråga har nio intervjuer med specialistläkare på Akademiska sjukhuset i Uppsala utförts. Intervjudatan har i huvudsak analyserats utifrån ett kommunikationsvetenskapligt angreppssätt som kombinerar ett konstruktivistiskt kunskapsperspektiv och representationsteori. Resultaten visar på att majoriteten av utmaningar är kommunikativa, varav de flesta, liksom de informationsteknologiska utmaningar som identifierats, relaterar till förmedling och delande av mening. Utmaningar tenderar också bli mer eller mindre framträdande beroende på vilka aktörer som deltar i informationskedjan samt karaktären på det som överförs. För att hantera utmaningarna kringgås remissförfarandet, där sätten att kringgå visar sig vara lika institutionaliserat som remissförfarandet självt.

La integración de las Tecnologías de la Información y Comunicación (TIC) a inicios del 2020 se han visto utilizadas con mayor frecuencia en la educación superior del Perú. Este aceleramiento ha sido causado por la pandemia del COVID-19 en el país. Por lo cual, ha permitido facilitar la comunicación y percepción de la información entre docente y discente. Ahora, existen diversas herramientas que ayudan a los usuarios a ser autónomos y aprender de manera sincrónica y asincrónica. Es por ello, que esta investigación tiene como objetivo general analizar los modos de interacción entre docente y discente mediados por las TIC en  el curso de Empresas Audiovisuales y Gestión Cultural en la carrera de Comunicación Audiovisual y Medios Interactivos de la UPC. La metodología empleada es el paradigma interpretativo y enfoque cualitativo. Para la presente investigación se contó con la participación de un grupo de docentes de la UPC y un grupo de expertos relacionados a la integración de las TIC en educación superior. También se tomó como muestra a un grupo de estudiantes para comprender cómo emplean las TIC a lo largo de sus estudios. A la muestra mencionada se le realizará entrevistas y observación participante de forma digital para enriquecer el estudio y obtener un acercamiento a la realidad que viven los alumnos como los docentes. / The integration of Information and Communication Technologies (ICT) in early 2020 have been used more frequently in higher education in Peru. This acceleration has been created by the COVID-19 pandemic in the country. Therefore, it has facilitated communication and perception of information between teacher and student. Now, there are various tools that help users to be autonomous and learn synchronously and asynchronously. That is why this research aims to analyze the modes of interaction between teacher and student mediated by ICT in the Audiovisual Business and Cultural Management course in the Audiovisual Communication and Interactive Media career at the UPC. The methodology used is the interpretive paradigm and qualitative approach. For this research, a group of teachers from the UPC and a group of experts related to the integration of ICT in higher education participated. A group of students was also sampled to understand how they use ICT throughout their studies. The aforementioned sample will be given presentations and participant observation in a digital way to enrich the study and obtain an approach to the reality that students and teachers experience. / Trabajo de investigación

Discipline récente, la chimie supramoléculaire est l'un des domaines les plus fertiles de la recherche chimique. Motivé par le défi que représente la reconnaissance moléculaire sur mesure d'édifices complexes, un grand intérêt est apparu pour la conception et la synthèse des récepteurs macrocycliques polyfonctionnalisés. Nous avons récemment décrit une nouvelle classe de récepteurs moléculaires accessibles et polyvalents: les Dyn[n]arenes. Cette nouvelle classe est obtenue à partir de briques moléculaires 1,4-dithiophénols fonctionnalisés en position ortho assemblées par des liaisons disulfures. Cette stratégie de macrocyclisation contrôlée thermodynamiquement permet de produire de grandes quantités de produit final avec un moindre coût synthétique. Des récepteurs sur-mesure pour la reconnaissance d'anions, de cations et de zwitterions ont été obtenus par cette approche polyvalente. En particulier, le Dyn[4]arene octacarboxylate a montré la capacité de reconnaître sélectivement des dérivés de la lysine par via un ajustement induit asymétrique du récepteur lors de l'association. L'utilisation de ce récepteur pour reconnaître des peptides et protéines portant en position N-terminale une lysine a été étudiée. Enfin, la post-fonctionnalisation de ces Dyn[4]arenes a été explorée afin d'améliorer leur solubilité et leur propriétés de reconnaissance vis-à-vis de cibles biologiquement actives, ainsi que pour étudier la possibilité de leur greffage sur phase solide et leur utilisation en chromatographie d'affinité / As a recent discipline, supramolecular chemistry is one of the most active and fast-growing fields of chemical research. Driven by the challenge that tailored molecular recognition of complex molecules represents, a large interest has grown for the design and synthesis of multi-functionalized macrocyclic receptors. We recently described a new class of accessible and versatile molecular receptors: Dyn[n]arenes. This new class is obtained from 1,4-dithiophenols units functionalized in ortho position and assembled by disulfide linkages. This strategy of thermodynamically controlled macrocyclization allows producing large amounts of final product with a low synthetic cost. On demand receptors for anions, cations and zwitterions were obtained by this versatile approach. Particularly, the octacarboxylate-bearing dyn[4]arene showed the ability to selectively recognize Lysine derivatives via an asymmetric induced adjustment of the receptor upon the complexation. The use of this receptor to recognize N-terminal Lysine tagged peptides and proteins have been investigated. Finally, post-functionalization of Dyn[4]arenes have been explored to improve their solubility and recognition properties toward biologically active target and to investigate their solid phase grafting to be implemented in affinity chromatography

本研究主要探討台灣半導體產業供應鏈上游公司召開法人說明會是否會影響中下游公司之股價。本研究將法人說明會公布之資訊區分為財務資訊及非財務資訊，除探討財務資訊對供應鏈中、下游公司股價是否具影響效果外，亦探討財務及非財務的法人說明會資訊是否具有增額效果。實證結果顯示財務資訊在法人說明會召開前後一天與累積異常報酬呈現顯著正向關係，但非財務資訊卻呈現顯著反向關係，顯示非財務資訊會修正財務資訊所造成之效果。另外，資訊於供應鏈中移轉之距離越長，則移轉效果會越小，但若單純為好消息或壞消息，則移轉效果將增強。 / This research examines the influence of conference call information on the stock price of supply chain partners. The semi-conductor industries in Taiwan were used in this paper to examine the issue. I examined two kinds of information disclosed from conference calls: financial information and non-financial information. I first examined the information contained in conference calls for any effects on supply chain partners. Furthermore, I also examined to see if the non-financial information contains any additional effects to the supply chain partners. The empirical results show that the accumulated abnormal return of the supply chain partners is significantly positive related to the financial information around the conference call date. The accumulated abnormal return of the supply chain partners is significantly negative related to the non-financial information around the conference call date. The results show that both financial and non-financial information would influence the accumulated abnormal return of supply chain partners. The non-financial information contains additional information that revises the influence of the financial information.

Chimie dynamique: reconnaissance de nucléobases par des récepteurs synthétiques et isomérie cis-trans d'hydrazones acylées.Ce travail traite du développement des systèmes moléculaires qui peuvent s'adapter à l'addition de substances qui agissent comme un gabarit. Cette approche permet d'isoler une espèce majeure à partir d'un mélange de composés par le biais de la chimie combinatoire dynamique (CCD). La première partie de ma thèse de doctorat inclus l'utilisation d'un ADN simple brin (ADNsb) comme un gabarit pour le transfert d'information par auto-assemblage de récepteurs sans avoir besoin d'enzyme. De nouveaux récepteurs de l'adénine et de la guanine (pinces A et G) solubles dans l'eau ont été conçues dans ce but. Une approche utilisant la résonance magnétique nucléaire (RMN) a été utilisée pour déterminer l'affinité de liaison comme preuve d'une reconnaissance spécifique et efficace. Une évaluation dans l'eau par dichroïsme circulaire (CD) et mesure de la température de fusion par UV (Tm) a été réalisée. Cela a permis de tester respectivement la capacité d'auto-assemblage entre les pinces et un modèle ADNsb, et la force du processus de coopérativité. La deuxième partie de ce travail est axée sur le tri spontanné de motifs pyridine acylhydrazone et sur les configurations intéressantes qu'ils adoptent. Nous avons étudié la synthèse d'une série de motifs pyridine acylhydrazone: dimère, trimères et pentamères. Des études RMN ont permis d'évaluer les changements dans l'équilibre configurationnel cis / trans de ces systèmes dynamiques. Les études ont montré que l'équilibre attendu est biaise la cis acylhydrazone pyridine isomère a été observée par diffraction des rayons X. / Dynamic chemistry: nucleobase recognition by synthetic receptors and cis-trans acylhydrazone isomerism. This work deals with the development of molecular systems which can adapt upon the addition of substances that act as templates. This approach enables one major species to be identified from a mixture of compounds through the use of dynamic combinatorial chemistry (DCC). The first part of my PhD included the use of a single stranded DNA (ssDNA) as a template for information transfer via the self-assembly of receptors without the need for enzymes. New water soluble adenine and guanine receptors (A and G clamps) were designed and synthesised for this purpose. Nuclear magnetic resonance (NMR) titration studies were carried out to calculate the binding affinity and as a proof of specific and efficient recognition. An assessment in water via circular dichroism (CD) and UV temperature melting (Tm) studies was carried out. This tested the ability for self-assembly between the clamps and a ssDNA template and the strength of the cooperative process respectively. The second part of my PhD focused on the self-sorting of acylhydrazone pyridine motifs and the interesting configurations they adopt. The feasibility to synthesise these acylhydrazone pyridine motifs (dimer, trimers and pentamers) was investigated. X-ray and NMR studies showed that the equilibrium was found to be biased in an unusual way, and the cis acylhydrazone pyridine isomer was observed.