This dissertation thesis summarizes results of experiments that have been carried out during my PhD studies related to the new mass spectrometric methods for trace gas analysis of human breath. The thesis is divided into the theoretical and experimental part. The chapter at the beginning of this dissertation summarizes the current research in the area of breath analysis. It is describing the common breath metabolites, benefits and challenges of the method for therapeutic monitoring and clinical diagnosis and current applications. The next chapter of the theoretical introduction describes the techniques suitable for this area of research, with a special emphasis on mass-spectrometric techniques (in particular the selected ion flow tube mass spectrometry, SIFT-MS, method that allows accurate quantification of trace gases and vapours in humid air/human breath). All these parts are elaborated via the scientific literature review. The following chapters are then directly related to my own research and describes the conducted experiment, including the results obtained. This experimental part "Results and Discussion" is divided to the individual subsections, which are conceived as the commentaries to the enclosed research papers published in peer reviewed journals. The first is the detailed step by step...

The question of how ions interact with each other and with the potential energy barrier in thin lipid bilayer membranes has interested investigators for several years. The application of electrodiffusion theory to the study of this question is the central theme of this work. We have calculated current-voltage curves for barriers of various shapes and heights, in each case by means of numerically integrating the exact electrodiffusion equation as well as this same equation in the constant field approximation. We have also calculated the total charge in the membrane for the same conditions under which we have calculated the current-voltage curves.

京都大学 / 0048 / 新制・課程博士 / 博士(エネルギー科学) / 甲第19333号 / エネ博第322号 / 新制||エネ||65(附属図書館) / 32335 / 京都大学大学院エネルギー科学研究科エネルギー基礎科学専攻 / (主査)教授 中村 祐司, 教授 岸本 泰明, 教授 水内 亨 / 学位規則第4条第1項該当 / Doctor of Energy Science / Kyoto University / DGAM

京都大学 / 新制・論文博士 / 博士(医学) / 乙第13579号 / 論医博第2301号 / 新制||医||1069(附属図書館) / 京都大学大学院医学研究科医学専攻 / (主査)教授 古川 壽亮, 教授 大鶴 繁, 教授 平井 豊博 / 学位規則第4条第2項該当 / Doctor of Medical Science / Kyoto University / DFAM

No description available.

京都大学 / 新制・課程博士 / 博士(工学) / 甲第23883号 / 工博第4970号 / 新制||工||1776(附属図書館) / 京都大学大学院工学研究科機械理工学専攻 / (主査)教授 蓮尾 昌裕, 教授 鈴木 基史, 教授 江利口 浩二 / 学位規則第4条第1項該当 / Doctor of Philosophy (Engineering) / Kyoto University / DFAM

No description available.

No description available.