Orientador: Ketty Abaroa de Rezende / Tese (doutorado) - Universidade Estadual de Campinas, Instituto de Matemática, Estatística e Computação Científica / Made available in DSpace on 2018-08-16T08:12:09Z (GMT). No. of bitstreams: 1 MontufarLopez_HernanRoberto_D.pdf: 8015438 bytes, checksum: 1175f8d0f78fe476b09178b6e50f10ec (MD5) Previous issue date: 2010 / Resumo: Em [6] são apresentadas condições necessárias e suficientes para a estabilidade estrutural e o teorema de densidade para campos de vetores em 2-variedades com singularidades simples dos seguintes tipos: cone, guarda-chuva de Whitney, ponto duplo e ponto triplo. Nesta tese, estudamos os fluxos induzidos por estes campos de vetores, que denominamos fluxos Gutierrez-Sotomayor, do ponto de vista topológico utilizando a teoria de Conley. Apresentamos uma fórmula dinâmico-topológica que relaciona o índice de Conley de uma variedade com singularidades simples M que possui uma estratificação que a decompõe numa união disjunta da sua parte regular e da sua parte singular. Usando essa estratificação mostramos que se a singularidade está na parte singular S de M o seu índice pode ser calculado tanto com respeito a M como com respeito a S. Definimos uma função de Lyapunov, neste contexto, e mostramos sua existência para fluxos sem órbitas periódicas e sem ciclos singulares. Em seguida, por uma análise da seqüência de homologia longa exata de um par índice determinamos propriedades que um grafo de Lyapunov deve satisfazer para estar associado a um fluxo. Também abordamos a questão da realização de grafos de Lyapunov abstratos. Para isto, primeiramente apresentamos a igualdade de Poincaré-Hopf, para o caso bidimensional, que caracteriza a relação entre o primeiro número de Betti das 1-variedades ramificadas que são fronteiras de um bloco isolante com seu número de componentes de fronteira e o índice numérico de Conley. Em seguida, mostramos que dados números inteiros positivos que satisfaçam a condição de Poincaré-Hopf sempre é possível construir um bloco isolante que satisfaz estes dados dinâmicos e homológicos / Abstract: In [6] a characterization and genericity theorem for C1-structurally stable vector fields tangent to a 2-dimensional compact subset M of Rk are established. Also in [6], new types of structurally stable singularities and periodic orbits are presented. In this thesis we study the continuous flows associated to these vector fields, which we refer to as the Gutierrez-Sotomayor flows on manifolds M with simple singularities using Conley Index Theory. We consider a stratification of M which decomposes it into a union of its regular and singular strata. We prove certain Euler type formulas which relate topology of M and dynamics on the singular strata. We show the existence of a Lyapunov function for Gutierrez-Sotomayor flows without periodic orbits and singular cycles in this context. Using long exact sequence analysis of index pairs we determine necessary and sufficient conditions for a Gutierrez-Sotomayor flow to be defined on an isolating block. We organize this combinatorially with the aid of Lyapunov graphs and using a Poincar'e-Hopf equality we give necessary conditions for a Lyapunov graph to be associated to a Gutierrez-Sotomayor flow and we also prove these conditions are sufficient / Doutorado / Geometria e Topologia / Doutor em Matemática

<p> Cell encapsulation aims at the delivery of a therapeutic protein to a patient from transplanted cells. Conventional approaches involve immune-isolating cell lines that have been genetically modified to express a therapeutic protein, in alginate-based microcapsules. The long-term success of this approach hinges on the structural stability of the microcapsules, as well as their ability to maintain an environment suitable for the long-term survival of encapsulated cells. The most commonly studied type of microcapsule is the alginate-poly-Llysine-alginate (APA) microcapsule. However, the main concern with AP A microcapsules is the Joss of structural integrity during long-term implantation due to the exchange of calcium ions with other physiological ions, as well as the loss of the polyelectrolyte overcoats. </p> <p> In order to increase the structural stability of the microcapsules, we developed and characterized a number of synthetic polyelectrolytes that undergo phase separation upon complexation, and which are capable of forming covalent cross-links. These reactive polyelectrolytes are designed to take the place of poly-L-lysine and the outer alginate layer. We also explored combining cross-linkable synthetic polyanions with sodium alginate to strengthen the Ca Alginate core, by forming a core cross-linked network extending throughout the microcapsules. The polyelectrolyte complexes, encapsulation processes and microcapsule properties were studied in detail using extensive characterization techniques, including collaborative work on cell viability and host-immune response. </p> <p> Overall, this thesis describes a novel approach and prom1smg materials for cell encapsulations that offer enhanced microcapsule resistance to chemical and mechanical stresses, while preserving the desired biocompatibility. These materials may ultimately be useful for clinical immunosuppressive therapies. </p> / Thesis / Doctor of Philosophy (PhD)

1 TITLE: Sino-Korean Lexicon in Modern Korean AUTHOR: Vladislava Mazana DEPARTMENT: Institute of East Asian Studies SUPERVISOR: Mgr. Tomáš Horák, Ph.D. ABSTRACT: This diploma paper is focused on morphological aspects of the Sino-Korean lexicon in modern Korean, the main topics are Sino-Korean word-formation and Sino-Korean classification of parts of speech. Hereby considered are the typological differences between Korean, an agglutinative language and Chinese, an isolative-polysyntetic language. The problem with Sino-Korean words is their ambiguity and vagueness, they appear in various grammatical and syntactical functions with their form unchanged. One morpheme can simultaneously function as an affix and root. This paper analyzes forms of function units, it deals with ways of word-formation (composition and derivation). The ways of prefixation and suffixation are researched. Based on the results of this analysis an adequate classification of Sino-Korean parts of speech is aimed to be established. Both the original Korean and the Chinese systems of parts of speech are taken into account but neither of them corresponds with the characterics and functions of the Sino-Korean words. Considering the multifunctional character of Sino-Korean morphemes it is extremely difficult to classify the words into parts of...

Made available in DSpace on 2014-12-17T14:58:22Z (GMT). No. of bitstreams: 1 JoaoAAB_DISSERT.pdf: 2621016 bytes, checksum: 39aa654f0df748b1db86062c61ed8f35 (MD5) Previous issue date: 2013-05-16 / Emerald mining is an important area of the economy in Brazil, country which is in second place among the exporting nations of this gem. Due to the process of extraction, a great amount of reject is generated. Since there is no appropriate destination, the reject is abandoned around the mining industries, contributing to environment degradation. Nowadays, some of the most relevant things to an industry in general are: energy conservation, cost reduction, quality and productivity enhancement. The production of isolating, transformed refractory materials achieves the sustainability dimension when protection of the environment is incorporated to such process. This work investigates the use of emerald mining rejects in the ceramic body of refractory materials, aiming at obtaining a product whose characteristics are compatible with commercial products and, at the same time, allow the use of such rejects to solve the environmental issue caused by its disposal in nature. X-ray fluorescence analysis show that the emerald reject obtained after the flotation to extract molybdenum and mica has 70% of silica and alumina (SiO2+Al2O3) and 21% of a basic oxides and alkaline metals and earthy alkaline mixture (Na2O, K2O, CaO e MgO). Because of the significant amount of silica and alumina present in the reject, four refractory ceramic bodies were prepared. Samples with a rectangular shape and dimensions 100x50x10 mm were pressed in a steel mold at 27,5 MPa and sintered at 1200?C for 40 min. under environment atmosphere in a resistive oven. The sintered samples were characterized in relation to the chemical composition (FRX), mineralogical composition (DRX), microstructure (MEV) and physical and mechanical properties. The results indicate that the mixture with 45% of reject, 45% of alumina and 10% of kaolin presents a refractory quality of 1420?C, dimensional linear variation below 2.00%, apparent specific mass of 1,56 g/cm3 and porosity of 46,68%, which demonstrates the potential use of the reject as raw material for the industry of isolating transformed refractory materials / A minera??o de esmeraldas ? uma importante ?rea da atividade econ?mica do Brasil, pa?s que ocupa o segundo lugar entre as na??es exportadoras dessa gema. Em virtude do processo de extra??o, uma grande quantidade de rejeito ? gerada. Como n?o h? uma destina??o apropriada, o rejeito ? abandonado ao redor das mineradoras, contribuindo, assim, para a degrada??o do meio ambiente. Atualmente, alguns dos pontos de maior relev?ncia para a ind?stria em geral s?o: conserva??o de energia, redu??o de custos, melhoria de qualidade e produtividade. A produ??o de refrat?rios conformados isolantes ganha a dimens?o de sustentabilidade quando a prote??o ao meio ambiente ? incorporada a tal processo. Este trabalho investiga o uso de rejeitos da minera??o de esmeraldas na massa cer?mica de materiais refrat?rios, com intuito de obter um produto com caracter?sticas compat?veis aos produtos comerciais e, ao mesmo tempo, viabilizar a utiliza??o de tais rejeitos para solucionar o problema ambiental gerado por seu descarte na natureza. An?lises de fluoresc?ncia de raios x mostram que o rejeito de esmeraldas obtido ap?s a flota??o para retirada de molibd?nio e mica possui 70% de s?lica e alumina (SiO2+Al2O3) e 21% de uma mistura de ?xidos b?sicos de metais alcalinos e alcalinos terrosos (Na2O, K2O, CaO e MgO). Em fun??o dos significativos teores de s?lica e de alumina presentes no rejeito, quatro massas cer?micas refrat?rias foram preparadas. Corpos de prova com forma retangular e dimens?es 100x50x10 mm foram prensados em uma matriz de a?o a 27,5 MPa e sinterizados a 1200?C por 40 min. sob atmosfera ambiente em forno resistivo. Os corpos de prova sinterizados foram caracterizados com rela??o ? composi??o qu?mica (FRX), composi??o mineral?gica (DRX), microestrutura (MEV) e propriedades f?sicas e mec?nicas. Os resultados obtidos indicam que a mistura com 45% de rejeito, 45% de alumina e 10% de caulim apresenta uma refratariedade de 1420?C, varia??o linear dimensional inferior a 2,00%, densidade de massa aparente de 1,56 g/cm3 e porosidade total de 46,68%. Isto demonstra que o rejeito possui um potencial como mat?ria-prima para aplica??o na ind?stria de materiais refrat?rios conformados isolante

When species compete for resources, in a stable homogeneous environment, there are two possible outcomes. The first is that one species will out-compete the other and exclude it from the environment. This is known as the competitive exclusion principle. The second is that both species will manage to coexist. Coexistence can only occur if the species’ niches are differentiated such that interspecific competition is minimised, or eliminated. This outcome is known as resource partitioning. Two closely related Australian skink species of the Egernia genus, Egernia multiscutata and Egernia whitii, are abundant and sympatric on Wedge Island in South Australia’s Spencer Gulf. The species are morphologically very similar and appear to have very similar life histories and habitat requirements. Ostensibly, they would compete for limiting resources in this environment. This thesis is the first investigation into resource partitioning in this previously unstudied model organism. I report the results of multi-faceted investigations into the coexistence of the skinks, E. multiscutata and E. whitii on Wedge Island and the evidence for, and mechanisms of, any facultative resource partitioning between them. Study methods involved a transect survey of most of Wedge Island to determine the species’ distributions and any evidence for resource partitioning; a morphological comparison to investigate any potential competitive advantages of either species; a habitat choice experiment to establish retreat-site preferences in the absence of interspecific interference; and, a series of staged dyadic encounter experiments to investigate interspecific competitive interactions. Resource partitioning was evidenced by differential distributions of the species among substrates containing the elements required for permanent refuge shelters. This partitioning was not mediated by avoidance of particular substrates but by the presence of the opponent species, combined with attraction to suitable substrates. Asymmetries in some morphological characters were found to confer a potential competitive advantage to E. multiscutata in agonistic encounters with E. whitii. Both species were found to have the same refuge site preferences when interference competition was experimentally removed. This result was not concordant with observed resource partitioning in the field and suggests that the habitat choices of both species are modified by the presence of the opponent species. Analyses of staged dyadic encounter experiments showed that E. multiscutata was more likely to gain greater access to a contested habitat resource and more likely to exclude E. whitii from the resource than vice-versa. Nevertheless, the outcome of competitive interactions was not completely deterministic and there was some tolerance of co-habitation. E. multiscutata’s competitive advantage was attributable largely to its greater mass and head dimensions relative to snout to vent length. However, differential behavioural responses to the threat of larger opponent size also played an important part in resource partitioning between the species.

Habitat loss and fragmentation is a crisis affecting wildlife worldwide. In Tanzania, East Africa, a dramatic and recent (<80 years) expansion in human settlement and agriculture threatens to reduce gene flow among protected areas for many species of large mammals. Wildlife linkages can mitigate population isolation, but linkage designs lacking empirical justification may be controversial and ineffective. Connectivity conservation requires an understanding of how biogeographic factors shaped gene flow prior to habitat loss or fragmentation, however the history of interaction among populations is rarely known. The goal of my study was to provide context for connectivity conservation in central and southern Tanzania by identifying landscape features that have shaped gene flow for three ungulate species with different dispersal capabilities. I investigated historical patterns of connectivity for Maasai giraffe (Giraffa camelopardalis tippelskirchi), impala (Aepyceros melampus), and eland (Tragelaphus oryx) by estimating genetic structure among four to eight protected areas per species. Genetic structure changes very slowly among large populations and thus is likely to reflect historical processes instead of recent anthropogenic influences. I collected noninvasive DNA samples and generated microsatellite genotypes at 8 to 15 loci per species, then estimated genetic diversity metrics (allelic richness, AR, and expected heterozygosity, H[subscript E]) for each population (defined by reserve). I also calculated genetic distance (F[subscript ST] and Nei's unbiased genetic distance, D[subscript hat]) and an estimate of gene flow (Nm) between all population pairs for each species. To elucidate the possible causes of genetic structure between these populations, I tested for isolation by distance and isolation by resistance based on a suite of biogeographic factors hypothesized to affect gene flow. To do this, I created GIS-based resistance surfaces that assigned different costs of movement to landscape features. I created one or more resistance surfaces for each hypothesis of landscape effect. I used circuit theory to estimate the cumulative resistance between each pair of reserves for each weighting scheme, and then performed Mantel tests to calculate the correlation between these resistances and the observed population pairwise genetic distances (D[subscript hat]). I chose the optimal resistance model for each species as the model that was most highly correlated with observed genetic patterns. To verify that the correlation of resistance models with genetic distance was not an artefact of geographic distance, I performed partial Mantel tests to calculate correlation while controlling for the effect of geographic distance. Finally, I compared historical gene flow patterns to the distribution of contemporary human activity to predict areas that are at risk of a loss of connectivity. Indices of genetic diversity were moderate for all three species and comparable to previously reported values for other savannah ungulates. Diversity (both H[subscript E] and A[subscript R]) was highest in eland and lowest in giraffe for these populations, and was not consistently correlated with reserve size as has been reported for other species in East Africa. Although patterns in genetic distance were broadly similar across all three species there were also striking differences in connectivity, highlighting the importance of cross-species comparisons in connectivity conservation. At this scale, resistance models based on slope strongly predicted population structure for all three species; distance to water was also highly correlated with genetic distance in eland. For all three species, the greatest genetic distances occurred between populations separated by the Eastern Arc Mountains, suggesting that the topography of this area has long acted as a barrier to gene flow, but this effect is present in varying degrees for each species. I observed high levels of historical gene flow between centrally located populations (Ruaha National Park and Rungwa Game Reserve) and those in the southwest (Katavi National Park and Rukwa Game Reserve). Although human settlement in this area has been low relative to other areas, the connection between the Katavi/Rukwa and Ruaha ecosystems may be threatened by increased human activity and warrants conservation. High levels of historical gene flow were also seen between reserves in the northeast (Tarangire National Park, Swagaswaga Game Reserve) and the central and southwest populations. These connections appear highly threatened due to current land use practices, and may have already suffered a loss of gene flow. Field surveys in the lands surrounding the northeastern reserves are needed to quantify current levels of connectivity and determine whether corridors could be established to maintain or restore gene flow with other reserves. / Graduation date: 2012

The diploma thesis aimed to create a concept of a universal vehicle meeting the requirements for safe transportation of patients with risk of environmental contamination including the possibility of repeated use. The vehicle should meet the highest degree of public health protection, namely the Biological safety levels 4 (BSL 4). The questionnaire was used to gather the information about the current status of Biohazard teams, their material and technical equipment, and the way of transport security, including the possibility of rotating/substitution of the intervening staff. The questionnaire was distributed to the providers of health rescue services in individual regions and in the capital city of Prague. The results of the questionnaire survey formed the basis for processing the concept of the vehicle to ensure the transport of patients suspected of a highly dangerous contagion. The concept of the vehicle should serve as the basis for the real vehicle construction that will be able to provide protection at the level of BSL 4. It counts on a separate cabin for two drivers, a rear cabinet superstructure with a clean area for storing material and medical equipment, and rest facilities for the staff. At the rear, a separate insulating container consisting of an insulating box for patients, a decontamination area for the needs of the rotating staff, and a transfer box for medical supplies and devices. The proposed vehicle brings numerous improvements that meet BSL 4 protection and thus the highest level of the public health protection. The vehicle can carry up to seven patients at one intervention with the risk of environmental contamination. During the transport, it is possible for the staff to rotate continuously. The separate storage of medical supplies and devices ensures the use and degradation of only the necessary materials and devices. To cover the territory of the Czech Republic, the optimal number of six vehicles would be optimal.

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No. of bitstreams: 3 Tese - José Milton de Sousa Filho - vFinal.pdf: 2121088 bytes, checksum: f34ee196cec80f954abee65bfa62f18e (MD5) Tese - José Milton de Sousa Filho - vFinal.pdf: 2121088 bytes, checksum: f34ee196cec80f954abee65bfa62f18e (MD5) Tese - José Milton de Sousa Filho - vFinal.pdf: 2121088 bytes, checksum: f34ee196cec80f954abee65bfa62f18e (MD5) Previous issue date: 2013-08-12 / O presente estudo trata da ‘Estratégia Socioambiental Baseada em Recursos e seu Impacto na Criação de Ambiguidade Causal’ e se propôs a responder a seguinte pergunta de pesquisa: Qual a relação entre estratégia socioambiental baseada em recursos e ambiguidade causal? Mais especificamente, trata criação de ambiguidade causal através da estratégia socioambiental baseada em recursos e capacidades, desta forma, faz sentido teórico considerar a ambiguidade causal como variável dependente, sendo as capacidades socioambientais variáveis independentes (preditoras). Nessa linha, as capacidades baseadas em recursos socioambientais possuem as características causalmente ambíguas preconizadas por Reed e DeFillippi (1990), a saber, tacitividade, complexidade e especificidade. Tais características são essenciais para que o recurso ou capacidade tenha o potencial de gerar ambiguidade causal. Com base no referencial teórico foi estabelecido quais recursos e capacidades tem estreita ligação com as questões socioambientais, ao mesmo tempo em que possuem características causalmente ambíguas. Assim, os seguintes recursos e capacidades emergiram do campo teórico, (a) orientação socioambiental, (b) engajamento com stakeholders, (c) aperfeiçoamento ambiental, e (d) capital humano. Utilizando a técnica estatística regressão linear múltipla, a variável dependente ambiguidade causal foi regredida em função das variáveis independentes que formaram cada um dos quatro citados construtos. Como resultado, apenas as variáveis governança corporativa (construto orientação socioambiental) e sociedade/comunidade (construto engajamento com stakeholders) mostraram-se impactantes positivamente sobre a ambiguidade causal. Por fim, a utilização da ambiguidade causal como variável dependente é fato novo e relevante nos estudos da área de RBV, bem como sua relação com a estratégia socioambiental. Deste modo, pode-se afirmar que os resultados desta pesquisa exploratória tem potencial para ampliar as discussões na intersecção dos estudos de RBV e RSAE, bem como, abre diversas possibilidades para futuras pesquisa, conforme colocado nas conclusões do presente trabalho. / This work is about 'Social and Environmental Resource-Based Strategy and its Impact on the Causal Ambiguity' and aim to answer the following research question: What is the relationship between social and environmental resource-based strategy and causal ambiguity? More specifically, the creation of causal ambiguity through social and environmental resources and capabilities, so it makes sense to consider causal ambiguity as a dependent variable, and the social and environmental capabilities independent variables (predictors). In this line, social and environmental capabilities have causally ambiguous characteristics advocated by Reed and DeFillippi (1990), namely, tacitness, complexity and specificity. These characteristics are essential for the resource or capability has the potential to generate causal ambiguity. Based on the theoretical framework, I established which resources and capabilities is closely linked to social and environmental issues, while having causally ambiguous characteristics. Thus, the following resources and capabilities emerge from the literature, (a) social and environmental orientation, (b) stakeholder engagement, (c) environmental improvement, and (d) human capital. Using multiple linear regression, the dependent variable (causal ambiguity) was regressed in function of the independent variables (that formed the four mentioned constructs). As a result, only corporate governance (social and environmental orientation construct) and society / community (stakeholder engagement construct) impacted positively on the causal ambiguity. Finally, the use of causal ambiguity as a dependent variable is a really new and relevant for future studies in the RBV, as well as the relationship between social and environmental strategy and causal ambiguity. Thus, it can be stated that the results of this exploratory research have potential to broaden the discussion on the intersection of RBV and CSER studies, and open several possibilities for future research, as marked in the conclusions of this work.

The thesis deals with definitions of the crisis management (in the general level with the application into a practice - business branch), further problems of correction and solution of the crisis in the organisation. In the hard-headed part there the student suggests the optimal soltution of the crisis in the specific company.

[ES] En esta tesis de doctorado se utiliza el modelado matemático de zonas térmicas para evaluar la capacidad del control en modos deslizantes, para regular la temperatura interna de un caso de estudio. Se utiliza la técnica de parámetros agrupados para representar los espacios cerrados, que al ser complementada con mediciones experimentales y algoritmos de optimización, permitió construir un simulador para reproducir con una precisión de más del 97% las condiciones del modelo estudiado, y que permitió estudiar el sistema en general mientras se introducen perturbaciones o variaciones en los parámetros del modelo. Inicialmente se utilizaron modelos de escala reducida para caracterizar el efecto termo-aislante de la solución Thermo Skold sobre la temperatura interna, se caracterizó el efecto de la pintura sobre cada uno de los parámetros de transmisión de calor del caso de estudio, lo que permitió entender los ahorros y resultados obtenidos experimentalmente. Posteriormente, se utilizaron los modelos de escala reducida para evaluar la técnica de control en modos deslizantes, por lo que se modeló, simuló y veri ficó experimentalmente la efectividad de la técnica para mantener una temperatura de referencia ja, con un error inferior al 2 %. En la etapa final de la tesis se utilizó un domo geodésico como caso de estudio, el cual fue modelado con un circuito eléctrico propuesto para sus características específi cas. Se realizaron medidas experimentales de las condiciones térmicas del domo geodésico, con las cuales se ajustó el simulador utilizando el algoritmo de optimización Búsqueda de Patrones. Gracias al simulador desarrollado se estudiaron las condiciones de confort térmico y las necesidades de refrigeración del domo, considerando diferentes situaciones y cargas internas por ocupantes y sistemas de refrigeración. / [EN] In this doctoral thesis, the mathematical modeling of thermal zones is used to evaluate the ability of the control in sliding modes, to regulate the internal temperature of a case study. The grouped parameters technique is used to represent the closed spaces, which, when complemented with experimental measurements and optimization algorithms, allowed the construction of a simulator to reproduce the conditions of the model studied with an accuracy of more than 97 %, which allowed studying the system in general while introducing disturbances or variations in the model parameters. Initially, reduced-scale models were used to characterize the thermal insulating effect of the Thermo Skold solution on the internal temperature. The impact of the painting on each one of the heat transfer parameters was studied, which allowed us to understand the savings and results obtained experimentally. Subsequently, the reduced scale models were used to evaluate the control technique in sliding modes, so the effectiveness of the technique was modeled, simulated and verified experimentally to maintain a fixed reference temperature, with an error of less than 2%. In the final stage of the thesis, a geodesic dome was used as a case study, which was modeled with an electrical circuit proposed for its specific characteristics. Experimental measurements of the thermal conditions of the geodesic dome were made, with which the simulator was adjusted using the Pattern Search optimization algorithm. Thanks to the simulator developed, the thermal comfort conditions and the cooling needs of the dome were studied, considering different situations and internal loads by occupants and cooling systems. / [CA] En aquesta tesi de doctorat s'utilitza el modelatge matemàtic de zones tèrmiques per avaluar la capacitat de l'control en maneres lliscants, per regular la temperatura interna d'un cas d'estudi. S'utilitza la tècnica de paràmetres agrupats per representar els espais tancats, que a l'ésser complementada amb mesuraments experimentals i algoritmes d'optimització, va permetre construir un simulador per reproduir amb una precisió de més de l' 97 % les condicions de el model estudiat, i que va permetre estudiar el sistema en general mentre s'introdueixen pertorbacions o variacions en els paràmetres de el model. Inicialment es van utilitzar models d'escala reduïda per caracteritzar l'efecte termo-aïllant de la solució Thermo Skold sobre la temperatura interna, es va caracteritzar l'efecte de la pintura sobre cadascun dels paràmetres de transmissió de calor de l' cas d'estudi, el que va permetre entendre els estalvis i resultats obtinguts experimentalment. Posteriorment, es van utilitzar els models d'escala reduïda per avaluar la tècnica de control en maneres lliscants, de manera que es va modelar, simular i va verificar experimentalment l'efectivitat de la tècnica per mantenir una temperatura de referència fixa, amb un error inferior a el 2 % . En l'etapa final de la tesi es va utilitzar un dom geodèsic com a cas d'estudi, el qual va ser modelat amb un circuit elèctric proposat per les seves característiques especifiques. Es van realitzar mesures experimentals de les condicions tèrmiques de l'dom geodèsic, amb les quals es va ajustar el simulador utilitzant l'algoritme d'optimització Cerca de Patrons. Gràcies a el simulador desenvolupat es van estudiar les condicions de confort tèrmic i les necessitats de refrigeració de la cúpula, considerant diferents situacions i càrregues internes per ocupants i sistemes de refrigeració. / Al programa de becas de doctorados nacionales convocatoria 727 de Colciencias, por todos los recursos aportados durante el desarrollo de mis estudios. Finalmente, a la Universidad Nacional de Colombia sede Manizales y a la Universidad Politècnica de Valencia, que con sus programas de doctorado en ingeniería automática y matemáticas aplicadas contribuyeron en mi formación como investigador. / Florez Montes, F. (2020). Análisis dinámico del confort en edificios con estrategias de control adaptativo en modos deslizantes [Tesis doctoral]. Universitat Politècnica de València. https://doi.org/10.4995/Thesis/10251/153803