Wearable sensors are at the heart of the digital health revolution. Integral to the use of these sensors for monitoring conditions impacting balance and mobility are accurate estimates of joint angles. To this end a simple and novel method of estimating hip joint angles from small wearable magnetic and inertial sensors is proposed and its performance is established relative to optical motion capture in a sample of human subjects. Improving upon previous work, this approach does not require precise sensor placement or specific calibration motions, thereby easing deployment outside of the research laboratory. Specific innovations include the determination of sensor to segment rotations based on functionally determined joint centers, and the development of a novel filtering algorithm for estimating the relative orientation of adjacent body segments. Hip joint angles and range of motion determined from the proposed approach and an existing method are compared to those from an optical motion capture system during walking at a variety of speeds and tasks designed to exercise the hip through its full range of motion. Results show that the proposed approach estimates flexion/extension angle more accurately (RMSE from 7.08 to 7.29 deg) than the existing method (RMSE from 11.64 deg to 14.33 deg), with similar performance for the other anatomical axes. Agreement of each method with optical motion capture is further characterized by considering correlation and regression analyses. Mean ranges of motion for the proposed method are not largely different from those reported by motion capture, and showed similar values to the existing method. Results indicate that this algorithm provides a promising approach for estimating hip joint angles using wearable inertial sensors, and would allow for use outside of constrained research laboratories.

Rodent models are being extensively used to investigate the effects of traumatic injuryand to develop and assess the mechanisms of repair and regeneration. We presentquantitative assessment of 2D kinematics of overground walking and for the first time3D joint angle kinematics of all four limbs during treadmill walking in the intact and inincomplete spinal cord contusion injured (iSCI) adult female Long Evans rats. Phaserelationship between joint angles on a cycle-by-cycle basis and interlimb footfalls areassessed using a simple technique. Electromyogram (EMG) data from major flexor andextensor muscles for each of the hindlimb joints and elbow extensor muscles of theforelimbs synchronized to the 3D kinematics is also obtained in intact rats. EMG activityindicates specific relationships of the neural activity to joint angle kinematics. We findthat the ankle flexors as well as the hip and elbow extensors maintain constant burstduration with changing cycle duration. Overground walking kinematics providesinformation on stance width (SW), stride length (SL) and hindfoot rotation (Rot). SW andRot increased in iSCI rats. Treadmill walking kinematics provides information on jointangle trajectories. In iSCI rats double burst pattern in ankle angle as seen in intact ratsis lost and knee extension and range are reduced. Intra and interlimb coordination isimpaired. Left-right interlimb coordination and forelimb kinematics are not alteredsignificantly. In iSCI rats, maximum flexion of the knee during swing occurs in phasewith the hip as opposed to knee flexion preceeding hip flexion in intact rats. A mildexercise regimen in intact rats over eight weeks does not alter the kinematics.

Tumbling take-offs on floor exercise apparatuses of varying stiffness properties may contribute to apparatus behaviors that lead to increased injury exposure. The purpose of this pilot study was to compare the kinematics, kinetics, and timing performance characteristics of a springfloor and a spring-floor with an added Air FloorTM. Five male international gymnasts performed a forward handspring to forward somersault and a round off, flic flac, backward somersault on a standard spring-floor and a spring-floor with an Air FloorTM. Performances were measured via high-speed video kinematics (lower extremity joint angles and positions), electromyography of eight lower extremity muscles, mean peak forces on the feet, and timing. Comparisons of spring-floor types, lower extremity joint angles, lower extremity muscle activations, foot forces, and selected durations were determined. The spring floor with Air FloorTM resulted in longer take-off contact durations than spring-floor alone. Dynamic knee angles may indicate an unexpected and potentially injurious motion of the triceps surae musculotendinous structures. This pilot and hypothesis generating study has suggested future research examining dynamic knee position and angle changes, the role of spring-floor vibration and stiffness in take-offs, and take-off muscle activation alignment with the stiffness of the spring-floor. Pragmatically, there appears to be a convergence of evidence indicating that a slower frequency response of the spring floor may assist tumbling performance and reduce stress and strain in the lower extremity.

Tumbling take-offs on floor exercise apparatuses of varying stiffness properties may contribute to apparatus behaviors that lead to increased injury exposure. The purpose of this pilot study was to compare the kinematics, kinetics, and timing performance characteristics of a springfloor and a spring-floor with an added Air Floor™. Five male international gymnasts performed a forward handspring to forward somersault and a round off, flic flac, backward somersault on a standard spring-floor and a spring-floor with an Air Floor™. Performances were measured via high-speed video kinematics (lower extremity joint angles and positions), electromyography of eight lower extremity muscles, mean peak forces on the feet, and timing. Comparisons of spring-floor types, lower extremity joint angles, lower extremity muscle activations, foot forces, and selected durations were determined. The spring floor with Air Floor™ resulted in longer take-off contact durations than spring-floor alone. Dynamic knee angles may indicate an unexpected and potentially injurious motion of the triceps surae musculotendinous structures. This pilot and hypothesis generating study has suggested future research examining dynamic knee position and angle changes, the role of spring-floor vibration and stiffness in take-offs, and take-off muscle activation alignment with the stiffness of the spring-floor. Pragmatically, there appears to be a convergence of evidence indicating that a slower frequency response of the spring floor may assist tumbling performance and reduce stress and strain in the lower extremity.

Tumbling take-offs on floor exercise apparatuses of varying stiffness properties may contribute to apparatus behaviors that lead to increased injury exposure. The purpose of this pilot study was to compare the kinematics, kinetics, and timing performance characteristics of a springfloor and a spring-floor with an added Air Floor™. Five male international gymnasts performed a forward handspring to forward somersault and a round off, flic flac, backward somersault on a standard spring-floor and a spring-floor with an Air Floor™. Performances were measured via high-speed video kinematics (lower extremity joint angles and positions), electromyography of eight lower extremity muscles, mean peak forces on the feet, and timing. Comparisons of spring-floor types, lower extremity joint angles, lower extremity muscle activations, foot forces, and selected durations were determined. The spring floor with Air Floor™ resulted in longer take-off contact durations than spring-floor alone. Dynamic knee angles may indicate an unexpected and potentially injurious motion of the triceps surae musculotendinous structures. This pilot and hypothesis generating study has suggested future research examining dynamic knee position and angle changes, the role of spring-floor vibration and stiffness in take-offs, and take-off muscle activation alignment with the stiffness of the spring-floor. Pragmatically, there appears to be a convergence of evidence indicating that a slower frequency response of the spring floor may assist tumbling performance and reduce stress and strain in the lower extremity.

The purpose of this study is to investigate the use of isometric mid-thigh pulls to determine lower-limb asymmetrical strength differences in NCAA D-I athletes. Sixty-six subjects (40 males and 26 females) performed 2 maximal effort isometric pulls over two force plates sampling at 1000 Hz each. Peak force was scaled for body weight, and rate of force development was examined from 0-200ms. Results of the study show subjects' produced significantly greater scaled force with the left leg as compared to the right leg; however, no significant differences existed for rate of force development (RFD). Men exhibited significant differences between both scaled peak force and RFD, while women only showed significant differences in scaled peak force. Of the 66 subjects tested, 6 subjects (5 men and 1 woman) exhibited percent differences of 15% or greater asymmetry for scaled peak force. The results indicate that isometric mid-thigh pulls are a way to show the presence of asymmetries in D-I athletes.

Parkinson's disease (PD) is a neurological condition that can lead to changes to gait and postural stability of people with this condition. Tai Chi (TC) has been recommended for the management of PD by improving muscle strength, balance, and coordination. However, biomechanics research in TC for PD is lacking. This thesis investigated the effects of a biomechanical-based TC intervention program for people in the early-stage of PD by realizing three specific research objectives: 1) to develop a biomechanical-based TC intervention program for PD; 2) to examine the effects of a 12-week TC intervention on gait and postural stability in people with PD, by pre-test and post-test biomechanical analysis of obstacle crossing; 3) to explore the neuromuscular effects of TC intervention on gait and postural stability by analyzing the electromyography (EMG) activity of the lower limb muscles during obstacle crossing. Seven typical TC movements were selected, including Starting Form, Hero Touch Sky, Push Hand Back, Brush Knee and Twist Step, Repulse Monkey, Wave-hand in Cloud, and Lateral Forward Step to develop the TC intervention program. The joint angles, joint moment, and EMG signals of lower limbs muscles were analyzed during performance of the selected TC movements by an experienced TC master aged 38 years. Results showed that the selected TC movements are characterized by multidirectional movements, greater joint movement angles of the lower limb, and more active muscle activity than walking. The TC intervention program was formed based on the biomechanics analysis of the seven TC movements. The program consisted of 5-10 min warm up, 40 minutes of core activities, and 5 min cool down. To examine the effects of a biomechanical-based TC intervention program on gait and postural stability and to explore the neuromuscular effects of TC intervention on the lower limb muscles in people with PD, fifteen individuals in the early stage of PD (n = 15, Hoehn and Yahr stages 1 to 2; age 72.0 ± 6.9) participated in a 12-week online TC intervention, and 15 age- and sex-matched healthy participants (n = 15) served as control. The 3D motion data of the lower limb and EMG signals from the rectus femoris, adductor longus, tibialis anterior, semitendinosus, gluteus medius, tensor fasciae latae, and medial and lateral gastrocnemius muscles were collected during obstacle crossing from both groups using Vicon motion analysis system before intervention in both groups and after TC intervention in the TC group. Obstacle crossing was used to challenge the participants' gait and postural stability. Gait was assessed by measuring the temporospatial parameters such as crossing stride length, crossing step length, and crossing speed. Postural stability was assessed by measuring toe and clearance distance, pre- and post-horizontal distance, displacement and velocity of center of mass (COM), and COM-center of pressure (COP) separation. To examine the neuromuscular activity of the lower limbs following TC training, the ratio of the peak EMG, the integrated EMG (iEMG), and the ratio of the peak EMG and iEMG antagonistic pairs of the leading and trailing limb were examined during obstacle crossing and walking. In addition, the timed up-and-go test (TUG) and single-leg stance with eyes open and closed were tested. VICON Nexus, custom MATLAB scripts, and SPSS software (version 20) were used to analyze the data. Analysis of the PD participants' obstacle crossing performance revealed that they had significantly slower gait speed, smaller hip flexion angles, and larger knee adduction angles of the trailing limb, significantly larger mediolateral (ML) COM displacement and COM-COP separation distance, and significantly higher peak EMG ratios of the adductor longus, gluteus medius, and tensor fasciae latae (p < 0.05) than the healthy participants. Following the 12-week TC intervention, the PD participants had significantly increased crossing stride length, significantly decreased ML COM-COP separation (p < 0.05) and significantly increased AP COM displacement (p < 0.05), and increased EMG activity of the tibialis anterior in the leading and trailing limbs during obstacle crossing, whereas the activity of the gluteus medius and adductor longus in the leading limb decreased (p < 0.05). Moreover, the significant differences in the EMG of the gluteus medius and tensor fasciae latae muscles between PD and healthy participants found in pre-test were no longer present. After the TC intervention, the PD participants significantly improved their performance on the TUG test (p = 0.002). Therefore, people with early-stage PD presented changed gait and postural stability as well as changed neuromuscular activity of the lower limb. The 12-week online biomechanical-based TC intervention improved their gait and postural stability, particularly dynamic postural stability as measured by the COM-COP separation in people with early-stage PD. Compared to walking, performing the TC movements involved larger changes in the lower limb angles, range of motion, and higher muscle activity, particularly in the hip abductors and adductors. These characteristics of the TC movements could provide training to strengthen the muscles and improve the range of motion of the lower limbs. The gait and postural stability improvements following TC intervention are consistent with the neuromuscular activity changes in gluteus medius, tensor fasciae latae, and adductor longus muscles, indicating the mechanisms of TC training. The 12-week online biomechanical-based TC intervention program helped to decrease the ML COM-COP separation distance and could be used for the management of PD in the early stages of this condition.

<p> A slow concentric contraction of the tibialis anterior muscle was imaged using Brightness-Mode Ultrasonography (BMU) from different probe orientations to determine the effect of probe orientation on the measurement of muscle architecture parameters (MAP). Nine contractions were performed by each of nine subjects. Each contraction was visualized with a different probe orientation on the anterior surface of the muscle. Data was taken from the same four joint angles from all contractions from all subjects and then compared for values of torque, tibialis anterior EMG and measures of MAP which include; fascicle length (FL), pennation angle (PA) and muscle thickness (MT).</p> <p> The results of an analysis of variance found a significant difference between joint angles for measures of FL and PA but not MT. A significant difference was found between probe rotations for the measures of FL and MT but not PA.</p> <p> A reliability study was performed for measures of MAP and found the coefficient of variation for FL and PA to be less than 8% both with and without the use of an image filter. The coefficient of variation for MT was found to be less than 2% which shows this measure to be highly reliable.</p> <p> Equations and Figures were developed, corresponding to the observations and assumptions made by MAP researchers using BMU, to predict the effect of probe orientation on the measures of MAP.</p> <p> The results of this study indicate that ultrasound probe orientation affects measures of MAP but the effect either cannot be predicted from a simple geometric model or the error in the measurement technique does not allow this type of comparison. Specific guidelines are outlined in this paper to determine the proper probe placement and orientation to measure MAP using BMU for the tibialis anterior muscle.</p> / Thesis / Master of Science (MSc)

Cross-country (c.c.) skiing is a complex sport discipline from both physiological and biomechanical perspectives, with varying course topographies that require different proportions of the involved sub-techniques to be utilised. A relatively new event in c.c. skiing is the sprint race, involving four separate heats, each lasting 2-4 min, with diverse demands from distance races associated with longer durations. Therefore, the overall aim of the current thesis has been to examine the biomechanical and physiological factors associated with sprint c.c. skiing performance through novel measurements conducted both in the field (Studies I-III) and the laboratory (Studies IV and V). In Study I sprint skiing velocities and sub-techniques were analysed with a differential global navigation satellite system in combination with video recording. In Studies II and III the effects of an increasing velocity (moderate, high and maximal) on the biomechanics of uphill classical skiing with the diagonal stride (DS) (Study II) and herringbone (HB) (Study III) sub-techniques were examined. In Study I the skiers completed the 1,425 m (2 x 712 m) sprint time trial (STT) in 207 s, at an average velocity of 24.8 km/h, with multiple technique transitions (range: 21-34) between skiing techniques (i.e., the different gears [G2-7]). A pacing strategy involving a fast start followed by a gradual slowing down (i.e., positive pacing) was employed as indicated by the 2.9% faster first than second lap. The slower second lap was primarily related to a slower (12.9%) uphill velocity with a shift from G3 towards a greater use of G2. The maximal oxygen uptake ( O2max) was related to the ability to maintain uphill skiing velocity and the fastest skiers used G3 to a greater extent than G2. In addition, maximal speed over short distances (50 and 20 m) with the G3 and double poling (DP) sub-techniques exerted an important impact on STT performance. Study II demonstrated that during uphill skiing (7.5°) with DS, skiers increased cycle rate and cycle length from moderate to high velocity, while cycle rate increased and cycle length decreased at maximal velocity. Absolute poling, gliding and kick times became gradually shorter with an elevated velocity. The rate of pole and leg force development increased with elevated velocity and the development of leg force in the normal direction was substantially faster during skiing on snow than previous findings for roller skiing, although the peak force was similar in both cases. The fastest skiers applied greater peak leg forces over shorter durations. Study III revealed that when employing the HB technique on a steep uphill slope (15°), the skiers positioned their skis laterally (“V” between 25 to 30°) and planted their poles at a slight lateral angle (8 to 12°), with most of the propulsive force being exerted on the inside forefoot. Of the total propulsive force, 77% was generated by the legs. The cycle rate increased across all three velocities (from 1.20 to 1.60 Hz), while cycle length only increased from moderate to high velocity (from 2.0 to 2.3 m). Finally, the magnitude and rate of leg force generation are important determinants of both DS and HB skiing performance, although the rate is more important in connection with DS, since this sub-technique involves gliding. In Studies IV and V skiers performed pre-tests for determination of gross efficiency (GE), O2max, and Vmax on a treadmill. The main performance test involved four self-paced STTs on a treadmill over a 1,300-m simulated course including three flat (1°) DP sections interspersed with two uphill (7°) DS sections. The modified GE method for estimating anaerobic energy production during skiing on varying terrain employed in Study IV revealed that the relative aerobic and anaerobic energy contributions were 82% and 18%, respectively, during the 232 s of skiing, with an accumulated oxygen (O2) deficit of 45 mL/kg. The STT performance time was largely explained by the GE (53%), followed by O2 (30%) and O2 deficit (15%). Therefore, training strategies designed to reduce energetic cost and improve GE should be examined in greater detail. In Study V metabolic responses and pacing strategies during the four successive STTs were investigated. The first and the last trials were the fastest (both 228 s) and were associated with both a substantially larger and a more rapid anaerobic energy supply, while the average O2 during all four STTs was similar. The individual variation in STT performance was explained primarily (69%) by the variation in O2 deficit. Furthermore, positive pacing was employed throughout all the STTs, but the pacing strategy became more even after the first trial. In addition, considerably higher (~ 30%) metabolic rates were generated on the uphill than on the flat sections of the course, reflecting an irregular production of anaerobic energy. Altogether, a fast start appears important for STT performance and high work rates during uphill skiing may exert a more pronounced impact on skiing performance outdoors, due to the reduction in velocity fluctuations and thereby overall air-drag. / <p>Vid tidpunkten för disputationen var följande delarbeten opublicerade: delarbete 5 inskickat</p><p>At the time of the doctoral defence the following papers were unpublished: paper 5 submitted</p>