The aims of this study were to document the levels of cobalamin, folate, methylmalonic acid (MMA) and total homocysteine (tHcy) in serum and their relations to symptoms, clinical findings, and other factors in order to improve the possibilities of detecting early deficiency of vitamin B12 or folate, and to study the effects of cobalamin and folic acid treatment over a three-year period. The study population consisted of a 20% random sample of persons 70 years or older living in Älvkarleby in mid-Sweden. They were invited to a survey and 224 (88.4%) persons responded. Data were obtained by questionnaire, laboratory investigations and physical examination for the period 1993 – 1999. In a multivariate analysis performed at baseline, serum MMA and tHcy were significantly and independently correlated to age, serum cobalamin, and creatinine levels, and tHcy also to sex and serum folate. Neither serum cobalamin, folate, MMA nor tHcy had any significant correlation to haemoglobin or mean red cell volume. Almost half of the study population had signs of low tissue levels of vitamin B12 or folate. Among those who took multivitamin preparations, the proportion was much lower, 25%. Among traditional symptoms and clinical findings that have been linked to vitamin B12 or folate tissue deficiency, only changes in the tongue mucosa and mouth angle stomatitis were significantly associated with abnormal serum folate and tHcy levels. Traditional symptoms of vitamin deficiency may appear later in the course. 69 persons who had laboratory indications of early or overt tissue deficiency of vitamin B12 or folate and who had no ongoing vitamin treatment were given cobalamin for six months. Those whose MMA or tHcy levels did not normalise were given folic acid in addition to cobalamin. After further treatment for three months, all persons but one had normal levels. The laboratory effect still remained after three years of treatment. There was a tendency towards improvement of vibration sense, especially in the long nerve paths, and improvement of neurological symptoms and oral mucosa findings. Conclusion: A substantial proportion of elderly persons have laboratory signs of incipient tissue deficiency of vitamin B12 and folate. Treatment normalises lab parameters and some symptoms.

TITLE: Strategic plan of association Vraťme dětem pohyb, z.s. PROBLEM: The diploma thesis examines the strategic management of a nonprofit sport organization, respectively long-term planning of association Vraťme dětem pohyb, z.s. The association Vraťme dětem pohyb, z.s. currently cooperates with organization Gorila MMA CLUB, s.r.o. These emerging sports organizations were separated from the original associaton PriMMAt Gym Praha, z.s. The diploma thesis therefore contributes to the solution of current problem and its results will be practically usable. SUBJECT: The subjekt of the thesis is the sport association Vraťme dětem pohyb, z.s. Its main purpose is a publicly beneficial aktivity, namely the organization and operation of leisure activities aimed at children and youth. The association especially focuses on the area of body culture, sport and other club activities. Their main purpose is to operate Gorila Junior children's sports club with elements of combat sports and self-defense. The Sports Association i salso preparing a project for generic sports training for children. MAIN GOAL: Main goal is to create strategic plan proposal of sports association plan Vraťme dětem pohyb, z.s. for September 2018 - September 2021. PARTIAL GOALS: Partial goals are to characterize the organization and its...

Submitted by Johnny Rodrigues (johnnyrodrigues@ufcg.edu.br) on 2018-09-28T18:12:22Z No. of bitstreams: 1 VILMA MARIA SUDÉRIO - DISSERTAÇÃO PPGEQ 1995..pdf: 12571558 bytes, checksum: 00b0d5b9a33da42cdeac794bde348de8 (MD5) / Made available in DSpace on 2018-09-28T18:12:22Z (GMT). No. of bitstreams: 1 VILMA MARIA SUDÉRIO - DISSERTAÇÃO PPGEQ 1995..pdf: 12571558 bytes, checksum: 00b0d5b9a33da42cdeac794bde348de8 (MD5) Previous issue date: 1995-11-06 / Neste trabalho investigou-se a atividade catalítica da vermiculita natural (V-N) e trocada com cromo (III), (V-Cr) e cobalto (II), (V-Co), na reação de polimerização aquosa do metil metacrilato (MMA). utilizando bissulfito de sódio como iniciador. Foi estudada a influência de vários fatores, como: presença dos catalisadores V-N, V-Cr e V-Co. temperatura de calcinação dos catalisadores, massa dos catalisadores, tempo de polimerização, teor de cátions cromo (III) e cobalto(II) trocados, concentração de MMA e NaHSO? e temperatura de polimerização, sobre a velocidade de polimerização do MMA. A partir dos resultados obtidos foram observados os seguintes efeitos: 1) a V-N apresentou um efeito catalítico na reação, sendo que este efeito foi mais significativo quando os catalisadores V-Cr e V-Co foram utilizados, e que a V-Cr apresentou o maior efeito catalítico. A atividade catalítica cresceu, com o aumento dos teores dos cátions cromo e cobalto trocados; 2) o aumento da temperatura de calcinação de 100 até 800°C, das amostras V-Cr e V-Co, aumentaram a sua atividade catalítica. Entretanto, este aumento foi maior na temperatura de 400°C: 3) os efeitos dos outros fatores, citados no paragrafo anterior, mostraram um aumento na conversão do MMA. Porém, nos altos valores de conversão, foi observada a desativação dos sítios ativos, devido ao recobrimento das partículas dos catalisadores, pelo polímero formado; 4) o efeito catalítico das amostras estudadas é explicado com base no mecanismo em que a presença dos cátions de metais de transição na superfície da vermiculita. favorecem a dissociação do iniciador, produzindo maior quantidade de radicais de bissulfito, que em conseqüência aumentam a taxa de polimerização. / This work presents an investigation of the catalytic activity of the natural vermiculite (V-N) and that of vermiculite exchanged with chromium (III) (V-Cr) and Cobalt (II) (V-Co) for the aqueous polymerization of metil methacrylate (MMA), using sodium bissulfite as an initiator. The influence of various factors, as the presence of catalysts V-N, V-Cr e V-Co, calcination temperature of catalysts, catalyst mass, polymerization time, amount of exchanged chromium and cobalt cations, MMA and NaHSO? concentration and polymerization temperature, on the rate of polymerization of MMA has been studied. Based on the results obtained the following effects have been observed: 1) the samples of V-N, V-Cr and V-Co have shown catalytic activity on the aqueous polymerization reaction of MMA, and V-Cr being more significant. The catalytic activity was increased with the increase of the amounts of exchanged chromium and cobalt cations; 2) the increase in the calcination temperature from 100 to 800°C for the samples of V-Cr and V-Co increased their catalytic activity. However, this increase was highest for 400°C; 3) the effect of other factors mentioned in the previous paragraph also showed an increase in MMA conversion. However, for higher values of conversion, due to covering of the catalyst particles by the polymer formed, deactivation of the active sites was observed; 4) the catalytic effect of the samples studied is explained on the basis of mechanism that the presence of transition metal cations on the vermiculite surface favor the initiator dissociation and thereby more bissulfite radicals are produced which in consequence increase the polymerization rate of the MMA.

This graduate work deals with the study and preparation of gel polymer electrolytes with flame retardants for lithium-ion batteries. The theoretical part describes the types of electrolytes, their features, benefits, how they differ and where they are used in detail. The basis of this section is gel electrolytes with flame retardants, to measure their electrical and electrochemical properties. The experimental part deals with the preparation of samples of gel electrolytes with different percentages of flame retardant, where varied species of flame retardants and measuring their electrical conductivity and potential windows. Impedance spectroscopy, cyclic voltammetry and dynamic-analytical thermal analysis were selected as measuring methods.

This work deals with preparation of PMMA based gel polymer electrolytes with high fire safety and high ionic conductivity. In the theoretical part of the work GPEs for Li – ion accumulators, fire safety tests, fire retardants are mentioned. Preparation of GPEs, electrical and other properties are described in the experimental part. Furthermore, new possible methods of gel preparation are discussed.

The diploma thesis presents a media image of one of the fastest growing sports in the world. Mixed Martial Arts, abbreviation MMA, has a history in the Czech Republic since the 1990s. The media portrayal of male and female Mixed Martial Arts represents one of the aspects that are not fully covered in the Czech Republic. With the help of qualitative and quantitative content analysis, articles from the four most read Czech printed periodicals are explored - Blesk, Mladá Fronta DNES, Právo and Sport and four Czech news websites - Blesk.cz, iDNES.cz, Sport.cz and iSport.cz. A total of 1331 articles are analyzed in the research. The main goal of the work was to map the media image of this sport and to point out possible differences in referring to female and male athletes. The results of the research showed that although the female MMA received significantly less media attention, there was no downplay on the abilities of the female athletes. The secondary goal of the work was to discover and analyze possible stereotypes that are associated with Mixed Martial Arts. Out of a total of 1331 articles, stereotypes were traced only in 34 cases. The analysis traced a stereotype associated with the characteristics and visage of female athletes and a stereotype called Bad Guys, which portrayed MMA as a brutal sport.

Dynamic modelling and optimization of three different processes namely (a) bulk polymerization of styrene, (b) solution polymerization of methyl methacrylate (MMA) and (c) emulsion copolymerization of Styrene and MMA in batch and semi-batch reactors are the focus of this work. In this work, models are presented as sets of differential-algebraic equations describing the process. Different optimization problems such as (a) maximum conversion (Xn), (b) maximum number average molecular weight (Mn) and (c) minimum time to achieve the desired polymer molecular properties (defined as pre-specified values of monomer conversion and number average molecular weight) are formulated. Reactor temperature, jacket temperature, initial initiator concentration, monomer feed rate, initiator feed rate and surfactant feed rate are used as optimization variables in the optimization formulations. The dynamic optimization problems were converted into nonlinear programming problem using the CVP techniques which were solved using efficient SQP (Successive Quadratic Programming) method available within the gPROMS (general PROcess Modelling System) software. The process model used for bulk polystyrene polymerization in batch reactors, using 2, 2 azobisisobutyronitrile catalyst (AIBN) as initiator was improved by including the gel and glass effects. The results obtained from this work when compared with the previous study by other researcher which disregarded the gel and glass effect in their study which show that the batch time operation are significantly reduced while the amount of the initial initiator concentration required increases. Also, the termination rate constant decreases as the concentration of the mixture increases, resulting rapid monomer conversion. The process model used for solution polymerization of methyl methacrylate (MMA) in batch reactors, using AIBN as the initiator and Toluene as the solvent was improved by including the free volume theory to calculate the initiator efficiency, f. The effects of different f was examined and compared with previous work which used a constant value of f 0.53. The results of these studies show that initiator efficiency, f is not constant but decreases with the increase of monomer conversion along the process. The determination of optimal control trajectories for emulsion copolymerization of Styrene and MMA with the objective of maximizing the number average molecular weight (Mn) and overall conversion (Xn) were carried out in batch and semi-batch reactors. The initiator used in this work is Persulfate K2S2O8 and the surfactant is Sodium Dodecyl Sulfate (SDS). Reduction of the pre-batch time increases the Mn but decreases the conversion (Xn). The sooner the addition of monomer into the reactor, the earlier the growth of the polymer chain leading to higher Mn. Besides that, Mn also can be increased by decreasing the initial initiator concentration (Ci0). Less oligomeric radicals will be produced with low Ci0, leading to reduced polymerization loci thus lowering the overall conversion. On the other hand, increases of reaction temperature (Tr) will decrease the Mn since transfer coefficient is increased at higher Tr leading to increase of the monomeric radicals resulting in an increase in termination reaction.

Title: Evaluation of postural stability in subjects engaged in combatand non-contact sports Objectives: The aim of this diploma thesis is to investigate the influence of contact itself during sport activities on postural stability of athletes. Methods: Into this quasi-experiment study there were picked 16 atheletes (n=16) in age from 22 to 35 years. Selected individuals were divided into two groups of eight according to their sporting activity (combat sports, baseball. In the mentioned individuals the postural stability was measured. To measure postural stability the computerized dynamic posturography of EquiTest Smart System from Neurocom was used. Measured data were processed using Neurocom Balance Manager Software. For the analysis of the data following statistical methods - paired t-test, Mann-Whitney test and rate of clinical signifikance (Cohen's d) were used. Results: The results indicate that individuals performing in combat sports were reaching higher mean scores in Limits of Stability than baseball players. This fact has been statistically and clinically proven. On the other hand baseball players reached higher mean Equilibrium Scores in Sensory organization test, however this fact has not been statistically nor clinically proven. No significant differences between the groups in motor...

由於國內金融自由化的起步較歐美、等先進國家晚，因此，金融創新的活動在國內金融市場一直落後其他先進國家。在瞭解近三十年來金融創新的發展過程，透過學習歐、美等先進國家在金融創新產品上的發展經驗，將可以縮短我國金融業者在金融創新活動上的摸索時間，進而加速提升其金融創新的開發能力。 美林證券在1977年首先推出「現金管理帳戶」（Cash Management Account；簡稱CMA），該帳戶主要提供的服務包括：買賣貨幣市場共同基金、證券交易管理帳戶、簽發支票、信用卡服務、融資權益、與自動提款機提款等功能。國內之華信銀行於民國89年也率先推出類似「現金管理帳戶」的金融創新產品，稱為「投資管理帳戶」（Money Management Account；簡稱MMA）。美林證券在成功開發「現金管理帳戶」之後，更將該產品結合美林證券本身在財務專業上的優勢，提供全面性的財務金融規劃，根據每個投資人其生命週期中的潛在資金需求及收入，例如：退休基金、結婚基金、子女教育基金等，設計出最適合該投資人的投資理財計畫。 由於美林證券「現金管理帳戶」的推出，打破了美國Glass-Steagall Act長久以來商業銀行與投資銀行業務分離的限制，因此，本論文也將從美國G-S法案的立法精神與基本原理出發，探討美國商業銀行跨足證券業務的發展過程以及G-S法案存在的必要性。並且透過美林證券成功開發「現金管理帳戶」的經驗，來探討我國證券商目前若開發該創新產品，可能會面臨到的障礙並且提供相關建議。 最後，透過寄發問卷的研究方式，從我國證券商的角度分析未來「現金管理帳戶」在我國金融市場上發展的可行性，得出實證結論如下： 1.我國證券商對於承作現金管理帳戶的意願受限於國內金融相關法規的限制。 2.多數證券商看好未來現金管理帳戶之發展，並同意承作現金管理帳戶能實際發揮證券商的投資理財專業。 3.未來主管機關應朝向建立公平競爭的金融環境、強化我國自律組織功能發展。 4.國內多數券商皆非常注重專業人才之培訓，因此，未來在開發現金管理帳戶之專業領域上，必會有更大的發揮空間。

Interest for business models and business modeling has increased rapidly since the mid-1990‘s and there are numerous approaches used to create business models. The business model concept has many definitions which can lead to confusion and slower progress in the research and development of business models. A business model ontology (BMO) was created in 2004 where the business model concept was conceptualized based on an analysis of existing literature. A few years later the Business Model Canvas (BMC) was published; a popular business modeling approach providing a high-level, semi-formal approach to create and communicate business models. While this approach is easy to use, the informality and high-level approach can cause ambiguity and it has limited computer-aided support available. In order to propose a solution to address this problem and facilitate the development and communication of Business Model Canvas models, two artifacts are created, demonstrated and evaluated; a structured metamodel for the Business Model Canvas and its implementation in an OMG standards-based modeling tool to provide tool support for BMC modeling.This research is carried out following the design science approach where the artifacts are created to better understand and improve the identified problem. The problem and its background are explicated and the planned artifacts and requirements are outlined. The design and development of the artifacts are detailed and the resulting BMC metamodel is presented as a class diagram in Unified Modeling Language (UML) and implemented to provide tool support for BMC modeling. A demonstration with a business model and an evaluation is performed with expert interviews and informed arguments.The creation of a BMC metamodel exposed some ambiguity in the definition and use of the Business Model Canvas and the importance of graphical presentation and flexibility in the tools used.The evaluation of the resulting artifacts suggests that the artifacts do facilitate the development and communication of the Business Model Canvas models by improving the encapsulation and communication of information in a standardized way and thereby the goals of the research are met.