京都大学 / 0048 / 新制・課程博士 / 博士(情報学) / 甲第21390号 / 情博第676号 / 新制||情||117(附属図書館) / 京都大学大学院情報学研究科知能情報学専攻 / (主査)教授 鹿島 久嗣, 教授 山本 章博, 教授 下平 英寿 / 学位規則第4条第1項該当 / Doctor of Informatics / Kyoto University / DFAM

An initiative to standardize the nomenclature in Sweden started in 2016 along with the creation of the local database Medical Information Quality Archive (MIQA) and a national radiotherapy register on Information Network for CAncercare (INCA). A problem of identifying the clinical tumor volume (CTV) structures and prescribed dose arose when the consecutive number, which is added to the CTV-name, was made inconsistently in MIQA and INCA. Deep neural networks (DNN) were promising tools to solve the multi-label classification task of the CTV to enable automatic labeling in the database. Prostate cancer patients that often have more than one type of organ in the same CTV structure were chosen for proof of concept. The DNN used supervised training in a 2D fashion where the radiation therapy (RT) structures along with the CT image were fed, slice by slice, to AlexNet and VGGNet to label the CTV structures in the local database system MIQA and INCA. The study also includes three methods to classify a final label for the CTV structure since the model makes the predictions on each slice. The three methods were maximum method by taking the maximum prediction for each class, minimum method by taking the minimum prediction for each class and occurrence method. The occurrence method chooses the maximum prediction if the network has predicted the class over 0.5 at least two times and the minimum prediction if not. The DNN and volume classification methods performed well where the maximum and occurrence method performed the best and can be used to interpret RT volumes in MIQA and INCA for prostate cancer patients. This novel study gives promising results for the future development of deep neural networks classifying RT structures for more than one type of cancer patient. / Ett initiativ för att standardisera nomenklaturen i Sverige startade 2016 tillsammans med skapandet av den lokala databasen Medical Information Quality Archive (MIQA) och ett nationellt radioterapikvalitetsregister på plattformen Information Network for CAncercare (INCA). Ett problem med att identifiera kliniska tumörvolymstrukturer (CTV-strukturer) och ordinerad dos uppstod när de på varandra följande siffrorna, som adderas till CTV-namnet för att skilja de olika CTV:erna från varandra, gjordes inkonsekvent i MIQA och INCA. Djupa neurala nätverk (DNN) är lovande verktyg för att lösa klassificeringen av CTV för att möjliggöra automatisk annotering för multippla etiketter i databasen. Prostatacancerpatienter vars radioterapistrukturer (RT-strukturer) ofta innehåller fler än ett organ användes därför för att bevisa konceptet för fleretikettsklassificering. DNN:et använde övervakad inlärning av 2D-bilder där RT-strukturerna tillsammans med CT-bilderna matades in, snitt för snitt, till AlexNet och VGGNet för att namnge CTV-strukturerna i det lokala databassystemet MIQA och sedan i INCA. Studien inkluderar även tre metoder för en slutlig strukturetikett eftersom modellen gör sina förutsägelser på varje snitt. Metoderna var maximum där den högsta förutsägelsen noteras för varje klass, minimum där den lägsta förutsägelsen noteras för varje klass och förekomst där den högsta förutsägelsen noteras om klassen har fått minst två förutsägelser över 0.5 annars noteras den lägsta förutsägelsen. DNN:en och volymetikettmetoderna gav bra resultat där maximum- och förekomstmetoden gav bäst resultat och kan användas för att tolka RT-volymer i MIQA och INCA för prostatacancerpatienter. Denna nya studie ger lovande resultat för framtida utveckling av djupa neurala nätverk som klassificerar strukturer från mer än en typ av cancerpatient.

Natural language (NL) is a common medium humans use to express ideas and communicate with others, while programming languages (PL) are the ``language'' humans use to communicate with machines. As NL and PL were designed for different purposes, a considerable difference exists in the structure and capabilities. Programming using PL can take novices months to learn. Meanwhile, users are already familiar with NL. Therefore, natural language programming (NLPr) holds excellent potential by giving non-experts the ability to ``program'' with the language they already know and a Low-Code/No-Code development experience. However, many challenges with developing NLPr systems are yet to be addressed, namely how to disambiguate NL semantics, validate inputs and provide helpful feedback, and generate the executable programs based on semantic meanings effectively. This dissertation addresses these issues by proposing a Controlled Object-Oriented Language (COOL) model to disambiguate and analyze the English inputs' semantic meanings and implement a LEGO robot NLPr platform. Two main approaches that connect the current research in general-purpose NLP to NLPr are taken: (1) A domain-specific lexicon and function library serve as the syntax and semantic space. Even though NL can be complex and expressive, functions for the specific robot domain can be fulfilled with libraries built of a finite set of objects and functions. (2) An error-reporting and feedback mechanism detects erroneous sentences, explains possible reasons, and provides debugging and rewriting suggestions. The error-reporting and feedback systems are developed with a hybrid approach that combines rule-based methods such as FSM and dependency-based structural analysis with the data-based multi-label classification (MLC) method. Experiment results and user studies show that, with the proposed model and approaches reducing the ambiguity within the target domain, the NLPr system can process a relatively expressive controlled NL for robot motion control and generate executable codes based on the English input. When the system is confronted with erroneous sentences, it produces error messages, suggestions, and example sentences for users. NL's structural and semantic information can be transformed into the intermediate representations used for program synthesis with the language model and system proposed to resolve the situation where the considerable amount of data needed for a data-based model is unavailable. / Doctor of Philosophy / Natural language (NL) is one of the most common mediums humans use daily to express and explain ideas and communicate with each other. In contrast, programming languages (PL) are the ``language'' humans use to communicate with machines. Because of the difference in the purpose, media, and audience, there is a considerable difference in their structure and capabilities. NL is more expressive and natural and sometimes can be rather complex, while PL is primarily short, straightforward, and not as expressive as NL. The need for programming has increased in recent years. However, the learning curve of programming languages can easily be months or more for novice users to learn. At the same time, all potential users are familiar with at least one NL. As such, natural language programming (NLPr), a technology that enables people to program with NL, holds excellent potential since it gives non-experts the ability to ``program'' with the language they already know and a Low-Code or even No-Code development experience. However, despite recent research into NLPr, many challenges with developing NLPr systems are yet to be addressed, namely how to disambiguate natural language semantics, how to validate inputs and provide helpful feedback with a limited amount of data, and how to effectively generate the executable programs based on the semantic meanings. This dissertation addresses these issues by proposing a Controlled Object-Oriented Language (COOL) model to disambiguate and analyze the English inputs' semantic meanings and implement a LEGO robot NLPr platform. Two main approaches that connect the current research in general-purpose NLP techniques to NLPr are taken: (1) The first is developing a domain-specific lexicon and function library with the designed COOL model to serve as the syntax and semantic space. Even though natural language can be extremely complex and expressive, the functions for the specific robot domain can be fulfilled with libraries built of a finite set of objects and functions. (2) An error-reporting and feedback mechanism detects erroneous sentences, explains possible reasons, and provides debugging and rewriting suggestions. The error-reporting and feedback systems are developed with a hybrid approach that combines rule-based methods such as FSM and dependency-based structural analysis with the data-based multi-label classification (MLC) method. Experiment results and user studies show that, with the proposed language model and approaches reducing the ambiguity within the target domain, the designed NLPr system can process a relatively expressive controlled natural language designed for robot motion control and generate executable codes based on the semantic information extracted. When the NLPr system is confronted with erroneous sentences, it produces detailed error messages and provides suggestions and sample sentences for possible fixes to users. NL's structural and semantic information can be transformed into the intermediate representations used for program synthesis with the simple language model and system proposed to resolve the situation where the considerable amount of data needed for a data-based model is unavailable.

Many real-world problems like hand-written digit recognition or semantic scene classification are treated as multiclass or multi-label classification prob-lems. Solutions to these problems using support vector machines (SVMs) are well studied in literature. In this work, we focus on building sparse max-margin classifiers for multiclass and multi-label classification. Sparse representation of the resulting classifier is important both from efficient training and fast inference viewpoints. This is true especially when the training and test set sizes are large.Very few of the existing multiclass and multi-label classification algorithms have given importance to controlling the sparsity of the designed classifiers directly. Further, these algorithms were not found to be scalable. Motivated by this, we propose new formulations for sparse multiclass and multi-label classifier design and also give efficient algorithms to solve them. The formulation for sparse multi-label classification also incorporates the prior knowledge of label correlations. In both the cases, the classification model is designed using a common set of basis vectors across all the classes. These basis vectors are greedily added to an initially empty model, to approximate the target function. The sparsity of the classifier can be controlled by a user defined parameter, dmax which indicates the max-imum number of common basis vectors. The computational complexity of these algorithms for multiclass and multi-label classifier designisO(lk2d2 max), Where l is the number of training set examples and k is the number of classes. The inference time for the proposed multiclass and multi-label classifiers is O(kdmax). Numerical experiments on various real-world benchmark datasets demonstrate that the proposed algorithms result in sparse classifiers that require lesser number of basis vectors than required by state-of-the-art algorithms, to attain the same generalization performance. Very small value of dmax results in significant reduction in inference time. Thus, the proposed algorithms provide useful alternatives to the existing algorithms for sparse multiclass and multi-label classifier design.

[pt] O segmento offshore de produção de petróleo é o principal produtor nacional desse insumo. Nesse contexto, inspeções submarinas são cruciais para a manutenção preventiva dos equipamentos, que permanecem toda a vida útil em ambiente oceânico. A partir dos dados de imagem e sensor coletados nessas inspeções, especialistas são capazes de prevenir e reparar eventuais danos. Tal processo é profundamente complexo, demorado e custoso, já que profissionais especializados têm que assistir a horas de vídeos atentos a detalhes. Neste cenário, o presente trabalho explora o uso de modelos de classificação de imagens projetados para auxiliar os especialistas a encontrarem o(s) evento(s) de interesse nos vídeos de inspeções submarinas. Esses modelos podem ser embarcados no ROV ou na plataforma para realizar inferência em tempo real, o que pode acelerar o ROV, diminuindo o tempo de inspeção e gerando uma grande redução nos custos de inspeção. No entanto, existem alguns desafios inerentes ao problema de classificação de imagens de inspeção submarina, tais como: dados rotulados balanceados são caros e escassos; presença de ruído entre os dados; alta variância intraclasse; e características físicas da água que geram certas especificidades nas imagens capturadas. Portanto, modelos supervisionados tradicionais podem não ser capazes de cumprir a tarefa. Motivado por esses desafios, busca-se solucionar o problema de classificação de imagens submarinas a partir da utilização de modelos que requerem menos supervisão durante o seu treinamento. Neste trabalho, são explorados os métodos DINO (Self-DIstillation with NO labels, auto-supervisionado) e uma nova versão multi-label proposta para o PAWS (Predicting View Assignments With Support Samples, semi-supervisionado), que chamamos de mPAWS (multi-label PAWS). Os modelos são avaliados com base em sua performance como extratores de features para o treinamento de um classificador simples, formado por uma camada densa. Nos experimentos realizados, para uma mesma arquitetura, se obteve uma performance que supera em 2.7 por cento o f1-score do equivalente supervisionado. / [en] The offshore oil production segment is the main national producer of this input. In this context, underwater inspections are crucial for the preventive maintenance of equipment, which remains in the ocean environment for its entire useful life. From the image and sensor data collected in these inspections,experts are able to prevent and repair damage. Such a process is deeply complex, time-consuming and costly, as specialized professionals have to watch hours of videos attentive to details. In this scenario, the present work explores the use of image classification models designed to help experts to find the event(s) of interest in under water inspection videos. These models can be embedded in the ROV or on the platform to perform real-time inference,which can speed up the ROV, monitor notification time, and greatly reduce verification costs. However, there are some challenges inherent to the problem of classification of images of armored submarines, such as: balanced labeled data are expensive and scarce; the presence of noise among the data; high intraclass variance; and some physical characteristics of the water that achieved certain specificities in the captured images. Therefore, traditional supervised models may not be able to fulfill the task. Motivated by these challenges, we seek to solve the underwater image classification problem using models that require less supervision during their training. In this work, they are explorers of the DINO methods (Self-Distillation with NO labels, self-supervised) anda new multi-label version proposed for PAWS (Predicting View AssignmentsWith Support Samples, semi-supervised), which we propose as mPAWS (multi-label PAWS). The models are evaluated based on their performance as features extractors for training a simple classifier, formed by a dense layer. In the experiments carried out, for the same architecture, a performance was obtained that exceeds by 2.7 percent the f1-score of the supervised equivalent.

A tarefa de classificação em Aprendizado de Máquina consiste da criação de modelos computacionais capazes de identificar automaticamente a classe de objetos pertencentes a um domínio pré-definido a partir de um conjunto de exemplos cuja classe é conhecida. Existem alguns cenários de classificação nos quais cada objeto pode estar associado não somente a uma classe, mas a várias classes ao mesmo tempo. Adicionalmente, nesses cenários denominados multirrótulo, as classes podem ser organizadas em uma taxonomia que representa as relações de generalização e especialização entre as diferentes classes, definindo uma hierarquia de classes, o que torna a tarefa de classificação ainda mais específica, denominada classificação hierárquica. Os métodos utilizados para a construção desses modelos de classificação são complexos e dependem fortemente da disponibilidade de uma quantidade expressiva de exemplos previamente classificados. Entretanto, para muitas aplicações é difícil encontrar um número significativo desses exemplos. Além disso, com poucos exemplos, os algoritmos de aprendizado supervisionado não são capazes de construir modelos de classificação eficazes. Nesses casos, é possível utilizar métodos de aprendizado semissupervisionado, cujo objetivo é aprender as classes do domínio utilizando poucos exemplos conhecidos conjuntamente com um número considerável de exemplos sem a classe especificada. Neste trabalho são propostos, entre outros, métodos que fazem uso do aprendizado semissupervisionado baseado em desacordo coperspectiva, tanto para a tarefa de classificação multirrótulo plana quanto para a tarefa de classificação hierárquica. São propostos, também, outros métodos que utilizam o aprendizado ativo com intuito de melhorar a performance de algoritmos de classificação semissupervisionada. Além disso, são propostos dois métodos para avaliação de algoritmos multirrótulo e hierárquico, os quais definem estratégias para identificação dos multirrótulos majoritários, que são utilizados para calcular os valores baseline das medidas de avaliação. Foi desenvolvido um framework para realizar a avaliação experimental da classificação hierárquica, no qual foram implementados os métodos propostos e um módulo completo para realizar a avaliação experimental de algoritmos hierárquicos. Os métodos propostos foram avaliados e comparados empiricamente, considerando conjuntos de dados de diversos domínios. A partir da análise dos resultados observa-se que os métodos baseados em desacordo não são eficazes para tarefas de classificação complexas como multirrótulo e hierárquica. Também é observado que o problema central de degradação do modelo dos algoritmos semissupervisionados agrava-se nos casos de classificação multirrótulo e hierárquica, pois, nesses casos, há um incremento nos fatores responsáveis pela degradação nos modelos construídos utilizando aprendizado semissupervisionado baseado em desacordo coperspectiva / In machine learning, the task of classification consists on creating computational models that are able to automatically identify the class of objects belonging to a predefined domain from a set of examples whose class is known a priori. There are some classification scenarios in which each object can be associated to more than one class at the same time. Moreover, in such multilabeled scenarios, classes can be organized in a taxonomy that represents the generalization and specialization relationships among the different classes, which defines a class hierarchy, making the classification task, known as hierarchical classification, even more specific. The methods used to build such classification models are complex and highly dependent on the availability of an expressive quantity of previously classified examples. However, for a large number of applications, it is difficult to find a significant number of such examples. Moreover, when few examples are available, supervised learning algorithms are not able to build efficient classification models. In such situations it is possible to use semi-supervised learning, whose aim is to learn the classes of the domain using a few classified examples in conjunction to a considerable number of examples with no specified class. In this work, we propose methods that use the co-perspective disagreement based learning approach for both, the flat multilabel classification and the hierarchical classification tasks, among others. We also propose other methods that use active learning, aiming at improving the performance of semi-supervised learning algorithms. Additionally, two methods for the evaluation of multilabel and hierarchical learning algorithms are proposed. These methods define strategies for the identification of the majority multilabels, which are used to estimate the baseline evaluation measures. A framework for the experimental evaluation of the hierarchical classification was developed. This framework includes the implementations of the proposed methods as well as a complete module for the experimental evaluation of the hierarchical algorithms. The proposed methods were empirically evaluated considering datasets from various domains. From the analysis of the results, it can be observed that the methods based on co-perspective disagreement are not effective for complex classification tasks, such as the multilabel and hierarchical classification. It can also be observed that the main degradation problem of the models of the semi-supervised algorithms worsens for the multilabel and hierarchical classification due to the fact that, for these cases, there is an increase in the causes of the degradation of the models built using semi-supervised learning based on co-perspective disagreement

Muitos problemas de classificação descritos na literatura de aprendizado de máquina e mineração de dados dizem respeito à classificação em que cada exemplo pertence a um único rótulo. Porém, vários problemas de classificação, principalmente no campo de Bioinformática são associados a mais de um rótulo; esses problemas são conhecidos como problemas de classificação multirrótulo. O princípio básico da classificação multirrótulo é similar ao da classificação tradicional (que possui um único rótulo), sendo diferenciada no número de rótulos a serem preditos, na qual há dois ou mais rótulos. Na área da Bioinformática muitos problemas são compostos por uma grande quantidade de rótulos em que cada exemplo pode estar associado. Porém, algoritmos de classificação tradicionais são incapazes de lidar com um conjunto de exemplos mutirrótulo, uma vez que esses algoritmos foram projetados para predizer um único rótulo. Uma solução mais simples é utilizar o método conhecido como método Binary Relevance. Porém, estudos mostraram que tal abordagem não constitui uma boa solução para o problema da classificação multirrótulo, pois cada classe é tratada individualmente, ignorando as possíveis relações entre elas. Dessa maneira, o objetivo dessa pesquisa foi propor uma nova adaptação do método Binary Relevance que leva em consideração relações entre os rótulos para tentar minimizar sua desvantagem, além de também considerar a capacidade de interpretabilidade do modelo gerado, não só o desempenho. Os resultados experimentais mostraram que esse novo método é capaz de gerar árvores que relacionam os rótulos correlacionados e também possui um desempenho comparável ao de outros métodos, obtendo bons resultados usando a medida-F. / Many classification problems described in the literature on Machine Learning and Data Mining relate to the classification in which each example belongs to a single class. However, many classification problems, especially in the field of Bioinformatics, are associated with more than one class; these problems are known as multi-label classification problems. The basic principle of multi-label classification is similar to the traditional classification (single label), and distinguished by the number of classes to be predicted, in this case, in which there are two or more labels. In Bioinformatics many problems are composed of a large number of labels that can be associated with each example. However, traditional classification algorithms are unable to cope with a set of multi-label examples, since these algorithms are designed to predict a single label. A simpler solution is to use the method known as Binary Relevance. However, studies have shown that this approach is not a good solution to the problem of multi-label classification because each class is treated individually, ignoring possible relations between them. Thus, the objective of this research was to propose a new adaptation of Binary Relevance method that took into account relations between labels trying to minimize its disadvantage, and also consider the ability of interpretability of the model generated, not just its performance. The experimental results show that this new method is capable of generating trees that relate labels and also has a performance comparable to other methods, obtaining good results using F-measure.

Multi-label classification consists of learning a function that is capable of mapping an object to a set of relevant labels. It has applications such as the association of genes with biological functions, semantic classification of scenes and text categorization. Traditional classification (i.e., single-label) is therefore a particular case of multi-label classification in which each object is associated with exactly one label. A successful approach to constructing classifiers is to obtain a probabilistic model of the relation between object attributes and labels. This model can then be used to classify objects, finding the most likely prediction by computing the marginal probability or the most probable explanation (MPE) of the labels given the attributes. Depending on the probabilistic models family chosen, such inferences may be intractable when the number of labels is large. Sum-Product Networks (SPN) are deep probabilistic models, that allow tractable marginal inference. Nevertheless, as with many other probabilistic models, performing MPE inference is NP- hard. Although, SPNs have already been used successfully for traditional classification tasks (i.e. single-label), there is no in-depth investigation on the use of SPNs for Multi-Label classification. In this work we investigate the use of SPNs for Multi-Label classification. We compare several algorithms for learning SPNs combined with different proposed approaches for classification. We show that SPN-based multi-label classifiers are competitive against state-of-the-art classifiers, such as Random k-Labelsets with Support Vector Machine and MPE inference on CutNets, in a collection of benchmark datasets. / A classificação Multi-Rótulo consiste em aprender uma função que seja capaz de mapear um objeto para um conjunto de rótulos relevantes. Ela possui aplicações como associação de genes com funções biológicas, classificação semântica de cenas e categorização de texto. A classificação tradicional, de rótulo único é, portanto, um caso particular da Classificação Multi-Rótulo, onde cada objeto está associado com exatamente um rótulo. Uma abordagem bem sucedida para classificação é obter um modelo probabilístico da relação entre atributos do objeto e rótulos. Esse modelo pode então ser usado para classificar objetos, encon- trando a predição mais provável por meio da probabilidade marginal ou a explicação mais provavél dos rótulos dados os atributos. Dependendo da família de modelos probabilísticos escolhidos, tais inferências podem ser intratáveis quando o número de rótulos é grande. As redes Soma-Produto (SPN, do inglês Sum Product Network) são modelos probabilísticos profundos, que permitem inferência marginal tratável. No entanto, como em muitos outros modelos probabilísticos, a inferência da explicação mais provavél é NP-difícil. Embora SPNs já tenham sido usadas com sucesso para tarefas de classificação tradicionais, não existe investigação aprofundada no uso de SPNs para classificação Multi-Rótulo. Neste trabalho, investigamos o uso de SPNs para classificação Multi-Rótulo. Comparamos vários algoritmos de aprendizado de SPNs combinados com diferentes abordagens propostos para classi- ficação. Mostramos que os classificadores Multi-Rótulos baseados em SPN são competitivos contra classificadores estado-da-arte, como Random k-Labelsets usando Máquinas de Suporte Vetorial e inferência exata da explicação mais provavél em CutNets, em uma coleção de conjuntos de dados de referência.

Cette thèse traite du problème de l'apprentissage automatique supervisé dans le cas ou l'on considère plusieurs sorties, potentiellement de différent types. Nous proposons d'explorer trois différents axes de recherche en rapport avec ce sujet. Dans un premier temps, nous nous concentrons sur le cas homogène et proposons un cadre théorique pour étudier la consistance des problèmes multi-labels dans le cas de l'utilisation de chaîne de classifieurs. Ensuite, en nous plaçant dans ce cadre, nous proposons une borne de Rademacher sur l'erreur de généralisation pour tous les classifieurs de la chaîne et exposons deux facteurs de dépendance reliant les sorties les unes aux autres. Dans un deuxième temps, nous développons et analysons la performance de modèles en lien avec la théorie proposée. Toujours dans le cadre de l'apprentissage avec plusieurs sorties homogènes, nous proposons un modèle basé sur des réseaux de neurones pour l'analyse de sentiments à grain fin. Enfin, nous proposons un cadre et une étude empirique qui montrent la pertinence de l'apprentissage multi-objectif dans le cas de multiples sorties hétérogènes. / In this thesis, we study the problem of learning with multiple outputs related to different tasks, such as classification and ranking. In this line of research, we explored three different axes. First we proposed a theoretical framework that can be used to show the consistency of multi-label learning in the case of classifier chains, where outputs are homogeneous. Based on this framework, we proposed Rademacher generalization error bound made by any classifier in the chain and exhibit dependency factors relating each output to the others. As a result, we introduced multiple strategies to learn classifier chains and select an order for the chain. Still focusing on the homogeneous multi-output framework, we proposed a neural network based solution for fine-grained sentiment analysis and show the efficiency of the approach. Finally, we proposed a framework and an empirical study showing the interest of learning with multiple tasks, even when the outputs are of different types.

Métodos tradicionais de aprendizado supervisionado, chamados de aprendizado monorrótulo, consideram que cada exemplo do conjunto de dados rotulados está associado a um único rótulo. No entanto, existe uma crescente quantidade de aplicações que lidam com exemplos que estão associados a múltiplos rótulos. Essas aplicações requerem métodos de aprendizado multirrótulo. Esse cenário de aprendizado introduz novos desafios que demandam abordagens diferentes daquelas tradicionalmente utilizadas no aprendizado monorrótulo. O custo associado ao processo de rotulação de exemplos, um problema presente em aprendizado monorrótulo, é ainda mais acentuado no contexto multirrótulo. O desenvolvimento de métodos para reduzir esse custo representa um desafio de pesquisa nessa área. Além disso, novos métodos de aprendizado também devem ser desenvolvidos para, entre outros objetivos, considerar a dependência de rótulos: uma nova característica presente no aprendizado multirrótulo. Há um consenso na comunidade de que métodos de aprendizado multirrótulo têm a capacidade de usufruir de melhor eficácia preditiva quando considerada a dependência de rótulos. Os principais objetivos deste trabalho estão relacionados a esses desafios: reduzir o custo do processo de rotulação de exemplos; e desenvolver métodos de aprendizado que explorem a dependência de rótulos. No primeiro caso, entre outras contribuições, um novo método de aprendizado ativo, chamado score dev, é proposto para reduzir os custos associados ao processo de rotulação multirrótulo. Resultados experimentais indicam que o método score dev é superior a outros métodos em vários domínios. No segundo caso, um método para identificar dependência de rótulos, chamado UBC, é proposto, bem como o BR+, um método para explorar essa característica. O método BR+ apresenta resultados superiores a métodos considerados estado da arte / Traditional supervised learning methods, called single-label learning, consider that each example from a labeled dataset is associated with only one label. However, an increasing number of applications deals with examples that are associated with multiple labels. These applications require multi-label learning methods. This learning scenario introduces new challenges and demands approaches that are different from those traditionally used in single-label learning. The cost of labeling examples, a problem in single-label learning, is even higher in the multi-label context. Developing methods to reduce this cost represents a research challenge in this area. Moreover, new learning methods should also be developed to, among other things, consider the label dependency: a new characteristic present in multi-label learning problems. Furthermore, there is a consensus in the community that multi-label learning methods are able to improve their predictive performance when label dependency is considered. The main aims of this work are related to these challenges: reducing the cost of the labeling process; and developing multi-label learning methods to explore label dependency. In the first case, as well as other contributions, a new multi-label active learning method, called score dev, is proposed to reduce the multi-labeling processing costs. Experimental results show that score dev outperforms other methods in many domains. In the second case, a method to identify label dependency, called UBC, is proposed, as well as BR+, a method to explore this characteristic. Results show that the BR+ method outperforms other state-of-the-art methods