The Prolegomena begin by pointing out the present lack of detailed, critical work on Plotinus., Then, after a resumé of the events of Plotinus' life, the problem of the date of composition of V 1, and its title, are discussed. Space is devoted to discussion of the purpose of the treatise, which, despite its title, is protreptic, to lead the soul to the Intelligible World and beyond by reminding it of its high status. The methodology of the Commentary is outlined, and a list of passages is given in which textual readings have been proposed which differ from those in the text of Henry and Schwyzer. The Prolegomena conclude with a detailed analysis of the contents of the treatise, included in order to show that the treatise is not a mere random collection of thoughts. There follows a translation which aims not so much to be stylish - for Plotinus was no stylist - but to give an accurate idea of what Plotinus actually wrote. The bulk of the thesis is taken up with the Commentary. The Commentary is exegetical, discussing difficulties in the treatise line by line. Since by the time Plotinus wrote his philosophical ideas were already formulated, it contains as many cross-references as possible to other treatises in the Plotinian corpus. Each chapter begins with a short introduction, and,in the body of the work, textual difficulties and the readings of previous editors, as well as difficulties of philosophical interpretation, are fully discussed. The translations of Ficino, Bréhier, Harder, Cilento and MacKenna are taken into account. Among the longer notes might be mentioned the note on 3,8 on the meaning of logos, that on the relationship between the reasoning and the undescending soul (on 3,13) 9 and the treatment of the difficult passages 6,17-19 and 7,11-17. The thesis concludes with a full bibliography.

Thesis (Ph. D.)--University of Texas at Austin. / Description based on print version record. Includes bibliographical references (leaves 164-166).

Although one-to-one technology programs are rapidly expanding in secondary schools, the literature about how to effectively leverage these programs to improve teaching and learning is relatively small. Little guidance is available for school leaders attempting to improve teachers' willingness and ability to incorporate technology effectively into their instruction. The purpose of this mixed-methods case study was to discovery what supports school leaders provide to promote high levels of computer self-efficacy and transformational digital pedagogies in one-to-one learning environments. Data were collected from English language arts, Social Studies, and science teachers in three high schools in a suburban school district in northeast Texas using an online survey, eight virtual semi-structured interviews, and two virtual focus group interviews. Data were analyzed using descriptive statistics and deductive and inductive analysis. The findings of the study reveal most teachers perceived their ability to effectively deliver digital instruction as strong, and most were able to incorporate technology into their lessons at transformational levels. The following themes emerged from data regarding teachers' perceptions of support: shared vision, realistic and supportive climate, collaboration, encouragement, job-embedded professional learning, continuous improvement, equity, and safe, legal, and ethical use. The findings of this study serve as a foundation for understanding how school leaders can best support teachers as they attempt to integrate one-to-one technology into their lessons.

<p>”One-to-one marketing” är en marknadsföringsidé där relationen mellan kund och leverantör står i fokus. Den kunskap om en specifik kund som leverantören får via relationen kan användas för att utforma erbjudanden anpassade för just den kunden. Erbjudandena är ämnade att påverka relationen positivt och göra kunden lojal till leverantören. Nya tekniska hjälpmedel har medfört att information om kundens preferenser kan lagras och bearbetas för att därefter användas till att utforma dessaerbjudanden. ”One-to-one marketing” är dock förknippat med vissa svårigheter och problem. Ett specialanpassat erbjudande kan uppfattas felaktigt och integritetskränkande mot kunden och på såsätt påverka relationen negativt. Vi har studerat ICAs ”One-to-one marketing”-kampanj ”Mina varor” för att se huruvida denna stärker relationen till ICAs stamkunder eller om kampanjen inverkat negativt på relationen.Vi har utifrån en enkätundersökning kommit fram till att vårt urval av respondenter främst haft åsikter om utformningen av rabatterna. De problem som uppfattats av stamkunderna i denna undersökning har främst varit relaterade till att rabatterna uppfattats som konstiga och inte representativa.Uppsatsen indikerar på att detta bör förbättras för att kampanjen ska bli mer effektiv. Integritetsproblemet kommenterades endast av ett fåtal respondenter och har i denna uppsats inte visat sig som ett stort problem. Inga stora risker att relationen har försämrats med stamkunderna kan ses och undersökningen visade generellt positiva svar för ICAs del. Kampanjen kan dock förbättras genom mer representativa personliga rabatter samt att ICA med ytterligare dialog kan binda lojala kunder starkaretill relationen.</p>

Thesis advisor: Richard Jackson / A significant body of research has examined the impact of technology on pedagogy (Cuban, 1999; Enyedy, 2014), student achievement (Schachter, 1999; Cheung & Slavin, 2013, OECD, 2015), and equity (Reich, Murnane & Willett, 2012; Van Deursen & Van Dijk, 2011) with both positive and negative results within each domain. Research has also examined the impact of technology on the success of students with disabilities in various domains (Corn, Tagsold, & Argueta, 2012; Hargreaves & Braun, 2012; Harris & Smith, 2004; Penuel, 2006). However, no research has assessed the impact of one to one technology, in particular, on the self-efficacy of students with specific learning disabilities in educational settings. This dissertation examined the experience of nine middle school students with specific learning disabilities in the first year of a one to one laptop program. Among the guiding questions for this research was the following: What characteristics of 1:1 programs present particular challenges or opportunities for students with learning disabilities? A series of interviews with students, parents, and teachers, as well as pre and post-surveys gauging student self-efficacy, were organized within the frame of activity theory and analyzed using a case-study narrative approach. Findings from the research suggest the presence of several critical conditions that support student self-efficacy in this one to one program. These critical conditions include the presence of a culture of collaboration, putting the needs of teachers first in terms of comfort with technology, providing a system of professional development for both students and teachers, encouraging the philosophy of a growth mindset in relation to technology, and adopting a Universal Design for Learning (UDL) framework as a model for curriculum design that emphasizes equity through flexibility. / Thesis (PhD) — Boston College, 2017. / Submitted to: Boston College. Lynch School of Education. / Discipline: Teacher Education, Special Education, Curriculum and Instruction.

Thesis advisor: Jianmin Gao / Thesis advisor: Eranthie Weerapana / Cyclic peptides provide a privileged scaffold when optimizing interactions with various biological targets. Their rigidified structure decreases the entropic cost of binding by preorganizing residues in a fixed conformation, which may enhance binding affinity. These molecules occupy a larger chemical space than typical small molecule drugs and may provide good candidates for inhibiting protein-protein interactions or being able to interact with previously undruggable targets. Given the benefits of these structures we aim to develop a one-bead-one-compound peptide library for screening against relevant biological targets. Herein we describe several routes to achieving cyclic peptides through side chain interactions and head-to tail amide bond linkages. Additional considerations for the development of the on resin library such as linker strategies and sequencing methods will be discussed. / Thesis (MS) — Boston College, 2015. / Submitted to: Boston College. Graduate School of Arts and Sciences. / Discipline: Chemistry.

One-to-one marketing är en extrem variant av relationsmarknadsföring.Begreppet myntades i början av 1990-talet och ligger till grund för en ny synpå marknadsföring. Många företag har försökt att använda sig av teoriernakring begreppet, men få har hittills lyckats fullt ut. One-to-one marketingfrämjas av att kunden inte behöva återupprepa sig varje gång man köperföretagets produkt eller tjänst. Detta medför att kunden kan tjäna på att vara ien relation med ett företag som använder sig av one-to-one marketing. Syftetmed uppsatsen är att undersöka om vårt valda företag planerar att användasig av one-to-one marketing i sin marknadsföring och om deras uppfattningav begreppet stämmer överens med vad teorierna säger. Detta kan vararelevant då man på senare tid kan se att marknadsföringen har rört sig bortfrån massmarknadsföringsstrukturen till en mer kundanpassadmarknadsföring.Det företag som vi har valt att studera är ICA, som håller på att utvecklaone-to-one marketing i sin marknadsföring. Vi har valt detta företag dels föratt vi ville undersöka ett stort företag som säkerligen har återkommandekunder, samt för att de har arbetat med relationsmarknadsföring i ett antal år.När vi genomförde vår kvalitativa undersökning utgick vi från en intervjumed en anställd på ICA:s Customer Relationship Management avdelning föratt få en inblick i hur ICA tänker kring sin utveckling av one-to-onemarketing.Det visar sig i vår undersökning att några av grunderna enligt one-to-onemarketing begreppet enligt teorin inte kan anpassas på ICA. Samtidigt somderas synätt på one-to-one marketing inte alltid överensstämmer med vadteorierna säger om begreppet, har de ändå en bra uppfattning om hur manska skräddarsy erbjudande till sina kunder. / Uppsatsnivå: C

One-to-one electronic devices have become commonplace in many educational settings across the globe, but it has been unclear how long-term teaching practices using such devices have evolved and how they relate to recognized best practices for using technology in the classroom. This study examined what a generation of teachers has over time identified as best applications of using these devices; their benefits, drawbacks, and challenges; and whether their use reflected previously identified best application of technologies in the classroom. This case study, conducted in one school system in New England, used the theories of Substitution, Augmentation, Modification and Redefinition (SAMR) and Technology, Pedagogy, and Content Analysis (TPACK) as a conceptual framework. Participants included two groups, one composed of four teachers who have taught only after implementation of one-on-one laptop use and one composed of four teachers who taught both before and after device implementation, selected to determine whether differences existed in attitudes and practices based on types of teaching experience. Data sources included interviews and observations. Results of inductive analyses indicated both veteran and established teachers embraced the use of one-to-one devices in their teaching, but both groups lacked the knowledge of SAMR and TPACK theories to best apply them in the classroom. This study contributes to the field by including recommendations for stronger teacher technology implementation, including more in-depth training and support with application of TPACK and SAMR theories in classroom pedagogy.

”One-to-one marketing” är en marknadsföringsidé där relationen mellan kund och leverantör står i fokus. Den kunskap om en specifik kund som leverantören får via relationen kan användas för att utforma erbjudanden anpassade för just den kunden. Erbjudandena är ämnade att påverka relationen positivt och göra kunden lojal till leverantören. Nya tekniska hjälpmedel har medfört att information om kundens preferenser kan lagras och bearbetas för att därefter användas till att utforma dessaerbjudanden. ”One-to-one marketing” är dock förknippat med vissa svårigheter och problem. Ett specialanpassat erbjudande kan uppfattas felaktigt och integritetskränkande mot kunden och på såsätt påverka relationen negativt. Vi har studerat ICAs ”One-to-one marketing”-kampanj ”Mina varor” för att se huruvida denna stärker relationen till ICAs stamkunder eller om kampanjen inverkat negativt på relationen.Vi har utifrån en enkätundersökning kommit fram till att vårt urval av respondenter främst haft åsikter om utformningen av rabatterna. De problem som uppfattats av stamkunderna i denna undersökning har främst varit relaterade till att rabatterna uppfattats som konstiga och inte representativa.Uppsatsen indikerar på att detta bör förbättras för att kampanjen ska bli mer effektiv. Integritetsproblemet kommenterades endast av ett fåtal respondenter och har i denna uppsats inte visat sig som ett stort problem. Inga stora risker att relationen har försämrats med stamkunderna kan ses och undersökningen visade generellt positiva svar för ICAs del. Kampanjen kan dock förbättras genom mer representativa personliga rabatter samt att ICA med ytterligare dialog kan binda lojala kunder starkaretill relationen.

Abstract Due to the change of the times, the medical environment in Taiwan has adapted the mainstream of ¡§patient-centered¡¨ concept. It seems to become a slogan for all medical practitioners. However, little has really changed despite lip service paid to the process of medical improvement. The author has been treating patients with kidney failure for almost twenty years. As being a nephrologist, he realizes that the quality of medical care, the quality of life and the mortality rate are highly related to the length of going on hemodialysis for uremic patients. It means the longer a uremic patient goes on hemodialysis, the lower uremic toxin level and the better quality of life a patient can receive. However, due to the limitation of arranging schedule for all of the medical staff at hospitals, many uremic patients can not have enough delivered dialysis doses they need. By re-scheduling hospital staff¡¦s working hours, uremic patients¡¦needs can be easily met in order to achieve the truly ¡§one-by-one¡¨customized service. It seems to move a step closer to the concept of¡§patient-centered¡¨ service. In Taiwan, the current health insurance system, the total payment clause, and the increasing medical cost seem to play a crucial part in running hospitals. We can avoid causing medical accidence by providing sensible working hours and duties to hospital staff. After carrying out the customized working schedule, the hospital management has successfully reduced the working hours of all staff. It definitely creates a win-win situation for the hospital management and employees. This study is mainly observative, descriptive, cross-sectional, observing the connection and influence of personal and environmental factors on (1) the satisfactory degree of uremic patients, (2) the criterion of the quality of medical treatment¡X(A) the mortality rate of uremic patients (B) the index of KT/V and Albumin, HCT (C) the infection rate (D) the possibility of unpredictable in-hospital accidents¡X(3) potential uremic patients; CKD the chronic uremic patients¡¦ satisfaction (4) the satisfactory degree of nurses. This is a retrospective study, comparing the difference between before and after executing the customized schedule. It focus on the two periods¡X(1) From Jan. to April, 2001 (2) From Jan. to April, 2007 to find out the difference by looking at four variances¡X(A) Nursing hours (B) Mortality rate (C) Accidental rate (D) Job-quitting rate of nurses. To verify the workability and result of this system, we compare the difference between Kaohsiung Armed Forces General Hospital and a private dialysis clinic in Kaohsiung by analyzing the result of questionnaires. The finding shows that there has been a significant improvement on patients¡¦ satisfaction and the quality of medical treatment after carrying out the customized schedule. It¡¦s an undeniable social responsibility to all doctors and nurses to prevent even cure diseases. Taiwan has already had the highest rate of kidney failure around the world; therefore, the customized schedule can save time and manpower to provide better care to chronic kidney disease patients. Moreover, it can also make uremic patients suffer less while going on dialysis or delay the timing for patients going on dialysis. Key word¡G¡§one-by-one¡¨customized service¡Bhemodialysis¡Bpatient-centered