Tanto os motores turbo-jato quanto os turbo-fan, são os maiores responsáveis pela geração de ruído durante a decolagem, segmento de subida e de aceleração de uma aeronave. Devido a isto, o problema de ruído em jatos vem sendo intensamente investigado ao longo dos últimos anos. Já na fase do pouso, o slat é uma das fontes de ruído mais importantes. Para este caso, na maioria das aplicações práticas, existe o descolamento da camada limite no intradorso do slat a partir de onde se desenvolve uma camada de mistura. Ainda assim, existem inúmeros aspectos de tais escoamentos que precisam de investigação. Uma abordagem frequentemente feita para o estudo da instabilidade hidrodinâmica e ruído em jatos é o estudo de metade do jato. A estratégia consiste em estudar os fenômenos na camada de mistura, o que é uma aproximação razoável quando o jato tem diâmetro muito grande comparado à espessura da camada cisalhante que se desenvolve nas bordas do jato. Assim, alguns aspectos do ruído gerado pelos modos axi-simétricos de instabilidade são em grande parte reproduzidos. Um aspecto aparentemente jamais estudado antes é o efeito do emparelhamento de vórtices de diferentes geometrias na camada de mistura. Caso o efeito da modulação dos vórtices produzisse um padrão de ruído com características diferentes no emparelhamento, um controle ativo de escoamento por excitação periódica poderia ser usado para reduzir o ruído em jatos. O objetivo do presente trabalho é investigar tal efeito. A idéia é investigar este emparelhamento de vórtices na camada de mistura em desenvolvimento temporal bi-dimensional. Com isto foi possível visualizar um emparelhamento isolado de outros emparelhamentos e sem o efeito Doppler (presente na camada de mistura em desenvolvimento espacial). O método adotado foi a simulação numérica direta (DNS) das equações de Navier Stokes compressíveis na forma não-conservativa escritas na formulação característica. Os resultados mostram que a modulação dos vórtices não produz alteração significativa do ruído gerado no emparelhamento. / Turbo-fan and turbo-jet engines are the most important noise sources during the aircraft take off, climb and acceleration segments. Owing to this fact, the jet flow noise has been studied in the past years. For the landing stage, the slat is an important sound source. In this case, the slat leading edge frequently experiences a boundary layer deattachment causing the development of a mixing layer inside the slot. Nevertheless, there are many aspects of such phenomenon that have not been studied yet. Mixing layers constitutes an usual approach for jet flow instability in aeroacoustics studies. The stategy is to study the mixing layer in order to understand the jet-flow. This strategy becomes better as the ratio between the jet diameter and mixing layer thickness becomes larger. This approach is only reazonable for the jet flow axi-symetric unstable modes. The effect of vortex modulation on the vortex pairing sound production has not been found in the literature. If such effect could cause a significant change in the sound generation patterns, an active flow control system could be developed in order to enhance the jet noise performance. The purpose of the present work was to investigate such effect. It was also possible to observe a single vortex pairing inside a wide domain without the Doppler effect. The strategy was to study the vortex pairing in a bi-dimensional mixing layer under temporal development. The method used was the direct numerical simulation (DNS) of the compressible bidimensional (2D) Navier Stokes equations written in a nonconservative form of the characteristics formulation. The results showed that the vortex modulation did not produce a significant change on the vortex pairing sound.

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Le logarithme discret sur les courbes elliptiques fournit la panoplie standard de la cryptographie à clé publique: chiffrement asymétrique, signature, authentification. Son extension à des courbes hyperelliptiques de genre supérieur se heurte à la difficulté de construire de telles courbes qui soient sécurisées. Dans cette thèse nous utilisons la théorie des fonctions thêta développée par Mumford pour construire des algorithmes efficaces pour manipuler les variétés abéliennes. En particulier nous donnons une généralisation complète des formules de Vélu sur les courbes elliptiques pour le calcul d'isogénie sur des variétés abéliennes. Nous donnons également un nouvel algorithme pour le calcul efficace de couplage sur les variétés abéliennes en utilisant les coordonnées thêta. Enfin, nous présentons une méthode de compression des coordonnées pour améliorer l'arithmétique sur les coordonnées thêta de grand niveau. Ces applications découlent d'une analyse fine des formules d'addition sur les fonctions thêta. Si les résultats de cette thèse sont valables pour toute variété abélienne, pour les applications nous nous concentrons surtout sur les jacobienne de courbes hyperelliptiques de genre~$2$, qui est le cas le plus significatif cryptographiquement. / The discrete logarithm on elliptic curves give the standard protocols in public key cryptography: asymmetric encryption, signatures, ero-knowledge authentification. To extends the discrete logarithm to hyperelliptic curves of higher genus we need efficient methods to generate secure curves. The aim of this thesis is to give new algorithms to compute with abelian varieties. For this we use the theory of algebraic theta functions in the framework of Mumford. In particular, we give a full generalization of Vélu's formulas for the computation of isogenies on abelian varieties. We also give a new algorithm for the computation of pairings using theta coordinates. Finally we present a point compression method to manipulate These applications follow from the analysis of Riemann relations on theta functions for the addition law. If the results of this thesis are valid for any abelian variety, for the applications a special emphasis is given to Jacobians of hyperelliptic genus~$2$ curves, since they are the most significantly relevant case in cryptography.

Although codon usage bias has been shown to persist through non-random mutations and selection, many avenues of research into the applications of codon usage bias have remained unexplored. In this dissertation, we present several new applications of codon usage bias and their practical uses in a phylogenetic construct. We first review the literature and provide background into other software applications of codon usage bias in Chapter 1. In Chapter 2, we show that in tetrapods, codon aversion in orthologs is phylogenetically conserved. We further this analysis in Chapter 3 by exploring codon use and aversion across the Tree of Life, providing frameworks for other researchers to analyze different species subsets. We present a novel algorithm to recover species relationships using codon aversion, without regard to orthologous relationships in Chapter 4. We present several other algorithms in Chapter 5 to also recover species relationships using biases in codon pairing. Chapter 6 analyzes the relationship between codon usage bias in viruses that infect humans and proteins found in tissues that they infect. In Chapter 7, we present our discovery of a conservation in coding sequence lengths in orthologous genes that allowed us to accurately recover orthologous gene relationships and reduce overall ortholog identification runtime by over 96%. In Chapter 8 we discuss a novel algorithm for extracting a ramp of slowly-translated codons located at the beginning of gene sequences, allowing researchers to quickly identify translational bottlenecks. Finally, Chapter 9 touches on future applications of codon usage bias in phylogenetics. This dissertation represents a major vertical leap in phylogenetics by providing a framework and paradigm shift toward utilizing codon usage and coding sequence length biases in future analyses.

The aim of the thesis is analysis and inventory security risks of Bluetooth technology, assembly Bluetooth adapter and proposal and poposal of testing procedures, which will helps evaluate security of tested device.

In recent years, due to the development of molecular methods, a great level of cryptic diversity across multiple taxa was discovered. One of these groups are freshwater amphipods. Amphipods due to lower dispersal and recolonization abilities present a suitable model system for studying potential ecological interactions among genetically distant lineages during their secondary contact. In this thesis, I studied the cryptic species complex Gammarus fossarum in a contact zone of several genetically divergent lineages known from the previous research in the Vsetin region. I focused on two main questions: Firstly, whether there are preferences among individuals from different lineages for sexual partners from the same lineage rather than from the different one (i.e., I test for the potential existence of prezygotic reproduction barrier between the lineages). I tested this hypothesis by collecting pairs from natural contact zone and also (in a limited extent) by an aquarium experiment. Secondly, I tested whether these lineages differ in mesohabitat (pool versus riffle) distribution in syntopy, which may indicate competition among lineages and potential diversification of their ecological niches. Animals from nine localities (with expected contact of two lineages per locality) were examined. In more than...

The Chief Security Officer Problem (CSO) consists of a CSO, a group of agents trying to communicate with the CSO and a group of eavesdroppers trying to listen to the conversations between the CSO and its agents. Through Lemmas and Theorems, several Information Theoretic questions are answered.

A successful supercritical fluid extraction method includes removal of the analyte from the matrix into the bulk fluid as well as trapping or concentration of the analyte prior to analysis. In the first phase of this research, the trapping capacities of three solid-phase traps (glass beads, 50/50 (w/w) glass beads/octadecylsilica), 50/50 (w/w) Porapak Q®/glass beads) were determined as a function of trap composition for a mixture of components varying in polarity and volatility. The Porapak Q®/glass beads mixture was found to be the most successful solidphase investigated exhibiting the highest trapping capacity. The use of the Porapak Q®/glass beads as a solid-phase trap was investigated in later extraction studies in this dissertation. The extraction of highly polar, multifunctional analytes may not be completely successful with modified carbon dioxide, therefore, a secondary modifier (i.e. additive) may be added directly to the extraction fluid in hopes of improving the recoveries. In the second phase of this research, the effect of secondary modifiers in the subcritical fluid extraction of lovastatin from in-house prepared tablet powder mixtures and MEVACOR® tablets was investigated. The effect of in-line methanol-modifier percentage, additive type (acidic, basic, neutral) to the in-line methanol, and additive concentration on the extraction efficiency were examined. The extraction recoveries of lovastatin from MEVACOR® tablets were shown to be highly dependent on methanol concentration and additive type. Isopropylamine was shown to be the most successful additive investigated. An optimized and reproducible extraction method was developed. The extraction of ionic compounds with carbon dioxide may be difficult due to the high polarity of the compounds. In the third phase of this research, the addition of ion-pairing additives to the matrix in hopes of forming an ion-pair complex of reduced analyte polarity was investigated. Therefore, a screening study consisting of a fractional-factorial design was performed in order to identify the factors which contribute most to the recovery of an anionic species, triphenylphosphinetrisulfonate (TPPTS), from a spiked-sand surface employing supercritical fluid extraction with carbon dioxide. The experimental parameters investigated were: type of ion-pairing additive (i.e. tetralkylammonium hydrogen sulfates) and its concentration, carbon dioxide density, extraction temperature, static extraction time, CO₂ mass used, liquid CO₂ flow rate, and the volume of methanol spiked into the matrix prior to extraction. Of the eight factors investigated, four factors were identified as significantly affecting the recovery of the anionic species. They were: 1) ion-pairing reagent added to the spiked sand surface and its concentration; 2) static extraction time; and 3) volume of methanol present in the extraction vessel. The experimental parameters and settings identified as influential by the statistical approach were later shown in concert to yield 100% recovery of TPPTS from the spiked-sand. In the fourth phase, the extraction of a cationic species, pseudoephedrine hydrochloride, from spiked-sand and Suphedrine tablets, with pure and methanol-modified CO₂ was examined. Once the extraction was shown to feasible, several strategies were compared in terms of their effectiveness in enhancing the analyte's extractability. The first strategy involved the addition of ion-pairing additives. Several sodium salts of alkylsulfonic acids varying in lipophilicity and concentration were investigated. The addition of 1-heptanesulfonic acid, sodium salt, in methanol, in a 5:1 mole ratio of reagent to analyte was shown to be the most useful in recovering the drug from the spiked-sand. The second strategy considered the influence of acids and bases and other modifier compositions such as a methanol/water mixture with or without 1-heptanesulfonic acid, sodium salt, on the pseudoephedrine recovery. The recoveries obtained from the drug spiked-sand were shown to comparable in the presence of a methanol/water solution, a tetrabutylammonium hydroxide in methanol solution, and a methanol solution with 1-heptanesulfonic acid, sodium salt. Next the extraction of pseudoephedrine hydrochloride from Suphedrine tablets was performed with pure and modified CO₂. Similar to the sand-spike studies, the effect of the addition of the ion-pairing reagent and other in-cell modifiers were examined. Once again, the recoveries obtained when the matrix was in the presence of a methanol/water mixture and a methanol solution containing 1-heptanesulfonic acid, sodium salt were similar. Finally, the identity of the extracted analyte was determined via IR analyses, and it was shown that pseudoephedrine hydrochloride was indeed extractable from the tablets with in-line modified CO₂ in the absence of any in-cell modifier. In the last phase of this research, a supercritical fluid chromatographic separation with evaporative light scattering detection was developed for the separation of five phospholipids varying in polarity and ionic characteristics. Several parameters were investigated and shown to be influential in the separation. They were: 1) stationary phase composition, 2) addition of an acidic additive and its concentration, 3) mobile phase ramp rate, and 4) column outlet pressure. / Ph. D.

Masters of Science / The main purpose of this thesis is to study the interplay between relational structures and topology, and to portray pairings in terms of some finite poset models and order preserving maps. We show the interrelations between the categories of topological spaces, closure spaces and relational structures. We study the 4-point non-Hausdorff model S4 weakly homotopy equivalent to the circle s'. We study pairings of some objects in the category of relational structures, similar to the multiplication of Hopf spaces in topology. The multiplication S4 x S4 ---7 S4 fails to be order preserving for posets. Nevertheless, applying a single barycentric subdivision on S4 to get Ss, an 8-point model of the circle enables us to define an order preserving poset map Ss x Ss ---7 S4' Restricted to the axes, this map yields weak homotopy equivalences Ss ---7 S4' Hence it is a pairing. Further, using the non-Hausdorff join Ss ® Ss, we obtain a version of the Hopf map Ss ® Ss ---7 §S4. This model of the Hopf map is in fact a map of non-Hausdorff double mapping cylinders.

Background Mentorship is used to ease entry to practice for new nursing graduates. However, little is known about the process of pairing with experienced nurses. The aim of this dissertation is to explore mentorship pairing processes for new nursing graduates and experienced nurses. Methods 1. A quality improvement project was conducted using organizational data to describe the impact of the New Graduate Guarantee program at The Ottawa Hospital from 2013 to 2018 on new graduate nurses and organizational outcomes. 2. An interpretive descriptive study was conducted to develop an in-depth understanding of mentorship pairing practices specific to nursing occurring in a clinical setting that will ultimately inform future mentorship pairing practices. 3. A systematic review was conducted to determine the effect of mentorship pairing processes on the mentoring relationship and outcomes at the level of the new nursing graduate, mentor and organization. Findings 1. From 2013 to 2017, 66 nurses were hired directly into operational vacancies and 579 new graduate nurses were paired with a mentor in the New Graduate Guarantee program. The two-year turnover rate for new graduates who participated in the New Graduate Guarantee program (21.5%, N=92/427) was lower than new graduate turnover rates reported in the literature. 2. Interviews with 13 new graduate nurses and 12 mentors revealed a lack of awareness of current nursing mentorship pairing processes. Six nurse leaders described pairing processes using third party pairing. Participants suggested preparation, socialization and self-selection are key components to consider for future practice. 3. Of 2583 citations screened, no studies evaluated the nursing mentorship pairing process. Research is required to determine effective mentorship pairing processes in nursing. Conclusion Although 579 nurses were hired through the New Graduate Guarantee nursing mentorship program, the 13 new graduates and 12 mentors interviewed were unaware of the process used for pairing. Furthermore, no studies have evaluated mentorship pairing processes. Ninety percent of new graduates hired participated in the New Graduate Guarantee program. Future research is required to trial pairing processes proposed by nurse leaders, new graduates and experienced nurses and to develop and validate tools to evaluate the outcomes of these pairings.