Peter Thomas Radcliffe's Thesis (Ph. D.)--University of Wisconsin--Madison, 1974. / Typescript. Vita. eContent provider-neutral record in process. Description based on print version record. Includes bibliographical references (leaves lv-lxiii) and index.

Thesis--University of Rochester, 1959. / Bibliography: v. 1., l. 274-278.

Thesis--University of Texas. / Vita. Part 2 (leaves 247-393) contains the author's transcription of Rener's motets into modern notation in score. Includes bibliography.

Thesis (Ph. D.)--University of North Carolina, Chapel Hill, 1974. / Includes "transcriptions of all [Cara's] compositions that are not available in modern editions ..." Transcription of documents: v. 1, leaves 267-373. Includes bibliographical references (v. 1., leaves [374]-408) and indexes.

Thesis--University of Texas. / Vita. Part 2 (leaves 247-393) contains the author's transcription of Rener's motets into modern notation in score. Includes bibliography.

This study examines the economic and social aspects of part-time farming in two municipalities in the Fraser Valley region of British Columbia. The study was undertaken in 1970 under the auspices of the British Columbia Department of Agriculture and the Department of Agricultural Economics at the University of British Columbia. The primary purpose of the study was to provide descriptive information about part-time farmers and to provide some framework within which policy decisions could be made. The study examines the physical characteristics of the part-time farm, the socio-economic characteristics of the part-time farm operator and his family, and the financial aspects of part-time farming. Some analysis is undertaken with respect to the findings of the survey and, where possible, these are related to census data for comparison between part-time farms and all census farms for the same area. The main conclusions drawn from these analyses were that part-time farmers were only distinguishable from the census population farmers on the basis of direct financial aspects of their farms. This was reflected in the much lower levels of farm sales and expenses experienced by part-time farmers. Several characteristics of both census farms and part-time farms were significantly different between the two municipalities. There were strong indications that neither of the two groups are homogeneous between regions. Consequently, it is difficult to envisage a single definition of farming, much less part-time farming, being formulated which will have application in such a diversified agricultural mosaic as is found in British Columbia. The study concludes by questioning the validity of a policy which segments the farm community on the basis of the farm operator having an off-farm job. The study suggests that the only meaningful indicator as to whether or not farm land resources are being effectively utilized is productivity as measured by the usual economic criteria of gross and net dollar receipts. / Land and Food Systems, Faculty of / Graduate

No description available.

Visual perception theory distinguishes between two distinct levels of object processing: holistic, based on global shape, and configural, based on local features and/or component parts. Empirical evidence suggests that different cortical regions may support these levels; holistic processing correlates with activation in the lateral occipital-temporal cortex (LOC), whereas configural processes correspond to activation in the parietal lobe, particularly the intraparietal sulcus (IPS). This study combined theories of visual part structure with neuroimaging methods to investigate the relative contribution of holistic and configural processing in an ecologically valid object recognition task. Rather than rely on stimuli specifically designed to evoke holistic or configural processing, this study used photographs of objects selected without a priori assumptions concerning physical part structure. Twenty participants viewed objects at fixation while undergoing fMRI, followed by a behavioral object identification task involving the same objects presented in peripheral vision. Behavioral data were analyzed according to theories of visual crowding to yield an objective estimate of the number of parts perceived within each object. Neuroimaging results revealed increased activation for holistic objects containing fewer parts in the right parietal lobe and superior temporal gyrus and bilaterally in the fusiform gyrus, suggesting a relation between holistic processing areas and object perception. Configural objects with many parts elicited increased activation in the left angular gyrus. This study, to our knowledge, is the first to investigate the cortical visual regions involved when observers engage in holistic and configural processing as a natural part of visual recognition. / Master of Science

Tesis por compendio / [EN] Self-incompatibility (SI) comprises a compendium of molecular intraspecific barriers, controlled by the S-locus, which enhances outcrossing and prevents inbreeding. Solanaceae, Plantaginaceae and Rosaceae exhibit the Gametophytic SI (GSI) type where specific recognition is controlled by S-RNases and S-locus F-box (SFB) proteins as the female and male S-determinants, respectively. On the other hand, unlinked S-locus genes known as modifier factors are also completely necessary for the mechanism to function. The GSI system seems to be basically preserved in Prunus but striking differences with Solanaceae and other Rosaceae have also been observed. On the basis of this background, this thesis is focused on the identification and characterization of modifiers involved in Prunus GSI to improve our understanding of the underlying mechanism. Previous works in apricot showed that an S-locus unlinked mutation expressed in pollen and located at the distal end of chr. 3 (M-locus) confers self-compatibility in the cv. 'Canino'. In this work, another self-compatible apricot cultivar, named 'Katy', was molecular and genetically analyzed. Similarly, an S-locus unlinked pollen-part mutation was found to cause the loss of self-incompatible response. A mapping strategy based on segregation distorted loci mapped 'Katy' mutation (referred as m-mutation) at the distal end of chr. 3, in a region overlapping with that identified for 'Canino' M-locus. A new screening was carried out to identify additional self-compatible mutants in apricot cultivar/accessions from germplasm banks. Through S-genotyping, three uncategorized S-alleles were recovered and two new mutations putatively conferring self-compatibility (SC) by affecting the male S-determinant SFB were detected. Additionally, M-genotyping showed that the same mutated m-haplotype was shared by 'Canino' and 'Katy', but also by 17 cultivars more from North-America and Western-Europe. A widely distributed haplotype M1-0 was proposed as the putative m-haplotype ancestor suggesting that it arose much later in time than SC-allele, a mutation in the S-locus also conferring SC in apricot. In order to identify this mutation, an integrative genetic, genomic and transcriptomic approach based on NGS data from 'Canino', 'Katy' and the self-incompatible apricot cultivar 'Goldrich' was carried out. This approach led to identify a unique polymorphism able to explain the self-compatible phenotype, a FaSt insertion type of 358-bp in coupling with the m-haplotype within a gene encoding a disulfide bond A-like oxidoreductase (named PaMDOr). PaMDOr was found to be differentially over expressed in mature anthers and the FaSt insertion is predicted to produce a truncated protein. These two findings also support PaMDOr as the pollen-part mutated modifier conferring SC in apricot. Furthermore, phylogenetic analyses suggest PaMDOr as a putative paralog of its contiguous gene (PaM-8), that emerged after the split of the Rosaceae and Solanaceae and which function became essential for the proper functioning of the GSI system in Prunus. Aimed to shed light on the differences and similarities between the S-RNase-based GSI systems in Rosaceae and Solanaceae, orthology relationships were analyzed for modifiers. Putative orthologs were found for NaTrxh, SBP1 and MdABCF in Prunus but a more complex evolutionary pattern was detected for 120K, NaStEP and NaPCCP. Thus, in spite of the differences, it can be hypothesized that part of the GSI modifier factors are shared by both families. As a whole, the multidisciplinary strategy developed in this thesis has allowed us to identify a novel modifier factor (PaMDOr) essential for the self-incompatible response in Prunus as the most significant contribution. In addition, new sources of SC have been detected in apricot and the orthology analysis helped to deepen our understanding on evolutionary aspects of the S-RNase-based GSI system exhibited by Prunus. / [ES] La autocompatibilidad (AI) comprende un conjunto de barreras moleculares intraespecíficas, controladas por el locus S, que favorecen la polinización cruzada y previenen de la endogamia. Solanáceas, Plantagináceas y Rosáceas presentan la llamada AI gametofítica (AIG) donde el reconocimiento específico está controlado por ARNasas-S y proteínas F-box del locus S (SFB) como los determinantes femenino y masculino, respectivamente. Por otra parte, genes no ligados al locus S, conocidos como factores modificadores, son también totalmente necesarios para la correcta regulación del mecanismo. El sistema AIG parece estar básicamente conservado en Prunus pero se han observado notables diferencias con Solanáceas y otras Rosáceas. Con estos antecedentes, el trabajo realizado en esta tesis se ha centrado en la identificación y caracterización de factores modificadores de la AIG en Prunus con el fin de mejorar nuestro conocimiento del mecanismo subyacente. Trabajos previos en albaricoquero mostraron la existencia de una mutación expresada en el polen y no ligada al locus S, que se localiza en el extremo distal del cr.3 (locus M) y que es capaz de conferir autocompatibilidad (AC) en el cultivar 'Canino'. En esta tesis, otro cultivar de albaricoquero autocompatible llamado 'Katy' fue genética y molecularmente analizado. De manera parecida a 'Canino', una mutación que afectaba a un factor no ligado al locus S expresado en el polen era el causante de la pérdida de la respuesta autoincompatible. La mutación en 'Katy' se consiguió mapear en el extremo distal del cr.3 (mutación m), una región que solapa con la identificada para 'Canino'. Una búsqueda para la identificación de nuevo mutantes autocompatibles en cultivares/accesiones de albaricoquero procedentes de bancos de germoplasma fue realizado. Por medio del genotipado del locus S, 3 alelos S no clasificados con anterioridad fueron hallados, mientras que 2 nuevas mutaciones autocompatibles que parecen haber afectado al determinante S masculino SFB fueron detectadas. Adicionalmente, el genotipado para el locus M mostró que el mismo haplotipo m mutado está compartido por 'Canino' y 'Katy' y 17 cultivares más del norte de América y el oeste de Europa. El haplotipo M1-0 ha sido propuesto como posible ancestro del haplotipo m, sugiriendo que éste surgió mucho más tarde que el alelo Sc, mutación del locus S que también confiere AC en albaricoquero. Con el objetivo de identificar esta mutación, un abordaje integral tanto a nivel genético como genómico y transcriptómico mediante datos NGS procedentes de 'Canino', 'Katy' y del cultivar de albaricoquero autoincompatible 'Goldrich' fue llevado a cabo. Esta aproximación sirvió para identificar un único polimorfismo capaz de explicar el fenotipo de AC, una inserción tipo FaSt de 358 pb en acoplamiento con el haplotipo m en un gen que codifica para una disulfide bond A-like oxidoreductase (PaMDOr). PaMDOr mostró estar diferencialmente sobre-expresado en anteras maduras, mientras que la inserción FaSt predice la formación de una proteína truncada. Estos dos hechos apoyan a PaMDOr como el factor modificador de la parte del polen que confiere AC en albaricoquero. Adicionalmente, análisis filogenéticos sugieren que PaMDOr podría ser un parálogo del gen contiguo (PaM-8) que surgió después de la división de Rosáceas y Solanáceas, cuya función ha llegado a ser esencial para el correcto funcionamiento del sistema en Prunus. A fin de arrojar cierta luz en las diferencias y similitudes entre los sistemas de AIG basado en ARNasas-S de Rosáceas y Solanáceas, las relaciones de ortología para factores modificadores fueron estudiadas. Ortólogos candidatos fueron encontrados para NaTrxh, SBP1 y MdABCF, sin embargo, un patrón evolutivo más complejo fue observado para NaStEP, 120K y NaPCCP. De modo que, a pesar de las diferencias, se puede hipotetizar que una parte de los modificadores de la AIG están comparti / [CA] L'autocompatibilitat (AI) comprèn un conjunt de barreres moleculars intraespecífiques, controlades pel locus S, que afavorixen la pol·linització creuada i prevé de l'endogàmia. Solanàcies, Plantaginàcies i Rosàcies presenten l'anomenada AI gametofítica (AIG) on el reconeixement específic està controlat per ARNases-S i proteïnes F-box del locus S (SFB) com a determinants femení i masculí, respectivament. Per un altra banda, gens no lligats al locus S, coneguts com factors modificadors, són també totalment necessaris per a la correcta regulació del mecanisme. El sistema AIG pareix estar bàsicament conservat en Prunus, però s'han observat notables diferències amb Solanàcies i altres Rosàcies. Amb estos antecedents, el treball realitzat durant aquesta tesi se ha focalitzat en la identificació i caracterització de factors modificadors de l'AIG en Prunus a fi d millorar el nostre enteniment del mecanisme subjacent. Treballs previs a l'albercoquer mostraren l'existència d'una mutació expressada al pol·len no lligada al locus S, la qual està localitzada a l'extrem distal del cr.3 (locus M) i es capaç de conferir autocompatibilitat (AC) al cultivar 'Canino'. En aquest treball, un altre cultivar d'albercoquer autocompatible anomenat 'Katy' va ser genètica i molecularment analitzat. De manera pareguda a 'Canino', una mutació que afecta a un factor no lligat al locus S expressat al pol·len era la causa de la perduda de la resposta autoincompatible. La mutació a 'Katy' es va mapetjar a l'extrem distal del cr.3 (mutació m) en una regió solapant amb la identificada per a 'Canino'. Una recerca per a la identificació de nous mutants autocompatibles en cultivars i/o accessions d'albercoquer procedents de bancs de germoplasma va ser portada a terme. Mitjançant el genotipatge del locus S, 3 al·lels S no classificats amb anterioritat van ser trobats, mestres que dos noves mutacions AC que pareixen haver afectat al determinant S masculí SFB varen ser detectades. Amés, el genotipatge del locus M va mostrar que el mateix haplotip m mutat està compartit per 'Canino' i 'Katy', però també per 17 cultivars més del nord d'Amèrica i l'oest d'Europa. El haplotip M1-0, ampliamente distribuït, ha sigut proposat com a possible ancestre del haplotip m, sugerint que aquest va sorgir més tard que el al·lel Sc, una mutació al locus S que també conferix AC a l'albercoquer. Amb l'objectiu d'identificar aquesta mutació, un abordatge integral tant a nivell genètic com genòmic i transcriptòmic mitjançant diversos tipus de dades NGS provinents de 'Canino', 'Katy' i del cultivar d'albercoquer autoincompatible 'Goldrich' va ser portat terme. Aquesta aproximació va permetre identificar un únic polimorfisme capaç d'explicar el fenotip AC, es tracta d'una inserció de 358 pb en adaptament amb el haplotip m en un gen que codifica per a disulfide bond A-like oxidoreductase (PaMDOr). PaMDOr va mostrar estar diferencialment sobre-expressat en anteres madures, mentres que la inserció FaSt prediu la formació d'una proteïna truncada. Estos dos fets recolzen a PaMDOr com al factor modificador de la part del pol·len que conferix AC en albercoquer. A més a més, anàlisis filogenètics suggerixen que PaMDOr podria ser un paràlog del seu gen contigu (anomenat PaM-8) que va sorgir després de la divisió de Rosàcies i Solanàcies, en la qual la funció ha arribat a ser fonamental per al correcte funcionament del sistema d'AIG a Prunus. A fi de tirar certa llum en quant a les diferències i similituds entre els sistemes d'AIG basats en ARNases-S de Rosàcies i Solanàcies, les relacions d'ortologia per als factors modificadors va ser estudiat. Ortòlogs candidat van ser trobats per a NaTrxh, SBP1 i MdABCF, no obstant, un patró evolutiu més complex va ser observat per a NaSTeP, 120K i NaPCCP. De tal manera que, a pesar de les diferències, es pot plantejar la hipòtesi de que una part dels modificadors de l'AIG estan / Muñoz Sanz, JV. (2016). Crossability barriers in Prunus: the role of modifiers in the regulation of the gametophytic self-incompatibility system [Tesis doctoral]. Universitat Politècnica de València. https://doi.org/10.4995/Thesis/10251/68489 / Compendio

Yes / Purpose: To compare full-time occlusion (FTO) and part-time occlusion (PTO) therapy in the treatment of amblyopia, with the secondary aim of evaluating the minimum number of hours of part-time patching required for maximal effect from occlusion. Methods: A literature search was performed in PubMed, Scopus, Science Direct, Ovid, Web of Science and Cochrane library. Methodological quality of the literature was evaluated according to the Oxford Center for Evidence Based Medicine and modified Newcastle-Ottawa scale. Statistical analyses were performed using Comprehensive Meta-Analysis (version 2, Biostat Inc., USA). Results: The present meta-analysis included six studies (three randomized controlled trials [RCTs] and three non-RCTs). Pooled standardized difference in the mean changes in the visual acuity was 0.337 [lower and upper limits: 0.009, 0.683] higher in the FTO as compared to the PTO group; however, this difference was not statistically significant (P ¼ 0.056, Cochrane Q value ¼ 20.4 (P ¼ 0.001), I2 ¼ 75.49%). Egger's regression intercept was 5.46 (P ¼ 0.04). The pooled standardized difference in means of visual acuity changes was 1.097 [lower and upper limits: 0.68, 1.513] higher in the FTO arm (P < 0.001), and 0.7 [lower and upper limits: 0.315, 1.085] higher in the PTO arm (P < 0.001) compared to PTO less than two hours. Conclusions: This meta-analysis shows no statistically significant difference between PTO and FTO in treatment of amblyopia. However, our results suggest that the minimum effective PTO duration, to observe maximal improvement in visual acuity is six hours per day.